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Dietary supplement

Horseradish 450 mg 4:1 Extract Ingredients & Drug Interactions

by TerraVita Premium Collection

Horseradish 450 mg 4:1 Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Horseradish 450 mg 4:1 Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Horseradish 450 mg 4:1 Extract is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for sinus and respiratory congestion, urinary tract infections, digestive support.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horseradish Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Horseradish 450 mg 4:1 Extract by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Horseradish 450 mg 4:1 Extract by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Horseradish 450 mg 4:1 Extract by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: horseradish extract, a 4:1 concentrated form supplying 450 mg per capsule. The capsule itself is made from gelatin and water—the inactive ingredients that hold everything together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Horseradish product and its label doesn't state a use — see Horseradish's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold for horseradish doesn't establish that it works for any of the conditions it's marketed for. We have insufficient reliable evidence to rate its use for respiratory tract infections, intestinal parasite infection, urinary tract infections, or gout.

If you're considering it for one of these reasons, that's worth discussing with your doctor.

The evidence, ingredient by ingredient Horseradish

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Horseradish in food amounts is generally well tolerated. When you consume large amounts—like in concentrated supplements—it can irritate your digestive tract and mucous membranes, and may cause gastrointestinal upset, diarrhea, or bloody vomiting.

In rare cases, consuming large amounts has been linked to vasovagal syncope (a sudden drop in heart rate and blood pressure causing fainting). During pregnancy, don't use medicinal amounts; safety hasn't been established.

During breastfeeding, the safety data is conflicting—limit use to food amounts and talk with your doctor or pharmacist about whether this supplement is right for you.

Side effects, ingredient by ingredient Horseradish

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Horseradish.
  • The most serious interaction on file is rated Moderate.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take thyroid hormone medication (including levothyroxine and other thyroid replacements), double-check with your doctor or pharmacist before using this product—horseradish may interfere with how your thyroid medication works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Horseradish supplements work best for people who want to try a traditional remedy but aren't taking thyroid hormone medication. If you take thyroid medication, check with your doctor or pharmacist before starting this product.

Because evidence for its effectiveness is limited and large amounts can cause digestive upset, it's worth a conversation with your healthcare provider about whether it makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Horseradish 450 mg 4:1 Extract, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064434274178
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 285787
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Horseradish 450 mg 4:1 Extract by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064434274178
IngredientAmount% DV
Horseradish Extract450 mg--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2020 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Horseradish 450 mg 4:1 Extract by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Horseradish 450 mg 4:1 Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Horseradish 450 mg 4:1 Extract by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Horseradish Extract

Interacts with
16 drugs
450 mg per serving

Horseradish is a pungent root used as a food and folk remedy, most often for sinus congestion and urinary tract complaints. Human evidence is limited,...

Horseradish Extract monograph & interactions

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Horseradish 450 mg 4:1 Extract by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Horseradish 450 mg 4:1 Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Moderate

Ingredients driving the most interactions

Horseradish Extract 16

Individual Drug Interactions

The ingredients in Horseradish 450 mg 4:1 Extract interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Horseradish 450 mg 4:1 Extract interact with drugs. Each result below shows which ingredient is responsible. Horseradish Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Horseradish 450 mg 4:1 Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Horseradish Extract1 drug type · 16 drugs

Thyroid Hormone

Theoretically, horseradish might interfere with the effects of thyroid hormone.
Horseradish and other members of the cabbage and mustard family are associated with depressed thyroid function.

Likelihood Possible Evidence D
Horseradish Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Horseradish 450 mg 4:1 Extract, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Horseradish 450 mg 4:1 Extract by TerraVita Premium Collection: Common Questions

Does Horseradish 450 mg 4:1 Extract by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Horseradish 450 mg 4:1 Extract has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Horseradish 450 mg 4:1 Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
No. Medicinal amounts of horseradish during pregnancy haven't been proven safe, so the data advises against it. Talk with your doctor about your options.
Is horseradish safe to use while breastfeeding?
The safety data is mixed. The safest approach is to stick to food amounts and talk with your doctor or pharmacist about whether a medicinal supplement makes sense for you right now.
What are the main side effects?
In food amounts, horseradish is generally well tolerated. Large doses can cause gastrointestinal upset, diarrhea, and irritation of mucous membranes. Rarely, it's been linked to fainting.
Does horseradish actually work for colds or UTIs?
We don't have enough reliable evidence to say whether it works for those conditions. That's something to discuss with your doctor if you're thinking about using it for a specific reason.
What's in the capsule besides the horseradish?
The capsule itself is made from gelatin and water—nothing else. These are the inactive ingredients that hold the extract together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Horseradish 450 mg 4:1 Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Horseradish 450 mg 4:1 Extract label
Go deeper

The Full Monographs Behind Horseradish 450 mg 4:1 Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Horseradish

Interacts with 16 drugs

Horseradish is a pungent root used as a food and folk remedy, most often for sinus congestion and urinary tract complaints. Human evidence is limited, and while culinary amounts are generall...

Read the full Horseradish monograph →
Sources

Sources & How We Checked

Horseradish 450 mg 4:1 Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Horseradish 6 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  5. Panter, K. E. and James, L. F. Natural plant toxicants in milk: a review. J Anim Sci 1990;68(3):892-904. PubMed
  6. Lehmann CU, Puckett AL, Betz BO. 56-year-old man - increased heart rate - weakness - intense sweating - horseradish consumption - Dx?. J Fam Pract 2022;71(7):317-321. PubMed

See these in context on the Horseradish monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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