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Dietary supplement

Krill Oil Gold 500 mg Ingredients & Drug Interactions

by NutriGold

Krill Oil Gold 500 mg label
See full label image
Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Krill Oil Gold 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Krill Oil Gold 500 mg is a dietary supplement by NutriGold with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 838 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin, NKO Neptune Krill Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Krill Oil Gold 500 mg by NutriGold

Ask about any prescription or over-the-counter medication and we check it for interactions with Krill Oil Gold 500 mg by NutriGold — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Krill Oil Gold 500 mg by NutriGold

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • “Total Omega-3 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (252 mg) without saying how much of each component you get.
  • “NKO Neptune Krill Oil” is listed as a grouped ingredient — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

Krill Oil Gold contains five active ingredients: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)—both omega-3 fatty acids found in krill—along with phospholipids and astaxanthin (a naturally occurring carotenoid in krill). The product also lists other omega-3 fatty acids as part of its total omega-3 content.

It's encapsulated in a vegetarian capsule.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Heart health, cholesterol and triglyceride support.
  • We looked for evidence on: Cardiovascular disease (CVD), Hyperlipidemia, Hypertriglyceridemia, Heart failure, Dyslipidemia, Coronary artery disease.
  • The closest evidence on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Heart failure (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Hyperlipidemia.

Our data doesn't include effectiveness ratings for krill oil itself or most of its component fatty acids. Astaxanthin, the one ingredient we have effectiveness ratings for, shows insufficient reliable evidence to rate its use for age-related cognitive decline, macular degeneration, aging skin, Alzheimer disease, athletic performance, or carpal tunnel syndrome.

If you're considering this product for a specific health goal, talk it over with your doctor or pharmacist about what the research actually shows for your situation.

The evidence, ingredient by ingredient Astaxanthin Krill Oil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most commonly reported side effects in trials are abdominal pain, diarrhea, and red-colored stools.

A small number of people taking higher doses have reported increased bowel movements or more significant stomach pain. Safety data during pregnancy and breastfeeding are insufficient, so the evidence advises against use in both cases — talk with your doctor or pharmacist for personalized guidance if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Astaxanthin Krill Oil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any medications processed by your liver through the CYP3A4 or CYP2B6 enzyme systems, check with your doctor or pharmacist before adding this product. Astaxanthin may theoretically speed up how your body clears these drugs, potentially lowering their effectiveness.

For the omega-3 ingredients we could not check, no interaction data are on file.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Krill Oil Gold is marketed for its omega-3 fatty acid and astaxanthin content, though we don't have strong evidence ratings for most of those components. The main concern is that astaxanthin may theoretically alter how your liver processes certain medications.

Before you start, check your exact prescription list with your doctor or pharmacist — particularly if you take drugs metabolized through CYP3A4 or CYP2B6 pathways.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Krill Oil Gold 500 mg, straight from the product label.

Brand NutriGold
Barcode (UPC) 859447002517
Net contents 120 Liquid Veggie Capsule(s)
Market status On market
Date entered into DSLD Jan 25, 2017
DSLD ID 70121
Product type Fat/fatty Acid
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Krill Oil Gold 500 mg by NutriGold, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
859447002517
IngredientAmount% DV
Calories10 Calorie(s)--
Calories from Fat10 Calorie(s)--
Eicosapentaenoic Acid126 mg--
Docosahexaenoic Acid73 mg--
Phospholipids415 mg--
Cholesterol10 mg4%
Total Fat1 Gram(s)2%
Total Omega-3 Fatty Acids252 mg--
Other Omega-3 Fatty Acids53 mg--
Astaxanthin837 mcg--
NKO Neptune Krill Oil1000 mg--

Other ingredients: Vegetarian Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Krill oil, unlike fish oil, contains omega-3 fatty acids that are absorbed and carried to the body’s cells in phospholipid form and are easily recognized, absorbed and utilized by the body.

The NutriGold difference -No fishy after-taste, smaller easy-to-swallow softgels -Complies with USP standards for purity, potency and structure

-Encapsulated in the USA exceeding cGMP standards -Purity and potency verified by third-party labs

-Verified free of seven common allergens -Premium quality without the premium price tag

New odor-less liquid vegetarian capsules

Supports heart, joint & cognitive health

Formulation

-Made without harmful additives, fillers, and binderes

Made without additives, fillers, and binders

Non GMO

Gluten-free - Soy-free

Free of corn, egg, gluten, milk, peanut, shellfish and soy allergens. Does not contain flow agents, fillers, binders, artificial ingredients, preservatives, stearates, laurates, sulfates, or dioxides.

Precautions

Caution: Please consult your healthcare provider before taking this supplement if you are pregnant, breastfeeding, have a seafood allergy, coagulopathy, and/or are taking OTC or prescription medications for a health condition.

Caution: Please consult your healthcare provider before taking this supplement if you are pregnant, breastfeeding, have a seafood allergy, coagulopathy, and/or are taking OTC or prescription medications for a health condition.

Keep out of the reach of children.

Do not refrigerate.

Contains shellfish (krill oil) derivatives.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

NKO is a trademark of Neptune Technologies and Bioressources Inc. Quebec, Canada. Protected by US Patent # 6,800,299B1.

IKOS 5-star certified

General

SKU #251 951130

Formula

NKO

Contains shellfish (krill oil) derivatives.

Seals/Symbols

Non GMO project verified nongmoproject.org

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, adults take two (2) capsules daily with breakfast, or as directed by a healthcare professional.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Krill Oil Gold 500 mg by NutriGold label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Krill Oil Gold 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Krill Oil Gold 500 mg by NutriGold

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Astaxanthin

Interacts with
671 drugs
837 mcg per serving

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

NKO Neptune Krill Oil

Interacts with
208 drugs
1000 mg per serving

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglyce...

NKO Neptune Krill Oil monograph & interactions
  • › Phospholipids
  • › Total Omega-3 Fatty Acids

Other (inactive) ingredients: Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Krill Oil Gold 500 mg by NutriGold Drug Interactions

Want to check YOUR meds against Krill Oil Gold 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
838Drugs
838 Moderate

Ingredients driving the most interactions

Astaxanthin 671
NKO Neptune Krill Oil 208

Individual Drug Interactions

The ingredients in Krill Oil Gold 500 mg interact with 838 drugs. Click any drug to see the details.

2 of the 2 ingredients in Krill Oil Gold 500 mg interact with drugs. Each result below shows which ingredient is responsible. Astaxanthin NKO Neptune Krill Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Krill Oil Gold 500 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Astaxanthin full monograph & interactions

NKO Neptune Krill Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Taking high doses of omega-3 fatty acids from fish oil can modestly decrease platelet aggregation. Since krill oil also contains these fatty acids, taking high doses of krill oil might also inhibit platelet aggregation. Theoretically, taking high doses of krill oil with antiplatelet or anticoagulant drugs might increase the risk of bleeding. However, the omega-3 content of krill oil is much lower than that of fish oil.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking krill oil with antidiabetes drugs might increase the risk of hypoglycemia.
Some research in animals and humans shows that krill oil might lower blood glucose levels. However, a small study shows that taking krill oil does not reduce blood glucose levels in patients with type 2 diabetes, most of whom were taking antidiabetes drugs.

Likelihood Possible Evidence B
NKO Neptune Krill Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Krill Oil Gold 500 mg, from the product label.

NutriGold

Name
NutriGold Inc.
City
Orem
State
UT
ZipCode
84057
Phone Number
800-476-3542
Web Address
www.nutrigold.com
Pharmacist Counseling Corner

Krill Oil Gold 500 mg by NutriGold: Common Questions

Does Krill Oil Gold 500 mg by NutriGold interact with any medications?
Yes. Based on its ingredients, Krill Oil Gold 500 mg has a known interaction with 838 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Krill Oil Gold 500 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is in this krill oil product?
It contains two main omega-3 fatty acids—eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)—plus phospholipids and astaxanthin, which is a pigment naturally present in krill. All of these are housed in a vegetarian capsule.
Can I take this if I'm pregnant or breastfeeding?
The safety data for astaxanthin (the ingredient we have the most information on) aren't strong enough to know it's safe during pregnancy or breastfeeding, so it's best to avoid it. Talk with your doctor or pharmacist about whether this product is right for you in these situations.
What side effects might I notice?
Astaxanthin is generally well tolerated. The most common side effects reported in studies are abdominal pain, diarrhea, and red-colored stools. A small number of people, especially at higher doses, have reported increased bowel movements or more severe stomach pain.
Is there good evidence this works?
We don't have strong effectiveness data for krill oil or most of its omega-3 components. For astaxanthin specifically, the evidence is insufficient to rate it for the conditions typically mentioned (like age-related cognitive decline or macular degeneration). Check with your doctor about what research supports its use for your particular goal.
Will this interfere with my medications?
The astaxanthin in this product may theoretically slow down how your liver processes certain medications—especially those handled by CYP3A4 or CYP2B6 enzyme systems. Run your prescription list through the interaction checker on this page, or ask your pharmacist, before you start.
Are there any fillers or additives besides the active ingredients?
The product is encapsulated in a vegetarian capsule. No other inactive ingredients are listed on the label.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Krill Oil Gold 500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Krill Oil Gold 500 mg label
Go deeper

The Full Monographs Behind Krill Oil Gold 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph → Herb & supplement monograph

Krill Oil

Interacts with 208 drugs

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglycerides and supporting heart health, but t...

Read the full Krill Oil monograph →
Sources

Sources & How We Checked

Krill Oil Gold 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Krill Oil 13 references
  1. Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
  2. Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
  3. Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Nutr Res 2001;21:309-41. DOI
  4. Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Altern Med Rev 2004;9:420-8.
  5. Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-9.
  6. Harris WS, Miller M, Tighe AP, et al. Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives. Atherosclerosis 2008;197:12-24. PubMed
  7. Tandy S, Chung RW, Wat E, et al. Dietary krill oil supplementation reduces hepatic steatosis, glycemia, and hypercholesterolemia in high-fat-fed mice. J Agric Food Chem 10-14-2009;57:9339-45. PubMed
  8. Maki, K. C., Reeves, M. S., Farmer, M., Griinari, M., Berge, K., Vik, H., Hubacher, R., and Rains, T. M. Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr.R PubMed
  9. Albert BB, Derraik JG, Brennan CM, et al. Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men. Am J Clin Nutr 2015;102(1):49-57.
  10. Berge K, Musa-Veloso K, Harwood M, Hoem N, Burri L. Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride levels. Nutr Res 2014;34(2):126-33. PubMed
  11. Lobraico JM, DiLello LC, Butler AD, Cordisco ME, Petrini JR, Ahmadi R. Effects of krill oil on endothelial function and other cardiovascular risk factors in participants with type 2 diabetes, a randomized controlled trial. BMJ Open Diabetes Res Care. 2015 PubMed
  12. van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM. Krill oil supplementation's effect on school grades in typically developing adolescents. Prostaglandins Leukot Essent Fatty Acids 2023;191:102553. PubMed
  13. van der Wurff ISM, von Schacky C, Bergeland T, et al. Effect of 1 year krill oil supplementation on cognitive achievement of Dutch adolescents: A double-blind randomized controlled trial. Nutrients. 2019;11(6):1230. PubMed

See these in context on the Krill Oil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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