Lemon Balm Ingredients & Drug Interactions
by Hawaii Pharm
What is this page for?
First and foremost: checking Lemon Balm against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Lemon Balm is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, digestive upset.Based on those ingredients, 264 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lemon Balm Leaf Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Lemon Balm by Hawaii Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Lemon Balm by Hawaii Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Lemon Balm by Hawaii Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Lemon Balm Leaf Extract, a concentrated form of the lemon balm plant. It comes as a liquid in a base of alcohol, water, and glycerin.
Does it work?
Moderate evidence
Lemon balm is possibly effective for herpes labialis (cold sores) and for stress and depression, according to the evidence we have on file. That means some clinical studies suggest benefit, but the data isn't yet strong enough to call it proven.
If you're thinking about it for one of these uses, talk with your doctor about whether it makes sense for you.
How safe is it?
Well-documented data
Lemon balm is generally well tolerated for short-term use in healthy adults, though long-term safety at high doses hasn't been well studied. During pregnancy, there isn't enough reliable safety data — talk with your doctor before using it.
While breastfeeding, safety information is limited, so check with your doctor first. When taken by mouth, lemon balm hasn't been reported to cause dizziness or sedation more often than placebo in clinical trials.
A rare case of heart rhythm changes was reported in someone using a multi-ingredient product containing lemon balm, but it's unclear whether lemon balm alone was responsible.
Meds to double-check
Moderate interaction found
Before you start, check with your doctor or pharmacist if you take any CNS depressants (sedatives, sleep aids, anxiety medications, or certain pain relievers) — lemon balm may add to their effects. Also check if you're on thyroid hormone replacement therapy, since lemon balm may interfere with how it works.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Lemon Balm by Hawaii Pharm is possibly helpful for cold sores, stress, and depression if you're looking for a plant-based option. If you take a CNS depressant or thyroid hormone replacement, you'll want to check with your doctor or pharmacist before starting, since it may interact with both.
It's well tolerated for short-term use, though long-term safety isn't firmly established.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Lemon Balm, straight from the product label.
| Brand | Hawaii Pharm |
|---|---|
| Barcode (UPC) | 840253632296 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2023 |
| DSLD ID | 301395 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Lemon Balm by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lemon Balm Leaf Extract, Dry | 983 mg | -- |
Other ingredients: Alcohol, Water, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Hawaii Pharm Herbal Extract Highest quality since 2008
Suggested/Recommended/Usage/Directions
Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.
Precautions
Warning: We recommend to seek expert medical advice before taking.
Do not use if you are allergic to any ingredients.
Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.
Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.
May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.
Keep out of the reach of children!
Storage
Store in a cool dry place.
Seals/Symbols
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Organic Alcohol Based USA Made in United States of America
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Scan this QR-code to get 15% discount on your next purchase. Limited time deal.
Formula
Melissa officinalis
Organic Alcohol Based
Formulation
Only natural ingredients Purity is laboratory tested and verified
All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives
Not tested on animals
Organic Alcohol Based
Made in USA, Hawaii
FDA Statement of Identity
Herbal Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Lemon Balm by Hawaii Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Lemon Balm by Hawaii Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Lemon Balm Leaf Extract, Dry
Interacts with264 drugs
Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold so...
Lemon Balm Leaf Extract, Dry monograph & interactionsOther (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.
Lemon Balm by Hawaii Pharm Drug Interactions
HelloPharmacist Interaction Report
Lemon Balm Leaf Extract by Hawaii Pharm has documented interactions with two medication types.
The most serious concern is with CNS depressants (drugs that slow your brain and nervous system, like sedatives, sleep aids, and some pain relievers) — lemon balm may add to their drowsy or sedating effects. It also may interfere with thyroid hormone replacement therapy by blocking how your thyroid medication works.
Read the full breakdown — every affected drug type, severity by severity
The thyroid hormone interaction is moderate in severity. If you take thyroid medication, you'll want to check with your doctor or pharmacist before starting this product, as your dose might need adjusting or the timing of when you take each one might matter.
Altogether, these interactions span 264 individual medications. Use the search tool on this page to check your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Lemon Balm?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Lemon Balm interact with 264 drugs. Click any drug to see the details.
1 of the 1 ingredient in Lemon Balm interact with drugs. Each result below shows which ingredient is responsible. Lemon Balm Leaf Extract, Dry
AmitriptylineElavil
How Amitriptyline interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Amitriptyline, Perphenazine interactionAmobarbitalAmytal
How Amobarbital interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Amobarbital, Secobarbital interactionAprobarbital, Butabarbital, PhenobarbitalTriple Barbital
How Aprobarbital, Butabarbital, Phenobarbital interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aprobarbital, Butabarbital, Phenobarbital interactionAripiprazoleAbilify, Abilify Maintena, Abilify Mycite
How Aripiprazole interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aripiprazole interactionAripiprazole LauroxilAristada, Aristada Initio Kit
How Aripiprazole Lauroxil interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aripiprazole Lauroxil interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Hydrocodone interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Aspirin, Pentazocine interactionAtropine, Hyoscyamine, PhenobarbitalHypnaldyne
How Atropine, Hyoscyamine, Phenobarbital interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Atropine, Hyoscyamine, Phenobarbital interactionAtropine, Hyoscyamine, Phenobarbital, ScopolamineBarbidonna No. 2, Belladonna Phenobarbital
How Atropine, Hyoscyamine, Phenobarbital, Scopolamine interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Atropine, Hyoscyamine, Phenobarbital, Scopolamine interactionAtropine, Hyoscyamine, Scopolamine, PhenobarbitalBarbeloid, Donnatal #2, Donphen
How Atropine, Hyoscyamine, Scopolamine, Phenobarbital interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Atropine, Hyoscyamine, Scopolamine, Phenobarbital interactionAtropine, PhenobarbitalAnthrocol
How Atropine, Phenobarbital interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Atropine, Phenobarbital interactionAtropine, MeperidineAtropine, Meperidine
How Atropine, Meperidine interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Atropine, Meperidine interactionAtropine, Morphine SulfateAtropine, Morphine Sulfate
How Atropine, Morphine Sulfate interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Atropine, Morphine Sulfate interactionBelladona Extract, PhenobarbitalChardonna-2
How Belladona Extract, Phenobarbital interacts with Lemon Balm — through 1 ingredient. Tap an ingredient for the detail:
Lemon Balm Leaf Extract, DryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Leaf Extract, Dry + Belladona Extract, Phenobarbital interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Lemon Balm with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Lemon Balm Leaf Extract, Dry
Cns Depressants
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Lemon balm seems to have CNS depressant activity in animals and in humans.
Thyroid Hormone
Theoretically, lemon balm might interfere with thyroid hormone replacement therapy.
In vitro, constituents of lemon balm extract bind to thyroid stimulating hormone (TSH), preventing TSH receptor-binding and leading to the inhibition of TSH-stimulated adenylate cyclase activity. In animals, lemon balm extract has been shown to decrease levels of circulating TSH and inhibit thyroid secretion.
Brand information
Manufacturer and brand details for Lemon Balm, from the product label.
Hawaii Pharm
See all Hawaii Pharm products- Name
- Hawaii Pharm LLC
- Street Address
- 510 Sumner St. Ste. 613
- City
- Honolulu
- State
- HI
- ZipCode
- 96817
- Phone Number
- 888-854-2924
- Web Address
- www.hawaiipharm.com
Lemon Balm by Hawaii Pharm: Common Questions
Does Lemon Balm by Hawaii Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm pregnant?
Is it safe to use while breastfeeding?
Does lemon balm actually work for cold sores?
Will this make me drowsy?
What's in this besides the lemon balm extract?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Lemon Balm is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Lemon Balm’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Lemon Balm's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lemon Balm 12 references
- Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Phytomedicine 1994;1:25-31.
- Akhondzadeh S, Noroozian M, Mohammadi M, et al. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial. J Neurol Neurosurg Psychiatry 2003;74:863-6. PubMed
- Kennedy DO, Scholey AB, Tildesley NT, et al. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav 2002;72:953-64. PubMed
- Albrecht M, Berger W, Laux P, Schmidt U, et al. Psychopharmaka und Verkehrssicherheit. Der Einfluß von Euvegal® - Dragees forte auf die Fahrtüchtigkeit und Kombinationswirkungen mit Alkohol Z Allg Med 1995;71:1215-25.
- Herberg, KW. Nebenwirkungen pflanzlicher Beruhigungsmittel/ Leistung und Befinden nach Einnahme einer Baldrian-Hopfen-Kombination. Z.Allg Med 1996;72:234-240.
- Soulimani R, Fleurentin J, Mortier F, et al. Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse. Planta Med. 1991 Apr;57:105-9.
- Sourgens H, Winterhoff H, Gumbinger HG, et al. Antihormonal effects of plant extracts. TSH- and prolactin-suppressing properties of Lithospermum officinale and other plants. Planta Med. 1982 Jun;45:78-86. DOI
- Auf'mkolk M, Ingbar JC, Amir SM, et al. Inhibition by certain plant extracts of the binding and adenylate cyclase stimulatory effect of bovine thyrotropin in human thyroid membranes. Endocrinology. 1984 Aug;115:527-34. PubMed
- Santini F, Vitti P, Ceccarini G, et al. In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity. J Endocrinol Invest. 2003 Oct;26:950-5. PubMed
- Alijaniha F, et al. Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety. J Ethnopharmacol. 2015;164:378-384. doi: 10.1016/j.jep.2015.02.007. Epub 2015 Feb 11. PubMed
- Araj-Khodaei M, Noorbala AA, Yarani R, et al. A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression. BMC Complement Med Ther. 2020;20(1):207. PubMed
- Kucuk U, Pham M, Raza Raja MH, Saad Shaukat MH, Clark R. Transient complete atrioventricular block associated with herbal supplement use. S D Med 2023;76(7):311-313.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC