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Dietary supplement

Marigold (Calendula) Powder Ingredients & Drug Interactions

by TerraVita Premium Collection

Marigold (Calendula) Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Marigold (Calendula) Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Marigold (Calendula) Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for minor wounds and skin healing, skin inflammation and irritation, diaper rash.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Marigold, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Marigold (Calendula) Powder by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Marigold (Calendula) Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Marigold (Calendula) Powder by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: marigold powder (calendula). Marigold is a traditional herb with a long history of use, typically applied to skin or taken by mouth for various purposes.

There are no other inactive ingredients listed in this formulation.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Calendula product and its label doesn't state a use — see Calendula's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on marigold's effectiveness for its traditional uses isn't established in the data we hold. The product has been studied for acne, bacterial vaginosis, burns, chronic obstructive pulmonary disease, liver disease, and radiation dermatitis, but the evidence on all these uses is rated insufficient—meaning we don't have reliable data to say whether it works.

If you're considering this for a specific condition, talk it over with your doctor or pharmacist about what the current research actually shows.

The evidence, ingredient by ingredient Calendula

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Marigold is generally well tolerated when applied to the skin, but it can cause allergic reactions in people who are sensitive to it. Oral allergic reactions are also possible.

Because marigold belongs to the Asteraceae family (which includes ragweed, chrysanthemums, and daisies), people allergic to any of those plants should be especially cautious. Patch testing with calendula before use is recommended to check for sensitivity.

In rare cases, topical use has caused burning, itching, redness, and scaling, though the exact role of marigold in those reactions wasn't always clear. The safety data for taking marigold by mouth is limited, so oral use during pregnancy is considered likely unsafe and should be avoided.

If you're pregnant or breastfeeding and interested in this product, talk with your doctor or pharmacist before using it.

Side effects, ingredient by ingredient Calendula

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Calendula.
  • The most serious interaction on file is rated Minor.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take CNS depressants—medications like sedatives, sleep aids, or anti-anxiety drugs that slow your nervous system—check with your doctor or pharmacist before taking this product. Although the risk appears low based on decades of use, a Minor interaction is documented.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Marigold powder may interest you if you're drawn to traditional herbal remedies, but the evidence on whether it actually works for common uses isn't solid yet. The main caution is allergic reactions—especially if you're sensitive to ragweed or other plants in the same family—and the need to avoid oral use in pregnancy.

Check your exact medications (especially any that make you drowsy) and any known plant allergies with your doctor or pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Marigold (Calendula) Powder, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435116125
Net contents 1 Ounce(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 282444
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Marigold (Calendula) Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s)
Maximum serving Sizes:
0.25 Teaspoon(s)
Servings per container
28
UPC/BARCODE
064435116125
IngredientAmount% DV
Marigold, Powder1000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2004 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Marigold (Calendula) Powder by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Marigold (Calendula) Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Marigold (Calendula) Powder by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container28 Amounts shown are per serving.

Marigold, Powder

Interacts with
248 drugs
1000 mg per serving Form: Zeaxanthin

Calendula is a flowering plant whose petals are used mainly in skin creams, oils, and ointments to soothe minor irritation and support wound healing....

Marigold, Powder monograph & interactions
Interaction report

Marigold (Calendula) Powder by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Marigold (Calendula) Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
248 Minor

Ingredients driving the most interactions

Marigold, Powder 248

Individual Drug Interactions

The ingredients in Marigold (Calendula) Powder interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in Marigold (Calendula) Powder interact with drugs. Each result below shows which ingredient is responsible. Marigold, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Marigold (Calendula) Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Marigold, Powder1 drug type · 248 drugs

Cns Depressants

Theoretically, calendula might have additive effects when used with CNS depressants, although this appears to be unlikely.
Although some animal research has suggested that a saponoside constituent in calendula may have sedative effects, calendula has been used for over 30 years without reports of sedation in humans.

Likelihood Unlikely Evidence D
Marigold, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Marigold (Calendula) Powder, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Marigold (Calendula) Powder by TerraVita Premium Collection: Common Questions

Does Marigold (Calendula) Powder by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Marigold (Calendula) Powder has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Marigold (Calendula) Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this if I'm allergic to ragweed?
You should be very cautious. Marigold belongs to the same plant family as ragweed, and people allergic to ragweed are at higher risk for an allergic reaction to calendula. Patch testing with calendula before use is recommended to check your sensitivity.
Is this safe to take by mouth during pregnancy?
No. The safety data for taking marigold by mouth during pregnancy is limited, and it's considered likely unsafe. If you're pregnant and interested in this product, talk with your doctor first.
What does this powder actually do?
Marigold has been used traditionally for various purposes—including acne, burns, and wound healing—but the evidence on whether it actually works for these uses isn't established yet. We don't have reliable data to say whether it's effective.
What side effects should I watch for?
Allergic reactions are the main concern, whether you take it by mouth or apply it to your skin. Topically, burning, itching, redness, and scaling have been reported rarely. If you have sensitive skin or a known plant allergy, be especially careful.
Does calendula powder interact with sleep medications?
There's a theoretical Minor interaction—marigold might add to the drowsy effect of CNS depressants like sleep aids. It's unlikely based on real-world use, but mention any sleep or anti-anxiety medications to your doctor or pharmacist before starting this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Marigold (Calendula) Powder label
Go deeper

The Full Monographs Behind Marigold (Calendula) Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Calendula

Interacts with 248 drugs

Calendula is a flowering plant whose petals are used mainly in skin creams, oils, and ointments to soothe minor irritation and support wound healing. Some early research is promising for ski...

Read the full Calendula monograph →
Sources

Sources & How We Checked

Marigold (Calendula) Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Calendula 9 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Reider N, Komericki P, Hausen BM, et al. The seamy side of natural medicines: contact sensitization to arnica (Arnica montana L.) and marigold (Calendula officinalis L.). Contact Dermatitis 2001;45:269-72..
  3. Gol'dman II. [Anaphylactic shock after gargling with an infusion of Calendula]. Klin Med (Mosk) 1974;52:142-3.
  4. Paulsen E. Contact sensitization from Compositae-containing herbal remedies and cosmetics. Contact Dermatitis 2002;47:189-98. PubMed
  5. Bojadjiev C. On the sedative and hypotensive effect of preparations from the plant Calendula officinalis. Nauch Trud Visshi Med Inst Sof 1964;43:15-20.
  6. Samochowiec L. Pharmacological study of saponosides from Aralia mandshurica Rupr. et Maxim and Calendula officinalis L. Herba Pol. 1983;29:151-155.
  7. Madisetti M, Kelechi TJ, Mueller M, Amella EJ, Prentice MA. Feasibility, acceptability, and tolerability of RGN107 in the palliative wound care management of chronic wound symptoms. J Wound Care. 2017;26(Sup1):S25-S34. PubMed
  8. Final Assessment report on Calendula officinalis L., flos. European Medicines Agency: Committee on Herbal Medicinal Products (HMPC). 2018. EMA/HMPC/603409/2017. Available at: https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-cal
  9. Puaratanaarunkon T, Washrawirul C, Chuenboonngarm N, Noppakun N, Asawanonda P, Kumtornrut C. Efficacy and safety of a facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glaba root extract in the treatment of maskne: A

See these in context on the Calendula monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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