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Dietary supplement

GABA 750 mg Maximum Strength Ingredients & Drug Interactions

by Swanson

GABA 750 mg Maximum Strength label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking GABA 750 mg Maximum Strength against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

GABA 750 mg Maximum Strength is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation.Based on those ingredients, 419 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gamma Aminobutyric Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against GABA 750 mg Maximum Strength by Swanson

Ask about any prescription or over-the-counter medication and we check it for interactions with GABA 750 mg Maximum Strength by Swanson — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of GABA 750 mg Maximum Strength by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: gamma-aminobutyric acid (GABA), a compound your brain naturally produces to help calm nerve activity. Each capsule delivers 750 mg.

The other ingredients are fillers and capsule materials — hypromellose, magnesium stearate, microcrystalline cellulose, and silica — that have no active role.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gamma-aminobutyric Acid (gaba)'s own graded uses on its monograph.

Why this rating?
  • The label markets this product for: promote relaxation and support restful sleep.
  • We looked for evidence on: Anxiety, Insomnia, Menopausal symptoms, stress, nervous tension, calmness.
  • The closest evidence on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Insomnia, Menopausal symptoms, Post-traumatic stress disorder (PTSD).

The evidence for GABA supplements isn't established in the data we hold. It's been studied for anxiety, ADHD, athletic performance, chronic bronchitis, and cerebral palsy, but the research so far isn't reliable enough to say whether it works for any of those uses.

If you're thinking about it for a specific condition, talk it over with your doctor to see if there's stronger evidence for what you're aiming for.

The evidence, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

GABA is generally well tolerated in the short term, but long-term safety hasn't been well studied — that's something to keep in mind if you're thinking about taking it regularly. The most common side effects reported with oral GABA are drowsiness, stomach upset, mild throat burning, muscle weakness, and nausea.

One study noted a case of temporary loss of menstruation when GABA was used alongside another supplement. There isn't enough safety information on file for pregnancy or breastfeeding — talk with your doctor or pharmacist before using it if you're pregnant, trying to conceive, or nursing.

Side effects, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gamma-aminobutyric Acid (gaba).
  • The most serious interaction on file is rated Moderate.
  • For scale: 419 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take blood pressure medications — GABA might lower your blood pressure further. Also double-check any sedating drugs, like sleep aids or pain relievers, since GABA could add to drowsiness, though it's unclear how big a concern that is in real life.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

GABA might be worth considering if you're looking for a calming supplement and have no blood pressure medications or sedating drugs on board. Because the long-term safety picture is unclear and evidence for its effectiveness is limited, it's worth discussing with your doctor or pharmacist before you start — especially if you take any prescription medications or have health conditions that need careful management.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about GABA 750 mg Maximum Strength, straight from the product label.

Brand Swanson
Barcode (UPC) 087614026763
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 308666
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for GABA 750 mg Maximum Strength by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
60
UPC/BARCODE
087614026763
IngredientAmount% DV
Gamma Aminobutyric Acid750 mg--

Other ingredients: Hypromellose, Magnesium Stearate, Microcrystalline Cellulose, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Swanson.com or call 1-800-437-4148

Science-Backed Quality Since 1969

Formulation

May help promote relaxation and ease nervous tension Supports restful, restorative sleep Promotes a feeling of calmness and relaxation

Sleep support Maximum strength

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one veggie capsule per day with water.

Precautions

Warning: For adults only. Keep out of reach of children.

Consult your physician before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

GABA 750mg per capsule

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

GABA 750 mg Maximum Strength by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

GABA 750 mg Maximum Strength label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in GABA 750 mg Maximum Strength by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Gamma Aminobutyric Acid

Interacts with
419 drugs
750 mg per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

Gamma Aminobutyric Acid monograph & interactions

Other (inactive) ingredients: Hypromellose, Magnesium Stearate, Microcrystalline Cellulose, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

GABA 750 mg Maximum Strength by Swanson Drug Interactions

Want to check YOUR meds against GABA 750 mg Maximum Strength?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
419Drugs
172 Moderate 247 Minor

Ingredients driving the most interactions

Gamma Aminobutyric Acid 419

Individual Drug Interactions

The ingredients in GABA 750 mg Maximum Strength interact with 419 drugs. Click any drug to see the details.

1 of the 1 ingredient in GABA 750 mg Maximum Strength interact with drugs. Each result below shows which ingredient is responsible. Gamma Aminobutyric Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in GABA 750 mg Maximum Strength with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Gamma Aminobutyric Acid2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
Gamma Aminobutyric Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for GABA 750 mg Maximum Strength, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

GABA 750 mg Maximum Strength by Swanson: Common Questions

Does GABA 750 mg Maximum Strength by Swanson interact with any medications?
Yes. Based on its ingredients, GABA 750 mg Maximum Strength has a known interaction with 419 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
GABA 750 mg Maximum Strength contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is GABA and why is it in this supplement?
GABA (gamma-aminobutyric acid) is a chemical your brain makes naturally to help calm nerve activity. The supplement form is meant to provide extra GABA, though how well it works when taken by mouth isn't well established.
Will this make me drowsy?
Drowsiness is the most commonly reported side effect with oral GABA. If it does happen, it's usually mild, but you should avoid driving or operating machinery until you know how you respond.
Is this safe to take long-term?
While GABA seems well tolerated in the short term, long-term safety hasn't been studied thoroughly. If you're planning to take it regularly, talk with your doctor or pharmacist first.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety information on file for pregnancy or breastfeeding. Talk with your doctor or pharmacist for personalized advice before using it.
Will this help with anxiety?
GABA has been studied for anxiety, but the evidence so far isn't reliable enough to say whether it works. Ask your doctor or pharmacist whether it's a good fit for what you're dealing with.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if GABA 750 mg Maximum Strength is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

GABA 750 mg Maximum Strength label
Go deeper

The Full Monographs Behind GABA 750 mg Maximum Strength’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gamma-aminobutyric Acid (gaba)

Interacts with 419 drugs

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...

Read the full Gamma-aminobutyric Acid (gaba) monograph →
Sources

Sources & How We Checked

GABA 750 mg Maximum Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gamma-aminobutyric Acid (gaba) 12 references
  1. Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
  2. Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
  3. Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
  4. Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
  5. Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
  6. ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
  7. Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
  8. Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
  9. Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
  10. Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
  11. Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
  12. de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed

See these in context on the Gamma-aminobutyric Acid (gaba) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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