No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Maca Root 4:1 Extract Ingredients & Drug Interactions

by Hard Rhino

Powder Category: Botanical
No known interaction
The interaction bottom line No known interaction

Maca Root 4:1 Extract is a dietary supplement by Hard Rhino with 1 active ingredient. Its ingredients are commonly taken for low libido and sexual function, energy and stamina, menopause symptoms.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Maca Root 4:1 Extract by Hard Rhino

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: maca root extract in a 4:1 concentration, which means the extract is more potent than the raw herb. Maca has been used traditionally in Peruvian cuisine for centuries.

The product itself has no inactive fillers — it's the extract alone.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Maca product and its label doesn't state a use — see Maca's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish how well maca root works for its commonly claimed uses. For amenorrhea (absent periods), anemia of chronic disease, sexual dysfunction related to antidepressants, athletic performance, and osteoporosis, the research is rated as insufficient to make a reliable call.

That doesn't mean it doesn't work — it means the quality or amount of study isn't there yet to say one way or another.

The evidence, ingredient by ingredient Maca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Maca is generally well tolerated as a food, but long-term safety studies in supplement amounts haven't been done, so there's a gap in what we know. If you eat fresh, uncooked maca, stomach pain can happen.

The safety data is not enough to recommend this supplement during pregnancy or breastfeeding — talk with your doctor or pharmacist about whether it's right for you in those situations.

Side effects, ingredient by ingredient Maca

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredient we could check in this product. That said, run your medications through the checker on this page before you start, just to be sure.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Maca root extract is a single-ingredient supplement with no documented drug interactions. It's generally well tolerated when taken as a supplement, but the evidence for what it actually does is still thin.

If you're considering it for a specific reason — sexual function, energy, or menstrual health — have that conversation with your doctor or pharmacist first to see if it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maca Root 4:1 Extract, straight from the product label.

Brand Hard Rhino
Barcode (UPC) 818132859812
Net contents 125 Gram(s); 4.4 Oz(s)
Market status On market
Date entered into DSLD Apr 25, 2017
DSLD ID 72653
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maca Root 4:1 Extract by Hard Rhino, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gram(s)
Maximum serving Sizes:
1 Gram(s)
Servings per container
125
UPC/BARCODE
818132859812
IngredientAmount% DV
Maca root extract1000 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1000 mg (scant ~1/2 tsp) mixed with 8-16 ounces of water or suitable beverage. Taken 1-3 times daily, preferably with meals or as directed by your qualified health professional.

1 Carefully measure out suggested serving size using a microscale. 2 Add to preferred beverage. 3 Mix well. 4 Drink within 10-15 minutes. How to use

Storage: Store in a cool, dry place. Re-seal zipper immediately after use to preserve freshness.

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases.

Precautions

Warning: Keep out of the reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions and/or taking prescription drug(s) or OTC medication(s).

Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions and/or taking prescription drug(s) or OTC medication(s).

Always consult with a qualified health physician before taking any new dietary supplement.

Do not use or consume if pressure seal is broken.

Do not use or consume if seal is broken.

Formulation

Allergens: This product contains no soy, dairy, dairy byproducts, eggs, shellfish, wheat, gluten, tree nuts, or sesame seeds.

This is a non-GMO ingredient.

No added fillers

General Statements

Pure powder

Only pure ingredients

Seals/Symbols

Lab tested for purity and quality

Packaged in USA

FDA Statement of Identity

Dietary Supplement

See for yourself

Maca Root 4:1 Extract by Hard Rhino label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Maca Root 4:1 Extract by Hard Rhino

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Gram(s) Dosage formPowder Servings per container125 Amounts shown are per serving.

Maca root extract

No known
interactions
1000 mg per serving

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca root extract monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maca Root 4:1 Extract by Hard Rhino Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Maca Root 4:1 Extract. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Maca Root 4:1 Extract, from the product label.

Hard Rhino

See all Hard Rhino products
Name
Guardian Wholesale
Street Address
1607 West Whispering Wind Drive
City
Phoenix
State
AZ
ZipCode
85085
Phone Number
(866) 961-8378
Web Address
HardRhino.com
Pharmacist Counseling Corner

Maca Root 4:1 Extract by Hard Rhino: Common Questions

Does Maca Root 4:1 Extract by Hard Rhino interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Maca Root 4:1 Extract. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Maca Root 4:1 Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data isn't there to say it's okay during pregnancy or breastfeeding. Talk with your doctor or pharmacist before using it in either situation — they can give you personalized advice based on your health.
Does maca root actually work for sexual function or energy?
The research we have is rated insufficient to say reliably. There isn't enough high-quality evidence yet to know whether it delivers on those claims. Your doctor or pharmacist can discuss what might work better for your specific concern.
Will this cause stomach pain?
Stomach pain is documented with fresh, uncooked maca. Since this is an extract, that risk is lower — but if you do get stomach upset after taking it, stop and mention it to your pharmacist.
Is this just maca with nothing else added?
Yes — the product has no inactive fillers or other ingredients. It's maca root extract in a concentrated 4:1 form.
How long can I safely take this?
Long-term safety studies haven't been done on maca supplements at higher doses, so there's a real gap in what we know about long-term use. Discuss your timeline and dose with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maca Root 4:1 Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maca Root 4:1 Extract label
Go deeper

The Full Monographs Behind Maca Root 4:1 Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Maca Root 4:1 Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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