Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Hairfluence Watermelon Ingredients & Drug Interactions

by ZHOU

Liquid Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Hairfluence Watermelon is a dietary supplement by ZHOU with 3 active ingredients. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.Based on those ingredients, 5 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bamboo stem extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Hairfluence Watermelon by ZHOU

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 3 active ingredients.
  • “Hairfluence Blend” is a proprietary blend — the label gives one combined amount (23 mg) without saying how much of each component you get.
  • “Bamboo stem extract” is listed as a grouped ingredient — the label gives one combined amount (23 mg) without saying how much of each component you get.

Hairfluence Watermelon is a liquid supplement with 3 active ingredients. Silica (a form of silicon) is included for bone and connective tissue support.

Biotin is a B vitamin that helps cells convert food into energy and plays a role in hair, skin, and nail health. Keratin is a structural protein that forms the core of hair strands.

The product also contains inactive ingredients — purified water, natural watermelon flavor, citric acid, stevia leaf extract, vegetable juice concentrate, potassium sorbate, and acacia gum — which serve as the liquid base, flavor, sweetener, and preservatives.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: longer, stronger, healthier hair growth.
  • We looked for evidence on: Androgenic alopecia, Alopecia areata, Brittle nails, Biotin deficiency, hair thinning, hair loss — and 1 related terms.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Alopecia areata, Brittle nails.
  • Also on file: Silicon is rated "Insufficient Reliable Evidence To Rate" for Androgenic alopecia.

Silica shows possibly effective evidence for osteoporosis support, though the evidence for hair loss (androgenic alopecia) is insufficient to rate. Biotin is likely effective for true biotin deficiency, but shows possibly ineffective ratings for multiple sclerosis and seborrheic dermatitis; evidence for alopecia areata is insufficient.

We don't have effectiveness data on file for keratin in this product. The evidence for how well this supplement works to promote hair health specifically is not established in the data we hold.

The evidence, ingredient by ingredient Biotin Bamboo

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Silica from food and supplements is generally well tolerated at typical doses, though long-term high-dose safety hasn't been thoroughly studied. The safety data advises against silica during pregnancy and breastfeeding.

Biotin is generally considered safe and well tolerated, even at fairly high doses, since excess amounts are cleared through urine; a small number of people taking high-dose biotin have reported mild diarrhea. Biotin is likely safe in pregnancy and breastfeeding at normal dietary and supplement amounts, though check with your doctor about high-dose products.

Pregnancy and breastfeeding safety data for keratin is not on file.

Side effects, ingredient by ingredient Biotin Bamboo

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients in this product that we could check. If you take any medications at all, confirm with your own doctor or pharmacist before starting — this page gives you the detail they'll want to see.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Hairfluence Watermelon is a liquid hair supplement with silica, biotin, and keratin — three ingredients chosen to support hair structure and health. If you take medications, use the interaction checker on this page for your exact drugs, though no interactions are documented for the ingredients we could verify.

Talk with your doctor or pharmacist before starting, especially if you're pregnant or breastfeeding, or if you take any prescription or over-the-counter drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hairfluence Watermelon, straight from the product label.

Brand ZHOU
Barcode (UPC) 669191383516
Net contents 1.69 Fluid Ounce(s); 50 mL
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 250014
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hairfluence Watermelon by ZHOU, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 mL
Maximum serving Sizes:
5 mL
Servings per container
10
UPC/BARCODE
669191383516
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Silica6 mg--
Biotin5000 mcg1667%
Keratin0 NP--
Hairfluence Blend23 mg--
Bamboo stem extract23 mg--

Other ingredients: purified Water, natural Watermelon flavor, Citric Acid, organic Stevia leaf extract, Vegetable juice concentrate, Potassium Sorbate, Acacia Gum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Premium hair growth formula Nutrient-infused Water enhancer

No added sugar

Formulated for longer, stronger, healthier hair

General Statements

10 Servings

Formula

Watermelon natural flavor

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Add 1 teaspoon (5 mL) or approximately 2 squeezes to 8 oz of water.

Precautions

Caution: Do not use if safety seal is broken or missing.

Keep out of reach of children.

Keep your licensed health care practitioner informed when using this product.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Hairfluence Watermelon by ZHOU label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Hairfluence Watermelon by ZHOU

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 mL Dosage formLiquid Servings per container10 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Biotin

No known
interactions
5000 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Hairfluence Blend

23 mg per serving

Other (inactive) ingredients: Purified Water, Natural Watermelon flavor, Citric Acid, Organic Stevia leaf extract, Vegetable juice concentrate, Potassium Sorbate, Acacia Gum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hairfluence Watermelon by ZHOU Drug Interactions

Want to check YOUR meds against Hairfluence Watermelon?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
5Drugs
5 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Hairfluence Watermelon with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bamboo stem extract1 drug type · 5 drugs

Antithyroid Drugs

Theoretically, long-term bamboo use might increase the effects and adverse effects of antithyroid drugs, possibly leading to hypothyroidism.
Animal research suggests that long-term consumption of bamboo shoot can decrease thyroid peroxidase activity, as well as levels of thyroxine (T4) and triiodothyronine (T3). This effect has not yet been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Hairfluence Watermelon, from the product label.

ZHOU

See all ZHOU products
Name
ZHOU Nutrition Zhou, Inc.
City
Park City
State
UT
ZipCode
84098
Phone Number
1-855-700-9468
Web Address
zhounutrition.com
Pharmacist Counseling Corner

Hairfluence Watermelon by ZHOU: Common Questions

Does Hairfluence Watermelon by ZHOU interact with any medications?
Yes. Based on its ingredients, Hairfluence Watermelon has a known interaction with 5 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hairfluence Watermelon contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy?
Silica safety data advises against it during pregnancy. Biotin is likely safe at normal dietary amounts, but you should talk with your doctor or pharmacist before taking supplements during pregnancy, as safety data for keratin is not on file.
Is this safe while breastfeeding?
Silica safety data advises against it while breastfeeding. Biotin is likely safe at normal amounts, but check with your doctor or pharmacist about this product while nursing, since we don't have breastfeeding safety data for keratin.
Will this help with hair loss?
Biotin has insufficient evidence for alopecia areata, and silica's evidence for androgenic alopecia (male or female pattern hair loss) is also insufficient to rate. The effectiveness of this supplement for hair loss specifically is not well established in the data we hold.
What does biotin do?
Biotin is a B vitamin that helps your cells turn food into energy and plays a role in hair, skin, and nail health. It's likely effective if you have a true biotin deficiency, though that's rare in people eating a typical diet.
Why is silica in this product?
Silica (a form of silicon) is included because it shows possibly effective evidence for osteoporosis support. It's generally well tolerated at typical supplement doses, though long-term safety at high doses hasn't been well studied.
What side effects might I experience?
Both silica and biotin are generally well tolerated. High-dose biotin has rarely caused mild diarrhea in a small number of people. Silica from food and supplements at normal amounts is not associated with adverse effects.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hairfluence Watermelon is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hairfluence Watermelon label
Sources

Sources & How We Checked

Hairfluence Watermelon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Silicon 19 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  2. Jugdaohsingh R, Anderson SH, Tucker KL, et al. Dietary silicon intake and absorption. Am J Clin Nutr 2002;75:887-93. PubMed
  3. Ichiyanagi O, Sasagawa I, Adachi Y, et al. Silica urolithiasis without magnesium trisilicate intake. Urol Int 1998;61:39-42. PubMed
  4. Levison DA, Crocker PR, Banim S, Wallace DM. Silica stones in the urinary bladder. Lancet 1982;1:704-5. PubMed
  5. Lee MH, Lee YH, Hsu TH, et al. Silica stone--development due to long time oral trisilicate intake. Scand J Urol Nephrol 1993;27:267-9. PubMed
  6. Cruz Guerra, N. A., Gomez Garcia, M. A., Lovaco, Castellano F., Saez Garrido, J. C., Garcia, Cuerpo E., and Escudero, Barrilero A. [Silica urolithiasis: report of a new case]. Actas Urol.Esp 2000;24(2):202-204.
  7. Merget, R., Bauer, T., Kupper, H. U., Philippou, S., Bauer, H. D., Breitstadt, R., and Bruening, T. Health hazards due to the inhalation of amorphous silica. Arch Toxicol. 2002;75(11-12):625-634. PubMed
  8. Khuder, S. A., Peshimam, A. Z., and Agraharam, S. Environmental risk factors for rheumatoid arthritis. Rev Environ Health 2002;17(4):307-315. PubMed
  9. McLaughlin, J. K., Chow, W. H., and Levy, L. S. Amorphous silica: a review of health effects from inhalation exposure with particular reference to cancer. J Toxicol.Environ Health 4-25-1997;50(6):553-566. DOI
  10. Pelucchi, C., Pira, E., Piolatto, G., Coggiola, M., Carta, P., and La, Vecchia C. Occupational silica exposure and lung cancer risk: a review of epidemiological studies 1996-2005. Ann.Oncol. 2006;17(7):1039-1050. PubMed
  11. Gillissen, A., Gessner, C., Hammerschmidt, S., Hoheisel, G., and Wirtz, H. [Health significance of inhaled particles]. Dtsch.Med Wochenschr. 3-24-2006;131(12):639-644.
  12. Hu, J. F., Qu, H., and Wang, J. Z. [Meta analysis for relationship between exposure of free silicon dioxide and lung tumor]. Zhonghua Lao.Dong.Wei Sheng Zhi.Ye.Bing.Za Zhi. 2006;24(7):415-417.
  13. Jugdaohsingh, R. Silicon and bone health. J Nutr Health Aging 2007;11(2):99-110.
  14. Lacasse, Y., Martin, S., Gagne, D., and Lakhal, L. Dose-response meta-analysis of silica and lung cancer. Cancer Causes Control 2009;20(6):925-933. PubMed
  15. McCormic, Z. D., Khuder, S. S., Aryal, B. K., Ames, A. L., and Khuder, S. A. Occupational silica exposure as a risk factor for scleroderma: a meta-analysis. Int Arch Occup.Environ Health 2010;83(7):763-769. PubMed
  16. Haddad, F. S. and Kouyoumdjian, A. Silica stones in humans. Urol.Int 1986;41(1):70-76. PubMed
  17. Tervaert, J. W., Stegeman, C. A., and Kallenberg, C. G. Silicon exposure and vasculitis. Curr Opin.Rheumatol 1998;10(1):12-17. PubMed
  18. Steenland, K. and Stayner, L. Silica, asbestos, man-made mineral fibers, and cancer. Cancer Causes Control 1997;8(3):491-503. PubMed
  19. Boqué N, Valls RM, Pedret A, Puiggrós F, Arola L, Solà R. Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study. Sci Rep 2021;11(1):16479. PubMed

See these in context on the Silicon monograph →

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Bamboo 4 references
  1. Chandra AK, Ghosh D, Mukhopadhyay S, et al. Effect of bamboo shoot, Bambusa arundinacea (Retz.) Willd. on thyroid status under conditions of varying iodine intake in rats. Indian J Exp Biol 2004;42(8):781-786.
  2. Kitajima T. Contact allergy caused by bamboo shoots. Contact Dermatitis 1986;15(2):100-102. PubMed
  3. Sang-A-Gad P, Guharat S, Wananukul W. A mass cyanide poisoning from pickling bamboo shoots. Clin Toxicol (Phila). 2011 Nov;49(9):834-9. PubMed
  4. Satya S, Bal LM, Singhal P, Naik SN. Bamboo shoot processing: food quality and safety aspect (a review). Trends in Food Sci. Technol. 2010;21(4):181-9. DOI

See these in context on the Bamboo monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring