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Dietary supplement

Krill Oil Gold 500 mg Ingredients & Drug Interactions

by NutriGold

Krill Oil Gold 500 mg label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Krill Oil Gold 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Krill Oil Gold 500 mg is a dietary supplement by NutriGold with 1 active ingredient. Its ingredients are commonly taken for heart and cholesterol support, high triglycerides, joint pain and inflammation.Based on those ingredients, 838 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Krill Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Krill Oil Gold 500 mg by NutriGold

Ask about any prescription or over-the-counter medication and we check it for interactions with Krill Oil Gold 500 mg by NutriGold — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Krill Oil Gold 500 mg by NutriGold

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • “Total Omega-3 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (240 mg) without saying how much of each component you get.
  • “Krill Oil” is listed as a grouped ingredient — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

This softgel contains five active ingredients: eicosapentaenoic acid and docosahexaenoic acid (two omega-3 fatty acids), total omega-3 fatty acids as a blend, phospholipids, and esterified astaxanthin — a carotenoid antioxidant derived from krill. The softgel shell itself is an inactive ingredient.

The omega-3s and phospholipids make up the core of krill oil's composition; astaxanthin is the colored compound that gives krill its reddish hue and is included here for its antioxidant properties.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Astaxanthin product and its label doesn't state a use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The effectiveness evidence for astaxanthin — the ingredient we hold data on — is not established. Our data show insufficient reliable evidence to rate it for age-related cognitive decline, macular degeneration, skin aging, Alzheimer disease, athletic performance, or carpal tunnel syndrome.

We don't hold effectiveness ratings for the omega-3 fatty acids and phospholipids in this product.

The evidence, ingredient by ingredient Krill Oil Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects reported orally are abdominal pain, diarrhea, and red or reddish-colored stools.

At typical doses (around 6 mg daily), a small number of trial participants experienced increased bowel movements and red stools; at much higher doses (40 mg daily), severe stomach pain occurred in two patients. Not enough safety data exist for astaxanthin in pregnancy or while breastfeeding, so the safety data advise against use during these times.

We don't hold pregnancy or breastfeeding safety information for the other ingredients in this product.

Side effects, ingredient by ingredient Krill Oil Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check with your own doctor or pharmacist if you're on any medications that your liver breaks down, particularly those metabolized by the CYP3A4 or CYP2B6 enzyme systems — astaxanthin may theoretically speed up how quickly your body clears them, potentially making them less effective, though this hasn't been confirmed in humans. The 672 affected medications are wide-ranging, so using the checker on this page with your actual prescriptions is important.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Krill Oil Gold is a straightforward omega-3 and astaxanthin supplement, but if you take medications metabolized by your liver — especially common blood pressure drugs, statins, immunosuppressants, or certain cancer medications — you'll want to check with your doctor or pharmacist before starting it. If you're pregnant or breastfeeding, talk with your healthcare provider about whether this product is right for you.

The long-term safety profile isn't fully mapped out yet.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Krill Oil Gold 500 mg, straight from the product label.

Brand NutriGold
Barcode (UPC) 859447002500
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Nov 19, 2021
DSLD ID 250956
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Krill Oil Gold 500 mg by NutriGold, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
859447002500
IngredientAmount% DV
Calories10 Calorie(s)--
Eicosapentaenoic Acid120 mg--
Docosahexaenoic Acid70 mg--
Cholesterol10 mg3%
Total Fat1 Gram(s)1%
Total Omega-3 Fatty Acids240 mg--
Phospholipids400 mg--
Esterified Astaxanthin200 mcg--
Other Omega-3 Fatty Acids50 mg--
Krill Oil1000 mg--

Other ingredients: Softgel shell

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Pure, completely traceable, sustainably-sourced Antarctic krill oil with naturally-occurring Astaxanthin processed on board for consistent freshness and quality.

High-absorption phospholipid omega-3s

Formulation

Verified free of corn, egg, gluten, milk, peanut, and soy allergens by an independent lab.

Tested and verified non-GMO by an independent lab

Certified-sustainable

Non GMO Verified No Harmful Additives

Gluten-Free Soy-Free

Precautions

Caution: Please consult a healthcare professional before taking this supplement if you are pregnant, breastfeeding, taking any medications, or have a known suspected allergy to shellfish.

Caution: Please consult a healthcare professional before taking this supplement if you are pregnant, breastfeeding, taking any medications, or have a known suspected allergy to shellfish.

Keep out of reach of children.

Contains shellfish (krill oil)

Storage

Store in original container away from moisture and direct sunlight.

Brand IP Statement(s)

Registered Trade Mark of Friend of the Sea

General Statements

To learn more about this product, scan QR code or visit nutrigold.com/item/250

FDA Statement of Identity

Omega 3 Supplement

Seals/Symbols

Friend Of The Sea

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, adults take two (2) softgels daily with breakfast, or as directed by a healthcare professional.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Krill Oil Gold 500 mg by NutriGold label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Krill Oil Gold 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Krill Oil Gold 500 mg by NutriGold

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Krill Oil

Interacts with
208 drugs
1000 mg per serving

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglyce...

Krill Oil monograph & interactions

Other (inactive) ingredients: Softgel shell. These complete the product’s ingredient list but are not active constituents.

Interaction report

Krill Oil Gold 500 mg by NutriGold Drug Interactions

Want to check YOUR meds against Krill Oil Gold 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
838Drugs
838 Moderate

Ingredients driving the most interactions

Krill Oil 208

Individual Drug Interactions

The ingredients in Krill Oil Gold 500 mg interact with 838 drugs. Click any drug to see the details.

1 of the 1 ingredient in Krill Oil Gold 500 mg interact with drugs. Each result below shows which ingredient is responsible. Krill Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Krill Oil Gold 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Krill Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Taking high doses of omega-3 fatty acids from fish oil can modestly decrease platelet aggregation. Since krill oil also contains these fatty acids, taking high doses of krill oil might also inhibit platelet aggregation. Theoretically, taking high doses of krill oil with antiplatelet or anticoagulant drugs might increase the risk of bleeding. However, the omega-3 content of krill oil is much lower than that of fish oil.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking krill oil with antidiabetes drugs might increase the risk of hypoglycemia.
Some research in animals and humans shows that krill oil might lower blood glucose levels. However, a small study shows that taking krill oil does not reduce blood glucose levels in patients with type 2 diabetes, most of whom were taking antidiabetes drugs.

Likelihood Possible Evidence B
Krill Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Krill Oil Gold 500 mg, from the product label.

NutriGold

Name
NutriGold Inc.
City
Orem
State
UT
ZipCode
84057
Phone Number
(800) 476-3542
Web Address
www.nutrigold.com
Pharmacist Counseling Corner

Krill Oil Gold 500 mg by NutriGold: Common Questions

Does Krill Oil Gold 500 mg by NutriGold interact with any medications?
Yes. Based on its ingredients, Krill Oil Gold 500 mg has a known interaction with 838 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Krill Oil Gold 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Krill Oil Gold if I'm pregnant?
No — there isn't enough safety data for astaxanthin in pregnancy, so the safety data advise against it. Talk with your doctor or pharmacist about your specific situation and what alternatives might work for you.
What's astaxanthin doing in this product?
Astaxanthin is a reddish antioxidant compound naturally present in krill; it's included for its antioxidant properties. It's the ingredient that gives krill oil its color.
Will this turn my stools red?
Red or reddish-colored stools are the most common side effect reported with astaxanthin. A small number of trial participants experienced this at typical doses, so it's a possible but generally minor side effect.
Does krill oil work for heart health or brain health?
We don't hold effectiveness data for the omega-3 ingredients in this product, so we can't tell you whether it does. The astaxanthin ingredient has insufficient evidence for conditions like cognitive decline or Alzheimer disease.
Are there any fillers in here?
The only inactive ingredient listed is the softgel shell itself — no extra fillers are listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Krill Oil Gold 500 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Krill Oil Gold 500 mg label
Go deeper

The Full Monographs Behind Krill Oil Gold 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Krill Oil

Interacts with 208 drugs

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglycerides and supporting heart health, but t...

Read the full Krill Oil monograph → Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Krill Oil Gold 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Krill Oil 13 references
  1. Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
  2. Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
  3. Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Nutr Res 2001;21:309-41. DOI
  4. Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Altern Med Rev 2004;9:420-8.
  5. Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-9.
  6. Harris WS, Miller M, Tighe AP, et al. Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives. Atherosclerosis 2008;197:12-24. PubMed
  7. Tandy S, Chung RW, Wat E, et al. Dietary krill oil supplementation reduces hepatic steatosis, glycemia, and hypercholesterolemia in high-fat-fed mice. J Agric Food Chem 10-14-2009;57:9339-45. PubMed
  8. Maki, K. C., Reeves, M. S., Farmer, M., Griinari, M., Berge, K., Vik, H., Hubacher, R., and Rains, T. M. Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr.R PubMed
  9. Albert BB, Derraik JG, Brennan CM, et al. Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men. Am J Clin Nutr 2015;102(1):49-57.
  10. Berge K, Musa-Veloso K, Harwood M, Hoem N, Burri L. Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride levels. Nutr Res 2014;34(2):126-33. PubMed
  11. Lobraico JM, DiLello LC, Butler AD, Cordisco ME, Petrini JR, Ahmadi R. Effects of krill oil on endothelial function and other cardiovascular risk factors in participants with type 2 diabetes, a randomized controlled trial. BMJ Open Diabetes Res Care. 2015 PubMed
  12. van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM. Krill oil supplementation's effect on school grades in typically developing adolescents. Prostaglandins Leukot Essent Fatty Acids 2023;191:102553. PubMed
  13. van der Wurff ISM, von Schacky C, Bergeland T, et al. Effect of 1 year krill oil supplementation on cognitive achievement of Dutch adolescents: A double-blind randomized controlled trial. Nutrients. 2019;11(6):1230. PubMed

See these in context on the Krill Oil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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