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Dietary supplement

Gotu Kola Alcohol-Free Ingredients & Drug Interactions

by Herb Pharm

Gotu Kola Alcohol-Free label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Gotu Kola Alcohol-Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Gotu Kola Alcohol-Free is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for wound healing, varicose veins and poor circulation, anxiety and stress.Based on those ingredients, 579 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gotu Kola Glycerite. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Gotu Kola Alcohol-Free by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Gotu Kola Alcohol-Free by Herb Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Gotu Kola Alcohol-Free by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: gotu kola glycerite, a liquid extract of the gotu kola plant. It's formulated without alcohol, using vegetable glycerine and distilled water as the base instead.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Gotu Kola's overall clinical evidence instead.

Moderate

Some clinical evidence supports Gotu Kola for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Burns — rated "Possibly Effective" (Natural Medicines).
  • On file: Venous insufficiency — rated "Possibly Effective" (Natural Medicines).

Gotu kola is possibly effective for venous insufficiency (poor blood flow in veins) and burns. Evidence for radiation dermatitis, cognitive function, and Alzheimer's disease is either insufficient or points to it being ineffective.

There isn't enough reliable evidence yet to know whether it helps with generalized anxiety.

The evidence, ingredient by ingredient Gotu Kola

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gotu kola is generally well tolerated in the short term, though quality evidence is limited. The most common side effects are stomach irritation and nausea.

There's also a rare concern about liver toxicity; while four case reports exist, it's unclear whether gotu kola was responsible, and one trial of 120 mg daily for 6 months showed no liver function changes. The safety data advises against using gotu kola during pregnancy.

Safety during breastfeeding is unknown, so it's best avoided then too. Talk with your doctor or pharmacist about whether this product is appropriate for you if you're pregnant, nursing, or planning either.

Side effects, ingredient by ingredient Gotu Kola

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gotu Kola.
  • The most serious interaction on file is rated Moderate.
  • For scale: 580 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check your medications against CNS depressants (sedating drugs like antihistamines, some antidepressants, and benzodiazepines) and hepatotoxic drugs (liver-stressing medications). If either group applies to you, run them through the checker on this page or talk with your pharmacist first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Gotu Kola Alcohol-Free may be worth considering if you're looking at it for venous insufficiency or burns and you don't take CNS depressants or liver-stressing drugs. If you do take either of those medication types, or if you're pregnant or breastfeeding, check with your doctor or pharmacist before starting.

Altogether, these interactions span 580 individual medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Gotu Kola Alcohol-Free, straight from the product label.

Brand Herb Pharm
Barcode (UPC) 090700002879
Net contents 4 fl. Oz.; 118.4 mL
Market status On market
Date entered into DSLD Jul 25, 2013
DSLD ID 24006
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Gotu Kola Alcohol-Free by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
30 Drop(s)
Maximum serving Sizes:
40 Drop(s)
UPC/BARCODE
090700002879
IngredientAmount% DV
Gotu Kola Glycerite0 NP--

Other ingredients: Vegetable Glycerine, distilled Water, Gotu Kola extractives

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

We prepare our Gotu Kola Glycerite from the whole herb of Centella asiatica plants that are Certified Organically Grown without the use of chemical fertilizers, pesticides or herbicides. To assure thorough extraction of Gotu Kola's bioactive compounds, the plants are hand-harvested at their optimal potency, are carefully shade-dried, and are then thoroughly extracted.

HERBAL GLYCERITE EXTRACT

General

006

FDA Statement of Identity

HERBAL SUPPLEMENT

Suggested/Recommended/Usage/Directions

SUGGESTED USE Shake Well Before Using Two to four times per day take 30 to 40 drops in a little water.

Precautions

Keep Out of the Reach of Children

Formulation

CONTAINS NO ALCOHOL

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Gotu Kola Alcohol-Free by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Gotu Kola Alcohol-Free label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Gotu Kola Alcohol-Free by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size30 Drop(s) Dosage formLiquid Amounts shown are per serving.

Gotu Kola Glycerite

Interacts with
579 drugs
0 NP per serving

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporti...

Gotu Kola Glycerite monograph & interactions

Other (inactive) ingredients: Vegetable Glycerine, Distilled Water, Gotu Kola extractives. These complete the product’s ingredient list but are not active constituents.

Interaction report

Gotu Kola Alcohol-Free by Herb Pharm Drug Interactions

Want to check YOUR meds against Gotu Kola Alcohol-Free?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
579Drugs
579 Moderate

Ingredients driving the most interactions

Gotu Kola Glycerite 579

Individual Drug Interactions

The ingredients in Gotu Kola Alcohol-Free interact with 579 drugs. Click any drug to see the details.

1 of the 1 ingredient in Gotu Kola Alcohol-Free interact with drugs. Each result below shows which ingredient is responsible. Gotu Kola Glycerite

Each ingredient & the kinds of drugs it affects

For each ingredient in Gotu Kola Alcohol-Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Gotu Kola Glycerite2 drug types · 579 drugs

Cns Depressants

Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.

Likelihood Possible Evidence D
Gotu Kola Glycerite full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Gotu Kola Alcohol-Free, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Gotu Kola Alcohol-Free by Herb Pharm: Common Questions

Does Gotu Kola Alcohol-Free by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Gotu Kola Alcohol-Free has a known interaction with 579 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Gotu Kola Alcohol-Free contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is gotu kola, and what is it used for?
Gotu kola is a plant traditionally used in herbal medicine. In this product, it's possibly effective for venous insufficiency (sluggish blood flow in veins) and burns. Evidence doesn't support it yet for cognitive function or Alzheimer's disease.
Will this make me drowsy?
Lab research suggests gotu kola may have sedative effects through how it interacts with calming receptors in the brain. If you already take medications that make you drowsy (like sleep aids or certain antihistamines), this could add to that effect — check with your pharmacist first.
Are there concerns about liver damage?
There's a theoretical concern, and four case reports exist, but it's unclear whether gotu kola was actually the cause in those cases. One clinical trial tracking liver health found no problems in people taking 120 mg daily for 6 months. Still, it's something to keep in mind, especially if you take other drugs that stress the liver.
Is it safe during pregnancy?
The safety data advises against using gotu kola during pregnancy because there isn't enough evidence to be sure. Talk with your doctor or pharmacist if you're pregnant or planning to be.
What are the side effects?
Most commonly, stomach irritation and nausea. These are mild and seem to be the main concerns with regular use. Liver toxicity is rare but has been reported, so short-term use is generally safer than long-term.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Gotu Kola Alcohol-Free is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Gotu Kola Alcohol-Free label
Go deeper

The Full Monographs Behind Gotu Kola Alcohol-Free’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gotu Kola

Interacts with 579 drugs

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...

Read the full Gotu Kola monograph →
Sources

Sources & How We Checked

Gotu Kola Alcohol-Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gotu Kola 18 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiol 1987;38:46-50. PubMed
  3. Brinkhaus B, Lindner M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the east Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.
  4. Eun HC, Lee AY. Contact dermatitis due to madecassol. Contact Dermatitis 1985;13:310-3.. PubMed
  5. Hausen BM. Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer. Contact Dermatitis 1993;29:175-9..
  6. Bilbao I, Aguirre A, Zabala R, et al. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33:435-6.
  7. Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52 Suppl 2 DOI
  8. Bradwejn J, Zhou Y, Koszycki D, Shlik J. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20:680-4. PubMed
  9. Young GL, Jewell D. Creams for preventing stretch marks in pregnancy. Cochrane Database Syst Rev 2000;(2):CD000066. PubMed
  10. Jorge OA, Jorge AD. Hepatotoxicity associated with the ingestion of Centella asiatica. Rev Esp Enferm Dig 2005;97:115-24. PubMed
  11. Mallol J, Belda MA, Costa D, et al. Prophylaxis of striae gravidarum with a topical formulation. A double blind trial. Int J Cosmet Sci 1991;3:51-7.
  12. Izu, R., Aguirre, A., Gil, N., and Diaz-Perez, J. L. Allergic contact dermatitis from a cream containing Centella asiatica extract. Contact Dermatitis 1992;26(3):192-193.
  13. Santucci, B., Picardo, M., and Cristaudo, A. Contact dermatitis due to Centelase. Contact Dermatitis 1985;13(1):39. PubMed
  14. Vena, G. A. and Angelini, G. Contact allergy to Centelase. Contact Dermatitis 1986;15(2):108-109. PubMed
  15. Marastoni, F., Baldo, A., Redaelli, G., and Ghiringhelli, L. [Centella asiatica extract in venous pathology of the lower limbs and its evaluation as compared with tribenoside]. Minerva Cardioangiol. 1982;30(4):201-207.
  16. Danese, P., Carnevali, C., and Bertazzoni, M. G. Allergic contact dermatitis due to Centella asiatica extract. Contact Dermatitis 1994;31(3):201.
  17. Bilbao, I., Aguirre, A., Zabala, R., Gonzalez, R., Raton, J., and Diaz Perez, J. L. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33(6):435-436.
  18. Dantuluri S, North-lewis P, Karthik SV. Gotu Kola induced hepatotoxicity in a child - need for caution with alternative remedies. Dig Liver Dis. 2011;43(6):500. PubMed

See these in context on the Gotu Kola monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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