Hops 200 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Hops 200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hops 200 mg is a dietary supplement by Eclectic Herb with 1 active ingredient. Its ingredients are commonly taken for sleep problems and insomnia, anxiety and restlessness, menopausal symptoms.Based on those ingredients, 863 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hops, Freeze-Dried. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Hops 200 mg by Eclectic Herb
Ask about any prescription or over-the-counter medication and we check it for interactions with Hops 200 mg by Eclectic Herb — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Hops 200 mg by Eclectic Herb
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Hops 200 mg contains one active ingredient: freeze-dried hops — a botanical with a long history in herbal medicine. The capsule also contains hypromellose, a common inactive ingredient that forms the capsule wall.
Does it work?
Not established
The evidence we have for hops doesn't yet support its use for any specific condition. Our data rates hops as having insufficient evidence for age-related cognitive decline, sexual dysfunction, anxiety, ADHD, upset stomach (dyspepsia), and insomnia.
That doesn't mean it doesn't work — it means the research we hold isn't conclusive enough to say either way.
How safe is it?
Well-documented data
Hops is generally well tolerated in the short term but commonly causes drowsiness, so avoid driving or operating machinery until you know how it affects you. Long-term safety hasn't been well studied.
During pregnancy, there isn't enough safety information, so it's best to avoid it. The same goes for breastfeeding — safety is unknown, so skip it while nursing.
People exposed to hops dust occupationally have reported chronic respiratory symptoms, and a few cases of postmenopausal bleeding have been linked to supplements containing both hops and soy (though it's unclear which ingredient, if either alone, caused it).
Meds to double-check
Moderate interaction found
Check with your pharmacist if you take sedative medications or anti-anxiety drugs, or if you're on hormone replacement therapy. Also flag any medications your liver metabolizes, especially those processed by the CYP1A2 or CYP3A4 enzymes — your pharmacist can tell you if yours fall into those categories.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Hops might appeal to you if you're exploring herbal options for sleep or anxiety, but the evidence isn't there yet. If you take sedative medications or hormone replacement therapy, talk to your pharmacist before adding hops — the interactions are real.
Pregnancy and breastfeeding are reasons to skip it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hops 200 mg, straight from the product label.
| Brand | Eclectic Herb |
|---|---|
| Barcode (UPC) | 023363309177 |
| Net contents | 90 Veg Cap(s) |
| Market status | On market |
| Date entered into DSLD | Dec 21, 2024 |
| DSLD ID | 316804 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hops 200 mg by Eclectic Herb, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Concentrated 4 1/2 X through freeze-drying Freeze dried fresh for peak plant power Grown in the United States Naturally concentrated
No fillers Non GMO Gluten free
Vegan
Nothing artificial - no fillers or additives.
Freeze-drying is the best method of preservation as it naturally concentrates the nutrients in the plant by removing only the water. Supports relaxation Small batch freeze dried
Formula
100% Kosher
Our hops are locally grown and fresh freeze-dried in-house in small batches.
Whole herb Raw food
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent disease.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: Take 1-3 capsules per day.
Precautions
Keep away from children. Consult your doctor about herbs with pregnancy, infants or prescription drugs.
Consult your doctor about herbs with pregnancy, infants or prescription drugs.
General Statements
@eclecticherb
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hops 200 mg by Eclectic Herb label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hops 200 mg by Eclectic Herb
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Veg Cap(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Hops, Freeze-Dried
Interacts with863 drugs
Hops are most often used for sleep and mild anxiety, frequently combined with valerian, but the human evidence is limited and not very strong. They ar...
Hops, Freeze-Dried monograph & interactionsOther (inactive) ingredients: Hypromellose. These complete the product’s ingredient list but are not active constituents.
Hops 200 mg by Eclectic Herb Drug Interactions
HelloPharmacist Interaction Report
Hops 200 mg by Eclectic Herb does interact with some medication types.
The main concern is with sedative drugs (CNS depressants) — hops has sedative effects of its own, and combining it with prescription sedatives or anti-anxiety medications could add up to too much drowsiness. This is a Moderate-severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Hops may also interfere with hormone replacement therapy (estrogens), though the risk depends on dose; in vitro research shows certain hops constituents can bind to estrogen receptors, but most hops extracts contain very small amounts of these constituents. This is also Moderate severity.
Two other drug types — medications metabolized by the liver enzymes CYP1A2 and CYP3A4 — show Minor-severity interactions. Research suggests hops *might* alter how your body breaks down these drugs, but a human study suggests the effect may not be clinically important in practice.
Altogether, these interactions span 853 individual medications. Use the medication checker on this page to look up your specific prescriptions before starting hops.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Hops 200 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Hops 200 mg interact with 863 drugs. Click any drug to see the details.
1 of the 1 ingredient in Hops 200 mg interact with drugs. Each result below shows which ingredient is responsible. Hops, Freeze-Dried
AcepromazineAtravet
How Acepromazine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Acepromazine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +1 Moderate
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops, Freeze-dried + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +1 Moderate
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops, Freeze-dried + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants +1 Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Acetaminophen, Dichlorophenazone, Isometheptane interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Hydrocodone interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Meperidine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Oxycodone interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Pentazocine interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops, Freeze-dried + Acetaminophen, Propoxyphene interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Acetazolamide interactionAlfentanilAlfenta
How Alfentanil interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops, Freeze-dried + Alfentanil interactionAlprazolamNiravam, Xanax
How Alprazolam interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Alprazolam interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Aminoglutethimide interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with Hops 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Hops, Freeze-driedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops, Freeze-dried + Aminophylline, Amobarbital, Ephedrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Hops 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Hops, Freeze-Dried
Cns Depressants
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Some animal research shows that hops has sedative effects.
Estrogens
Theoretically, concomitant use of large amounts of hops might interfere with hormone replacement therapy due to competition for estrogen receptors.
In vitro research suggests that certain hops constituents can competitively bind to estrogen receptors. However, most hops extracts contain very small amounts of these constituents.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
In vitro research suggests that flavonoid constituents of hops inhibit CYP1A2 enzyme activity. However, a pharmacokinetic study in healthy postmenopausal patients shows that taking a standardized extract of spent hops containing prenylated phenols, as 59.5 mg twice daily for 2 weeks, does not affect levels of caffeine, a CYP1A2 probe substrate.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Animal research suggests that specific constituents of hops, called lupulones, can induce hepatic CYP3A4 enzyme activity. However, a pharmacokinetic study in healthy postmenopausal patients with normal metabolism shows that taking a standardized extract of spent hops containing prenylated phenols, as 59.5 mg twice daily for 2 weeks, decreases the concentration of alprazolam, a CYP3A4 probe substrate, by 7.6%. This reduction is unlikely to be clinically relevant.
Brand information
Manufacturer and brand details for Hops 200 mg, from the product label.
Eclectic Herb
See all Eclectic Herb products- Name
- Eclectic Herb
- Street Address
- 755 NE 6th St.
- City
- Gresham
- State
- Oregon
- ZipCode
- 97030
- Phone Number
- 503.668.4120
- Web Address
- www.eclecticherb.com
Hops 200 mg by Eclectic Herb: Common Questions
Does Hops 200 mg by Eclectic Herb interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will hops make me drowsy?
Is hops safe to take while pregnant?
Can I take hops while breastfeeding?
Does hops actually help with insomnia?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hops 200 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hops 200 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Hops 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 15 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hops 15 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Zava DT, Dollbaum CM, Blen M. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med 1998;217:369-78. PubMed
- Milligan SR, Kalita JC, Heyerick A, et al. Identification of a potent phytoestrogen in hops (Humulus lupulus L.) and beer. J Clin Endocrinol Metab 1999;84:2249-52.. PubMed
- Milligan SR, Kalita JC, Pocock V, et al. The endocrine activities of 8-prenylnaringenin and related hop (Humulus lupulus L.) flavonoids. J Clin Endocrinol Metab 2000;85:4912-5.. DOI
- Henderson MC, Miranda CL, Stevens JF, et al. In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus. Xenobiotica 2000;30:235-51.. PubMed
- Mannering, G. J., Shoeman, J. A., and Deloria, L. B. Identification of the antibiotic hops component, colupulone, as an inducer of hepatic cytochrome P-4503A in the mouse. Drug Metab Dispos 1992;20(2):142-147. DOI
- Skorska, C., Mackiewicz, B., Gora, A., Golec, M., and Dutkiewicz, J. Health effects of inhalation exposure to organic dust in hops farmers. Ann.Univ Mariae.Curie Sklodowska [Med] 2003;58(1):459-465.
- Schiller, H., Forster, A., Vonhoff, C., Hegger, M., Biller, A., and Winterhoff, H. Sedating effects of Humulus lupulus L. extracts. Phytomedicine. 2006;13(8):535-541. PubMed
- van Hunsel, F. P. and Kampschoer, P. [Postmenopausal bleeding and dietary supplements: a possible causal relationship with hop- and soy-containing preparations]. Ned.Tijdschr.Geneeskd. 2012;156(41):A5095.
- Fenselau, C. and Talalay, P. Is oestrogenic activity present in hops? Food Cosmet.Toxicol. 1973;11(4):597-602. PubMed
- Godnic-Cvar, J., Zuskin, E., Mustajbegovic, J., Schachter, E. N., Kanceljak, B., Macan, J., Ilic, Z., and Ebling, Z. Respiratory and immunological findings in brewery workers. Am J Ind Med 1999;35(1):68-75. DOI
- Lee KM, Jung JS, Song DK, and et al. Effects of Humulus lupulus extract on the central nervous system in mice. Planta Med 1993;59(Suppl):A691.
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