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Dietary supplement

Lime Powder 1000 mg Ingredients & Drug Interactions

by BulkSupplements.com

Powder Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Lime Powder 1000 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for source of vitamin c, digestive upset, skin care.Based on those ingredients, 886 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lime, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Lime Powder 1000 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: lime powder at 1,000 mg per serving. Lime is a citrus fruit used as a food flavoring and traditional remedy.

The powder also includes maltodextrin as an inactive ingredient to aid mixing and stability.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Lime product and its label doesn't state a use — see Lime's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that lime powder works for iron deficiency anemia, malaria, sickle cell disease, or smoking cessation. All the effectiveness ratings in our data show insufficient reliable evidence — meaning either no human trials exist, or the trials are too small or unclear to draw a conclusion.

That doesn't mean it doesn't work; it means we don't have the data to say either way.

The evidence, ingredient by ingredient Lime

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lime as a food is generally well tolerated. The safety notes point out that concentrated extracts or essential oils should be avoided unless your doctor clears them, since safety data on concentrated products is limited.

Orally, some people report diarrhea or tooth sensitivity when consuming lime juice, but these are rare. Topically, lime oil and juice can cause allergic skin reactions, and sun exposure after skin contact with lime can trigger phytophotodermatitis (a burn-like reaction).

Pregnancy and lactation data isn't on file for this ingredient — talk with your doctor or pharmacist for personalized advice if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Lime

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lime.
  • The most serious interaction on file is rated Moderate.
  • For scale: 887 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check lime powder with your pharmacist if you take drugs that make your skin sensitive to sunlight, or medications your liver processes through the CYP3A4 enzyme — this includes some blood pressure drugs, cholesterol medications, and immunosuppressants. Both interactions are rated Moderate.

No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Lime powder at food doses is generally well tolerated, but the interaction data matters if you take medications that depend on liver enzymes or make you sun-sensitive. If you're on any prescription medication, especially anything your doctor warned you about with grapefruit, check with us first.

A pharmacist can help you figure out whether this product and your medications play well together.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lime Powder 1000 mg, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X002KU02BB
Net contents 250 Gram(s); 8.8 Ounce(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 331165
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lime Powder 1000 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1000 mg
Maximum serving Sizes:
1000 mg
Servings per container
250
UPC/BARCODE
X002KU02BB
IngredientAmount% DV
Lime, Powder1000 mg--

Other ingredients: Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Lime powder 1000 mg per serving

Brand IP Statement(s)

BulkSupplements.com Clean & pure bulk supplements

Formulation

Color may vary

Free of: added sugar, soy, dairy, yeast, gluten

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1000 mg (about 1/3 tsp) once daily, or as directed by a physician.

Storage

Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place.

General Statements

Use an accurate milligram scale. New

See for yourself

Lime Powder 1000 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lime Powder 1000 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1000 mg Dosage formPowder Servings per container250 Amounts shown are per serving.

Lime, Powder

Interacts with
886 drugs
1000 mg per serving Form: Citrus aurantiifolia, Powder

Lime is a common citrus fruit and a good natural source of vitamin C and plant antioxidants. As a food it is generally safe and enjoyed by most people...

Lime, Powder monograph & interactions

Other (inactive) ingredients: Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lime Powder 1000 mg by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Lime Powder 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
886Drugs
886 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Lime Powder 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lime, Powder2 drug types · 886 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Animal research shows that phenolics in lime juice inhibit cytochrome P450 3A4. This has been demonstrated in rats treated with sildenafil, a CYP3A4 substrate, and high doses of lime juice.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, concomitant use of lime oil with photosensitizing drugs may increase the risk of phototoxicity.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Lime Powder 1000 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Lime Powder 1000 mg by BulkSupplements.com: Common Questions

Does Lime Powder 1000 mg by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Lime Powder 1000 mg has a known interaction with 886 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lime Powder 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood pressure or cholesterol medication?
Animal research suggests lime juice may affect how your liver breaks down certain blood pressure and cholesterol drugs. You'll need to check your specific medication with the tool on this page or ask your pharmacist — some drugs in these categories interact, others don't. Don't skip or change any medication on your own.
Will lime powder help with anemia?
The evidence we have isn't strong enough to say whether lime powder works for iron deficiency anemia. If you're dealing with anemia, talk with your doctor about proven treatments.
Is this safe to take every day?
Lime as a food is safe for most people in normal amounts. The safety data is less clear for concentrated powders taken daily, so it's worth discussing with your pharmacist, especially if you're on medications or have digestive sensitivities.
Can I take this if I'm pregnant or breastfeeding?
Safety data for this ingredient during pregnancy and lactation isn't on file. Talk with your doctor or pharmacist about whether it's right for you during these times — they can give you personalized advice.
What side effects does lime powder have?
Taken by mouth, diarrhea and tooth sensitivity are rare but possible. If you apply lime to your skin, it can rarely cause allergic reactions, and sun exposure afterward can trigger a burn-like skin reaction called phytophotodermatitis.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lime Powder 1000 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lime Powder 1000 mg label
Go deeper

The Full Monographs Behind Lime Powder 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Lime Powder 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lime 20 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Roesyanto-Mahadi ID, Geursen-Reitsma AM, van Joost T, et al. Sensitization to fragrance materials in Indonesian cosmetics. Contact Dermatitis 1990;22:212-7. PubMed
  3. Naganuma M, Hirose S, Nakayama Y, et al. A study of the phototoxicity of lemon oil. Arch Dermatol Res 1985;278:31-6. . PubMed
  4. Bailey DG, Dresser GK, Bend JR. Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice. Clin Pharmacol Ther 2003;73:529-37. PubMed
  5. Weber, I. C., Davis, C. P., and Greeson, D. M. Phytophotodermatitis: the other "lime" disease. J Emerg.Med 1999;17(2):235-237. PubMed
  6. Wagner, A. M., Wu, J. J., Hansen, R. C., Nigg, H. N., and Beiere, R. C. Bullous phytophotodermatitis associated with high natural concentrations of furanocoumarins in limes. Am.J Contact Dermat. 2002;13(1):10-14. PubMed
  7. Garcia, O. P., Diaz, M., Rosado, J. L., and Allen, L. H. Ascorbic acid from lime juice does not improve the iron status of iron-deficient women in rural Mexico. Am.J.Clin.Nutr. 2003;78(2):267-273. PubMed
  8. Coffman, K., Boyce, W. T., and Hansen, R. C. Phytophotodermatitis simulating child abuse. Am.J Dis.Child 1985;139(3):239-240. PubMed
  9. Adegoke SA, Oyelami OA, Olatunya OS, Adeyemi LA. Effects of lime juice on malaria parasite clearance. Phytother Res. 2011;25(10):1547-50. PubMed
  10. Adegoke SA, Shehu UA, Mohammed LO, Sanusi Y, Oyelami OA. Influence of lime juice on the severity of sickle cell anemia. J Altern Complement Med. 2013;19(6):588-92. PubMed
  11. Assarian Z, Nixon RL. Protein contact dermatitis caused by lime in a pastry chef. Contact Dermatitis. 2015;73(1):54-6. PubMed
  12. Bamise CT, Dinyain VE, Kolawole KA. Dental erosion due to lime consumption; review of literature and case report. East Afr J Public Health. 2009;6(2):141-3. PubMed
  13. Flugman SL. Mexican beer dermatitis: a unique variant of lime phytophotodermatitis attributable to contemporary beer-drinking practices. Arch Dermatol. 2010;146(10):1194-5. PubMed
  14. Galvañ-Pérez Del Pulgar JI, Linares-Barrios M, Galvañ-Pozo JI Jr. Acropigmentation of the dorsum of the hands from preparing mojitos: A lime-induced phytophotodermatosis. Actas Dermosifiliogr. 2016;107(3):253-5. DOI
  15. Hemmerling A, Potts M, Walsh J, Young-Holt B, Whaley K, Stefanski DA. Lime juice as a candidate microbicide? An open-label safety trial of 10% and 20% lime juice used vaginally. J Womens Health (Larchmt). 2007;16(7):1041-51. PubMed
  16. Mauck CK, Ballagh SA, Creinin MD, et al. Six-day randomized safety trial of intravaginal lime juice. J Acquir Immune Defic Syndr. 2008;49(3):243-50. PubMed
  17. Mioduszewski M, Beecker J. Phytophotodermatitis from making sangria: a phototoxic reaction to lime and lemon juice. CMAJ. 2015;187(10):756. PubMed
  18. Rungruanghiranya S, Ekpanyaskul C, Sakulisariyaporn C, Watcharanat P, Akkalakulawas K. Efficacy of fresh lime for smoking cessation. J Med Assoc Thai. 2012;95 Suppl 12:S76-82.
  19. Swerdlin A, Rainey D, Storrs FJ. Fragrance mix reactions and lime allergic contact dermatitis. Dermatitis. 2010;21(4):214-6. DOI
  20. Ademosun AO, Mohammed A, Oboh G, Ajeigbe OF. Influence of lemon (Citrus limon) and lime (Citrus aurantifolia) juices on the erectogenic properties of sildenafil in rats with L-NAME-induced erectile dysfunction. J Food Biochem 2022;46(2):e14074.

See these in context on the Lime monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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