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Dietary supplement

Lutein 20 mg with Zeaxanthin Ingredients & Drug Interactions

by Country Life

Lutein 20 mg with Zeaxanthin label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lutein 20 mg with Zeaxanthin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lutein 20 mg with Zeaxanthin is a dietary supplement by Country Life with 2 active ingredients. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Zeaxanthin Isomers. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lutein 20 mg with Zeaxanthin by Country Life

Ask about any prescription or over-the-counter medication and we check it for interactions with Lutein 20 mg with Zeaxanthin by Country Life — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lutein 20 mg with Zeaxanthin by Country Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel holds two active ingredients: lutein and zeaxanthin isomers — both carotenoids, the yellow-orange pigments your eyes naturally contain. The product also includes several inactive ingredients: safflower oil, gelatin, sunflower oil, glycerin, beeswax, soy lecithin, purified water, and mixed tocopherols (a form of vitamin E).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: eye health and blue light protection.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD).

Lutein is possibly effective for age-related macular degeneration (AMD) and cataracts — two common eye conditions. Zeaxanthin is also possibly effective for AMD.

Both compounds are possibly ineffective for retinitis pigmentosa, retinopathy of prematurity, and bronchopulmonary dysplasia. For zeaxanthin and cognitive decline or Alzheimer disease, the evidence just isn't established enough to say one way or another.

The evidence, ingredient by ingredient Lutein Zeaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lutein at 20 mg daily — the dose in this product — has not caused adverse effects in trials and is generally well tolerated. Both ingredients are rated likely safe in pregnancy and lactation.

That said, supplement safety data for these compounds during pregnancy and breastfeeding is limited, so talk with your doctor or pharmacist if you're pregnant or nursing and want to use this product.

Side effects, ingredient by ingredient Lutein Zeaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (a Moderate interaction with zeaxanthin), run them through our medication checker before starting this supplement. No other medication interactions are documented for lutein.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a good choice if you're looking for lutein and zeaxanthin to support eye health, especially for AMD or cataracts. If you take antidiabetes medications, check with us first — the zeaxanthin may theoretically lower your blood sugar.

Pregnant or breastfeeding? Worth a quick conversation with your pharmacist or doctor about the dose.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lutein 20 mg with Zeaxanthin, straight from the product label.

Brand Country Life
Barcode (UPC) 015794056058
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 333203
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lutein 20 mg with Zeaxanthin by Country Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
UPC/BARCODE
015794056058
IngredientAmount% DV
Lutein20 mg--
Zeaxanthin Isomers4 mg--

Other ingredients: Safflower Oil, Gelatin, Sunflower Oil, Glycerin, yellow Beeswax, Soy Lecithin, Water, Purified, Mixed Tocopherols, Tocopherols, Natural, Bovine Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Lutein and zeaxanthin are the main dietary carotenoids found in the human retina. These ingredients have been clinically shown to support eye health.

Lutemax 2020 Lutein & Zeaxanthin

Lutemax 2020 is clinically shown to: Minimize eye strain from prolonged use of e-devices Support shielding from blue-light

Formulation

For those with prolonged exposure to electronic device screens, this will minimize eye strain and help shield from damaging blue-light.

Yes certified gluten-free by GFCO.org No yeast, wheat or corn No milk, salt or sugar No preservatives, artificial colors, flavors or sweeteners No magnesium stearate

Yes manufacturing supports wind power

Certified gluten-free

Our pledge of integrity

100% bovine gelatin, BSE-free.

Made in USA with globally sourced ingredients

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Yes recyclable packaging

Brand IP Statement(s)

Lutemax 2020 is a registered trademark of OmniActive Health Technologies Ltd.

Country Life established 1971

Seals/Symbols

Certified B Corporation Certified Gluten Free GFCO.org

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take one (1) softgel daily with food.

Precautions

As a reminder, discuss the supplements and medications that you take with your health care providers.

Contains soy. 100% bovine gelatin, BSE-free.

Caution: If you are pregnant, nursing, or taking medication, have a medical condition or planning a surgery, consult a doctor before using this product.

Stop using and consult a doctor if any adverse reactions occur. Do not accept if seal is broken.

Keep out of the reach of children.

Storage

Store between 59 degrees - 86 degrees F.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lutein 20 mg with Zeaxanthin by Country Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lutein 20 mg with Zeaxanthin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lutein 20 mg with Zeaxanthin by Country Life

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lutein

No known
interactions
20 mg per serving Form: Aztec Marigold Flower Extract

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Zeaxanthin Isomers

Interacts with
86 drugs
4 mg per serving Form: Aztec Marigold flower extract

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The stron...

Zeaxanthin Isomers monograph & interactions

Other (inactive) ingredients: Safflower Oil, Gelatin, Sunflower Oil, Glycerin, Yellow Beeswax, Soy Lecithin, Water, Purified, Mixed Tocopherols, Tocopherols, Natural, Bovine Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lutein 20 mg with Zeaxanthin by Country Life Drug Interactions

Want to check YOUR meds against Lutein 20 mg with Zeaxanthin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Zeaxanthin Isomers 86

Individual Drug Interactions

The ingredients in Lutein 20 mg with Zeaxanthin interact with 86 drugs. Click any drug to see the details.

1 of the 2 ingredients in Lutein 20 mg with Zeaxanthin interact with drugs. Each result below shows which ingredient is responsible. Zeaxanthin Isomers

Each ingredient & the kinds of drugs it affects

For each ingredient in Lutein 20 mg with Zeaxanthin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Zeaxanthin Isomers1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
In an animal diabetic model, zeaxanthin has hypoglycemic effects. However, population research has found that increasing intake of dietary zeaxanthin plus lutein does not decrease the risk of developing type 2 diabetes.

Likelihood Possible Evidence D
Zeaxanthin Isomers full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lutein 20 mg with Zeaxanthin, from the product label.

Country Life

See all Country Life products
Name
Country Life, LLC
Street Address
180 Vanderbilt Motor Parkway
City
Hauppauge
State
NY
ZipCode
11788
Web Address
CountryLifeVitamins.com
Pharmacist Counseling Corner

Lutein 20 mg with Zeaxanthin by Country Life: Common Questions

Does Lutein 20 mg with Zeaxanthin by Country Life interact with any medications?
Yes. Based on its ingredients, Lutein 20 mg with Zeaxanthin has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lutein 20 mg with Zeaxanthin contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly are lutein and zeaxanthin?
They're carotenoids — natural pigments your eyes already contain. They're found in leafy greens and colorful vegetables, and they're thought to protect the macula (the central part of your retina) from damage.
Can I take this if I'm pregnant or breastfeeding?
Both ingredients are rated likely safe during pregnancy and lactation. But supplement safety data is limited, so talk with your doctor or pharmacist before starting — they can give you personalized advice based on your situation.
Does this product have any fillers?
It contains inactive ingredients like safflower oil, gelatin, glycerin, and beeswax — these are the softgel capsule materials and suspending ingredients, not active compounds.
How well does lutein work for cataracts?
Lutein is rated possibly effective for cataracts based on the evidence we hold. That means the data suggests it may help, but we don't have definitive proof yet.
Will this help with my macular degeneration?
Both lutein and zeaxanthin are possibly effective for age-related macular degeneration (AMD). If you have AMD or are at risk, this could be worth trying — but talk with your eye doctor about whether it's right for you.
Are there any side effects?
At 20 mg daily, lutein hasn't caused adverse effects in trials. Zeaxanthin is generally well tolerated at typical supplement doses. The main caution is a theoretical interaction with antidiabetes medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lutein 20 mg with Zeaxanthin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lutein 20 mg with Zeaxanthin label
Go deeper

The Full Monographs Behind Lutein 20 mg with Zeaxanthin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph → Herb & supplement monograph

Zeaxanthin

Interacts with 86 drugs

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The strongest evidence relates to slowing progres...

Read the full Zeaxanthin monograph →
Sources

Sources & How We Checked

Lutein 20 mg with Zeaxanthin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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