Major interaction on record — check this product against your medications before combining. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Liquid D-3 & MK-7 Ingredients & Drug Interactions

by NOW

Liquid D-3 & MK-7 label
See full label image
Liquid Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Liquid D-3 & MK-7 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Liquid D-3 & MK-7 is a dietary supplement by NOW with 2 active ingredients. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Liquid D-3 & MK-7 by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with Liquid D-3 & MK-7 by NOW — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Liquid D-3 & MK-7 by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid contains two active ingredients: Vitamin D3 and Vitamin K2 (also called MK-7). The product is formulated with medium chain triglyceride oil, sunflower oil, safflower oil, vitamin E, peppermint oil, and rosemary extract as inactive ingredients.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Bone and cardiovascular support.
  • We looked for evidence on: Cardiovascular disease (CVD), Osteoporosis, Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD), Hemorrhagic disease, Hypoprothrombinemia — and 3 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Hemorrhagic disease (Natural Medicines).
  • Also on file: Vitamin K is rated "Effective" for Hypoprothrombinemia, Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.

Vitamin K2 has solid evidence for supporting normal blood clotting and preventing bleeding disorders. It's also rated possibly effective for bone health (osteoporosis).

We don't hold effectiveness data for Vitamin D3 in our monograph system, so we cannot speak to what this product is intended to do overall.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin K taken by mouth is generally well tolerated. The most common side effects are mild—nausea, stomach upset, and diarrhea—though not everyone experiences them.

The safety data advises that normal dietary amounts are fine, but you should check with your doctor before taking supplements, especially if you have any medical conditions or take medications. Vitamin K2 is rated likely safe in pregnancy and breastfeeding.

We don't have pregnancy or breastfeeding safety data on file for Vitamin D3.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or any blood thinner, this product is not safe to use without your doctor's approval—Vitamin K2 can reverse the drug's protective effect. Check your exact medications with the search tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is straightforward for people looking to support bone health and normal clotting with vitamin K. If you take warfarin or another blood thinner, you'll need to talk with your pharmacist or doctor first—this product could interfere with how your medication works.

Anyone on other medications should check them against the interaction tool before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Liquid D-3 & MK-7, straight from the product label.

Brand NOW
Barcode (UPC) 733739003799
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 314423
Product type Vitamin
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Halal, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Liquid D-3 & MK-7 by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.184 mL
Maximum serving Sizes:
0.184 mL
Servings per container
163
UPC/BARCODE
733739003799
IngredientAmount% DV
Vitamin D362.5 mcg313%
Vitamin K2100 mcg--

Other ingredients: Medium Chain Triglyceride Oil, Sunflower Oil, Safflower Oil, Vitamin E, Peppermint Oil, Rosemary Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Shake well. Take 5 drops daily. Take directly or add to your favorite beverage. Best when taken with a fat-containing meal.

Precautions

Caution: For adults only.

Not for use in infants or children.

Consult physician if pregnant/nursing, taking any anti-coagulants (such as warfarin, Coumadin, heparin) or other medication, or have a medical condition.

Keep out of reach of children.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Brand IP Statement(s)

MenaQ7 is a registered trademark of NattoPharma ASA, Norway. Patents granted and pending.

Seals/Symbols

GMP Quality Assured

Crescent K (Halal)

Triangle K (Kosher)

Formulation

Bone & cardiovascular support

Non-GMO

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients.

Made in the USA with globally sourced ingredients.

Formula

2,500 IU Vitamin D-3 & 100 mcg Vitamin K-2 per 5 drops MenaQ7

Crescent K (Halal)

Triangle K (Kosher)

FDA Statement of Identity

A Dietary Supplement

General Statements

Vitamins

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a cool, dry place after opening.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Liquid D-3 & MK-7 by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Liquid D-3 & MK-7 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Liquid D-3 & MK-7 by NOW

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.184 mL Dosage formLiquid Servings per container163 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin D3

62.5 mcg per serving Form: Cholecalciferol

Vitamin K2

Interacts with
2 drugs
100 mcg per serving Form: MenaQ7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Other (inactive) ingredients: Medium Chain Triglyceride Oil, Sunflower Oil, Safflower Oil, Vitamin E, Peppermint Oil, Rosemary Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Liquid D-3 & MK-7 by NOW Drug Interactions

Want to check YOUR meds against Liquid D-3 & MK-7?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Vitamin K2 2

Individual Drug Interactions

The ingredients in Liquid D-3 & MK-7 interact with 2 drugs. Click any drug to see the details.

1 of the 2 ingredients in Liquid D-3 & MK-7 interact with drugs. Each result below shows which ingredient is responsible. Vitamin K2

Each ingredient & the kinds of drugs it affects

For each ingredient in Liquid D-3 & MK-7 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
Vitamin K2 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Liquid D-3 & MK-7, from the product label.

NOW

See all NOW products
Name
NOW FOODS
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

Liquid D-3 & MK-7 by NOW: Common Questions

Does Liquid D-3 & MK-7 by NOW interact with any medications?
Yes. Based on its ingredients, Liquid D-3 & MK-7 has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Liquid D-3 & MK-7 contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
No, not without talking to your doctor first. Vitamin K2 in this product directly blocks warfarin's ability to prevent blood clots. Your doctor may need to adjust your warfarin dose or choose a different product for you.
What are the side effects of Vitamin K2?
Most people tolerate it well. The most common mild effects are nausea, stomach upset, and diarrhea. Serious side effects are very rare when taken by mouth.
Is this safe during pregnancy or breastfeeding?
Vitamin K2 is rated likely safe in pregnancy and breastfeeding. We don't have safety data on file for Vitamin D3 in those situations, so ask your doctor or pharmacist for personalized advice.
What is Vitamin K2 (MK-7) used for?
It helps your body make clotting proteins and supports normal blood coagulation. It's also studied for bone health. Your body needs it for several critical functions.
Why does the label list oils and other ingredients?
Those are inactive ingredients—they're there to deliver the active vitamins, add flavor (the peppermint oil), and preserve the product. They're not the active parts, but they're necessary for how the liquid works.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Liquid D-3 & MK-7 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Liquid D-3 & MK-7 label
Go deeper

The Full Monographs Behind Liquid D-3 & MK-7’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph →
Sources

Sources & How We Checked

Liquid D-3 & MK-7's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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