No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Liposomal Glutathione 500 mg Ingredients & Drug Interactions

by Amandean

Liquid Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Liposomal Glutathione 500 mg is a dietary supplement by Amandean with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, skin lightening or brightening, detoxification support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Liposomal Glutathione 500 mg by Amandean

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Liposome Proprietary Blend” is a proprietary blend — the label gives one combined amount (500 mg) without saying how much of each component you get.

This product contains 3 active ingredients. Sunflower lecithin is a phospholipid derived from sunflower seeds; it's included here as part of the liposomal delivery system meant to help your body absorb the glutathione.

Glycerin is a sugar alcohol that acts as a preservative and sweetener. Glutathione is an antioxidant your cells make naturally—it's composed of three amino acids and plays a role in protecting cells from damage.

The liquid also contains water, natural flavors, stevia leaf extract, and potassium sorbate as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: antioxidant support and master antioxidant system.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for glutathione supplementation is mixed and incomplete. It's possibly effective for reducing nerve damage (neurotoxicity) from the chemotherapy drug cisplatin, but for other uses—including Alzheimer disease, nonalcoholic fatty liver disease, athletic performance, and cataracts—we don't have enough reliable evidence to rate it.

Sunflower lecithin's effectiveness is unclear for most conditions; the evidence is insufficient for brain health, anxiety, and bipolar disorder, and it's likely ineffective for Alzheimer disease. Glycerin in this product is included as a base ingredient, not for its therapeutic effect at these amounts.

The evidence, ingredient by ingredient Glutathione Lecithin Glycerol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sunflower lecithin is generally well tolerated, though it can cause abdominal pain, diarrhea, nausea, and fullness in some people. If you have an egg or soy allergy, check with your doctor first—lecithin can trigger allergic skin reactions in those with those allergies.

Glycerin at normal amounts is generally well tolerated but can cause bloating, diarrhea, nausea, vomiting, dizziness, and headache. Large oral doses are a concern for stomach upset and dehydration.

Glutathione's long-term safety is less well established, and the data advises against use during pregnancy and breastfeeding unless your doctor advises otherwise. If you're pregnant, breastfeeding, or planning to be, talk with your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Glutathione Lecithin Glycerol

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, if you take any medications—especially anything you've had to watch closely—confirm with your own doctor or pharmacist before adding this supplement.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Amandean Liposomal Glutathione 500 mg is a liquid antioxidant supplement with no documented interactions. It's generally well tolerated short-term, though some people may experience mild digestive side effects.

The evidence for what it can do is limited—glutathione may help with cisplatin-related nerve damage, but evidence for other uses is incomplete. If you're pregnant, breastfeeding, have asthma, or take regular medications, talk it over with your own doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Liposomal Glutathione 500 mg, straight from the product label.

Brand Amandean
Barcode (UPC) X001P6EJV5
Net contents 4 Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 276066
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Liposomal Glutathione 500 mg by Amandean, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 mL
Maximum serving Sizes:
4 mL
Servings per container
30
UPC/BARCODE
X001P6EJV5
IngredientAmount% DV
Sunflower Lecithin0 NP--
Glycerin0 NP--
Glutathione500 mg--
Liposome Proprietary Blend500 mg--

Other ingredients: Water, Purified, Natural Flavors, Stevia leaf extract, Potassium Sorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Amandean Liposomal Glutathione encapsulates 500 mg of reduced GSH into optimally sized liposomes that are easily absorbed into the bloodstream, for maximum bioavailability support. Glutathione is the most important molecule in your body's antioxidant system.

Reduced Liposomal Glutathione 500 mg Premium Liposomes: Contain non-GMO sunflower lecithin

Suggested/Recommended/Usage/Directions

Directions for use. Shake lightly before using. Take on an empty stomach or between meals. One serving is nearly a full teaspoon. Can take straight or mix with liquids. Use as directed by your healthcare professional.

Storage: Store in a cool dry place. Refrigerate for maximum potency and longevity. Use within 40 days of opening.

Precautions

Seek advice from your qualified healthcare provider prior to using this product.

Pregnant or lactating women and persons under 18 years of age should consult their healthcare provider before use.

Pregnant or lactating women and persons under 18 years of age should consult their healthcare provider before use.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Master antioxidant system Optimally-sized for absorption Manufactured in a cGMP facility

Vegan, soy-free, & sugar-free

Vegan, soy-free, & sugar-free Contain non-GMO sunflower lecithin

Amandean Liposomal Glutathione is made in the USA using the finest worldwide ingredients.

FDA Statement of Identity

Dietary Supplement

See for yourself

Liposomal Glutathione 500 mg by Amandean label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Liposomal Glutathione 500 mg by Amandean

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Glutathione

No known
interactions
500 mg per serving

Glutathione is a powerful antioxidant your body makes naturally, and many people take it as a supplement hoping for skin, detox, or anti-aging benefit...

Glutathione monograph & interactions

Liposome Proprietary Blend

500 mg per serving

Other (inactive) ingredients: Water, Purified, Natural Flavors, Stevia leaf extract, Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Liposomal Glutathione 500 mg by Amandean Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Liposomal Glutathione 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Liposomal Glutathione 500 mg, from the product label.

Amandean

See all Amandean products
Name
Amandean, LLC.
Street Address
774 Mays Blvd. #10-427
City
Incline Village
State
NV
ZipCode
89451
Web Address
www.amandean.com
Pharmacist Counseling Corner

Liposomal Glutathione 500 mg by Amandean: Common Questions

Does Liposomal Glutathione 500 mg by Amandean interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Liposomal Glutathione 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Liposomal Glutathione 500 mg contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is sunflower lecithin safe if I'm allergic to eggs or soy?
Lecithin can trigger allergic skin reactions in people with egg or soy allergies. If you have either allergy, check with your doctor or pharmacist before using this product.
Can I take this if I'm pregnant or breastfeeding?
Sunflower lecithin is likely safe during pregnancy and lactation. Glutathione is different—there isn't enough reliable safety information, so the data advises against it during pregnancy and breastfeeding unless your doctor advises otherwise. Talk with your doctor or pharmacist about whether this product is right for you.
What side effects might I notice?
The most common are digestive: abdominal pain, bloating, diarrhea, nausea, vomiting, dizziness, and headache. Most people tolerate it well, but if you notice any of these, you can dial back the dose or stop and talk with your pharmacist.
Does this actually work as an antioxidant?
Glutathione is an antioxidant your body makes naturally. Whether supplementing it boosts your antioxidant defense isn't well established in our data, except possibly for nerve damage from cisplatin chemotherapy. The evidence for other uses—like protecting against Alzheimer disease or supporting athletic performance—is too weak to say either way.
Why is glycerin in here?
Glycerin is added as a liquid base and preservative to keep the supplement stable and palatable. It's not there for a therapeutic effect at these amounts.
What's the liposomal delivery system supposed to do?
Liposomes are tiny fat-based spheres that can help your digestive system absorb certain compounds more easily. In this case, the sunflower lecithin makes up the liposomal shell around the glutathione to try to improve how much reaches your cells.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Liposomal Glutathione 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Liposomal Glutathione 500 mg label
Sources

Sources & How We Checked

Liposomal Glutathione 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lecithin 9 references
  1. Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
  4. Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
  5. Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1985;48:736-42. PubMed
  6. Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
  7. Drachman DA, Glosser G, Fleming P, et al. Memory decline in the aged: treatment with lecithin and physostigmine. Neurology 1982;32:944-50. PubMed
  8. Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
  9. Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:

See these in context on the Lecithin monograph →

Glycerol 8 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Wagner DR. Hyperhydrating with glycerol: implications for athletic performance. J Am Diet Assoc 1999;99:207-12. PubMed
  3. Yu YL, Kumana CR, Lauder IJ, et al. Treatment of acute cortical infarct with intravenous glycerol. A double-blind, placebo-controlled randomized trial. Stroke 1993;24:1119-24. PubMed
  4. Frei A, Cottier C, Wunderlich P, Ludin E. Glycerol and dextran combined in the therapy of acute stroke. A placebo-controlled, double-blind trial with a planned interim analysis. Stroke 1987;18:373-9. PubMed
  5. Balaskas E, Szepietowski JC, Bessis D, Ioannides D, Ponticelli C, Ghienne C, Taberly A, Dupuy P. Randomized, double-blind study with glycerol and paraffin in uremic xerosis. Clin J Am Soc Nephrol. 2011 Apr;6(4):748-52. PubMed
  6. Blanchet-Bardon C, Tadini G, Machado Matos M, Delarue A. Association of glycerol and paraffin in the treatment of ichthyosis in children: an international, multicentric, randomized, controlled, double-blind study. J Eur Acad Dermatol Venereol. 2012 Aug;26 PubMed
  7. Kajita N, Kanamori K, Yamamoto S, Yoshida K. Generalized Urticaria Caused by a Glycerin Enema in an Infant. J Investig Allergol Clin Immunol 2022;32(4):318-319. PubMed
  8. Suzuki R, Fukuyama K, Miyazaki Y, Namiki T. Contact urticaria syndrome and protein contact dermatitis caused by glycerin enema. JAAD Case Reports. 2016;2:108-10. PubMed

See these in context on the Glycerol monograph →

Glutathione 1 reference
  1. Marrades RM, Roca J, Barbera JA, et al. Nebulized glutathione induces bronchoconstriction in patients with mild asthma. Am J Respir Crit Care Med 1997;156(2 Pt 1):425-30. PubMed

See these in context on the Glutathione monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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