Gas & Bloating Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Gas & Bloating against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Gas & Bloating is a dietary supplement by Gaia Herbs RapidRelief with 3 active ingredients. Its ingredients are commonly taken for poisoning and drug overdose (in emergency care), gas and bloating, upset stomach.Based on those ingredients, 2,094 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vegetable Charcoal, Fennel. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Gas & Bloating by Gaia Herbs RapidRelief
Ask about any prescription or over-the-counter medication and we check it for interactions with Gas & Bloating by Gaia Herbs RapidRelief — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Gas & Bloating by Gaia Herbs RapidRelief
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 3 of its 3 active ingredients.
- No proprietary blends here — you can verify the dose of every single component.
At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.
Why this rating?
- 2 of the 2 matched ingredients can interact with medications — Activated Charcoal, Fennel.
- The most serious interaction on file is rated Major.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
- For scale: 2,095 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 2 of 2.
- General safety write-ups exist for 2 of 2.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Gas & Bloating, straight from the product label.
| Brand | Gaia Herbs RapidRelief |
|---|---|
| Net contents | 50 Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Oct 26, 2011 |
| DSLD ID | 633 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Gas & Bloating by Gaia Herbs RapidRelief, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Vegetable Charcoal | 242 mg | -- |
| Fennel | 162 mg | -- |
| Proprietary Blend | 404 mg | -- |
Other ingredients: Vegetable Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
DIETARY SUPPLEMENT
Precautions
Notice: Vegetable charcoal may interfere with the absorption of drugs. Not to be used during pregnancy or lactation. If you have a medical condition or take pharmaceutical drugs, please consult with your doctor before use. Keep away from children. Use only as directed on label.
General Statements
ETUSGABL00PX-B [02]1013-0610
meetyourherbs(TM)
meetyourherbs(TM) ID# 00071024
Suggested/Recommended/Usage/Directions
Suggested Use Adults take two capsules as needed for occasional use, or as directed by a qualified health care professional.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Gas & Bloating by Gaia Herbs RapidRelief label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Gas & Bloating by Gaia Herbs RapidRelief
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container25 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Vegetable Charcoal
Interacts with2,027 drugs
Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some poisonings...
Vegetable Charcoal monograph & interactionsFennel
Interacts with740 drugs
Fennel is a Mediterranean herb widely used as a food and spice, and traditionally taken for digestive complaints, colic, and menstrual cramps. Some sm...
Fennel monograph & interactionsProprietary Blend
Other (inactive) ingredients: Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.
Gas & Bloating by Gaia Herbs RapidRelief Drug Interactions
Gas & Bloating contains 3 ingredients, and 2 of them have known drug interactions. Altogether they interact with 2,094 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Gas & Bloating?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Gas & Bloating interact with 2,094 drugs. Click any drug to see the details.
2 of the 3 ingredients in Gas & Bloating interact with drugs. Each result below shows which ingredient is responsible. Vegetable Charcoal Fennel
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Abciximab interactionFennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Abemaciclib interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Abiraterone interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Abiraterone Acetate interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Abrocitinib interactionFennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acalabrutinib interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acenocoumarol interactionFennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Aspirin interactionFennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Aspirin, Caffeine interactionFennelAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Butalbital, Caffeine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Butalbital, Caffeine, Codeine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Gas & Bloating — through 1 ingredient. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Caffeine, Codeine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Caffeine, Codeine, Salicylamide interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Caffeine, Dihydrocodeine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Gas & Bloating — through 2 ingredients. Tap an ingredient for the detail:
Vegetable CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Vegetable Charcoal + Acetaminophen, Caffeine, Isometheptene interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Gas & Bloating with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Vegetable Charcoal
Oral Drugs
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Activated charcoal adsorbs various drugs and may reduce their absorption and/or half-life. Examples of affected drugs include acetaminophen, aminophylline, amiodarone, atenolol, carbamazepine, dapsone, digoxin, disopyramide, fluoxetine, indomethacin, moxifloxacin, nadolol, phenytoin, phenobarbital, piroxicam, quinine, sotalol, theophylline, tricyclic antidepressants, valproate, and verapamil. Avoid co-administration, except after drug overdose.
Alcohol (Ethanol)
The binding action of activated charcoal may be reduced by alcohol.
Alcohol may lower the adsorptive capacity of activated charcoal.
Contraceptive Drugs
Activated charcoal may reduce the clinical effects of oral contraceptives.
Activated charcoal, taken in a dose of 5 grams four times daily for 3 days, may bind to, and reduce the absorption of, oral contraceptives, thereby limiting their effectiveness and increasing the risk of contraceptive failure. However, some clinical research shows that the risk for this interaction is minimal when activated charcoal is taken either 3 hours after or at least 12 hours before oral contraceptives.
Fennel
Anticoagulant/Antiplatelet Drugs
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Animal research suggests that fennel oil has antithrombotic and antiplatelet effects.
Ciprofloxacin (Cipro)
Theoretically, fennel might decrease the levels and clinical effects of ciprofloxacin.
Animal research shows that fennel reduces ciprofloxacin bioavailability by nearly 50%, possibly due to the metal cations such as calcium, iron, and magnesium contained in fennel. This study also found that fennel increased tissue distribution and slowed elimination of ciprofloxacin.
Contraceptive Drugs
Theoretically, taking large amounts of fennel might decrease the effects of contraceptive drugs due to competition for estrogen receptors.
Some constituents of fennel have estrogenic activity.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
In vitro research suggests that fennel inhibits CYP3A4 enzyme activity. This effect has not been reported in humans.
Estrogens
Theoretically, taking large amounts of fennel might interfere with hormone replacement therapy due to competition for estrogen receptors.
Some constituents of fennel have estrogenic activity.
Tamoxifen (Nolvadex)
Theoretically, taking large amounts of fennel might decrease the antiestrogenic effect of tamoxifen.
Some constituents of fennel have estrogenic activity, which may interfere with the antiestrogenic activity of tamoxifen.
Brand information
Manufacturer and brand details for Gas & Bloating, from the product label.
Gas & Bloating by Gaia Herbs RapidRelief: Common Questions
Does Gas & Bloating by Gaia Herbs RapidRelief interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Gas & Bloating is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Gas & Bloating’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Activated Charcoal
Interacts with 2,027 drugsActivated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some poisonings and overdoses. For everyday uses like g...
Read the full Activated Charcoal monograph → Herb & supplement monographFennel
Interacts with 740 drugsFennel is a Mediterranean herb widely used as a food and spice, and traditionally taken for digestive complaints, colic, and menstrual cramps. Some small studies suggest possible benefit for...
Read the full Fennel monograph →Sources & How We Checked
Gas & Bloating's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 31 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Activated Charcoal 14 references
- Kaaja RJ, Kontula KK, Raiha A, Laatikainen T. Treatment of cholestasis of pregnancy with peroral activated charcoal. A preliminary study. Scand J Gastroenterol 1994;29:178-81.
- Anon. Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. J Toxicol Clin T
- Park GD, Spector R, Kitt TM. Superactivated charcoal versus cholestyramine for cholesterol lowering: a randomized cross-over trial. J Clin Pharmacol 1988;28:416-9. PubMed
- Hoegberg LC, Angelo HR, Christophersen AB, Christensen HR. Effect of ethanol and pH on the adsorption of acetaminophen (paracetamol) to high surface activated charcoal, in vitro studies. J Toxicol Clin Toxicol 2002;40:59-67. PubMed
- Brahmi N, Kouraichi N, Thabet H, Amamou M. Influence of activated charcoal on the pharmacokinetics and the clinical features of carbamazepine poisoning. Am J Emerg Med 2006;24(4):440-3. PubMed
- Gude AB, Hoegberg LC, Angelo HR, Christensen HR. Dose-dependent adsorptive capacity of activated charcoal for gastrointestinal decontamination of a simulated paracetamol overdose in human volunteers. Basic Clin Pharmacol Toxicol 2010;106(5)406-10. PubMed
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