Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Lysine Mood Support Ingredients & Drug Interactions

by Good State

Lysine Mood Support label
See full label image
Capsule Category: Amino Acid/protein
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lysine Mood Support against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Lysine Mood Support is a dietary supplement by Good State with 1 active ingredient. Its ingredients are commonly taken for cold sores (herpes labialis), genital herpes outbreaks, supporting protein and collagen formation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated minor. The ingredients most likely to interact are L-Lysine Hydrochloride. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Lysine Mood Support by Good State

Ask about any prescription or over-the-counter medication and we check it for interactions with Lysine Mood Support by Good State — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Lysine Mood Support by Good State

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: L-lysine hydrochloride, an amino acid form of lysine. The capsule itself includes cellulose as an inactive ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lysine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: mood support and immune and energy support.
  • We looked for evidence on: Stress, Schizophrenia, anxiety, depression.
  • The closest evidence on file: Lysine is rated "Insufficient Reliable Evidence To Rate" for Schizophrenia (Natural Medicines).
  • Also on file: Lysine is rated "Insufficient Reliable Evidence To Rate" for Stress.

Lysine is possibly effective for herpes labialis, commonly known as cold sores. The evidence for other uses — child growth, pressure ulcers, and diabetic foot ulcers — is insufficient, meaning we don't have enough reliable data to rate them either way.

The evidence, ingredient by ingredient Lysine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lysine is generally well tolerated at typical doses, though high amounts may cause stomach upset like abdominal pain, diarrhea, and indigestion. Long-term safety from supplementation hasn't been thoroughly studied.

There's one uncommon case report of kidney problems linked to oral lysine use. If you're pregnant, lysine from food is fine, but supplement safety during pregnancy hasn't been well studied — check with your doctor first.

Similarly, there isn't enough reliable information about lysine supplements while breastfeeding, so caution is advised. Talk with your pharmacist or doctor for personalized guidance.

Side effects, ingredient by ingredient Lysine

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lysine.
  • The most serious interaction on file is rated Minor.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take a 5-HT4 agonist (a medication for certain digestive conditions), check it against this product before you start. Lysine may theoretically reduce how well it works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Lysine makes sense if you're dealing with cold sores and want a possibly effective option. Keep an eye out for stomach upset, especially at higher doses.

If you're pregnant, breastfeeding, or taking a 5-HT4 agonist, talk with your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lysine Mood Support, straight from the product label.

Brand Good State
Barcode (UPC) 850023847447
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 310856
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lysine Mood Support by Good State, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
850023847447
IngredientAmount% DV
L-Lysine Hydrochloride500 mg--

Other ingredients: Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Good State's Lysine Mood Support's active ingredient is L-Lysine HCL, an amino acid essential to every diet. This nutrient is not synthesized in the body, yet is critical to help boost the immune system, support energy levels and help reduce stress. Good State's Ionic Minerals are known for their high bioavailability while other supplements can be extremely low.

Good State's Nano Ionic Supplements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Contains no sugars, soy, GMO, dairy, gluten, starch, artificial flavors, colors, animal by-products, and is hypoallergenic.

Suitable for vegans.

Good State is proud to follow Good Manufacturing Practices (GMP)

100% satisfaction guaranteed

High bioavailability Professional grade

Contains no sugars, soy, GMO, dairy, gluten, starch, artificial flavors, colors, animal by-products, and is hypoallergenic.

Seals/Symbols

Made in USA

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults: Take 1 capsule with 6-8 oz of water or juice. Children: Please consult a physician. Use more if needed or as recommended by your healthcare professional. Do not take on an empty stomach. Do not take without water or juice.

Precautions

Children: Please consult a physician. Caution: Keep out of reach of children.

Do not take on an empty stomach. Do not take without water or juice. Always speak with your physician before using any dietary supplement. Do not use if tamper evident seal is broken or missing.

Storage

For freshness after opening, store in a cool, dark place.

General Statements

Give your body what it needs! Health solutions

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lysine Mood Support by Good State label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lysine Mood Support label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lysine Mood Support by Good State

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

L-Lysine Hydrochloride

Interacts with
1 drug
500 mg per serving

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...

L-Lysine Hydrochloride monograph & interactions

Other (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lysine Mood Support by Good State Drug Interactions

Want to check YOUR meds against Lysine Mood Support?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Minor

Ingredients driving the most interactions

L-Lysine Hydrochloride 1

Individual Drug Interactions

The ingredients in Lysine Mood Support interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Lysine Mood Support interact with drugs. Each result below shows which ingredient is responsible. L-Lysine Hydrochloride

Each ingredient & the kinds of drugs it affects

For each ingredient in Lysine Mood Support with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Lysine Hydrochloride1 drug type · 1 drug

5-Ht4 Agonists

Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.

Likelihood Unlikely Evidence D
L-Lysine Hydrochloride full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lysine Mood Support, from the product label.

Good State

Name
GoodState Inc.
Street Address
575 Virginia Dr., Suite C
City
Fort Washington
State
PA
ZipCode
19034
Phone Number
1-866-227-6097
Web Address
www.GoodState.com
Pharmacist Counseling Corner

Lysine Mood Support by Good State: Common Questions

Does Lysine Mood Support by Good State interact with any medications?
Yes. Based on its ingredients, Lysine Mood Support has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lysine Mood Support contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lysine actually help with cold sores?
The evidence says lysine is possibly effective for cold sores. That means there's some support for it, but it's not a lock — results vary from person to person. It's worth trying if you're looking for a natural option.
What side effects should I watch for?
At typical doses, lysine is generally well tolerated. The most common side effects are stomach-related: abdominal pain, diarrhea, and indigestion. These tend to happen at higher amounts. There's also one rare case report of kidney problems, though that's uncommon.
Is it safe to take if I'm pregnant?
Lysine from food is fine during pregnancy, but supplement safety hasn't been well studied. Talk with your doctor before starting a lysine supplement so you can make the right choice for you.
Can I take this while breastfeeding?
There isn't enough reliable information on lysine supplements during breastfeeding. Caution is advised, so check with your pharmacist or doctor for personalized guidance.
Will this help with other things like wound healing?
The evidence for pressure ulcers and diabetic foot ulcers is insufficient — we don't have enough reliable data to say whether lysine helps. Same goes for child growth. If you're interested in lysine for one of those uses, talk with your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lysine Mood Support is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lysine Mood Support label
Go deeper

The Full Monographs Behind Lysine Mood Support’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lysine

Interacts with 1 drug

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to try to prevent or shorten cold sores, but...

Read the full Lysine monograph →
Sources

Sources & How We Checked

Lysine Mood Support's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lysine 7 references
  1. Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
  2. McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
  3. DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
  4. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
  5. Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
  6. Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
  7. Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.

See these in context on the Lysine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team