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Dietary supplement

Gurmar Ingredients & Drug Interactions

by Herbal Hills

Gurmar label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Gurmar against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Gurmar is a dietary supplement by Herbal Hills with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, type 2 diabetes, sugar cravings.Based on those ingredients, 851 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gurmar extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Gurmar by Herbal Hills

Ask about any prescription or over-the-counter medication and we check it for interactions with Gurmar by Herbal Hills — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Gurmar by Herbal Hills

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: gurmar extract, derived from gymnema, a plant used in traditional medicine. Gymnema's role in herbal practice is tied to its effects on blood sugar metabolism and glucose handling, though the evidence for specific health outcomes remains limited in the data we hold.

The capsules also contain inactive ingredients—silicon dioxide, maize starch, and the HPMC capsule material itself—which serve as fillers and the capsule shell.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gymnema's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: blood sugar and glucose support.
  • We looked for evidence on: Diabetes, Impaired glucose tolerance (prediabetes), Metabolic syndrome, Obesity, glycemic control, insulin sensitivity.
  • The closest evidence on file: Gymnema is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Gymnema is rated "Insufficient Reliable Evidence To Rate" for Obesity, Impaired glucose tolerance (prediabetes), Metabolic syndrome.

The evidence we have on gurmar extract is insufficient to make a reliable claim about its use for diabetes, obesity, prediabetes (impaired glucose tolerance), or metabolic syndrome. While animal and some human studies hint that gymnema may affect blood sugar, the current data doesn't establish that it works well enough or consistently enough to recommend it for any of these conditions.

If you're considering it for one of these purposes, that's a conversation to have with your doctor.

The evidence, ingredient by ingredient Gymnema

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gurmar extract is generally well tolerated over short periods, but quality varies between products, and the main safety concern is that it can lower your blood sugar. Over longer use or at higher doses, caution is warranted.

Rare but serious cases of liver inflammation (hepatitis) and liver-related blood disorders have been reported in people taking gymnema—including one case tied to heavy daily use as tea. The safety data is too limited to recommend this product during pregnancy or while breastfeeding; those are reasons to avoid it unless your own doctor advises otherwise.

Side effects, ingredient by ingredient Gymnema

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gymnema.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 852 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist about any antidiabetes or blood sugar medications you take—gymnema can lower blood sugar further and raise the risk of hypoglycemia. Also double-check any drugs metabolized by CYP1A2, CYP2C9, or CYP3A4 enzymes, as gymnema may alter how your body clears them.

Phenacetin and tolbutamide (Orinase) are older medications with documented interaction data; if you take either, flagging this product beforehand is important.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Gurmar extract is best suited for people curious about traditional herbal approaches and willing to monitor their blood sugar closely—especially if they take diabetes medications or liver-metabolized drugs. Anyone on blood sugar medications, or taking drugs broken down by CYP1A2, CYP2C9, or CYP3A4 enzymes, should confirm it's safe for them before starting.

Pregnant or breastfeeding people should not use it without explicit guidance from their own doctor. Run your complete medication list through the checker on this page and discuss the result with your pharmacist or physician.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Gurmar, straight from the product label.

Brand Herbal Hills
Barcode (UPC) 8906068413597
Net contents 120 Vegi Capsule(s)
Market status On market
Date entered into DSLD Jun 23, 2017
DSLD ID 75077
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Gurmar by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
8906068413597
IngredientAmount% DV
Gurmar extract250 mg--

Other ingredients: Silicon Dioxide, Maize Starch, HPMC Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

General Statements

Mfg. Lic. No. : PD/AYU/002/10

Product name: Gurmarhills

(An ISO 22000:2005 Certified Company)

Back to nature

Healthy blood sugar

~ Pure ~ Natural ~ Effective

Gurmar is also known as Meshashringi or Gymnema. It is a popular choice of herbs for effective sugar management. It also helps to maintain healthy lipid levels.

Contents based on standard raw material as per ayurvedic text

Seals/Symbols

JAS-ANZ ICS ISO 22000:2005 Reg. No.: RH91/7301

GMP Good Manufacturing Practice

Halal India www.halalindia.com

Storage

Store in a cool dry place away from sunlight.

Precautions

Keep out of reach of children.

Do not use if inner seal is broken or missing.

Caution: Pregnant or lactating women are advised to consume herbal products under the advice of the healthcare practitioner.

Formula

Standardized extract / 25% Gymnemic acid

Suggested/Recommended/Usage/Directions

Directions For Use: As a dietary supplement take 1 capsule twice daily, preferably before meals. It should ideally be taken on empty stomach. For better results it should be taken with warm water

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Gurmar by Herbal Hills label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Gurmar label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Gurmar by Herbal Hills

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Gurmar extract

Interacts with
851 drugs
250 mg per serving Form: Gymnemic Acid

Gymnema is an Ayurvedic herb best known for possibly helping lower blood sugar and reducing the taste of sweetness on the tongue. Some early human stu...

Gurmar extract monograph & interactions

Other (inactive) ingredients: Silicon Dioxide, Maize Starch, HPMC Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Gurmar by Herbal Hills Drug Interactions

Want to check YOUR meds against Gurmar?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
851Drugs
347 Moderate 504 Minor

Ingredients driving the most interactions

Gurmar extract 851

Individual Drug Interactions

The ingredients in Gurmar interact with 851 drugs. Click any drug to see the details.

1 of the 1 ingredient in Gurmar interact with drugs. Each result below shows which ingredient is responsible. Gurmar extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Gurmar with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Gurmar extract6 drug types · 851 drugs

Antidiabetes Drugs

Theoretically, taking gymnema with antidiabetes drugs might increase the risk of hypoglycemia.
Gymnema reduces blood glucose levels in some human and animal research. In human studies, it has been shown to enhance the blood glucose lowering effects of hypoglycemic drugs. However, other research in adults with prediabetes or metabolic syndrome suggests that gymnema does not reduce fasting levels of blood glucose. Until more is known, monitor blood glucose levels closely.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Animal and in vitro research shows that gymnema can inhibit the CYP1A2 enzyme. In one animal study, oral administration of gymnema for 7 days increased the plasma concentrations of phenacetin, a CYP1A2 substrate, by about 1.4-fold and reduced the clearance of phenacetin by about 29%.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, gymnema might increase or decrease levels of drugs metabolized by CYP2C9.
Animal research shows that gymnema can induce the CYP2C9 enzyme. In one animal study, gymnema caused a 2.4-fold increase in the clearance of tolbutamide, a CYP2C9 substrate, in rats. In vitro research also shows that gymnema can inhibit CYP2C9.

Likelihood Possible Evidence D
Phenacetin

Theoretically, taking gymnema with phenacetin might increase the levels of phenacetin.
Animal research shows that gymnema, administered orally for 7 days, decreases the clearance of phenacetin in a dose-dependent manner by about 21% to 29% and increases plasma levels about 1.3- to 1.4-fold when compared to control.

Likelihood Possible Evidence D
Tolbutamide (Orinase)

Theoretically, taking gymnema with tolbutamide might the decrease levels of tolbutamide.
Animal research shows that gymnema, administered orally for 7 days, increases the clearance of tolbutamide by 2.4-fold when compared to control.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
One in vitro study using rat liver microsomes shows that gymnema can modestly inhibit the CYP3A4 enzyme. However, other in vitro research using human liver microsomes shows that gymnema does not affect CYP3A4 activity. Animal research also shows that gymnema does not alter the function of CYP3A4. In one study in rats, oral administration of gymnema for 7 days did not alter the clearance of amlodipine, a CYP3A4 substrate.

Likelihood Unlikely Evidence D
Gurmar extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Gurmar, from the product label.

Herbal Hills

See all Herbal Hills products
Name
Isha Agro Developers Pvt. Ltd.
Street Address
55-A/B, Lonavala Co-op. Indl. Est. Ltd.
City
Nangargaon, Lonavala, Taluka-Maval, Dist. Pune,
State
Maharashtra
ZipCode
410401
Web Address
0091 22 2868 6868
Pharmacist Counseling Corner

Gurmar by Herbal Hills: Common Questions

Does Gurmar by Herbal Hills interact with any medications?
Yes. Based on its ingredients, Gurmar has a known interaction with 851 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Gurmar contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does gurmar actually help with blood sugar or diabetes?
The evidence in our data is insufficient to say it works reliably for diabetes, prediabetes, obesity, or metabolic syndrome. Animal studies and some human research suggest gymnema may affect glucose, but we don't have strong enough proof for a clear recommendation. Talk to your doctor about whether it makes sense for you.
Can I take this if I'm on insulin or other diabetes medications?
Not without checking first. Gymnema lowers blood sugar on its own and can enhance the effect of diabetes drugs, which raises the risk of low blood sugar (hypoglycemia). Check with your doctor or pharmacist before combining them.
What are the side effects?
Short-term use is generally well tolerated. Rare but serious cases of liver inflammation have been reported, especially with heavy daily use. The main risk is low blood sugar if you take it alongside diabetes medications. Quality varies between products, so sourcing matters too.
Is it safe during pregnancy or breastfeeding?
No. The safety data is too limited, so it's best avoided during pregnancy and while breastfeeding. Talk with your doctor if you're pregnant, planning to become pregnant, or nursing.
Will this interact with my other medications?
Possibly. Gymnema affects how your liver breaks down certain drugs and can lower blood sugar, so it may interact with medications processed by specific liver enzymes (CYP1A2, CYP2C9, CYP3A4) or with any blood sugar drugs. Use the checker below with your exact medications to find out.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Gurmar label
Go deeper

The Full Monographs Behind Gurmar’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gymnema

Interacts with 851 drugs

Gymnema is an Ayurvedic herb best known for possibly helping lower blood sugar and reducing the taste of sweetness on the tongue. Some early human studies are encouraging for blood sugar sup...

Read the full Gymnema monograph →
Sources

Sources & How We Checked

Gurmar's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gymnema 12 references
  1. Shanmugasundaram ER, Rajeswari G, Baskaran K, et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharmacol 1990;30:281-94. PubMed
  2. Baskaran K, Kizar Ahamath B, Radha Shanmugasundaram K, Shanmugasundaram ER. Antidiabetic effect of leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharmacol 1990;30:295-300.
  3. Kamble B, Gupta A, Moothedath I, Khatal L, Janrao S, Jadhav A, et al. Effects of Gymnema sylvestre extract on the pharmacokinetics and pharmacodynamics of glimepiride in streptozotocin induced diabetic rats. Chem Biol Interact. 2016;245:30-8. PubMed
  4. Tiwari P, Mishra BN, Sangwan NS. Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant. Biomed Res Int. 2014; 2014:830285.
  5. Fabio GD, Romanucci V, De Marco A, Zarrelli A. Triterpenoids from Gymnema sylvestre and their pharmacological activities. Molecules. 2014;19(8):10956-81. PubMed
  6. Shiyovich A, Sztarkier I, Nesher L. Toxic hepatitis induced by Gymnema sylvestre, a natural remedy for type 2 diabetes mellitus. Am J Med Sci. 2010;340(6):514-7. PubMed
  7. Zuniga LY, Gonzalez-Ortiz M, Martinez-Abundis E. Effect of gymnema sylvestre administration on metabolic syndrome, insulin sensitivity, and insulin secretion. J Med Food. 2017 Aug;20(8):750-54.
  8. Rammohan B, Samit K, Chinmoy D, et al. Human cytochrome P450 enzyme modulation by gymnema sylvestre: a predictive safety evaluation by LC-MS/MS. Pharmacogn Mag. 2016 Jul;12(Suppl 4):S389-S394.
  9. Vaghela M, Sahu N, Kharkar P, Pandita N. In vivo pharmacokinetic interaction by ethanolic extract of gymnema sylvestre with CYP2C9 (tolbutamide), CYP3A4 (amlodipine) and CYP1A2 (phenacetin) in rats. Chem Biol Interact. 2017 Dec 25;278:141-151. PubMed
  10. Vaghela M, Iyer K, Pandita N. In vitro inhibitory effect of gymnema sylvestre extracts and total gymnemic acids fraction on select cytochrome P450 activities in rat liver microsomes. Eur J Drug Metab Pharmacokinet. 2017 Oct 10. PubMed
  11. Gaytán Martínez LA, Sánchez-Ruiz LA, Zuñiga LY, González-Ortiz M, Martínez-Abundis E. Effect of Gymnema sylvestre administration on glycemic control, insulin secretion, and insulin sensitivity in patients with impaired glucose tolerance. J Med Food. 2021;
  12. Philips CA, Theruvath AH, Ravindran R. Toxic hepatitis-associated aplastic anaemia after dual homeopathic remedies and Gymnema sylvestre use. BMJ Case Rep 2022;15(3):e247867. PubMed

See these in context on the Gymnema monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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