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Dietary supplement

Full Spectrum Wild Yam 400 mg Ingredients & Drug Interactions

by Swanson Premium Brand

Full Spectrum Wild Yam 400 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Full Spectrum Wild Yam 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Full Spectrum Wild Yam 400 mg is a dietary supplement by Swanson Premium Brand with 1 active ingredient. Its ingredients are commonly taken for menopausal symptoms, menstrual cramps, hormone balance (popular belief).Based on those ingredients, 41 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wild Yam. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Full Spectrum Wild Yam 400 mg by Swanson Premium Brand

Ask about any prescription or over-the-counter medication and we check it for interactions with Full Spectrum Wild Yam 400 mg by Swanson Premium Brand — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Full Spectrum Wild Yam 400 mg by Swanson Premium Brand

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: wild yam root at 400 mg per capsule. Wild yam has been used traditionally for menopausal symptoms and hormone support, though the evidence for those uses is limited (more on that below).

The capsule also contains inactive ingredients — gelatin, rice flour, magnesium stearate, and silica — which are fillers and binders that help hold the capsule together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Wild Yam product and its label doesn't state a use — see Wild Yam's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for wild yam is mixed and incomplete. For menopausal symptoms, the data suggests it's likely ineffective — meaning the studies we have don't support its use for hot flashes or other menopause-related troubles.

For gallbladder disease, sexual dysfunction, irregular periods (dysmenorrhea), and fertility, there simply isn't enough reliable evidence to say whether it works or doesn't. If you're considering this for one of those uses, talk with your pharmacist or doctor about what the research actually supports.

The evidence, ingredient by ingredient Wild Yam

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, wild yam is generally well tolerated for short-term use in healthy adults, though long-term safety hasn't been well studied. The most common side effects are fever, headache, upset stomach, and vomiting — especially at higher doses.

Anaphylaxis (a severe allergic reaction) is rare but has been reported. The safety data advises against wild yam during pregnancy and while breastfeeding because there isn't enough information to know it's safe.

One case report noted vision loss in a woman who took a combination product containing wild yam along with several other herbs, but it's unclear what caused it.

Side effects, ingredient by ingredient Wild Yam

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wild Yam.
  • The most serious interaction on file is rated Moderate.
  • For scale: 41 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any estrogen-based medications — birth control pills, hormone replacement therapy, or other hormonal drugs — check them against this product before you start. The interaction is Moderate-severity: wild yam might increase or decrease how your estrogen medication works, and we can't predict which one will happen without knowing your specific drug.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Wild yam might appeal to you if you're exploring traditional approaches to menopausal symptoms or hormone support, but the evidence for those uses is weak. The main thing to watch is whether you take estrogen-based medications — birth control, hormone replacement therapy, or others — because wild yam may interfere with how they work.

Check your exact medications with us before you start, and talk to your pharmacist if you're pregnant, breastfeeding, or taking this long-term.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Full Spectrum Wild Yam 400 mg, straight from the product label.

Brand Swanson Premium Brand
Barcode (UPC) 087614112589
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 322728
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Full Spectrum Wild Yam 400 mg by Swanson Premium Brand, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
087614112589
IngredientAmount% DV
Wild Yam400 mg--

Other ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Swanson Premium Brand Bringing wellness to the world since 1969

FDA Statement of Identity

Herbal Supplement

Formulation

Guaranteed Purity & Potency

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Warning: Do not take this product if you are pregnant or nursing.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one capsule one to two times per day with water.

General Statements

To reorder, call toll free 1-800-437-4148 or visit our website at www,swansonvitamins.com

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Full Spectrum Wild Yam 400 mg by Swanson Premium Brand label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Full Spectrum Wild Yam 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Full Spectrum Wild Yam 400 mg by Swanson Premium Brand

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Wild Yam

Interacts with
41 drugs
400 mg per serving Form: Dioscorea villosa

Wild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for t...

Wild Yam monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Full Spectrum Wild Yam 400 mg by Swanson Premium Brand Drug Interactions

Want to check YOUR meds against Full Spectrum Wild Yam 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
41Drugs
41 Moderate

Ingredients driving the most interactions

Wild Yam 41

Individual Drug Interactions

The ingredients in Full Spectrum Wild Yam 400 mg interact with 41 drugs. Click any drug to see the details.

1 of the 1 ingredient in Full Spectrum Wild Yam 400 mg interact with drugs. Each result below shows which ingredient is responsible. Wild Yam

Each ingredient & the kinds of drugs it affects

For each ingredient in Full Spectrum Wild Yam 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wild Yam1 drug type · 41 drugs

Estrogens

Theoretically, wild yam might increase or decrease the effects of estrogen.
Wild yam root shows estrogenic and anti-estrogenic effects in vitro. Theoretically, wild yam might interfere with hormone therapy.

Likelihood Possible Evidence D
Wild Yam full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Full Spectrum Wild Yam 400 mg, from the product label.

Swanson Premium Brand

See all Swanson Premium Brand products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Full Spectrum Wild Yam 400 mg by Swanson Premium Brand: Common Questions

Does Full Spectrum Wild Yam 400 mg by Swanson Premium Brand interact with any medications?
Yes. Based on its ingredients, Full Spectrum Wild Yam 400 mg has a known interaction with 41 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Full Spectrum Wild Yam 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does wild yam actually help with hot flashes and menopausal symptoms?
The evidence suggests it's likely ineffective for menopausal symptoms. If you're looking for relief, talk with your doctor about what actually has support behind it.
Can I take this if I'm on birth control or hormone replacement therapy?
Not without checking first — wild yam can theoretically increase or decrease how your estrogen medication works. Use the interaction checker below with your exact medication name to see if there's a documented interaction.
What are the side effects?
The most common ones are fever, headache, upset stomach, and vomiting, especially at higher doses. It's generally well tolerated for short-term use, but long-term safety hasn't been well studied.
Is it safe to take while pregnant or breastfeeding?
No — the safety data advises against wild yam during pregnancy and while breastfeeding because there isn't enough information to know it's safe. Talk with your doctor or pharmacist about your options.
What does 'full spectrum' mean on this label?
That phrase usually means the product uses the whole plant material rather than just an isolated extract or compound, but the product facts here don't define it further for this specific product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Full Spectrum Wild Yam 400 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Full Spectrum Wild Yam 400 mg label
Go deeper

The Full Monographs Behind Full Spectrum Wild Yam 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wild Yam

Interacts with 41 drugs

Wild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for these uses is lacking. Despite popular cl...

Read the full Wild Yam monograph →
Sources

Sources & How We Checked

Full Spectrum Wild Yam 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wild Yam 7 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  3. Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
  4. Rosenberg Zand, R. S., Jenkins, D. J., and Diamandis, E. P. Effects of natural products and nutraceuticals on steroid hormone-regulated gene expression. Clin Chim.Acta 2001;312(1-2):213-219. PubMed
  5. Araghiniknam M, Chung S, Nelson-White T, and et al. Antioxidant activity of Dioscorea and dehydroepiandrosterone (DHEA) in older humans. Life Sciences 1996;59:L147-L157.
  6. Zeng M, Zhang L, Li M, et al. Estrogenic effects of the extracts from the Chinese Yam (Dioscorea opposite Thunb.) and its effective compounds in vitro and in vivo. Molecules. 2018 Jan 23;23(2). Pii: E11. PubMed
  7. Lu J, Wong RN, Zhang L, et al. Comparative analysis of proteins with stimulating activity on ovarian estradiol biosynthesis from four different Dioscorea species in vitro using both phenotypic and target-based approaches: implication for treating menopaus

See these in context on the Wild Yam monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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