Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Gotu Kola Alcohol Free Ingredients & Drug Interactions

by Herbal Terra

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Gotu Kola Alcohol Free is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for wound healing, varicose veins and poor circulation, anxiety and stress.Based on those ingredients, 579 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gotu Kola Leaf Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Gotu Kola Alcohol Free by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: gotu kola leaf extract (dry form). Gotu kola is a plant traditionally used in herbal medicine.

The liquid also includes two inactive ingredients — glycerin and water — which serve as the base and help preserve the extract.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Gotu Kola's overall clinical evidence instead.

Moderate

Some clinical evidence supports Gotu Kola for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Burns — rated "Possibly Effective" (Natural Medicines).
  • On file: Venous insufficiency — rated "Possibly Effective" (Natural Medicines).

Gotu kola is possibly effective for venous insufficiency (poor blood flow in the veins) and possibly effective for burns. For radiation dermatitis (skin damage from radiation), the evidence suggests it's probably not effective.

For cognitive function and Alzheimer disease, there isn't enough reliable evidence to say whether it works. The same is true for generalized anxiety — we simply don't have solid data on its usefulness for that condition.

The evidence, ingredient by ingredient Gotu Kola

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, gotu kola is generally well tolerated short-term, though quality evidence is limited. The most common side effects are stomach irritation and nausea.

Rarely, liver toxicity has been reported — there are at least four case reports — but lab analysis of those products wasn't done, so contaminants weren't ruled out, and doses weren't recorded. In one clinical trial where liver function was monitored, taking 120 mg daily for 6 months didn't cause liver function changes.

Gotu kola is traditionally avoided in pregnancy because there isn't enough safety data. It should also be avoided during breastfeeding, as safety is unknown.

Side effects, ingredient by ingredient Gotu Kola

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gotu Kola.
  • The most serious interaction on file is rated Moderate.
  • For scale: 580 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this product if you take CNS depressants (sedatives, sleep aids, anxiety medications) — gotu kola may increase drowsiness (Moderate severity). Also double-check if you're on any hepatotoxic drugs (medications that stress the liver), since gotu kola might add to that effect (Moderate severity).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Gotu Kola Alcohol Free may help with venous insufficiency or burns. You should be cautious if you take CNS depressants (sedatives, sleep aids) or medications that affect the liver — check with your pharmacist first.

Avoid it if you're pregnant or breastfeeding, and don't use it long-term without talking to your doctor about liver monitoring.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Gotu Kola Alcohol Free, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7386005180996
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 324216
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Gotu Kola Alcohol Free by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
7386005180996
IngredientAmount% DV
Gotu Kola Leaf Extract, Dry1156 mg--

Other ingredients: Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.

Precautions

We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!

Do not use if you are allergic to any ingredients.

Storage

Store in a cool, dry, dark place.

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

Formulation

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Sugar free

Expertly extracted 100% natural Premium product

No alcohol (ethyl), artificial ingredients, color additives, fillers or binders.

Natural Gluten free

Formula

Centella asiatica

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA

See for yourself

Gotu Kola Alcohol Free by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Gotu Kola Alcohol Free by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Gotu Kola Leaf Extract, Dry

Interacts with
579 drugs
1156 mg per serving

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporti...

Gotu Kola Leaf Extract, Dry monograph & interactions

Other (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Gotu Kola Alcohol Free by Herbal Terra Drug Interactions

Want to check YOUR meds against Gotu Kola Alcohol Free?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
579Drugs
579 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Gotu Kola Alcohol Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Gotu Kola Leaf Extract, Dry2 drug types · 579 drugs

Cns Depressants

Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Gotu Kola Alcohol Free, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra LLC
Phone Number
+18083857868
Web Address
herbalterra.com
Pharmacist Counseling Corner

Gotu Kola Alcohol Free by Herbal Terra: Common Questions

Does Gotu Kola Alcohol Free by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Gotu Kola Alcohol Free has a known interaction with 579 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Gotu Kola Alcohol Free contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a sleep aid or anti-anxiety medication?
You should check with your pharmacist first. Gotu kola may boost the sedative effects of these drugs, which could make you more drowsy or impaired. Don't start it without confirming it's safe with your specific medications.
Is gotu kola hard on the liver?
There are at least four case reports of liver injury linked to gotu kola, but it's unclear whether gotu kola was the cause — the products weren't tested for contaminants, and doses weren't recorded. In a clinical trial where liver function was watched, 120 mg daily for 6 months caused no liver function changes. If you have liver concerns or take liver-stressing medications, talk to your doctor before using it.
What's this good for?
Gotu kola is possibly effective for venous insufficiency (poor blood flow in the veins) and possibly effective for burns. For other uses like cognitive function, Alzheimer disease, or anxiety, there isn't enough evidence to say whether it works.
What are the common side effects?
Most people tolerate it well short-term. The most common side effects are stomach irritation and nausea. Liver toxicity is rare but has been reported, though the cause in those cases isn't certain.
Can I use this if I'm pregnant or breastfeeding?
No — gotu kola is traditionally avoided in pregnancy because there isn't enough safety data, and it should be avoided during breastfeeding as well. Talk to your doctor or pharmacist about alternatives if you need herbal support during this time.
How does this come — is it alcohol-free really?
Yes, this Herbal Terra product is a liquid extract made with glycerin and water, not alcohol. It's a good option if you need to avoid alcohol for health or personal reasons.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Gotu Kola Alcohol Free is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Gotu Kola Alcohol Free label
Go deeper

The Full Monographs Behind Gotu Kola Alcohol Free’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Gotu Kola Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gotu Kola 18 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiol 1987;38:46-50. PubMed
  3. Brinkhaus B, Lindner M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the east Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.
  4. Eun HC, Lee AY. Contact dermatitis due to madecassol. Contact Dermatitis 1985;13:310-3.. PubMed
  5. Hausen BM. Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer. Contact Dermatitis 1993;29:175-9..
  6. Bilbao I, Aguirre A, Zabala R, et al. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33:435-6.
  7. Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52 Suppl 2 DOI
  8. Bradwejn J, Zhou Y, Koszycki D, Shlik J. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20:680-4. PubMed
  9. Young GL, Jewell D. Creams for preventing stretch marks in pregnancy. Cochrane Database Syst Rev 2000;(2):CD000066. PubMed
  10. Jorge OA, Jorge AD. Hepatotoxicity associated with the ingestion of Centella asiatica. Rev Esp Enferm Dig 2005;97:115-24. PubMed
  11. Mallol J, Belda MA, Costa D, et al. Prophylaxis of striae gravidarum with a topical formulation. A double blind trial. Int J Cosmet Sci 1991;3:51-7.
  12. Izu, R., Aguirre, A., Gil, N., and Diaz-Perez, J. L. Allergic contact dermatitis from a cream containing Centella asiatica extract. Contact Dermatitis 1992;26(3):192-193.
  13. Santucci, B., Picardo, M., and Cristaudo, A. Contact dermatitis due to Centelase. Contact Dermatitis 1985;13(1):39. PubMed
  14. Vena, G. A. and Angelini, G. Contact allergy to Centelase. Contact Dermatitis 1986;15(2):108-109. PubMed
  15. Marastoni, F., Baldo, A., Redaelli, G., and Ghiringhelli, L. [Centella asiatica extract in venous pathology of the lower limbs and its evaluation as compared with tribenoside]. Minerva Cardioangiol. 1982;30(4):201-207.
  16. Danese, P., Carnevali, C., and Bertazzoni, M. G. Allergic contact dermatitis due to Centella asiatica extract. Contact Dermatitis 1994;31(3):201.
  17. Bilbao, I., Aguirre, A., Zabala, R., Gonzalez, R., Raton, J., and Diaz Perez, J. L. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33(6):435-436.
  18. Dantuluri S, North-lewis P, Karthik SV. Gotu Kola induced hepatotoxicity in a child - need for caution with alternative remedies. Dig Liver Dis. 2011;43(6):500. PubMed

See these in context on the Gotu Kola monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring