Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

Aquatic Beauty Ingredients & Drug Interactions

by NOW Solutions

Aquatic Beauty label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Aquatic Beauty against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Aquatic Beauty is a dietary supplement by NOW Solutions with 5 active ingredients. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.Based on those ingredients, 782 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are AstaReal, Vitamin C. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Aquatic Beauty by NOW Solutions

Ask about any prescription or over-the-counter medication and we check it for interactions with Aquatic Beauty by NOW Solutions — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Aquatic Beauty by NOW Solutions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Aquatic Beauty is a powder with four active ingredients. Hyaluronic Acid is a natural compound that holds water in skin and may help with dry eyes and certain types of wounds.

Vitamin C (ascorbic acid) is an essential nutrient that supports collagen formation and immune function. AstaReal is astaxanthin, a carotenoid antioxidant derived from algae.

Hydrolyzed Collagen is a breakdown product of collagen protein. The powder also contains silicon dioxide as an inactive ingredient.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Skin health, moisture and youthful appearance.
  • We looked for evidence on: Aging skin, Dry eye, Skin elasticity, Skin tone, Skin texture.
  • The strongest evidence on file: Hyaluronic Acid is rated "Possibly Effective" for Dry eye (Natural Medicines).
  • Also on file: Vitamin C is rated "Insufficient Reliable Evidence To Rate" for Aging skin.
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Aging skin.

The evidence we hold is mixed and sparse. Hyaluronic Acid is possibly effective for dry eyes and venous leg ulcers (slow-healing wounds on the legs), but evidence is insufficient to rate it for aging skin or allergic rhinitis.

Vitamin C is effective for preventing vitamin C deficiency and is possibly effective for certain types of anemia, atrial fibrillation, cataracts, and respiratory infections triggered by intense exercise. For astaxanthin (AstaReal), the evidence we have does not establish effectiveness for age-related cognitive decline, macular degeneration, aging skin, Alzheimer disease, athletic performance, or carpal tunnel syndrome.

We hold no effectiveness data for Hydrolyzed Collagen.

The evidence, ingredient by ingredient Hyaluronic Acid Vitamin C Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hyaluronic Acid is generally well tolerated when taken by mouth or applied to skin, though topical use can occasionally cause eczema, redness, itching, bleeding, or infection. Safety data for oral supplements are not fully studied long-term.

Vitamin C is safe at normal dietary and supplement doses but can cause abdominal cramps, heartburn, diarrhea, nausea, and headache at high doses above 2 grams daily; kidney stones are rare but possible in people prone to them. Astaxanthin (AstaReal) is generally well tolerated in studies, though higher doses have caused abdominal pain and changes in bowel movements.

We hold no safety information for Hydrolyzed Collagen. For pregnancy and breastfeeding: Vitamin C at normal recommended amounts is likely safe, but high-dose supplements should be avoided unless your doctor advises otherwise.

Astaxanthin data are insufficient to confirm safety, so it is best to avoid it during pregnancy and breastfeeding. We have no pregnancy/breastfeeding data on file for Hyaluronic Acid or Hydrolyzed Collagen—talk with your doctor or pharmacist before use if you are pregnant or nursing.

Side effects, ingredient by ingredient Hyaluronic Acid Vitamin C Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Vitamin C, Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; cancer treatments.
  • For scale: 783 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Aquatic Beauty, check the following medication types with your pharmacist: blood thinners like warfarin (Moderate severity—high-dose vitamin C may reduce effectiveness); oral contraceptives and hormone replacement therapy (Moderate—vitamin C may increase estrogen levels); chemotherapy drugs, particularly alkylating agents and antitumor antibiotics (Moderate—vitamin C's antioxidant action might interfere); fluphenazine and other antipsychotics (Moderate); antiretrovirals like indinavir (Moderate); levothyroxine and other thyroid medications (Moderate); and drugs metabolized by liver enzymes CYP3A4 or CYP2B6 (Moderate—astaxanthin may lower their levels). Additionally, aluminum-containing products like some antacids may have increased absorption with vitamin C.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is most useful if you're looking to support dry eyes or skin hydration, and Vitamin C adds antioxidant support. However, if you take warfarin or other blood thinners, hormone contraceptives, chemotherapy, thyroid medication, or certain psychiatric or antiviral drugs, check with your pharmacist before starting—Vitamin C can change how these work.

Pregnant or breastfeeding? Talk to your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Aquatic Beauty, straight from the product label.

Brand NOW Solutions
Barcode (UPC) 733739033932
Net contents 3 Ounce(s); 85 Gram(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 314231
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Aquatic Beauty by NOW Solutions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3.2 Gram(s)
Maximum serving Sizes:
3.2 Gram(s)
Servings per container
27
UPC/BARCODE
733739033932
IngredientAmount% DV
Protein2 Gram(s)--
Calories10 Calorie(s)--
Hyaluronic Acid120 mg--
Vitamin C100 mg111%
AstaReal3 mg--
Collagen, Hydrolyzed2000 mg--

Other ingredients: Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Add 1/2 level tablespoon daily to 8 oz. of water, favorite beverage or smoothie (works great with citrus flavor). Vigorously mixed in shaker cup or blender.

Shake with water or blend into smoothies

Formula

Now Solutions Aquatic Beauty features wild-caught fish collagen and astaxanthin, which has been found in clinical studies to maintain youthful skin moisture and texture and promote even skin tone. This product also includes vitamin C and hyaluronic acid, a compound found naturally in skin with a unique capacity to bind and retain water molecules.

Marine collagen + astaxanthin powder

Marine collagen from wild-caught fish

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: For adults only. Keep out of reach of children.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Do not eat freshness packets enclosed.

Not manufactured with wheat, gluten, soy, milk, egg, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation

Natural color variation may occur in this product.

Promotes youthful skin texture and tone Moisturizes from within

Non-GMO

Made and quality tested in the USA with globally sourced ingredients.

Not manufactured with wheat, gluten, soy, milk, egg, shellfish, tree nut or sesame ingredients.

Radiant skin Moisturizes from within

Storage

This product is sold by weight not volume. Store in a cool, dry place after opening.

Brand IP Statement(s)

AstaReal is a registered trademark of Fuji Chemical Industries Co., Ltd.

General Statements

EUA# 1482865

FDA Statement of Identity

A Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Aquatic Beauty by NOW Solutions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Aquatic Beauty label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Aquatic Beauty by NOW Solutions

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size3.2 Gram(s) Dosage formPowder Servings per container27 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

2 Gram(s) per serving

Hyaluronic Acid

No known
interactions
120 mg per serving Form: Sodium Hyaluronate

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

Hyaluronic Acid monograph & interactions

Vitamin C

Interacts with
207 drugs
100 mg per serving Form: Sodium Ascorbate

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...

Vitamin C monograph & interactions

AstaReal

Interacts with
671 drugs
3 mg per serving Form: Astaxanthin

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

AstaReal monograph & interactions

Collagen, Hydrolyzed

2000 mg per serving Form: Fish

Other (inactive) ingredients: Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Aquatic Beauty by NOW Solutions Drug Interactions

Want to check YOUR meds against Aquatic Beauty?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
782Drugs
726 Moderate 56 Minor

Ingredients driving the most interactions

AstaReal 671
Vitamin C 207

Individual Drug Interactions

The ingredients in Aquatic Beauty interact with 782 drugs. Click any drug to see the details.

2 of the 5 ingredients in Aquatic Beauty interact with drugs. Each result below shows which ingredient is responsible. AstaReal Vitamin C

Each ingredient & the kinds of drugs it affects

For each ingredient in Aquatic Beauty with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

AstaReal2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
AstaReal full monograph & interactions

Vitamin C13 drug types · 207 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Aluminum

Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.

Likelihood Probable Evidence B
Antitumor Antibiotics

Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Estrogens

Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.

Likelihood Probable Evidence B
Fluphenazine (Prolixin)

Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.

Likelihood Possible Evidence D
Indinavir (Crixivan)

Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.

Likelihood Probable Evidence B
Warfarin (Coumadin)

High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.

Likelihood Probable Evidence B
Aspirin

Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.

Likelihood Possible Evidence B
Choline Magnesium Trisalicylate (Trilisate)

Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Niacin

Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Salsalate (Disalcid)

Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Vitamin C full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Aquatic Beauty, from the product label.

NOW Solutions

See all NOW Solutions products
Name
Now Foods
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com/nowsolutions
Pharmacist Counseling Corner

Aquatic Beauty by NOW Solutions: Common Questions

Does Aquatic Beauty by NOW Solutions interact with any medications?
Yes. Based on its ingredients, Aquatic Beauty has a known interaction with 782 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Aquatic Beauty contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is hyaluronic acid, and why is it in this product?
Hyaluronic acid is a natural substance that holds water and is found in skin and joints. In this product, it's included because it may help with dry eyes and skin hydration, and shows some promise for healing certain types of wounds.
Is this safe to take if I'm pregnant or breastfeeding?
Vitamin C at normal recommended doses is likely safe in pregnancy, but high-dose supplements should be avoided unless your doctor says it's okay. Astaxanthin (AstaReal) doesn't have enough safety data, so it's best to avoid it during pregnancy and breastfeeding. We don't have pregnancy/breastfeeding information for the other ingredients—ask your doctor or pharmacist for personalized advice.
Can vitamin C in this powder cause kidney stones?
Kidney stones are rare but have been reported in people prone to them who take high-dose vitamin C supplements. Since this is a powder, the amount per serving matters; check the label and talk to your pharmacist if you have a history of kidney stones.
What are the most common side effects?
Vitamin C at high doses can cause abdominal cramps, heartburn, diarrhea, and nausea. Astaxanthin may cause abdominal pain, diarrhea, or red-colored stools in some people. Hyaluronic acid is generally well tolerated by mouth, though topical application can rarely cause itching or redness.
Will this help my aging skin?
We don't have strong evidence that the ingredients in this product improve aging skin. Hyaluronic acid shows promise for skin hydration, but the evidence isn't established. Talk to your pharmacist or dermatologist about what the science supports for your specific skin goals.
Does this product contain any fillers or other ingredients besides the active ones?
Yes, it contains silicon dioxide as an inactive ingredient in addition to the four active ingredients listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Aquatic Beauty label
Go deeper

The Full Monographs Behind Aquatic Beauty’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hyaluronic Acid

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin moisture and joint comfort, and the evi...

Read the full Hyaluronic Acid monograph → Herb & supplement monograph

Vitamin C

Interacts with 207 drugs

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...

Read the full Vitamin C monograph → Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Aquatic Beauty's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 58 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Vitamin C 51 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
  3. Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
  4. Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
  5. Dwyer JH, Merz NB, Shirocre AM, et al. Progression of early atherosclerosis and intake of vitamin C and vitamin E from supplements and food. The Los Angeles Atherosclerosis Study. 41st Annual Conference on Cardiovascular Disease Epidemiology and Prevent
  6. Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA 1999;281:1415-23. PubMed
  7. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  8. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  9. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
  10. Houston JB, Levy G. Drug biotransformation interactions in man VI: Acetaminophen and ascorbic acid. J Pharm Sci 1976;65:1218-21. PubMed
  11. Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
  12. Rosenthal G. Interaction of ascorbic acid and warfarin. JAMA 1971;215:1671. DOI
  13. Hume R, Johnstone JM, Weyers E. Interaction of ascorbic acid and warfarin. JAMA 1972;219:1479. DOI
  14. Smith EC, Skalski RJ, Johnson GC, Rossi GV. Interaction of ascorbic acid and warfarin. JAMA 1972;221:1166. DOI
  15. Traxer O, Huet B, Poindexter J, et al. Effect of ascorbic acid consumption on urinary stone risk factors. J Urol 2003;170:397-401.. PubMed
  16. Domingo JL, Gomez M, Llobet JM, Richart C. Effect of ascorbic acid on gastrointestinal aluminum absorption (letter). Lancet 1991;338:1467.
  17. Domingo JL, Gomez M, Llobet JM, Corbella J. Influence of some dietary constituents on aluminum absorption and retention in rats. Kidney Int 1991;39:598-601. PubMed
  18. Partridge NA, Regnier FE, White JL, Hem SL. Influence of dietary constituents on intestinal absorption of aluminum. Kidney Int 1989;35:1413-7. PubMed
  19. Mc Leod DC, Nahata MC. Inefficacy of ascorbic acid as a urinary acidifier (letter). N Engl J Med 1977;296:1413. DOI
  20. Hansten PD, Hayton WL. Effect of antacid and ascorbic acid on serum salicylate concentration. J Clin Pharmacol 1980;20:326-31. PubMed
  21. Dysken MW, Cumming RJ, Channon RA, Davis JM. Drug interaction between ascorbic acid and fluphenazine. JAMA 1979;241:2008. DOI
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See these in context on the Vitamin C monograph →

Astaxanthin 3 references
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See these in context on the Astaxanthin monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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