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Dietary supplement

Tribulong Tribulus + Longjack 800/400 mg Ingredients & Drug Interactions

by Hard Rhino

Tribulong Tribulus + Longjack 800/400 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tribulong Tribulus + Longjack 800/400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tribulong Tribulus + Longjack 800/400 mg is a dietary supplement by Hard Rhino with 2 active ingredients. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 501 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tribulus Terrestris, Longjack Tongkat Ali. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Tribulong Tribulus + Longjack 800/400 mg by Hard Rhino

Ask about any prescription or over-the-counter medication and we check it for interactions with Tribulong Tribulus + Longjack 800/400 mg by Hard Rhino — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Tribulong Tribulus + Longjack 800/400 mg by Hard Rhino

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains two active ingredients: Longjack Tongkat Ali (Eurycoma longifolia) at 400 mg per capsule and Tribulus Terrestris at 800 mg per capsule. The inactive ingredients are vegetarian cellulose (the capsule shell), rice flour, and silicon dioxide.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle energy recovery and male sexual function.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Muscle strength, Age-related testosterone deficiency, Erectile dysfunction (ED), Sexual desire — and 4 related terms.
  • The strongest evidence on file: Tribulus is rated "Possibly Effective" for Sexual dysfunction (Natural Medicines).
  • Also on file: Eurycoma Longifolia is rated "Possibly Effective" for Sexual desire.
  • Also on file: Tribulus is rated "Possibly Ineffective" for Athletic performance.

For Longjack, the evidence shows it's possibly effective for sexual desire. The data we hold rates athletic performance as possibly ineffective, and back pain, osteoporosis, and diabetes are insufficient to rate — we don't have enough reliable evidence on those uses.

For Tribulus, sexual dysfunction is rated possibly effective. Athletic performance is possibly ineffective, and benign prostatic hyperplasia (BPH, or prostate enlargement) is insufficient to rate.

The evidence, ingredient by ingredient Eurycoma Longifolia Tribulus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both ingredients are generally well tolerated short-term in studies, but long-term safety data are limited and product quality can vary. Longjack may increase testosterone levels, which if pushed beyond normal range could bring on acne, insulin resistance, liver problems, and other testosterone-related side effects.

Tribulus is generally well tolerated when taken by mouth, though it can cause stomach upset like abdominal pain, cramping, nausea, vomiting, diarrhea, or constipation — though in one study these complaints occurred at similar rates in the tribulus group and placebo group. Rare serious effects reported include liver and kidney injury, seizures, and persistent painful erection.

Avoid Longjack during pregnancy because there isn't enough safety data and it may affect hormones; the same goes for breastfeeding. Tribulus is possibly unsafe in pregnancy and should be avoided; avoid it while breastfeeding as well due to lack of reliable safety information.

Side effects, ingredient by ingredient Eurycoma Longifolia Tribulus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Tribulus, Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 501 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Tribulong, double-check with your doctor or pharmacist if you're on any blood pressure medications (antihypertensives) or blood sugar-lowering drugs (antidiabetes medications) — both Moderate severity risks. If you take propranolol (Inderal), lithium, or drugs metabolized by your liver, those need review too.

No interactions are documented for the inactive ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is for people interested in sexual function and athletic performance, though the evidence for athletic benefit is weak. If you take blood pressure medications, diabetes medications, lithium, propranolol, or drugs your liver breaks down, talk with your doctor or pharmacist before starting this supplement — it may affect how those medications work.

Pregnant and breastfeeding individuals should avoid both ingredients. Check your exact medications with your own healthcare provider before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tribulong Tribulus + Longjack 800/400 mg, straight from the product label.

Brand Hard Rhino
Barcode (UPC) 798711499502
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2017
DSLD ID 72953
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tribulong Tribulus + Longjack 800/400 mg by Hard Rhino, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
798711499502
IngredientAmount% DV
Longjack Tongkat Ali400 mg--
Tribulus Terrestris800 mg--

Other ingredients: Vegetarian Cellulose, Rice Flour, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one serving (2 capsules). Taken 1-2 times daily with meals, once in the morning and/or 30 minutes prior to workout for best results.

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases.

Precautions

Warning: Keep out of the reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions and/or taking prescription drug(s) or OTC medication(s).

Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions and/or taking prescription drug(s) or OTC medication(s).

Always consult with a qualified health physician before taking any new dietary supplement.

Do not use or consume if seal is broken.

General Statements

Promotes musclar energy & recovery Improved libido & well-being Natural male enhancement

FDA Statement of Identity

Dietary Supplement

Formulation

Allergens: This product contains no soy, dairy & byproducts, eggs, fish, shellfish, wheat, gluten, tree nuts, or sesame seeds.

This contains non-GMO ingredients

Storage

Storage: Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tribulong Tribulus + Longjack 800/400 mg by Hard Rhino label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tribulong Tribulus + Longjack 800/400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tribulong Tribulus + Longjack 800/400 mg by Hard Rhino

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Longjack Tongkat Ali

Interacts with
248 drugs
400 mg per serving

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

Longjack Tongkat Ali monograph & interactions

Tribulus Terrestris

Interacts with
259 drugs
800 mg per serving Form: Saponins

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims...

Tribulus Terrestris monograph & interactions

Other (inactive) ingredients: Vegetarian Cellulose, Rice Flour, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tribulong Tribulus + Longjack 800/400 mg by Hard Rhino Drug Interactions

Want to check YOUR meds against Tribulong Tribulus + Longjack 800/400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
501Drugs
259 Moderate 242 Minor

Ingredients driving the most interactions

Tribulus Terrestris 259
Longjack Tongkat Ali 248

Individual Drug Interactions

The ingredients in Tribulong Tribulus + Longjack 800/400 mg interact with 501 drugs. Click any drug to see the details.

2 of the 2 ingredients in Tribulong Tribulus + Longjack 800/400 mg interact with drugs. Each result below shows which ingredient is responsible. Tribulus Terrestris Longjack Tongkat Ali

Each ingredient & the kinds of drugs it affects

For each ingredient in Tribulong Tribulus + Longjack 800/400 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Tribulus Terrestris3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Tribulus Terrestris full monograph & interactions

Longjack Tongkat Ali5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
Longjack Tongkat Ali full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tribulong Tribulus + Longjack 800/400 mg, from the product label.

Hard Rhino

See all Hard Rhino products
Name
Guardian Wholesale
Street Address
1607 West Whispering Wind Drive
City
Phoenix
State
AZ
ZipCode
85085
Phone Number
(866) 961-8378
Web Address
www.HardRhino.com
Pharmacist Counseling Corner

Tribulong Tribulus + Longjack 800/400 mg by Hard Rhino: Common Questions

Does Tribulong Tribulus + Longjack 800/400 mg by Hard Rhino interact with any medications?
Yes. Based on its ingredients, Tribulong Tribulus + Longjack 800/400 mg has a known interaction with 501 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tribulong Tribulus + Longjack 800/400 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product actually work for sexual performance?
Tribulus is rated possibly effective for sexual dysfunction based on the evidence we hold. Longjack is rated possibly effective for sexual desire. Both show promise, but neither has rock-solid proof — talk it over with your doctor about whether it's right for your situation.
Can I take this if I'm pregnant or breastfeeding?
No. Longjack has no enough safety data and may affect hormones, so it's advised against in pregnancy and while breastfeeding. Tribulus is rated possibly unsafe in pregnancy and should be avoided, and there isn't reliable safety information for breastfeeding either. Talk with your doctor or pharmacist about safer options.
What stomach problems might I have?
Tribulus can cause abdominal pain, cramping, nausea, vomiting, diarrhea, or constipation. However, in one study these complaints happened about as often in people taking tribulus as in those taking placebo. Longjack's common side effects aren't detailed in our data.
Will this raise my testosterone?
Longjack may increase testosterone levels in some people. If your levels go above normal, you could develop acne, insulin resistance, liver problems, or other testosterone-related side effects. If you're concerned about testosterone changes, check with your doctor or pharmacist before starting.
Is this safe to take long-term?
Both ingredients are generally well tolerated short-term in studies, but long-term safety data are limited and product quality can vary. There's no strong evidence on how safe it is to use these over months or years, so chat with your doctor if you're thinking long-term use.
What are the rare serious side effects I should know about?
Tribulus has rare reports of liver and kidney injury, seizures, and a persistent painful erection with sexual dysfunction. There's also been one case report of someone drinking very large amounts of tribulus water who developed seizures, kidney injury, and hepatitis. Stop and seek medical help right away if you notice anything unusual.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tribulong Tribulus + Longjack 800/400 mg label
Go deeper

The Full Monographs Behind Tribulong Tribulus + Longjack 800/400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Eurycoma Longifolia

Interacts with 248 drugs

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....

Read the full Eurycoma Longifolia monograph → Herb & supplement monograph

Tribulus

Interacts with 259 drugs

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...

Read the full Tribulus monograph →
Sources

Sources & How We Checked

Tribulong Tribulus + Longjack 800/400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Tribulus 10 references
  1. Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
  2. Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
  3. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
  4. Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
  5. Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
  6. Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
  7. Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
  8. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
  9. Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
  10. Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.

See these in context on the Tribulus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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