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Dietary supplement

Horseradish Ingredients & Drug Interactions

by Herb Pharm

Horseradish label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Horseradish against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Horseradish is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for sinus and respiratory congestion, urinary tract infections, digestive support.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horseradish root (Armoracia rusticana) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Horseradish by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Horseradish by Herb Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Horseradish by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: horseradish root extract. Horseradish is a peppery root vegetable used traditionally to support respiratory health, digestion, and urinary tract function, though the evidence for these uses isn't well established.

The extract is preserved in certified organic cane alcohol and distilled water.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: respiratory system support.
  • We looked for evidence on: Respiratory tract infections, sinus congestion, bronchial health.
  • The closest evidence on file: Horseradish is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).

The evidence on horseradish for respiratory tract infections, intestinal parasites, urinary tract infections, and gout is insufficient — meaning the data we hold doesn't establish whether it works for these purposes. It's used in traditional herbalism for these conditions, but reliable clinical evidence is lacking.

The evidence, ingredient by ingredient Horseradish

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Horseradish in food amounts is generally well tolerated. At medicinal doses — especially in concentrated supplement form — it can irritate your digestive tract and mucous membranes.

Large amounts may cause gastrointestinal upset, diarrhea, or bloody vomiting, and in rare cases, a sudden drop in heart rate and blood pressure (vasovagal syncope) has been reported. During pregnancy, medicinal amounts should be avoided because safety hasn't been established.

During breastfeeding, the data is mixed and not well studied — stick to food amounts and talk with your doctor or pharmacist if you're considering taking a medicinal supplement while nursing.

Side effects, ingredient by ingredient Horseradish

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Horseradish.
  • The most serious interaction on file is rated Moderate.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take thyroid hormone replacement (levothyroxine, desiccated thyroid, or similar), check with your doctor or pharmacist before starting horseradish. The supplement may reduce how well your thyroid medication works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Horseradish is a traditional digestive and respiratory herb, but evidence for its effectiveness is limited. The main caution is for anyone on thyroid medication — you'll want to check with your doctor or pharmacist first because horseradish may interfere with how that drug works.

At food levels it's safe; at supplement doses, watch for stomach irritation. Pregnant women should avoid medicinal amounts.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Horseradish, straight from the product label.

Brand Herb Pharm
Barcode (UPC) 090700001681
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 220627
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Horseradish by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
0.7 mL
Servings per container
168
UPC/BARCODE
090700001681
IngredientAmount% DV
Horseradish root (Armoracia rusticana) extract670 mg--

Other ingredients: certified organic Cane Alcohol, distilled Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use Shake well before using Add 1 full squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 4 times per day. Best taken between meals.

Precautions

Keep out of the reach of children

Storage

Store away from heat & light

Formula

Armoracia rusticana

Horseradish liquid extract

We prepare our Horseradish extract from the root of certified organically grown Armoracia rusticana plants.

Formulation

Respiratory system

Gluten-free

Dry herb/menstruum ratio: 1:5

Certified organic by Organic Certifiers

Seals/Symbols

USDA Organic

FDA Statement of Identity

Herbal Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Horseradish by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Horseradish label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Horseradish by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container168 Amounts shown are per serving.

Horseradish root (Armoracia rusticana) extract

Interacts with
16 drugs
670 mg per serving

Horseradish is a pungent root used as a food and folk remedy, most often for sinus congestion and urinary tract complaints. Human evidence is limited,...

Horseradish root (Armoracia rusticana) extract monograph & interactions

Other (inactive) ingredients: Certified organic Cane Alcohol, Distilled Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Horseradish by Herb Pharm Drug Interactions

Want to check YOUR meds against Horseradish?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Moderate

Ingredients driving the most interactions

Horseradish root (Armoracia rusticana) extract 16

Individual Drug Interactions

The ingredients in Horseradish interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Horseradish interact with drugs. Each result below shows which ingredient is responsible. Horseradish root (Armoracia rusticana) extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Horseradish with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Horseradish root (Armoracia rusticana) extract1 drug type · 16 drugs

Thyroid Hormone

Theoretically, horseradish might interfere with the effects of thyroid hormone.
Horseradish and other members of the cabbage and mustard family are associated with depressed thyroid function.

Likelihood Possible Evidence D
Horseradish root (Armoracia rusticana) extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Horseradish, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Horseradish by Herb Pharm: Common Questions

Does Horseradish by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Horseradish has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Horseradish contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Medicinal amounts of horseradish aren't recommended during pregnancy because safety hasn't been established. Stick to food amounts — like a bit of horseradish sauce — and talk with your doctor or pharmacist if you're thinking of taking a supplement.
Is horseradish safe while breastfeeding?
Food amounts are likely safe, but the data on medicinal-dose supplements during breastfeeding isn't well studied. If you're nursing and considering this product, run it by your doctor or pharmacist first.
What are the main side effects?
In food amounts, it's generally well tolerated. At larger supplement doses, it can cause stomach upset, diarrhea, or digestive tract irritation. Rarely, consuming a lot of fresh horseradish has caused fainting due to a sudden drop in blood pressure.
Does horseradish actually work for respiratory infections or UTIs?
Horseradish is used traditionally for these conditions, but the reliable evidence isn't there yet. We don't have solid data showing it works.
What exactly is in this liquid?
It's horseradish root extract preserved in organic cane alcohol and distilled water — just the one active ingredient and those two preservatives, no fillers.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Horseradish is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Horseradish label
Go deeper

The Full Monographs Behind Horseradish’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Horseradish

Interacts with 16 drugs

Horseradish is a pungent root used as a food and folk remedy, most often for sinus congestion and urinary tract complaints. Human evidence is limited, and while culinary amounts are generall...

Read the full Horseradish monograph →
Sources

Sources & How We Checked

Horseradish's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Horseradish 6 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  5. Panter, K. E. and James, L. F. Natural plant toxicants in milk: a review. J Anim Sci 1990;68(3):892-904. PubMed
  6. Lehmann CU, Puckett AL, Betz BO. 56-year-old man - increased heart rate - weakness - intense sweating - horseradish consumption - Dx?. J Fam Pract 2022;71(7):317-321. PubMed

See these in context on the Horseradish monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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