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Dietary supplement

Hawaiian Astaxanthin 4 mg Ingredients & Drug Interactions

by BioAstin

Hawaiian Astaxanthin 4 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hawaiian Astaxanthin 4 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hawaiian Astaxanthin 4 mg is a dietary supplement by BioAstin with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin, Natural. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Hawaiian Astaxanthin 4 mg by BioAstin

Ask about any prescription or over-the-counter medication and we check it for interactions with Hawaiian Astaxanthin 4 mg by BioAstin — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Hawaiian Astaxanthin 4 mg by BioAstin

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: natural astaxanthin at 4 mg per softgel capsule. Astaxanthin is a carotenoid — a naturally occurring pigment — extracted from microalgae.

The capsule also holds several inactive ingredients: safflower oil (high oleic), bovine gelatin, glycerin, purified water, and vitamin E. These serve as the carrier and capsule material.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Immune, eye, skin, joint, cardiovascular health and exercise recovery.
  • We looked for evidence on: Age-related macular degeneration (AMD), Aging skin, Athletic performance, Dry eye, Exercise-induced muscle damage, Exercise-induced muscle soreness — and 4 related terms.
  • The closest evidence on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Athletic performance, Heart failure, Dry eye, and more.

The evidence we hold doesn't establish whether astaxanthin works for any of its common uses. Our data rates its effectiveness as insufficient for age-related cognitive decline, age-related macular degeneration (AMD), aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome.

That doesn't mean it doesn't work — just that the reliable evidence isn't there yet in our records.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects reported orally are abdominal pain, diarrhea, and red-colored stools.

A small number of people taking higher doses (40 mg daily) experienced severe stomach or abdominal pain. The safety data advises against use during pregnancy and while breastfeeding due to insufficient information.

If you're pregnant, planning to become pregnant, or breastfeeding, talk with your pharmacist or doctor before taking this supplement.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking BioAstin, check any medications you're on that are metabolized by the liver enzyme CYP3A4 (Moderate severity) — astaxanthin may lower their levels and reduce effectiveness. Also check drugs metabolized by CYP2B6 (Moderate severity), which face the same concern.

Use the search tool on this page with your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

BioAstin astaxanthin is generally well tolerated, but it may interact with medications your liver processes. If you take any prescription drugs — especially ones broken down by CYP3A4 or CYP2B6 enzymes — check them against the interaction tool on this page first.

Long-term safety data are limited, and it's not recommended during pregnancy or breastfeeding. Ask your pharmacist if you're unsure whether this is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hawaiian Astaxanthin 4 mg, straight from the product label.

Brand BioAstin
Barcode (UPC) 732894400337
Net contents 270 Softgel(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 320598
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hawaiian Astaxanthin 4 mg by BioAstin, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
3 Softgel(s)
Servings per container
90
UPC/BARCODE
732894400337
IngredientAmount% DV
Calories15 Calorie(s)--
Calories from Fat10 Calorie(s)--
Total Fat1.5 Gram(s)2%
Astaxanthin, Natural12 mg--

Other ingredients: Safflower Oil, High Oleic, Bovine Gelatin, Glycerin, Water, Purified, Vitamin E

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Human clinical studies have demonstrated Astaxanthin's support for: Immune health Eye health Skin health during UV/Sun exposure Joint health Cardiovascular health Recovery from exercise

Free of soy, gluten, lactose, yeast, corn & wheat. Pesticide, herbicide, & BSE free. No artificial colors. Made with non-GMO project verified BioAstin Natural Astaxanthin.

IGEN Non-GMO Tested Glyphosate Residue Free detoxfreeproject.org Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

For immune, eye, skin & joint health

Naturally grown on our farm at Keahole Point in Hawaii Since 1990.

Nature's powerful antioxidant

General Statements

Setting the standard for microalgae since 1984

Farm Grown For your wellbeing Since 1984

Value size

Results are usually seen within 2 to 6 weeks of daily use.

Made with Aloha.

Precautions

Consult your healthcare practitioner before use if you are pregnant or nursing.

Do not use if outer seal is broken.

Formula

Made with non-GMO project verified BioAstin Natural Astaxanthin.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Copyright 2020 Nutrex Hawaii

Seals/Symbols

IGEN Non-GMO Tested Glyphosate Residue Free detoxfreeproject.org Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

3 Per Day

Suggested Use: One to three soft gels daily with food, BioAstin is best absorbed when taken with food or meal that contains fat.

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hawaiian Astaxanthin 4 mg by BioAstin label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hawaiian Astaxanthin 4 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hawaiian Astaxanthin 4 mg by BioAstin

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container90 Amounts shown are per serving.

Astaxanthin, Natural

Interacts with
671 drugs
12 mg per serving Form: Haematococcus pluvialis

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin, Natural monograph & interactions

Other (inactive) ingredients: Safflower Oil, High Oleic, Bovine Gelatin, Glycerin, Water, Purified, Vitamin E. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hawaiian Astaxanthin 4 mg by BioAstin Drug Interactions

Want to check YOUR meds against Hawaiian Astaxanthin 4 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

Astaxanthin, Natural 671

Individual Drug Interactions

The ingredients in Hawaiian Astaxanthin 4 mg interact with 671 drugs. Click any drug to see the details.

1 of the 1 ingredient in Hawaiian Astaxanthin 4 mg interact with drugs. Each result below shows which ingredient is responsible. Astaxanthin, Natural

Each ingredient & the kinds of drugs it affects

For each ingredient in Hawaiian Astaxanthin 4 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin, Natural2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Astaxanthin, Natural full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hawaiian Astaxanthin 4 mg, from the product label.

BioAstin

See all BioAstin products
Name
Nutrex Hawaii Inc.
City
Kailua-Kona
State
HI
ZipCode
96740
Phone Number
800-453-1187
Web Address
nutrex-hawaii.com
Pharmacist Counseling Corner

Hawaiian Astaxanthin 4 mg by BioAstin: Common Questions

Does Hawaiian Astaxanthin 4 mg by BioAstin interact with any medications?
Yes. Based on its ingredients, Hawaiian Astaxanthin 4 mg has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hawaiian Astaxanthin 4 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against it — there isn't enough information to know either way. Talk with your pharmacist or doctor before using astaxanthin during pregnancy or while breastfeeding.
What are the side effects?
Most common are abdominal pain, diarrhea, and red-colored stools. A small number of people on higher doses reported severe stomach pain. Astaxanthin is generally well tolerated, but long-term safety data are limited.
Does this actually work for anti-aging or brain health?
We don't have reliable evidence in our data to say whether it works for those uses. The evidence is rated insufficient for aging skin, age-related cognitive decline, AMD, Alzheimer disease, and other common claims.
Is this a carotenoid like beta-carotene?
Yes — astaxanthin is a carotenoid, which is a naturally occurring pigment. This product uses natural astaxanthin extracted from microalgae.
What's in the capsule besides the active ingredient?
The capsule contains safflower oil, bovine gelatin, glycerin, purified water, and vitamin E. These are inactive ingredients that serve as the carrier and capsule material.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hawaiian Astaxanthin 4 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hawaiian Astaxanthin 4 mg label
Go deeper

The Full Monographs Behind Hawaiian Astaxanthin 4 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Hawaiian Astaxanthin 4 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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