Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Kids Probiotic + Prebiotic Just Peach Ingredients & Drug Interactions

by OLLY

Kids Probiotic + Prebiotic Just Peach label
See full label image
Gummy Or Jelly Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kids Probiotic + Prebiotic Just Peach against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Kids Probiotic + Prebiotic Just Peach is a dietary supplement by OLLY with 4 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,142 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Peppermint extract, Bacillus coagulans MTCC 5856. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Kids Probiotic + Prebiotic Just Peach by OLLY

Ask about any prescription or over-the-counter medication and we check it for interactions with Kids Probiotic + Prebiotic Just Peach by OLLY — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Kids Probiotic + Prebiotic Just Peach by OLLY

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 3 of its 4 active ingredients.

This product has 3 active ingredients. Peppermint extract is included for digestive comfort — it's traditionally used to ease cramping and bloating.

Bacillus coagulans MTCC 5856 is a beneficial live bacterium (probiotic) that helps keep the gut environment balanced. FOS is a prebiotic fiber that feeds the good bacteria in your child's digestive system, helping them thrive.

Together, they're meant to support healthy digestion and gut function in kids. The gummy also contains inactive ingredients like gelatin, cane sugar, glucose syrup, and natural flavors — the stuff that makes it taste good and hold together, plus water and small amounts of lactic acid and citric acid for preservation.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: digestive health and balance in children.
  • We looked for evidence on: Abdominal pain, Constipation, Diarrhea, Dyspepsia, Flatulence, Irritable bowel syndrome (IBS) — and 2 related terms.
  • The strongest evidence on file: Black Psyllium is rated "Effective" for Constipation (Natural Medicines).
  • Also on file: Peppermint is rated "Likely Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Peppermint is rated "Possibly Effective" for Dyspepsia.

Peppermint extract is likely effective for irritable bowel syndrome (IBS) and possibly effective for general indigestion, nausea from chemotherapy, and easing colonic spasms. Bacillus coagulans is possibly effective for constipation and IBS, but the evidence for antibiotic-associated diarrhea, athletic performance, cancer support, and fatty liver disease isn't yet reliable enough to rate.

FOS — we don't have effectiveness data on file for this ingredient.

The evidence, ingredient by ingredient Black Psyllium Peppermint Bacillus Coagulans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Peppermint extract in food and tea amounts is generally well tolerated, but concentrated oils and supplements should be used carefully and ideally approved by your child's doctor first. The most common side effects from oral peppermint are mild — abdominal pain, belching, diarrhea, dry mouth, heartburn, nausea, and vomiting — though severe reactions like allergic swelling of the lips and throat are rare.

Bacillus coagulans is generally well tolerated in healthy kids, though safety evidence is limited and product quality can vary. One concern with any probiotic is that in rare cases, the live organisms could cause infection in very ill or severely immunocompromised children, but this risk is small in healthy kids with normal immune systems.

Side effects, ingredient by ingredient Black Psyllium Peppermint Bacillus Coagulans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Black Psyllium, Peppermint, Bacillus Coagulans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; heart-rhythm medications; lithium.
  • For scale: 2,143 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if your child takes antibiotics (the probiotic works best when spaced apart from them), or any medications metabolized by liver enzymes CYP2C19, CYP2C9, or CYP3A4 — including certain heart medications and immunosuppressants. The peppermint extract can theoretically raise the levels of these drugs, though this hasn't been reported in humans yet.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

OLLY Kids Probiotic + Prebiotic Just Peach may help support your child's digestion and gut balance, especially if they have constipation or cramping. Before starting it, check with your pharmacist if your child takes antibiotics — they'll need to be timed separately — or if they're on medications metabolized by the liver, particularly immunosuppressants or heart drugs.

The peppermint extract is in a gummy form rather than concentrated oil, which is safer for kids.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kids Probiotic + Prebiotic Just Peach, straight from the product label.

Brand OLLY
Barcode (UPC) 858158005435
Net contents 30 Gummy(ies)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 230231
Product type Other Combinations
Supplement form Gummy Or Jelly
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Gluten Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kids Probiotic + Prebiotic Just Peach by OLLY, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gummy(ies)
Maximum serving Sizes:
1 Gummy(ies)
Servings per container
30
UPC/BARCODE
858158005435
IngredientAmount% DV
Calories5 Calorie(s)--
Total Carbohydrates2 Gram(s)1%, 1%
Dietary Fiber1 Gram(s)7%, 4%
Added Sugars1 Gram(s)4%, 2%
Total Sugars1 Gram(s)--
FOS1.1 Gram(s)--
Peppermint extract18 mg--
Bacillus coagulans MTCC 58560 NP--

Other ingredients: Water, Cane Sugar, Gelatin, Glucose Syrup, Lactic Acid, Citric Acid, Natural flavor, Coloring

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

The Goods Inside Probiotic A super boost of the good bugs to help keep little digestive systems in balance. Prebiotic Probiotic's best buddy - this healthy fiber helps build the good guys' team. Game on! Peppermint This soothing botanical is traditionally used to calm little tummies.

Just Peachy With other Natural Flavors

Live cultures, friendly fiber & peppermint

General Statements

Find your Olly at Olly.com Facebook Olly Instagram Pinterest Twitter @Ollynutrition

Formulation

For a happy tummy

No artificial flavors or colors Gluten free

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Ages 2 and up, take 1 gummy daily. Chew thoroughly before swallowing. No food or water needed.

Take only as directed. Do not exceed suggested dosage.

Precautions

Processed in a facility with products that may contain soy, egg, peanuts, tree nuts, milk, fish, shellfish and wheat.

Do not exceed suggested dosage.

If you have a medical condition, are on medication or are pregnant or nursing, please seek the advice of a qualified health care professional before using.

Do not use if inner seal is broken or missing.

Keep out of the reach of children

Storage

Store in a cool, dry place.

Seals/Symbols

Certified B Corporation Contents Certified NSF

Brand IP Statement(s)

2019 OLLY PBC

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kids Probiotic + Prebiotic Just Peach by OLLY label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kids Probiotic + Prebiotic Just Peach label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kids Probiotic + Prebiotic Just Peach by OLLY

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
1 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

FOS

1.1 Gram(s) per serving

Peppermint extract

Interacts with
796 drugs
18 mg per serving

Peppermint is a popular herb with the best evidence supporting enteric-coated peppermint oil for easing IBS symptoms. It is generally well tolerated f...

Peppermint extract monograph & interactions

Bacillus coagulans MTCC 5856

Interacts with
182 drugs
0 NP per serving

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...

Bacillus coagulans MTCC 5856 monograph & interactions

Other (inactive) ingredients: Water, Cane Sugar, Gelatin, Glucose Syrup, Lactic Acid, Citric Acid, Natural flavor, Coloring. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kids Probiotic + Prebiotic Just Peach by OLLY Drug Interactions

Want to check YOUR meds against Kids Probiotic + Prebiotic Just Peach?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,142Drugs
909 Moderate 1,233 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Peppermint extract 796
Bacillus coagulans MTCC 5856 182

Individual Drug Interactions

The ingredients in Kids Probiotic + Prebiotic Just Peach interact with 2,142 drugs. Click any drug to see the details.

3 of the 4 ingredients in Kids Probiotic + Prebiotic Just Peach interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Peppermint extract Bacillus coagulans MTCC 5856

Each ingredient & the kinds of drugs it affects

For each ingredient in Kids Probiotic + Prebiotic Just Peach with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Peppermint extract5 drug types · 796 drugs

Cyclosporine (Neoral, Sandimmune)

Theoretically, peppermint oil might increase the levels and adverse effects of cyclosporine.
In animal research, peppermint oil inhibits cyclosporine metabolism and increases cyclosporine levels. Inhibition of cytochrome P450 3A4 (CYP3A4) may be partially responsible for this interaction. An interaction between peppermint oil and cyclosporine has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, peppermint might increase the levels of CYP2C19 substrates.
In vitro research shows that peppermint oil inhibits CYP2C19. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, peppermint might increase the levels of CYP2C9 substrates.
In vitro research shows that peppermint oil inhibits CYP2C9. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Clinical research in healthy volunteers shows that a single dose of peppermint oil 600 mg inhibits CYP3A4 enzymes and increases the AUC of felodipine, a CYP3A4 substrate. However, in vitro research suggests that peppermint oil only inhibits CYP3A4 at very high concentrations.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, peppermint might increase the levels of CYP1A2 substrates.
In vitro and animal research shows that peppermint oil and peppermint leaf inhibit CYP1A2. However, in clinical research, peppermint tea did not significantly affect the metabolism of caffeine, a CYP1A2 substrate. It is possible that the 6-day duration of treatment may have been too short to identify a difference.

Likelihood Possible Evidence B
Peppermint extract full monograph & interactions

Bacillus coagulans MTCC 58561 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
Bacillus coagulans MTCC 5856 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kids Probiotic + Prebiotic Just Peach, from the product label.

OLLY

See all OLLY products
Name
OLLY Public Benefit Corp.
City
San Francisco
State
CA
ZipCode
94111
Phone Number
1-844-439-6559
Web Address
OLLY.com
Pharmacist Counseling Corner

Kids Probiotic + Prebiotic Just Peach by OLLY: Common Questions

Does Kids Probiotic + Prebiotic Just Peach by OLLY interact with any medications?
Yes. Based on its ingredients, Kids Probiotic + Prebiotic Just Peach has a known interaction with 2,142 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kids Probiotic + Prebiotic Just Peach contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is peppermint safe for kids?
Peppermint in food and tea amounts is generally safe for children. This gummy contains peppermint extract rather than concentrated oil, which is the safer form. That said, concentrated peppermint supplements should be used only with your child's doctor's approval.
Can my child take this with antibiotics?
Not at the same time. Antibiotics can kill the live Bacillus coagulans organisms in the probiotic. Ask your pharmacist how to space them apart — usually a few hours between doses works.
What does the prebiotic (FOS) do?
FOS is a type of fiber that feeds the good bacteria (like Bacillus coagulans) already in your child's gut, helping them grow and thrive. It's meant to work together with the probiotic.
What are the most common side effects?
Peppermint can cause mild digestive upset — belly pain, belching, diarrhea, dry mouth, heartburn, nausea — though most kids tolerate it well. Serious allergic reactions are very rare.
Is this okay during pregnancy or breastfeeding?
The peppermint extract is rated likely safe during pregnancy and lactation. We don't have pregnancy or lactation safety information on file for Bacillus coagulans, so check with your doctor or pharmacist before using it while pregnant or nursing.
Does this gummy actually work for constipation or IBS?
Peppermint is likely effective for IBS and both ingredients are possibly effective for constipation. But results vary from child to child, and it's not a quick fix — it works best as part of a healthy diet with plenty of fluids and fiber.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kids Probiotic + Prebiotic Just Peach label
Go deeper

The Full Monographs Behind Kids Probiotic + Prebiotic Just Peach’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Peppermint

Interacts with 796 drugs

Peppermint is a popular herb with the best evidence supporting enteric-coated peppermint oil for easing IBS symptoms. It is generally well tolerated for most adults, but it can cause heartbu...

Read the full Peppermint monograph → Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph →
Sources

Sources & How We Checked

Kids Probiotic + Prebiotic Just Peach's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 79 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Peppermint 41 references
  1. Liu JH, Chen GH, Yeh HZ, et al. Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial. J Gastroenterol 1997;32:765-8. PubMed
  2. Pittler MH, Ernst E. Peppermint oil for irritable bowel syndrome: a critical review and metaanalysis. Am J Gastroenterol 1998;93:1131-5. PubMed
  3. Kline RM, Kline JJ, Di Palma J, Barbero GJ. Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. J Pediatr 2001;138:125-8. PubMed
  4. Madisch A, Heydenreich CJ, Wieland V, et al. Treatment of functional dyspepsia with a fixed peppermint oil and caraway oil combination preparation as compared to cisapride. A multicenter, reference-controlled, double-blind equivalence study. Arzneimittel
  5. May B, Kuntz HD, Kieser M, Kohler S. Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia. Arzneimittelforschung 1996;46:1149-53.
  6. Micklefield GH, Greving I, May B. Effects of peppermint oil and caraway oil on gastroduodenal motility. Phytother Res 2000;14:20-3. DOI
  7. Morton CA, Garioch J, Todd P, et al. Contact sensitivity to menthol and peppermint in patients with intra-oral symptoms. Contact Dermatitis 1995;32:281-4. PubMed
  8. May B, Kohler S, Schneider B. Efficacy and tolerability of a fixed combination of peppermint oil and caraway oil in patients suffering from functional dyspepsia. Aliment Pharmacol Ther 2000;14:1671-7. PubMed
  9. Nash P, Gould SR, Bernardo DE. Peppermint oil does not relieve the pain of irritable bowel syndrome. Br J Clin Pract 1986;40:292-3. DOI
  10. Rees WD, Evans BK, Rhodes J. Treating irritable bowel syndrome with peppermint oil. Br Med J 1979;2:835-6. PubMed
  11. Davies SJ, Harding LM, Baranowski AP. A novel treatment of postherpetic neuralgia using peppermint oil. Clin J Pain 2002;18:200-2. PubMed
  12. Weston CF. Anal burning and peppermint oil. Postgrad Med J 1987;63:717. PubMed
  13. Dresser GK, Wacher V, Wong S, et al. Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo. Clin Pharmacol Ther 2002;72:247-55. PubMed
  14. Wacher VJ, Wong S, Wong HT. Peppermint oil enhances cyclosporine oral bioavailability in rats: comparison with D-alpha-tocopheryl poly(ethylene glycol 1000) succinate (TPGS) and ketoconazole. J Pharm Sci 2002;91:77-90.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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