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Dietary supplement

Hawaiian Astaxanthin 12 mg Ingredients & Drug Interactions

by BioAstin

Hawaiian Astaxanthin 12 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hawaiian Astaxanthin 12 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hawaiian Astaxanthin 12 mg is a dietary supplement by BioAstin with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin, Natural. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Hawaiian Astaxanthin 12 mg by BioAstin

Ask about any prescription or over-the-counter medication and we check it for interactions with Hawaiian Astaxanthin 12 mg by BioAstin — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Hawaiian Astaxanthin 12 mg by BioAstin

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

BioAstin contains one active ingredient: 12 mg of natural astaxanthin per softgel, a carotenoid (a plant pigment) from microalgae. The capsule also holds inactive ingredients — high oleic safflower oil, gelatin, glycerine, purified water, and vitamin E — which help deliver and preserve the astaxanthin.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune eye skin joint cardiovascular health.
  • We looked for evidence on: Age-related macular degeneration (AMD), Aging skin, Sunburn, Dry eye, Heart failure, Hyperlipidemia — and 4 related terms.
  • The closest evidence on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Heart failure, Dry eye, Hyperlipidemia, and more.

The evidence for astaxanthin isn't established yet in the data we hold. We rate it insufficient reliable evidence to determine whether it works for age-related cognitive decline, age-related macular degeneration, aging skin, Alzheimer disease, athletic performance, or carpal tunnel syndrome.

If you're considering it for any of these reasons, talk with your doctor about what the current research actually supports.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated, though long-term safety data are limited. The most common side effects reported are abdominal pain, diarrhea, and red-colored stools — the color change is harmless and comes from the pigment itself.

At the 12 mg dose in this product, these effects appear uncommon; they've been noted more often at higher doses. During pregnancy, there isn't enough safety data, so it's best to avoid it.

The same goes for breastfeeding. If you're pregnant, planning pregnancy, or nursing, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check whether you take any drugs metabolized by the liver enzyme CYP3A4 — the biggest category of concern at moderate severity. Also check for CYP2B6 substrates, another moderate-severity group.

Your pharmacist can tell you right away if any of your medications fall into either category.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

BioAstin may be worth considering if you're interested in astaxanthin and have no medications affected by CYP3A4 or CYP2B6. Because the evidence for its effectiveness isn't solid yet, know that you're taking it on the basis of early research, not proven benefit.

Before you start, check your medications with your doctor or pharmacist — the interaction potential is real, even if it hasn't been confirmed in patients.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hawaiian Astaxanthin 12 mg, straight from the product label.

Brand BioAstin
Barcode (UPC) 732894035188
Net contents 50 Softgel(s)
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 259687
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hawaiian Astaxanthin 12 mg by BioAstin, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
50
UPC/BARCODE
732894035188
IngredientAmount% DV
Calories5 Calorie(s)--
Calories from Fat5 Calorie(s)--
Total Fat0.5 Gram(s)1%
Astaxanthin, Natural12 mg--

Other ingredients: High Oleic Safflower Oil, Gelatin, Glycerine, Water, Purified, Vitamin E

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Human clinical studies have demonstrated Astaxanthin's support for: Immune health Eye health Skin health during UV/sun exposure Joint health Cardiovascular health Recovery from exercise

Free of soy, gluten, lactose, yeast, corn & wheat. Pesticide, herbicide, & BSE free. No artificial colors. Made with Non-GMO Project Verified BioAstin Natural Astaxanthin.

Igen NON-GMO Tested Glyphosate Residue Free Detoxproject.org Certified Gluten Free

Nature's powerful antioxidant for immune, eye, skin & joint health

General Statements

Setting the standard for microalgae since 1984

Made with Aloha.

Farm grown for your well being since 1984

Naturally grown on our farm at Keahole Point in Hawaii since 1990.

Precautions

Consult your healthcare practitioner before use if you are pregnant or nursing.

Do not use if outer seal is broken.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Nutrex Hawaii

Copyright 2020 Nutrex Hawaii

Seals/Symbols

Igen NON-GMO Tested Glyphosate Residue Free Detoxproject.org Certified Gluten Free

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

1 per day

Suggested use: One soft gel with food, BioAstin is best absorbed when taken with food or meal that contains fat. Results are usually seen within 2 to 6 weeks of daily use.

1 per day

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hawaiian Astaxanthin 12 mg by BioAstin label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hawaiian Astaxanthin 12 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hawaiian Astaxanthin 12 mg by BioAstin

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container50 Amounts shown are per serving.

Astaxanthin, Natural

Interacts with
671 drugs
12 mg per serving Form: Haematococcus pluvialis

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin, Natural monograph & interactions

Other (inactive) ingredients: High Oleic Safflower Oil, Gelatin, Glycerine, Water, Purified, Vitamin E. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hawaiian Astaxanthin 12 mg by BioAstin Drug Interactions

Want to check YOUR meds against Hawaiian Astaxanthin 12 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

Astaxanthin, Natural 671

Individual Drug Interactions

The ingredients in Hawaiian Astaxanthin 12 mg interact with 671 drugs. Click any drug to see the details.

1 of the 1 ingredient in Hawaiian Astaxanthin 12 mg interact with drugs. Each result below shows which ingredient is responsible. Astaxanthin, Natural

Each ingredient & the kinds of drugs it affects

For each ingredient in Hawaiian Astaxanthin 12 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin, Natural2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Astaxanthin, Natural full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hawaiian Astaxanthin 12 mg, from the product label.

BioAstin

See all BioAstin products
Name
Nutrex Hawaii Inc.
City
Kailua-Kona
State
HI
ZipCode
96740
Phone Number
800-453-1187
Web Address
nutrex-hawaii.com
Pharmacist Counseling Corner

Hawaiian Astaxanthin 12 mg by BioAstin: Common Questions

Does Hawaiian Astaxanthin 12 mg by BioAstin interact with any medications?
Yes. Based on its ingredients, Hawaiian Astaxanthin 12 mg has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hawaiian Astaxanthin 12 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is astaxanthin, and why is it in this product?
Astaxanthin is a red pigment from microalgae. The product includes it because early research suggests it may support eye, skin, and cognitive health, though the evidence isn't solid enough yet to confirm it actually works for these uses.
Will this turn my stool red?
It might — that's the astaxanthin pigment passing through, and it's harmless. It's more common at higher doses; at 12 mg, it's less likely but still possible.
Can I take this while pregnant or breastfeeding?
No — there isn't enough safety data. If you're pregnant, planning to become pregnant, or nursing, avoid this product and talk with your doctor or pharmacist about whether it's appropriate for your situation.
Are there any fillers or additives I should know about?
The capsule contains safflower oil, gelatin, glycerine, purified water, and vitamin E as inactive ingredients. These help deliver and preserve the astaxanthin but aren't the active part of the supplement.
How long has this supplement been studied for safety?
Astaxanthin is generally well tolerated in the studies we have, but long-term safety data are limited. If you plan to take it long-term, it's worth discussing with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hawaiian Astaxanthin 12 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hawaiian Astaxanthin 12 mg label
Go deeper

The Full Monographs Behind Hawaiian Astaxanthin 12 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Hawaiian Astaxanthin 12 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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