Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

L-Tyrosine (500 mg) Ingredients & Drug Interactions

by BulkSupplements.com

L-Tyrosine (500 mg) label
See full label image
Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking L-Tyrosine (500 mg) against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

L-Tyrosine (500 mg) is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for mental focus and alertness, coping with stress, fatigue and sleep loss.Based on those ingredients, 21 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Tyrosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against L-Tyrosine (500 mg) by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with L-Tyrosine (500 mg) by BulkSupplements.com — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of L-Tyrosine (500 mg) by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-tyrosine, an amino acid your body uses to make neurotransmitters and thyroid hormones. Each capsule delivers 500 mg.

There are no inactive ingredients listed.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Tyrosine's overall clinical evidence instead.

Strong

Strong clinical evidence supports Tyrosine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Phenylketonuria (PKU) — rated "Effective" (Natural Medicines).
  • On file: Cognitive function — rated "Possibly Effective" (Natural Medicines).
  • On file: Memory — rated "Possibly Effective" (Natural Medicines).

L-Tyrosine is effective for phenylketonuria (PKU), a rare genetic condition where the body can't process another amino acid properly. It's possibly effective for cognitive function and memory—some evidence suggests it may help with focus and thinking, though the data isn't conclusive.

It's possibly ineffective for athletic performance, and the evidence is too limited to rate it for alcohol use disorder or dementia.

The evidence, ingredient by ingredient Tyrosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Tyrosine is generally well tolerated in healthy adults, though the safety data aren't extensive and you should talk to your doctor before taking it regularly. The most common side effects—reported in trial participants—are fatigue, headache, heartburn, and nausea, especially at higher doses.

Pregnancy and breastfeeding data are insufficient; there isn't enough information to know whether it's safe at supplemental doses during pregnancy or lactation, so talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Tyrosine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tyrosine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: Parkinson's medications.
  • For scale: 21 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take levodopa (Parkinson's medication) or thyroid hormone medications (like levothyroxine). Both are Moderate-severity interactions that need spacing or monitoring.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

L-Tyrosine may help with focus and memory, and it's the established treatment for PKU. If you take levodopa for Parkinson's or thyroid hormones, check with your doctor or pharmacist first—the interactions are manageable but need attention.

Otherwise, it's generally well tolerated, though headache, fatigue, and nausea can occur. Run your medications through the tool below before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Tyrosine (500 mg), straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X000PWEZOL
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Oct 22, 2021
DSLD ID 254839
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Tyrosine (500 mg) by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
X000PWEZOL
IngredientAmount% DV
L-Tyrosine500 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Clean & pure bulk supplements

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Formulation

Free of: Added sugar, soy, dairy, yeast, additives

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 capsule one to three times daily, or as directed by a physician.

Storage

Store in a dry, cool place

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

L-Tyrosine (500 mg) by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

L-Tyrosine (500 mg) label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in L-Tyrosine (500 mg) by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

L-Tyrosine

Interacts with
21 drugs
500 mg per serving

L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performan...

L-Tyrosine monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Tyrosine (500 mg) by BulkSupplements.com Drug Interactions

Want to check YOUR meds against L-Tyrosine (500 mg)?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
21Drugs
21 Moderate

Ingredients driving the most interactions

L-Tyrosine 21

Individual Drug Interactions

The ingredients in L-Tyrosine (500 mg) interact with 21 drugs. Click any drug to see the details.

1 of the 1 ingredient in L-Tyrosine (500 mg) interact with drugs. Each result below shows which ingredient is responsible. L-Tyrosine

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Tyrosine (500 mg) with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Tyrosine2 drug types · 21 drugs

Levodopa

Theoretically, tyrosine might decrease the effectiveness of levodopa.
Tyrosine and levodopa compete for absorption in the proximal duodenum by the large neutral amino acid (LNAA) transport system. Advise patients to separate doses of tyrosine and levodopa by at least 2 hours.

Likelihood Probable Evidence D
Thyroid Hormone

Theoretically, tyrosine might have additive effects with thyroid hormone medications.
Tyrosine is a precursor to thyroxine and might increase levels of thyroid hormones.

Likelihood Probable Evidence D
L-Tyrosine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for L-Tyrosine (500 mg), from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

L-Tyrosine (500 mg) by BulkSupplements.com: Common Questions

Does L-Tyrosine (500 mg) by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, L-Tyrosine (500 mg) has a known interaction with 21 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Tyrosine (500 mg) contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will L-Tyrosine help me focus or improve my memory?
The evidence suggests it's possibly effective for both cognitive function and memory, but it's not conclusive. Some people may notice a benefit, others may not—the research isn't strong enough to guarantee results for everyone.
What are the common side effects?
Fatigue, headache, heartburn, and nausea are the most common, especially at higher doses. These are usually mild and manageable, and may ease if you lower your dose.
Is L-Tyrosine safe to take every day?
It's generally well tolerated in healthy adults, but safety data aren't extensive. Talk to your doctor before starting regular use to make sure it's right for you.
Can I take L-Tyrosine while pregnant or breastfeeding?
There isn't enough data to know whether it's safe at supplemental doses during pregnancy or breastfeeding. Talk with your doctor or pharmacist—they can give you personalized advice based on your situation.
Can I take this with my Parkinson's medication?
L-Tyrosine and levodopa compete for absorption in your gut, so it can reduce how well the medication works. Space them at least 2 hours apart, and check with your doctor or pharmacist before combining them.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Tyrosine (500 mg) is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Tyrosine (500 mg) label
Go deeper

The Full Monographs Behind L-Tyrosine (500 mg)’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tyrosine

Interacts with 21 drugs

L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performance during short-term stress, sleep loss,...

Read the full Tyrosine monograph →
Sources

Sources & How We Checked

L-Tyrosine (500 mg)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tyrosine 4 references
  1. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
  2. DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
  3. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
  4. van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed

See these in context on the Tyrosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team