Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

L-Carnosine Ingredients & Drug Interactions

by Paradise

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

L-Carnosine is a dietary supplement by Paradise with 1 active ingredient. Its ingredients are commonly taken for anti-aging and general wellness, exercise performance and muscle support, brain and cognitive health.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Carnosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of L-Carnosine by Paradise

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-carnosine, a naturally occurring compound made of two amino acids. The capsule itself is made of plant cellulose.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Carnosine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: antioxidant support and cellular health.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Cataracts, Cognitive impairment, Diabetes, Diabetic nephropathy — and 4 related terms.
  • The closest evidence on file: Carnosine is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Carnosine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Cataracts, Cognitive impairment, Heart failure, and more.

The data we hold shows carnosine is possibly ineffective for autism spectrum disorder. For other uses listed here — including age-related cognitive decline, Alzheimer disease, athletic performance, cataracts, and general cognitive impairment — the evidence isn't established enough to rate it either way.

The evidence, ingredient by ingredient Carnosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Carnosine is generally well tolerated in short-term studies, but long-term safety information is limited, so we don't know how it holds up with extended use. Some people have reported decreased appetite, dry mouth, minor weight changes, foot and joint pain, or pneumonia when taking it.

Because there isn't enough safety information, you should avoid carnosine during pregnancy and while breastfeeding.

Side effects, ingredient by ingredient Carnosine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Carnosine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antidiabetes drugs (insulin, sulfonylureas, metformin, and others) are Moderate-severity concerns with carnosine because of an increased risk of low blood sugar. Check your exact medications before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

L-Carnosine may appeal to you if you're exploring options for cognitive or age-related concerns, though the evidence is thin. If you take any diabetes medication, check with us first — the interaction with blood sugar control is real.

Talk to your pharmacist about whether this fits your situation and how long you're planning to use it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Carnosine, straight from the product label.

Brand Paradise
Barcode (UPC) 601944777579
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336867
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Carnosine by Paradise, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
2 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
601944777579
IngredientAmount% DV
L-Carnosine500 mg--

Other ingredients: Plant Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Quality, purity, potency We are dedicated to sourcing premium ultra pure ingredients that meet the highest standards of excellence.

L-Carnosine has heavy metal, free radical and active sugar molecule scavenging activity.

Vegan

Non-GMO Gluten free

Anti-aging antioxidant

Contains no common allergens. Made without fillers.

Manufactured in the USA. GMP Quality Assured & FDA Registered.

General Statements

Paradise products have won over a decade of Best of Supplements Awards.

Formula

L-Carnosine is a proton buffering neuropeptide consisting of alanine and histidine (beta-alanyl-L-histidine). It is normally found in the brain, innervated tissues, the lens of the eye and skeletal muscle tissue. L-Carnosine has heavy metal, free radical and active sugar molecule scavenging activity.

Storage

Warning: Keep in a cool dry place, out of the reach of children.

Precautions

Warning: Keep in a cool dry place, out of the reach of children.

If pregnant, nursing, or using any prescription medication consult your health care professional before using this product.

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Paradise Enhancing Nature's Miracles Since 1994 Paradise EST. 1994

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1-2 vegetarian capsules daily or as directed by a qualified health care professional.

See for yourself

L-Carnosine by Paradise label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Carnosine by Paradise

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

L-Carnosine

Interacts with
86 drugs
500 mg per serving

Carnosine is a naturally occurring dipeptide (made of beta-alanine and histidine) that acts as an antioxidant and buffer in muscle and brain. It is so...

L-Carnosine monograph & interactions

Other (inactive) ingredients: Plant Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Carnosine by Paradise Drug Interactions

Want to check YOUR meds against L-Carnosine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Carnosine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Carnosine1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking carnosine with antidiabetes drugs might increase the risk of hypoglycemia.
Some, but not all, preliminary clinical research shows that carnosine might reduce fasting blood glucose levels.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for L-Carnosine, from the product label.

Paradise

See all Paradise products
Name
Paradise Herbs & Essentials, Inc.
Street Address
19051 Goldenwest St. #106-304
City
Huntington Beach
State
CA
ZipCode
92648
Web Address
www.paradiseherbs.com
Pharmacist Counseling Corner

L-Carnosine by Paradise: Common Questions

Does L-Carnosine by Paradise interact with any medications?
Yes. Based on its ingredients, L-Carnosine has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Carnosine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
No. There isn't enough safety information for either pregnancy or breastfeeding, so the data advises against using carnosine during both. Talk with your doctor or pharmacist for personalized advice.
What side effects might I notice?
Some people have reported decreased appetite, dry mouth, small weight changes, foot or joint pain, or pneumonia. They aren't common, but they have been reported.
Does carnosine really work for memory or cognitive decline?
We don't have enough reliable evidence to say whether it works for age-related cognitive decline, Alzheimer disease, or general cognitive impairment. For autism, it appears to be ineffective.
Is it safe to take long-term?
We have good safety data for short-term use, but long-term safety information is limited. If you're thinking about taking it for months or longer, check with your pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Carnosine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Carnosine label
Sources

Sources & How We Checked

L-Carnosine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Carnosine 5 references
  1. Chengappa KN, Turkin SR, DeSanti S, et al. A preliminary, randomized, double-blind, placebo-controlled trial of L-carnosine to improve cognition in schizophrenia. Schizophr Res 2012;142(1-3):145-52. PubMed
  2. Karkabounas S, Papadopoulos N, Anastasiadou C, et al. Effects of a-lipoic Acid, carnosine, and thiamine supplementation in obese patients with type 2 diabetes mellitus: A randomized, double-blind study. J Med Food. 2018;21(12):1197-1203.
  3. Peng W, Mao P, Liu L, et al. Effect of carnosine supplementation on lipid profile, fasting blood glucose, HbA1C and insulin resistance: a systematic review and meta-analysis of long-term randomized controlled trials. Complement Ther Med 2020;48:102241. PubMed
  4. Siriwattanasit N, Satirapoj B, Supasyndh O. Effect of oral carnosine supplementation on urinary TGF-ß in diabetic nephropathy: a randomized controlled trial. BMC Nephrol 2021;22(1):236. PubMed
  5. Sureshkumar K, Durairaj M, Srinivasan K, et al. Effect of L-Carnosine in Patients with Age-Related Diseases: A Systematic Review and Meta-Analysis. Front Biosci (Landmark Ed) 2023;28(1):18. PubMed

See these in context on the Carnosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring