Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Kidney Flush Ingredients & Drug Interactions

by Chief Originals

Kidney Flush label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kidney Flush against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Kidney Flush is a dietary supplement by Chief Originals with 4 active ingredients. Its ingredients are commonly taken for cough and sore throat, dry mouth and throat irritation, digestive upset and heartburn.Based on those ingredients, 2,040 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marshmallow, Hydrangea. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Kidney Flush by Chief Originals

Ask about any prescription or over-the-counter medication and we check it for interactions with Kidney Flush by Chief Originals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Kidney Flush by Chief Originals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.

Kidney Flush contains 4 active ingredients: marshmallow, hydrangea, gravel, and stone root. The product is formulated as a liquid extract blended with distilled water, organic sugar cane alcohol, and vegetable glycerin as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The effectiveness data we hold shows insufficient reliable evidence to rate marshmallow for any of the conditions studied — including vaginal yeast infections, diarrhea, leg ulcers, eczema, and respiratory infections. No effectiveness ratings are on file for hydrangea, gravel, or stone root in our data.

The evidence, ingredient by ingredient Marshmallow Hydrangea Stone Root

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Marshmallow is generally well tolerated for short-term use, though human safety data are limited. Hydrangea may cause gastroenteritis, dizziness, or a feeling of tightness in the chest, and large or prolonged doses could cause unwanted effects.

Stone root in large amounts can cause intestinal irritation, cramping, dizziness, and nausea. Regarding pregnancy: the safety data advise against marshmallow and hydrangea during pregnancy, and against them while breastfeeding as well.

For stone root, there isn't enough data to know either way — talk with your doctor or pharmacist about it if you're pregnant or nursing.

Side effects, ingredient by ingredient Marshmallow Hydrangea Stone Root

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Hydrangea, Marshmallow.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; lithium.
  • For scale: 2,041 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Kidney Flush, double-check with your doctor or pharmacist if you take lithium — both marshmallow and hydrangea may raise its levels to unsafe amounts. Also check any other oral medications, since marshmallow may reduce how well you absorb them; spacing doses 30 to 60 minutes apart can help.

Let them know if you take blood thinners (anticoagulants) or antiplatelet drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Kidney Flush is a four-ingredient herbal blend with limited human safety data and no established effectiveness for the conditions it may target. The biggest concern is its potential to raise lithium levels dangerously, and a secondary concern is interference with oral medication absorption.

If you take lithium, any prescription medications, or blood thinners, check your exact drugs with your pharmacist or doctor before starting this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kidney Flush, straight from the product label.

Brand Chief Originals
Barcode (UPC) 050742582999
Net contents 2 Fluid Ounce(s); 59 mL
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 250739
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kidney Flush by Chief Originals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Dropperful(s)
Maximum serving Sizes:
2 Dropperful(s)
UPC/BARCODE
050742582999
IngredientAmount% DV
Marshmallow0 NP--
Hydrangea0 NP--
Gravel0 NP--
Stone Root0 NP--

Other ingredients: distilled Water, organic Sugar Cane Alcohol, Vegetable Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

This quick-to-absorb, soothing formula supporst healthy kidney function.

Made in the USA with worldwide ingredients

Herbal extract

Formula

Kidney Flush Herbal Extract features the liquid extracts of Stone root, Gravel root and moch more.

Suggested/Recommended/Usage/Directions

Instructions: 1-2 dropperfuls in water or juice three to four times daily or as directed by your health practitioner.

Shake well before use

Precautions

Do not use if tamper evident seal is broken

Keep out of reach of children.

FDA Statement of Identity

Herbal Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to treat, cure or diagnose any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kidney Flush by Chief Originals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kidney Flush label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kidney Flush by Chief Originals

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Dropperful(s) Dosage formLiquid Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Marshmallow

Interacts with
2,040 drugs
0 NP per serving

Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats,...

Marshmallow monograph & interactions

Hydrangea

Interacts with
1 drug
0 NP per serving

Hydrangea root has a long history in folk medicine, mainly for urinary and kidney stone complaints, but there is very little modern human research to...

Hydrangea monograph & interactions

Gravel

0 NP per serving

Stone Root

No known
interactions
0 NP per serving

Stone root is a North American herb traditionally used for hemorrhoids, urinary complaints, and digestive issues. There is very little modern scientif...

Stone Root monograph & interactions

Other (inactive) ingredients: Distilled Water, Organic Sugar Cane Alcohol, Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kidney Flush by Chief Originals Drug Interactions

Want to check YOUR meds against Kidney Flush?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,040Drugs
1 Moderate 2,039 Minor

Ingredients driving the most interactions

Marshmallow 2,040
Hydrangea 1

Individual Drug Interactions

The ingredients in Kidney Flush interact with 2,040 drugs. Click any drug to see the details.

2 of the 4 ingredients in Kidney Flush interact with drugs. Each result below shows which ingredient is responsible. Marshmallow Hydrangea

Each ingredient & the kinds of drugs it affects

For each ingredient in Kidney Flush with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Marshmallow3 drug types · 2,040 drugs

Lithium

Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.

Likelihood Possible Evidence D
Marshmallow full monograph & interactions

Hydrangea1 drug type · 1 drug

Lithium

Hydrangea is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, hydrangea might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Hydrangea full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kidney Flush, from the product label.

Chief Originals

See all Chief Originals products
Name
Chief Originals
Pharmacist Counseling Corner

Kidney Flush by Chief Originals: Common Questions

Does Kidney Flush by Chief Originals interact with any medications?
Yes. Based on its ingredients, Kidney Flush has a known interaction with 2,040 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kidney Flush contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take Kidney Flush while pregnant?
No — the safety data advise against marshmallow and hydrangea during pregnancy. There's not enough information on gravel or stone root to say either way. Talk with your doctor or pharmacist about whether this product is right for you.
Can I take Kidney Flush while breastfeeding?
The safety data advise against both marshmallow and hydrangea while breastfeeding. For stone root, there's not enough data to know either way. Gravel has no safety data on file. Check with your doctor or pharmacist before using this product.
What's marshmallow actually used for in supplements?
Marshmallow root and leaf are traditionally used for soothing, though our data show insufficient evidence to rate it for specific conditions like diarrhea, respiratory infections, or skin issues like eczema.
Can marshmallow interfere with my other medicines?
Yes — marshmallow's mucilage can reduce how well your body absorbs oral medications. To minimize this, take the supplement 30 to 60 minutes after your other drugs.
What side effects might hydrangea cause?
Hydrangea may cause gastroenteritis, dizziness, or a tight feeling in the chest. Large or prolonged doses could cause additional unwanted effects, so use with care.
What happens if I take this with lithium?
Both marshmallow and hydrangea have diuretic properties that may slow how your body clears lithium, raising its levels and risking toxicity. Your doctor may need to lower your lithium dose — don't adjust it yourself, and talk with them before adding this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Kidney Flush is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kidney Flush label
Go deeper

The Full Monographs Behind Kidney Flush’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Marshmallow

Interacts with 2,040 drugs

Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...

Read the full Marshmallow monograph → Herb & supplement monograph

Hydrangea

Interacts with 1 drug

Hydrangea root has a long history in folk medicine, mainly for urinary and kidney stone complaints, but there is very little modern human research to confirm it works for any condition. Beca...

Read the full Hydrangea monograph → Herb & supplement monograph

Stone Root

Stone root is a North American herb traditionally used for hemorrhoids, urinary complaints, and digestive issues. There is very little modern scientific evidence to confirm it works for any...

Read the full Stone Root monograph →
Sources

Sources & How We Checked

Kidney Flush's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Marshmallow 5 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Hage-Sleiman R, Mroueh M, Daher CF. Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon. Pharm Biol 2011;49(3):327-33.

See these in context on the Marshmallow monograph →

Hydrangea 1 reference
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

See these in context on the Hydrangea monograph →

Stone Root 1 reference
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

See these in context on the Stone Root monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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