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Dietary supplement

Biothin Ketone Energy Ingredients & Drug Interactions

by Dr. Mercola

Biothin Ketone Energy label
See full label image
Liquid Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Biothin Ketone Energy against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Biothin Ketone Energy is a dietary supplement by Dr. Mercola with 1 active ingredient. Its ingredients are commonly taken for candida and yeast overgrowth, gut health support, antimicrobial.Based on those ingredients, 262 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Caprylic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Biothin Ketone Energy by Dr. Mercola

Ask about any prescription or over-the-counter medication and we check it for interactions with Biothin Ketone Energy by Dr. Mercola — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Biothin Ketone Energy by Dr. Mercola

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.

Biothin Ketone Energy is a liquid supplement with three active ingredients. Two of them — polyunsaturated fat and monounsaturated fat — are types of fat intended to support ketone energy.

The third is caprylic acid, a medium-chain saturated fatty acid that's also marketed for ketone support. The product contains no listed inactive ingredients (fillers or binders).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support metabolic health and energy production.
  • We looked for evidence on: Energy metabolism, Ketone metabolism, Mitochondrial function.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence we have on caprylic acid doesn't support its use for epilepsy or essential tremor — the data is too scarce to rate it. No effectiveness information is available for the product as a whole or for its role in "ketone energy." If you're considering this for a specific health goal, talk with us or your doctor — we can help you figure out whether there's solid evidence behind it.

The evidence, ingredient by ingredient Caprylic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Caprylic acid is generally recognized as safe in food amounts, but supplement doses haven't been studied much, so we'd recommend checking with your doctor before using this product. Short-term oral use appears well tolerated in most people.

A small number of users have reported mild abdominal discomfort or changes in taste; rarely, mild dizziness, headache, or fatigue. We don't have enough safety data for pregnancy or breastfeeding — even though caprylic acid occurs naturally in breast milk, concentrated supplement levels aren't well studied.

If you're pregnant or breastfeeding, talk with your doctor before taking this.

Side effects, ingredient by ingredient Caprylic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Caprylic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 262 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check with your pharmacist if you're on a blood thinner like warfarin, a blood pressure medication, or an NSAID (pain reliever such as ibuprofen or naproxen). Caprylic acid has documented Moderate interactions with all three types.

These are lab findings and haven't been seen in patients yet, but they're worth verifying against your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Biothin Ketone Energy is aimed at people seeking ketone support, but the evidence for its ingredients isn't strong. More important: if you take a blood thinner, blood pressure medication, or NSAID, you need to check with your pharmacist before starting it.

Caprylic acid may raise levels of those drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Biothin Ketone Energy, straight from the product label.

Brand Dr. Mercola
Barcode (UPC) 813006018142
Net contents 16 Fluid Ounce(s); 1 Pint(s); 473 mL
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 327148
Product type Fat/fatty Acid
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Biothin Ketone Energy by Dr. Mercola, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 mL
Maximum serving Sizes:
15 mL
Servings per container
31
UPC/BARCODE
813006018142
IngredientAmount% DV
Calories100 Calorie(s)--
Cholesterol0 mg--
Total Fat14 Gram(s)18%
Saturated Fat14 Gram(s)70%
Trans Fat0 Gram(s)--
Polyunsaturated Fat0 Gram(s)--
Monounsaturated Fat0 Gram(s)--
Caprylic Acid14 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Adults, as a dietary supplement, take one (1) tablespoon daily to support metabolic health. Ketone Energy may be taken directly, mixed into smoothies, teas or coffee, or added to cold dishes, such as yogurt or salads.

Precautions

Not recommended for cooking.

Keep out of reach of children.

Do not use if safety seal is broken.

If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.

Storage

No refrigeration required.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Metabolic health Energy production

Soy free GMO free Gluten free

Formula

Keto-approved

95% caprylic acid (C8) MCT oil

FDA Statement of Identity

Dietary Supplement

General Statements

Providing quality products since 2001.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Biothin Ketone Energy by Dr. Mercola label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Biothin Ketone Energy label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Biothin Ketone Energy by Dr. Mercola

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size15 mL Dosage formLiquid Servings per container31 Amounts shown are per serving.

Caprylic Acid

Interacts with
262 drugs
14 Gram(s) per serving Form: Medium Chain Triglyceride

Caprylic acid is a medium-chain fatty acid found in coconut oil and palm kernel oil that is popularly used for yeast overgrowth and gut health. While...

Caprylic Acid monograph & interactions
Interaction report

Biothin Ketone Energy by Dr. Mercola Drug Interactions

Want to check YOUR meds against Biothin Ketone Energy?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
262Drugs
262 Moderate

Ingredients driving the most interactions

Caprylic Acid 262

Individual Drug Interactions

The ingredients in Biothin Ketone Energy interact with 262 drugs. Click any drug to see the details.

1 of the 1 ingredient in Biothin Ketone Energy interact with drugs. Each result below shows which ingredient is responsible. Caprylic Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in Biothin Ketone Energy with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Caprylic Acid3 drug types · 262 drugs

Antihypertensive Drugs

Theoretically, caprylic acid might increase the risk of hypotension when used with antihypertensive drugs.
Animal research suggests that caprylic acid might have positive inotropic effects, resulting in reduced arterial pressure and vascular resistance and increased cardiac output.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

Theoretically, caprylic acid might increase plasma concentrations of NSAIDs.
In vitro research suggests that caprylic acid might displace NSAIDs from binding sites on albumin. This effect has not been reported in humans.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, caprylic acid might increase plasma concentrations of warfarin.
In vitro research suggests that high doses of caprylic acid might displace warfarin from albumin binding sites. This effect has not been reported in humans.

Likelihood Possible Evidence D
Caprylic Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Biothin Ketone Energy, from the product label.

Dr. Mercola

See all Dr. Mercola products
Name
NHP
Street Address
125 SW 3rd Place
City
Cape Coral
State
FL
ZipCode
33991
Phone Number
(877) 985-2696
Pharmacist Counseling Corner

Biothin Ketone Energy by Dr. Mercola: Common Questions

Does Biothin Ketone Energy by Dr. Mercola interact with any medications?
Yes. Based on its ingredients, Biothin Ketone Energy has a known interaction with 262 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Biothin Ketone Energy contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's caprylic acid doing in here?
Caprylic acid is a medium-chain fatty acid marketed in ketone supplements because it may be converted into ketones by your body. The product combines it with polyunsaturated and monounsaturated fats for the same purpose, though strong evidence for ketone energy benefits isn't documented in our data.
Is caprylic acid safe to use long-term?
Caprylic acid is generally recognized as safe in food, but supplement doses haven't been well studied over the long haul. Short-term use seems well tolerated, though some people report mild abdominal discomfort or taste changes. If you're thinking about taking this regularly, check with your doctor first.
Can I take this if I'm pregnant or breastfeeding?
We don't have enough safety data for either pregnancy or breastfeeding. Even though caprylic acid naturally appears in breast milk, concentrated supplement levels haven't been studied enough. Talk with your doctor or pharmacist to decide whether it's right for you.
What side effects might I notice?
Most people tolerate caprylic acid well short-term. The most common side effects are mild abdominal discomfort and taste changes. Rarely, people report dizziness, headache, or fatigue. If any of these bother you, stop and let us know.
Does this actually work for energy?
We don't have evidence in our data to say whether this product boosts energy or ketone levels. If you're looking for that kind of support, we'd suggest checking with your doctor or pharmacist about whether it's worth trying.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Biothin Ketone Energy is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Biothin Ketone Energy label
Go deeper

The Full Monographs Behind Biothin Ketone Energy’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Caprylic Acid

Interacts with 262 drugs

Caprylic acid is a medium-chain fatty acid found in coconut oil and palm kernel oil that is popularly used for yeast overgrowth and gut health. While laboratory studies show it has antimicro...

Read the full Caprylic Acid monograph →
Sources

Sources & How We Checked

Biothin Ketone Energy's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Caprylic Acid 5 references
  1. Massolini G, Aubry AF, McGann A, Wainer IW. Determination of the magnitude and enantioselectivity of ligand binding to rat and rabbit serum albumins using immobilized-protein high performance liquid chromatography stationary phases. Biochem Pharmacol 1993 PubMed
  2. Kristev A, Mitkov D, Lukanov Y, Chapkynov P. The effect of octanoic fatty acid on the cardiovascular system of the guinea pig. Cor Vasa 1989;31(4):321-7.
  3. Hayball PF, Holman JW, Nation RL. Influence of octanoic acid on the reversible protein binding of ketorolac enantiomers to human serum albumin (HSA): comparative liquid chromatographic studies using a HSA chiral stationary phase. J Chromatogr B Biomed App PubMed
  4. Noctor TA, Wainer IW, Hage DS. Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by high-performance liquid affinity chromatography, on a human serum albumin-based stationary phase. J Chromatogr 1992;5 PubMed
  5. Voller B, Lines E, McCrossin G, et al. Dose-escalation study of octanoic acid in patients with essential tremor. J Clin Invest. 2016;126(4):1451-7. PubMed

See these in context on the Caprylic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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