Ubiquinol 100 mg Ingredients & Drug Interactions
by Dr. Mercola
What is this page for?
First and foremost: checking Ubiquinol 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Ubiquinol 100 mg is a dietary supplement by Dr. Mercola with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Q+, Kaneka Ubiquinol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Ubiquinol 100 mg by Dr. Mercola
Ask about any prescription or over-the-counter medication and we check it for interactions with Ubiquinol 100 mg by Dr. Mercola — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Ubiquinol 100 mg by Dr. Mercola
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Q+ Kaneka Ubiquinol, a form of coenzyme Q10 (also called CoQ10), at 100 mg per capsule. CoQ10 is a natural compound your body makes and uses for energy production in your cells.
The capsule also contains inactive ingredients — medium chain triglyceride, D-limonene, and fish gelatin — which help deliver and stabilize the active ingredient.
Does it work?
Strong evidence
Coenzyme Q10 is likely effective for treating coenzyme Q10 deficiency. It's possibly effective for fibromyalgia, migraine headaches, congestive heart failure, and diabetic neuropathy (nerve damage from diabetes).
If you're taking this for one of those conditions, talk with your doctor or pharmacist about whether the evidence supports it for your specific situation.
How safe is it?
Well-documented data
Orally, coenzyme Q10 is generally well tolerated by most adults. In clinical studies, no serious side effects have been reported.
The most common complaints are gastrointestinal — appetite suppression, diarrhea, upset stomach, heartburn, nausea, and vomiting — though these occur in less than 1% of people. Headache, dizziness, and insomnia have also been reported, along with rare reports of trembling or lethargy.
A small number of people have reported skin itching or allergic rash. Safety data during pregnancy is not available; if you're pregnant, there isn't enough information to know either way, so check with your doctor.
Breastfeeding safety hasn't been well studied either — use caution and confirm with your doctor.
Meds to double-check
Moderate interaction found
Before you start, double-check with your pharmacist if you take warfarin or other blood thinners — coenzyme Q10 may reduce their effectiveness. Chemotherapy drugs, especially alkylating agents like cyclophosphamide, are another category to verify.
Blood pressure medications deserve a quick review too, since CoQ10 might add to their effect.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Ubiquinol is a solid choice if you're deficient in CoQ10 or exploring it for heart health, migraines, or fibromyalgia. If you take warfarin, chemotherapy, or blood pressure medications, you'll want to check with your pharmacist first — this supplement can interfere with how those work.
Generally well tolerated, but stop and tell us if you get stomach upset or skin itching.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Ubiquinol 100 mg, straight from the product label.
| Brand | Dr. Mercola |
|---|---|
| Barcode (UPC) | 813006011631 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 327649 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Ubiquinol 100 mg by Dr. Mercola, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Q+, Kaneka Ubiquinol | 100 mg | -- |
Other ingredients: Medium Chain Triglyceride, D-Limonene, Fish Gelatin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: Adults, as a dietary supplement, take one (1) capsule daily with a meal.
Precautions
Keep out of reach of children.
Do not use if safety seal is broken.
If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.
Contains Fish (Tilapia).
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
Mitochondrial health Energy production Enhanced bioavailability
Formula
Ubiquinol 100 mg per capsule
Made with Quality Q+ Kaneka Ubiquinol
FDA Statement of Identity
Dietary Supplement
General Statements
Providing quality products since 2001.
Brand IP Statement(s)
Q+, Kaneka Ubiquinol, and the quality seal are registered or pending trademarks of Kaneka Corp.
Seals/Symbols
Made with Quality Q+ Kaneka Ubiquinol
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Ubiquinol 100 mg by Dr. Mercola label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Ubiquinol 100 mg by Dr. Mercola
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Q+, Kaneka Ubiquinol
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Q+, Kaneka Ubiquinol monograph & interactionsOther (inactive) ingredients: Medium Chain Triglyceride, D-Limonene, Fish Gelatin. These complete the product’s ingredient list but are not active constituents.
Ubiquinol 100 mg by Dr. Mercola Drug Interactions
HelloPharmacist Interaction Report
Ubiquinol 100 mg by Dr.
Mercola can interact with several medication types. The most serious concern is chemotherapy drugs called alkylating agents — coenzyme Q10's antioxidant effect may theoretically reduce how well these cancer medications work by protecting tumor cells from the oxidative stress these drugs rely on.
Read the full breakdown — every affected drug type, severity by severity
Warfarin (a blood thinner) is another moderate-severity interaction: coenzyme Q10 is chemically similar to vitamin K and may have blood-clotting effects that weaken warfarin's ability to prevent clots. Four cases of reduced warfarin effectiveness tied to coenzyme Q10 have been reported in the medical literature.
Blood pressure medications are a minor concern — coenzyme Q10 might add to their blood-pressure-lowering effect, though study results have been mixed. Altogether, these interactions span 196 individual medications.
Use the medication checker on this page to look up your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Ubiquinol 100 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Ubiquinol 100 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in Ubiquinol 100 mg interact with drugs. Each result below shows which ingredient is responsible. Q+, Kaneka Ubiquinol
AltretamineHexalen
How Altretamine interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Altretamine interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Bendamustine Hydrochloride interactionBusulfanBusulfex, Myleran
How Busulfan interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Cisplatin interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Cyclophosphamide interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Dacarbazine interactionEstramustine Phosphate SodiumEmcyt
How Estramustine Phosphate Sodium interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Estramustine Phosphate Sodium interactionIfosfamideIfex
How Ifosfamide interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Ifosfamide interactionLomustineCeenu
How Lomustine interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Lomustine interactionLurbinectedinZepzelca
How Lurbinectedin interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Lurbinectedin interactionMechlorethamine HydrochlorideValchlor
How Mechlorethamine Hydrochloride interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Mechlorethamine Hydrochloride interactionMelphalanAlkeran, Hepzato
How Melphalan interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Melphalan interactionMelphalan FlufenamidePepaxto
How Melphalan Flufenamide interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Melphalan Flufenamide interactionMelphalan HydrochlorideEvomela
How Melphalan Hydrochloride interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Melphalan Hydrochloride interactionOxaliplatinEloxatin
How Oxaliplatin interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Oxaliplatin interactionProcarbazineMatulane
How Procarbazine interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Procarbazine interactionStreptozocinZanosar
How Streptozocin interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Streptozocin interactionTemozolomideTemodar
How Temozolomide interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Temozolomide interactionThiotepaTepadina, Thioplex
How Thiotepa interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Thiotepa interactionTrabectedinYondelis
How Trabectedin interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Q+, Kaneka Ubiquinol + Trabectedin interactionWarfarinWarfarin
How Warfarin interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolWarfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Q+, Kaneka Ubiquinol + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolWarfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Q+, Kaneka Ubiquinol + Warfarin Sodium interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Q+, Kaneka Ubiquinol + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Q+, Kaneka Ubiquinol + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Q+, Kaneka Ubiquinol + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Ubiquinol 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Q+, Kaneka UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Q+, Kaneka Ubiquinol + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Ubiquinol 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Q+, Kaneka Ubiquinol
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for Ubiquinol 100 mg, from the product label.
Dr. Mercola
See all Dr. Mercola products- Name
- NHP
- Street Address
- 125 SW 3rd Place
- City
- Cape Coral
- State
- FL
- ZipCode
- 33991
- Phone Number
- (877) 985-2696
Ubiquinol 100 mg by Dr. Mercola: Common Questions
Does Ubiquinol 100 mg by Dr. Mercola interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is ubiquinol, and how is it different from regular CoQ10?
Can I take this if I'm pregnant?
Is coenzyme Q10 safe while breastfeeding?
What side effects should I watch for?
Does this work for heart health?
If I take doses above 100 mg, should I split them?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Ubiquinol 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Ubiquinol 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Ubiquinol 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
- Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
- Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
- Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
- Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
- Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
- Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed
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