Hydration Rescue Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Hydration Rescue against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hydration Rescue is a dietary supplement by NOW Solutions with 3 active ingredients. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Hydration Rescue by NOW Solutions
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Hydration Rescue contains three active ingredients. Two are hyaluronic acid—including a branded form called Hyabest—a naturally occurring substance your body uses to hold water and cushion joints and skin.
The third is hydrolyzed collagen (broken-down collagen protein), which supports skin structure. The capsule also holds inactive ingredients like microcrystalline cellulose, hypromellose, stearic acid, and silicon dioxide, which are binders and fillers that help form and stabilize the capsule.
Does it work?
Moderate evidence
Hyaluronic acid in this product is rated possibly effective for dry eye and venous leg ulcers (slow-healing wounds in the legs). For aging skin, allergic rhinitis (hay fever), and sexual dysfunction, the evidence isn't strong enough to rate it one way or the other.
We don't hold effectiveness data for hydrolyzed collagen in our system, so we can't speak to what research shows about its role in this formula.
How safe is it?
Well-documented data
Hyaluronic acid (the two forms here) is generally well tolerated when taken by mouth, though long-term safety of oral supplements hasn't been fully studied. The safety data available is limited, and medical guidance leans toward avoiding oral supplements unless your doctor has cleared it.
When applied to skin, it can occasionally cause eczema, redness, itching, or (rarely) wound infection. Eye drops with hyaluronic acid have rarely caused eye pain.
We don't have safety information on file for hydrolyzed collagen in this product.
Meds to double-check
No known interactions
No interactions are documented for the ingredients we could check in this product.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Hydration Rescue is a sensible choice if you're looking for hydration and skin-support ingredients with no documented medication interactions. Because long-term safety data on these oral supplements is incomplete and the evidence for aging skin is mixed, talk with your pharmacist or doctor about whether it fits your goals before you start, especially if you have any underlying health concerns.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hydration Rescue, straight from the product label.
| Brand | NOW Solutions |
|---|---|
| Barcode (UPC) | 733739033888 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 24, 2025 |
| DSLD ID | 335333 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hydration Rescue by NOW Solutions, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Hyaluronic Acid | 120 mg | -- |
| Hyabest Hyaluronic Acid | 120 mg | -- |
| Collagen, Hydrolyzed | 200 mg | -- |
Other ingredients: Hypromellose, Microcrystalline Cellulose, Stearic Acid, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Usage: Take 2 capsules daily.
Formula
Hyaluronic acid is a compound present in every tissue of the body, with the highest concentrations occurring in connective tissues such as skin and cartilage. Hyabest is a clinically validated form of hyaluronic acid that has been shown to preserve the skin's moisture and support its natural repair processes.
Hydration rescue with Hyabest hyaluronic acid
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Caution: For adults only.
Consult physician if pregnant/nursing, taking medication, or have a medical condition.
Keep out of reach of children.
Contains fish (cod, pollock, saithe, haddock, plaice) and wheat.
Not manufactured with soy, milk, egg, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Formulation
Natural color variation may occur in this product. EUA # 1482865
Helps maintain youthful looking skin Supports healthy skin moisture
Made and quality tested in the USA with globally sourced ingredients.
Not manufactured with soy, milk, egg, shellfish, tree nut or sesame ingredients.
Storage
Store in a cool, dry place after opening.
General Statements
This bottle is made from 100% PCR (post-consumer recycled) resin.
FDA Statement of Identity
A Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hydration Rescue by NOW Solutions label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hydration Rescue by NOW Solutions
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Hyaluronic Acid
No knowninteractions
Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...
Hyaluronic Acid monograph & interactionsHyabest Hyaluronic Acid
No knowninteractions
Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...
Hyabest Hyaluronic Acid monograph & interactionsCollagen, Hydrolyzed
Other (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Stearic Acid, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Hydration Rescue by NOW Solutions Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Hydration Rescue. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Hydration Rescue, from the product label.
NOW Solutions
See all NOW Solutions products- Name
- NOW Foods
- Street Address
- 395 S. Glen Ellyn Rd.
- City
- Bloomingdale
- State
- IL
- ZipCode
- 60108
- Web Address
- nowfoods.com
Hydration Rescue by NOW Solutions: Common Questions
Does Hydration Rescue by NOW Solutions interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does hyaluronic acid actually help dry eyes?
Will this help my aging skin?
What's hydrolyzed collagen, and why is it in here?
Are there any side effects I should know about?
Is it safe to take this long-term?
Can I take this while pregnant or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hydration Rescue is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hydration Rescue’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Hydration Rescue's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hyaluronic Acid 4 references
- Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
- U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
- Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
- Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC