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Dietary supplement

Guduchi Powder Ingredients & Drug Interactions

by Banyan Botanicals

Guduchi Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Guduchi Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Guduchi Powder is a dietary supplement by Banyan Botanicals with 1 active ingredient. Its ingredients are commonly taken for immune support, fever, blood sugar support.Based on those ingredients, 612 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Indian Tinospora. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Guduchi Powder by Banyan Botanicals

Ask about any prescription or over-the-counter medication and we check it for interactions with Guduchi Powder by Banyan Botanicals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Guduchi Powder by Banyan Botanicals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Guduchi Powder contains one active ingredient: Indian Tinospora (Tinospora cordifolia), an herb used traditionally in Ayurvedic medicine. There are no other active ingredients.

The product contains no listed inactive fillers or excipients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Tinospora Cordifolia's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune system support and liver kidney function.
  • We looked for evidence on: Allergic rhinitis (hay fever), immune function, liver support, kidney support.
  • The closest evidence on file: Tinospora Cordifolia is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).

The evidence we hold supports Tinospora cordifolia as possibly effective for type 2 diabetes, based on clinical research showing it can lower fasting blood glucose and improve glycated hemoglobin (a marker of long-term blood sugar control). For allergic rhinitis (hay fever), asthma, athletic performance, cancer, and hepatitis, there isn't enough reliable evidence in our data to rate whether it works.

The evidence, ingredient by ingredient Tinospora Cordifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When taken by mouth, Tinospora cordifolia is generally well tolerated. The most common side effects reported are headache and nasal pain.

However, liver injury is a rare but serious concern — case reports describe autoimmune hepatitis, acute hepatitis, and acute liver failure in about 49 patients after taking Tinospora cordifolia (alone or combined with other ingredients) for a median of 42 to 90 days, with 2 patients requiring transplant and 4 deaths. Because of this risk, it should be used carefully and under guidance.

The safety data advises against use in pregnancy. There isn't enough reliable information to know whether it's safe while breastfeeding, so it's best avoided during lactation as well.

Talk with your doctor or pharmacist about your individual situation before taking this product if you're pregnant, nursing, or planning to become pregnant.

Side effects, ingredient by ingredient Tinospora Cordifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tinospora Cordifolia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 612 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take blood-sugar-lowering drugs (antidiabetes medications), as the risk of low blood sugar (hypoglycemia) goes up. You should also verify any immunosuppressants you use, since Tinospora cordifolia may reduce their effectiveness.

Additionally, confirm medications metabolized by your liver through CYP2D6, CYP2C19, CYP1A2, or CYP2C9 pathways — your levels of these drugs might increase.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Guduchi Powder may be worth considering if you have type 2 diabetes and want a traditional supplement option — the evidence supports its use for blood sugar. However, if you take blood-sugar-lowering drugs, immune-suppressing medications, or drugs broken down by your liver, you need to clear this with your doctor or pharmacist first.

Anyone with liver concerns or a history of liver disease should be especially cautious and discuss it with their healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Guduchi Powder, straight from the product label.

Brand Banyan Botanicals
Barcode (UPC) 618192068922
Net contents 0.5 Pound(s); 227 Gram(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 305649
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Guduchi Powder by Banyan Botanicals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s)
Maximum serving Sizes:
0.5 Teaspoon(s)
Servings per container
252
UPC/BARCODE
618192068922
IngredientAmount% DV
Indian Tinospora0.5 Teaspoon(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

(Tinospora cordifolia) Organic ayurvedic herbs

The healthy promoting powers of guduchi (Tinospora cordifolia) were so respected by the authors of the ancient Ayurvedic texts that they called it "Amrita" of "Divine Nectar." A powerful nutritive tonic, guduchi is one of the best herbs for balancing vata and pitta. It has the unusual characteristics of being heating while simultaneously removing excess pitta from the body. This heat burns accumulated natural toxins purifying the liver, kidneys, joints, and blood. It also helps soothe the skin and promotes a clear, healthy complexion. As a rejuvenative, guduchi strengthens the tissues, bolsters immunity, and promotes vitality while calming the mind and supporting proper function of the nervous system.

Formulation

Supporting your ayurvedic lifestyle

Non GMO

Bolsters the immune system and promotes vitality Supports proper function of the liver and kidneys Promotes healthy elimination of natural toxins Promotes healthy skin and clear complexion

Certified Organic by: QAI

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

USDA Organic

Sustainably Sourced Fairly Traded

Suggested/Recommended/Usage/Directions

Suggested use: 1/4 to 1/2 teaspoon with warm water, once or twice daily, or as directed by your health practitioner.

Precautions

If you are pregnant, nursing, taking medications, or have a medical condition, please consult your health care practitioner prior to the use of this product.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Banyan Botanicals was founded in 1996 with the mission to help people achieve and maintain optimal health and well-being. As an ayurvedic lifestyle company, we specialize in products made from herbs that are organically grown, sustainably sourced, fairly traded, and made in the USA. Banyan is committed to providing exceptional customer service, inspiring educational content, and the highest quality Ayurvedic herbs that are safe, pure, and effective. Illuminate your path to well-being Get your free Ayurvedic profile at banyanbotanicals.com/illuminate

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See for yourself

Guduchi Powder by Banyan Botanicals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Guduchi Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Guduchi Powder by Banyan Botanicals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container252 Amounts shown are per serving.

Indian Tinospora

Interacts with
612 drugs
0.5 Teaspoon(s) per serving

Tinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat fevers. Ea...

Indian Tinospora monograph & interactions
Interaction report

Guduchi Powder by Banyan Botanicals Drug Interactions

Want to check YOUR meds against Guduchi Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
612Drugs
612 Moderate

Ingredients driving the most interactions

Indian Tinospora 612

Individual Drug Interactions

The ingredients in Guduchi Powder interact with 612 drugs. Click any drug to see the details.

1 of the 1 ingredient in Guduchi Powder interact with drugs. Each result below shows which ingredient is responsible. Indian Tinospora

Each ingredient & the kinds of drugs it affects

For each ingredient in Guduchi Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Indian Tinospora6 drug types · 612 drugs

Antidiabetes Drugs

Theoretically, Tinospora cordifolia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research in adults with type 2 diabetes shows that Tinospora cordifolia can reduce fasting blood glucose and glycated hemoglobin. Additionally, animal research shows that Tinospora cordifolia has hypoglycemic effects.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that Tinospora cordifolia extract inhibits CYP1A2 at high concentrations. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C19 at high concentrations. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C9.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C9. Animal research shows that Tinospora cordifolia extract 400 mg/kg twice daily for 14 days reduces the clearance and increases plasma levels of glyburide, a CYP2C9 substrate. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2D6 at high concentrations. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, Tinospora cordifolia might reduce the effectiveness of immunosuppressants.
In vitro and animal research shows that Tinospora cordifolia has immunostimulant effects.

Likelihood Possible Evidence D
Indian Tinospora full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Guduchi Powder, from the product label.

Banyan Botanicals

See all Banyan Botanicals products
Name
Banyan Botanicals
City
Albuquerque
State
NM
ZipCode
87113
Phone Number
1-800-953-6424
Web Address
banyanbotanicals.com
Pharmacist Counseling Corner

Guduchi Powder by Banyan Botanicals: Common Questions

Does Guduchi Powder by Banyan Botanicals interact with any medications?
Yes. Based on its ingredients, Guduchi Powder has a known interaction with 612 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Guduchi Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have diabetes and use blood-sugar-lowering medication?
Clinical research shows Tinospora cordifolia lowers blood glucose on its own, so combining it with your diabetes medication could lower your blood sugar too much. You need to talk with your doctor or pharmacist before adding this powder — they may need to adjust your medication or monitor your blood sugar more closely.
Is this safe if I have liver disease?
Rare but serious liver injury has been reported after taking Tinospora cordifolia, including autoimmune hepatitis and acute liver failure in some cases. If you have liver disease or any history of liver problems, discuss this product with your doctor or pharmacist before use — it should be used only under medical guidance.
What are the most common side effects?
When taken by mouth, the most common side effects reported are headache and nasal pain. The powder seems to be well tolerated overall, but liver injury is a rare serious concern.
Can I take this while pregnant or breastfeeding?
The safety data advises against use in pregnancy. During breastfeeding, there isn't enough reliable information, so it's best avoided. Talk with your doctor or pharmacist about whether this is right for you if you're pregnant, nursing, or planning to become pregnant.
Does this actually work for diabetes?
Clinical research in adults with type 2 diabetes shows Tinospora cordifolia can reduce fasting blood glucose and glycated hemoglobin, so it's rated possibly effective for diabetes. For other conditions on the label, the evidence isn't established yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Guduchi Powder label
Go deeper

The Full Monographs Behind Guduchi Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tinospora Cordifolia

Interacts with 612 drugs

Tinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat fevers. Early laboratory and small human studies s...

Read the full Tinospora Cordifolia monograph →
Sources

Sources & How We Checked

Guduchi Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tinospora Cordifolia 16 references
  1. Stanely Mainzen Prince P, Menon VP. Hypoglycaemic and hypolipidaemic action of alcohol extract of Tinospora cordifolia roots in chemical induced diabetes in rats. Phytother Res 2003;17:410-3.
  2. Grover JK, Vats V, Rathi SS. Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J Ethnopharmacol 2000;73:461-70. PubMed
  3. Manjrekar PN, Jolly CI, Narayanan S. Comparative studies of the immunomodulatory activity of Tinospora cordifolia and Tinospora sinensis. Fitoterapia 2000;71:254-7. PubMed
  4. Prince PS, Menon VP. Antioxidant activity of Tinospora cordifolia roots in experimental diabetes. J Ethnopharmacol 1999;65:277-81. PubMed
  5. Stanely Mainzen Prince P, Menon VP, Gunasekaran G. Hypolipidaemic action of Tinospora cordifolia roots in alloxan diabetic rats. J Ethnopharmacol 1999;64:53-7. PubMed
  6. Badar VA, Thawani VR, Wakode PT, et al. Efficacy of Tinospora cordifolia in allergic rhinitis. J Ethnopharmacol 2005;96:445-9. PubMed
  7. Kapil A, Sharma S. Immunopotentiating compounds from Tinospora cordifolia. J Ethnopharmacol 1997;58:89-95. PubMed
  8. Nair PK, Rodriguez S, Ramachandran R, et al. Immune stimulating properties of a novel polysaccharide from the medicinal plant Tinospora cordifolia. Int Immunopharmacol 2004;4:1645-59. PubMed
  9. Castillo AL, Osi MO, Ramos JD, De Francia JL, Dujunco MU, Quilala PF. Efficacy and safety of Tinospora cordifolia lotion in Sarcoptes scabiei var hominis-infected pediatric patients: A single blind, randomized controlled trial. J Pharmacol Pharmacother. 2 PubMed
  10. Sahu R, Ahmed T, Sangana R, Punde R, Subudhi BB. Effect of Tinospora cordifolia aqua-alcoholic extract on pharmacokinetic of glibenclamide in rat: an herb-drug interaction study. J Pharm Biomed Anal. 2018;151:310-6. doi: 10.1016/j.jpba.2018.01.010. PubMed
  11. Patial V, Katoch S, Chhimwal J, Singh PP, Suresh PS, Padwad Y. Tinospora cordifolia activates PPAR? pathway and mitigates glomerular and tubular cell injury in diabetic kidney disease. Phytomedicine 2021;91:153663. PubMed
  12. Kulkarni AV, Hanchanale P, Prakash V, et al. Tinospora Cordifolia (Giloy)-Induced Liver Injury During the COVID-19 Pandemic-Multicenter Nationwide Study From India. Hepatol Commun 2022;6(6):1289-1300. PubMed
  13. Nagral A, Adhyaru K, Rudra OS, Gharat A, Bhandare S. Herbal Immune Booster-Induced Liver Injury in the COVID-19 Pandemic - A Case Series. J Clin Exp Hepatol. 2021;11(6):732-738. PubMed
  14. Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. PubMed
  15. Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed
  16. May K, Jeitler M, Murthy V, Stapelfeldt E, Kessler CS. A Case Report of Acute Hepatitis Involving the Medicinal Herb Tinospora cordifolia Along with Other Variables. J Integr Complement Med 2023;29(5):327-333.

See these in context on the Tinospora Cordifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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