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Dietary supplement

Hydrangea Root Extract Ingredients & Drug Interactions

by Christopher's Original Formulas

Hydrangea Root Extract label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hydrangea Root Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hydrangea Root Extract is a dietary supplement by Christopher's Original Formulas with 1 active ingredient. Its ingredients are commonly taken for kidney and bladder stones, urinary tract complaints, enlarged prostate symptoms.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are wildcrafted Hydrangea. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Hydrangea Root Extract by Christopher's Original Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Hydrangea Root Extract by Christopher's Original Formulas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Hydrangea Root Extract by Christopher's Original Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

This product contains one active ingredient: wildcrafted hydrangea root. Hydrangea is a plant traditionally used for certain urinary and kidney concerns, though we don't have effectiveness evidence on file for this product.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hydrangea product and its label doesn't state a use — see Hydrangea's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't hold effectiveness evidence for hydrangea root extract in our data.

The evidence, ingredient by ingredient Hydrangea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Human safety data for hydrangea are limited, and large or prolonged doses may cause unwanted effects. Orally, hydrangea may trigger gastroenteritis, dizziness, or a feeling of tightness in the chest.

The safety data advises against use during pregnancy and while breastfeeding due to insufficient information.

Side effects, ingredient by ingredient Hydrangea

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hydrangea.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this product if you take lithium (a mood stabilizer). Hydrangea's diuretic properties may increase lithium levels in your blood, which could require a dose adjustment.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Hydrangea Root Extract is worth discussing with your pharmacist if you're interested in traditional herbal support — but it's essential to check it against your medications, especially if you take lithium. Pregnant or breastfeeding?

Skip this one; the safety data aren't there yet.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hydrangea Root Extract, straight from the product label.

Brand Christopher's Original Formulas
Barcode (UPC) 084783498407
Net contents 2 fl. Oz.; 59 mL
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 200364
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hydrangea Root Extract by Christopher's Original Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Dropper(s)
Maximum serving Sizes:
1 Dropper(s)
Servings per container
60
UPC/BARCODE
084783498407
IngredientAmount% DV
Proprietary Blend0 NP--
wildcrafted Hydrangea0 NP--

Other ingredients: A base of

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 dropperful 3 times a day, or as directed by your health care professional.

Storage

Store in a cool dry place.

General Statements

Proudly Made In The U.S.A.

Brand IP Statement(s)

2017 Wholistic Botanicals L.L.C. All Rights Reserved

John R. Christopher

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hydrangea Root Extract by Christopher's Original Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hydrangea Root Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hydrangea Root Extract by Christopher's Original Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Dropper(s) Dosage formLiquid Servings per container60 Amounts shown are per serving.

Proprietary Blend

0 NP per serving

Other (inactive) ingredients: A base of. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hydrangea Root Extract by Christopher's Original Formulas Drug Interactions

Want to check YOUR meds against Hydrangea Root Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

wildcrafted Hydrangea 1

Individual Drug Interactions

The ingredients in Hydrangea Root Extract interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Hydrangea Root Extract interact with drugs. Each result below shows which ingredient is responsible. wildcrafted Hydrangea

Each ingredient & the kinds of drugs it affects

For each ingredient in Hydrangea Root Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

wildcrafted Hydrangea1 drug type · 1 drug

Lithium

Hydrangea is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, hydrangea might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
wildcrafted Hydrangea full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hydrangea Root Extract, from the product label.

Christopher's Original Formulas

See all Christopher's Original Formulas products
Name
Wholistic Botanicals L.L.C.
City
Spanish Fork
State
UT
ZipCode
84660
Phone Number
1-800-453-1406
Web Address
www.drchristopher.com
Pharmacist Counseling Corner

Hydrangea Root Extract by Christopher's Original Formulas: Common Questions

Does Hydrangea Root Extract by Christopher's Original Formulas interact with any medications?
Yes. Based on its ingredients, Hydrangea Root Extract has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hydrangea Root Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advise against it. There isn't enough information to know whether it's safe during pregnancy or while breastfeeding, so talk with your doctor or pharmacist for personalized advice.
What are the side effects?
Hydrangea may cause gastroenteritis (stomach upset), dizziness, or a feeling of tightness in the chest. Human safety data are limited, though, so large or prolonged doses could bring unwanted effects we don't know about yet.
Does this product have fillers?
Yes — it contains a base ingredient listed as inactive. The active ingredient is the wildcrafted hydrangea.
What is hydrangea used for?
Hydrangea is traditionally used in herbal medicine for urinary and kidney concerns. We don't have evidence data on file showing how well it works for any specific condition.
Is this safe if I take lithium?
Not without checking with your doctor or pharmacist first. Hydrangea's diuretic properties may increase lithium levels in your blood, which is a moderate-severity interaction that could require your dose to be adjusted.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hydrangea Root Extract label
Go deeper

The Full Monographs Behind Hydrangea Root Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hydrangea

Interacts with 1 drug

Hydrangea root has a long history in folk medicine, mainly for urinary and kidney stone complaints, but there is very little modern human research to confirm it works for any condition. Beca...

Read the full Hydrangea monograph →
Sources

Sources & How We Checked

Hydrangea Root Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hydrangea 1 reference
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

See these in context on the Hydrangea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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