Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Grass Fed Beef Liver 3,000 mg Ingredients & Drug Interactions

by Dr. Mercola

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Grass Fed Beef Liver 3,000 mg is a dietary supplement by Dr. Mercola with 2 active ingredients. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Bovine Liver. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Grass Fed Beef Liver 3,000 mg by Dr. Mercola

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bovine liver (grass-fed beef liver) at 3,000 mg per serving. Bovine liver is a nutrient-dense organ supplement that naturally delivers vitamin A, iron, and other nutrients found in animal liver tissue.

The capsule also contains several inactive ingredients — hydroxypropyl methylcellulose (the capsule material), rice husk, rice bran extract, gum acacia, and sunflower oil — which are fillers and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune support detoxification and blood flow.
  • We looked for evidence on: Hepatitis C, liver health, energy and fatigue.
  • The closest evidence on file: Liver Extract is rated "Insufficient Reliable Evidence To Rate" for Hepatitis C (Natural Medicines).

The evidence for liver extract in chronic fatigue syndrome (CFS) is rated as possibly ineffective in our data, meaning it's not likely to help with that condition. For hepatitis C, there isn't enough reliable evidence yet to say whether it works or doesn't.

If you're considering this product for a specific health concern, talk with your pharmacist or doctor about what the current evidence actually supports.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

No adverse reactions have been reported in the data we hold, but a thorough safety evaluation hasn't been done either. The bigger concerns are the high levels of vitamin A and iron that liver products can deliver — vitamin A in particular can harm a developing baby, so pregnancy is one time to avoid it unless your doctor says otherwise.

There's also a theoretical risk of contamination: liver is sourced from slaughterhouses and could come from sick or diseased animals, and in countries where bovine spongiform encephalitis (BSE, or mad cow disease) has been found, there's a risk of contaminated tissue. No cases of BSE transfer to humans from liver extract have been reported, but the risk remains a reason to check where your product is sourced.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking this product if you use warfarin (Coumadin) — a blood thinner — or if you take iron supplements or iron-containing medications. The vitamin K in liver extract may reduce warfarin's effect, and the natural iron content could add up if you're already taking iron.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Grass-fed beef liver is generally well tolerated as a whole-food supplement for healthy adults who aren't taking blood thinners or iron supplements. If you're on warfarin or iron medication, or if you're pregnant, check with your pharmacist first.

Ask where the product is sourced — ideally from countries without a history of BSE.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Grass Fed Beef Liver 3,000 mg, straight from the product label.

Brand Dr. Mercola
Barcode (UPC) 810094213046
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 327167
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Grass Fed Beef Liver 3,000 mg by Dr. Mercola, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
30
UPC/BARCODE
810094213046
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Total Sugars0 Gram(s)--
Total Fat0.5 Gram(s)1%
Protein2 Gram(s)--
Bovine Liver3000 mg--

Other ingredients: Hydroxypropyl Methylcellulose, Rice Husk, Rice Bran Extract, Gum Acacia, Sunflower Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Adults, as a dietary supplement, take six (6) capsules daily.

Precautions

Keep out of reach of children.

Do not use if safety seal is broken.

If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Immune support Detoxification support Blood flow support

Formula

Grass Fed Beef Liver 3,000 mg per serving

FDA Statement of Identity

Dietary Supplement

General Statements

Providing quality products since 2001.

See for yourself

Grass Fed Beef Liver 3,000 mg by Dr. Mercola label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Grass Fed Beef Liver 3,000 mg by Dr. Mercola

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size6 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

2 Gram(s) per serving

Bovine Liver

Interacts with
3 drugs
3000 mg per serving

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Bovine Liver monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Rice Husk, Rice Bran Extract, Gum Acacia, Sunflower Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Grass Fed Beef Liver 3,000 mg by Dr. Mercola Drug Interactions

Want to check YOUR meds against Grass Fed Beef Liver 3,000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Grass Fed Beef Liver 3,000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bovine Liver2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
The maker

Brand information

Manufacturer and brand details for Grass Fed Beef Liver 3,000 mg, from the product label.

Dr. Mercola

See all Dr. Mercola products
Name
NHP
Street Address
125 SW 3rd Place
City
Cape Coral
State
FL
ZipCode
33991
Phone Number
(877) 985-2696
Pharmacist Counseling Corner

Grass Fed Beef Liver 3,000 mg by Dr. Mercola: Common Questions

Does Grass Fed Beef Liver 3,000 mg by Dr. Mercola interact with any medications?
Yes. Based on its ingredients, Grass Fed Beef Liver 3,000 mg has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Grass Fed Beef Liver 3,000 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product have any side effects?
No adverse reactions have been reported so far. However, a full safety evaluation hasn't been done, so we can't rule them out completely. At the doses in this product, the main concern is the high vitamin A and iron content — both can cause problems if you get too much over time.
Is it safe to take if I'm pregnant?
Liver products contain very high vitamin A, which can harm a developing baby. The safety data advises against using this product unless your doctor specifically tells you it's okay. Talk with your doctor or pharmacist for personalized advice.
Is it safe to take if I'm breastfeeding?
The data we have doesn't cover safety during breastfeeding. There isn't enough information to know either way, so check with your doctor or pharmacist before using it while nursing.
Can this help with chronic fatigue?
The evidence suggests it's possibly ineffective for chronic fatigue syndrome (CFS), so it's not likely to help with that condition based on what we know.
What's the difference between grass-fed and regular beef liver supplements?
The product facts we have don't detail the nutritional differences between grass-fed and grain-fed sources. For that comparison, you'd want to check the manufacturer's full nutrition label or talk with a nutritionist.
Where is the liver sourced from?
The product facts don't specify the country of origin. Because of concerns about contamination from sick animals or BSE in certain countries, it's worth checking with the manufacturer or the label to confirm where the beef liver comes from.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Grass Fed Beef Liver 3,000 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Grass Fed Beef Liver 3,000 mg label
Go deeper

The Full Monographs Behind Grass Fed Beef Liver 3,000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Grass Fed Beef Liver 3,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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