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Dietary supplement

Marjoram Non-Alcohol Ingredients & Drug Interactions

by Hawaii Pharm

Marjoram Non-Alcohol label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Marjoram Non-Alcohol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Marjoram Non-Alcohol is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for digestive upset, sleep and relaxation, respiratory complaints (cough, congestion).Based on those ingredients, 338 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Marjoram extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Marjoram Non-Alcohol by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Marjoram Non-Alcohol by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Marjoram Non-Alcohol by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This liquid supplement contains one active ingredient: certified organic marjoram extract. The product also includes two inactive ingredients—vegetable palm glycerin and Hawaiian artesian water—which serve as the liquid base and preservative.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Marjoram product and its label doesn't state a use — see Marjoram's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for marjoram extract isn't established in the data we hold. Our monograph lists asthma, Parkinson disease, polycystic ovary syndrome (PCOS), and period pain (dysmenorrhea) as areas studied, but each carries a rating of insufficient reliable evidence.

That means the research so far doesn't show whether it works for these purposes—not that it doesn't work, just that we don't have enough solid data to say.

The evidence, ingredient by ingredient Marjoram

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Marjoram is generally well tolerated as a food seasoning. However, concentrated extracts like this one have limited human safety data.

The main concern is in pregnancy: safety is not established, so medicinal doses should be avoided. Food amounts are likely fine, but this supplement is a concentrated form, so talk with your doctor or pharmacist before using it if you're pregnant or breastfeeding.

Side effects are uncommon but documented. A small number of trial participants using marjoram essential oil alongside other oils developed allergic skin reactions, particularly children with pre-existing eczema.

One case report describes a woman whose skin inflammation (perioral dermatitis) flared after eating marjoram-seasoned food and cleared when she stopped—then returned when she tried marjoram again. If you notice any skin irritation, stop and check with us.

Side effects, ingredient by ingredient Marjoram

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Marjoram.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 338 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this marjoram extract, double-check any blood thinners or antiplatelet drugs you're on—aspirin, clopidogrel, warfarin, enoxaparin, and others risk increased bleeding. Also flag any anticholinergic medications (like benztropine or biperiden) or cholinergic drugs (like donepezil or bethanechol) with us, since marjoram may change how they work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This marjoram extract is worth considering if you're exploring herbal options for asthma, Parkinson symptoms, PCOS, or period pain—though the evidence isn't solid yet. Be cautious if you take blood thinners or any nerve-signaling medications.

Pregnant or breastfeeding? Talk with your pharmacist before using medicinal amounts.

Either way, check your exact medications before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Marjoram Non-Alcohol, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 0727973546747
Net contents 4 Fluid Ounce(s); 120 mL
Market status Off market
Date entered into DSLD Oct 23, 2020
DSLD ID 238221
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Marjoram Non-Alcohol by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
20 Drop(s)
Maximum serving Sizes:
30 Drop(s)
UPC/BARCODE
0727973546747
IngredientAmount% DV
certified organic Marjoram extract0 NP--

Other ingredients: Vegetable Palm Glycerin, crystal clear artesian Hawaiian Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Non-Alcohol Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no gluten, artificial colors, pesticides, preservatives, heavy metals. Non GMO.

Super concentrated liquid herbal extract Dry herb/menstruum ratio: 1:3

Contains no alcohol

Description: We produced this extract according to precise standards where each herbs are individually extracted according to their distinct characteristic. We use a cold maceration extraction method, so that the active constituents of the herbs are extracted and maintained.

Manufactured in an FDA registered facility. Ultra Sonic

Non GMO Gluten free

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops in juice, water, tea or as desired up to four times per day.

Precautions

Warnings: Keep out of the reach of children.

Not to be used during pregnancy. Consult a physician before using if nursing or taking any medications.

Do not use if you are allergic to any ingredients.

Do not use if seal is broken or missing.

Storage

Refrigerate after opening.

Formula

(Origanum majorana)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Marjoram Non-Alcohol by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Marjoram Non-Alcohol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Marjoram Non-Alcohol by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size20 Drop(s) Dosage formLiquid Amounts shown are per serving.

Certified organic Marjoram extract

Interacts with
338 drugs
0 NP per serving

Marjoram is a Mediterranean kitchen herb related to oregano that is widely used in food and traditional medicine for digestive, sleep, and respiratory...

Certified organic Marjoram extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Crystal clear artesian Hawaiian Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Marjoram Non-Alcohol by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Marjoram Non-Alcohol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
338Drugs
338 Moderate

Ingredients driving the most interactions

certified organic Marjoram extract 338

Individual Drug Interactions

The ingredients in Marjoram Non-Alcohol interact with 338 drugs. Click any drug to see the details.

1 of the 1 ingredient in Marjoram Non-Alcohol interact with drugs. Each result below shows which ingredient is responsible. certified organic Marjoram extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Marjoram Non-Alcohol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Marjoram extract3 drug types · 338 drugs

Anticholinergic Drugs

In vitro research suggests that marjoram extract can inhibit acetylcholinesterase activity. Theoretically, using marjoram in medicinal amounts along with anticholinergic drugs might decrease the effectiveness of marjoram or the anticholinergic agent.
Some anticholinergic drugs include atropine, benztropine (Cogentin), biperiden (Akineton), procyclidine (Kemadrin), and trihexyphenidyl (Artane).

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

In vitro research suggests that marjoram extract inhibits platelet aggregation and adhesion. Theoretically, marjoram might increase the risk of bleeding when used in medicinal amounts along with antiplatelet or anticoagulant drugs.
Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Cholinergic Drugs

In vitro research suggests that marjoram extract can inhibit acetylcholinesterase activity. Theoretically, using marjoram in medicinal amounts along with cholinergic drugs might have additive effects and increase the risk of cholinergic side effects.
Cholinergic drugs include bethanechol (Urecholine), donepezil (Aricept), echothiophate (Phospholine Iodide), edrophonium (Enlon, Reversol, Tensilon), neostigmine (Prostigmin), physostigmine (Antilirium), pyridostigmine (Mestinon, Regonol), succinylcholine (Anectine, Quelicin), and tacrine (Cognex).

Likelihood Possible Evidence D
certified organic Marjoram extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Marjoram Non-Alcohol, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Pharmacist Counseling Corner

Marjoram Non-Alcohol by Hawaii Pharm: Common Questions

Does Marjoram Non-Alcohol by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Marjoram Non-Alcohol has a known interaction with 338 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Marjoram Non-Alcohol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is marjoram safe to use if I'm pregnant?
Safety in pregnancy is not established for medicinal or concentrated amounts like this extract. Food-level marjoram is likely okay, but since this is a concentrated supplement, it's best to avoid it and talk with your doctor or pharmacist before using it if you're pregnant or planning to be.
Can marjoram cause skin problems?
Skin reactions are rare but have been reported. Some people—especially children with pre-existing eczema—developed allergic skin reactions from marjoram essential oil. One woman also developed inflamed skin around her mouth after eating marjoram-seasoned food. If you notice any rashes or skin irritation, stop taking it and let us know.
Does this marjoram extract actually work for asthma, PCOS, or period pain?
The evidence isn't established in the data we hold. Studies have looked at marjoram for these conditions, but there's not enough solid research yet to say whether it helps. You might try it, but don't count on it as a main treatment—talk with your doctor first.
Why is this a non-alcohol liquid instead of a capsule?
The product facts don't explain the choice of form, so I can't say for sure. But alcohol-free liquids are gentler on some people's stomachs and may work faster since they don't need to be digested as a solid.
What exactly is in the liquid besides the marjoram extract?
The inactive ingredients are vegetable palm glycerin and crystal clear artesian Hawaiian water. These are both used to create and preserve the liquid base—no fillers or artificial additives.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Marjoram Non-Alcohol is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Marjoram Non-Alcohol label
Go deeper

The Full Monographs Behind Marjoram Non-Alcohol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Marjoram

Interacts with 338 drugs

Marjoram is a Mediterranean kitchen herb related to oregano that is widely used in food and traditional medicine for digestive, sleep, and respiratory complaints. Most of its health claims r...

Read the full Marjoram monograph →
Sources

Sources & How We Checked

Marjoram Non-Alcohol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Marjoram 11 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Orhan, I., Kartal, M., Kan, Y., and Sener, B. Activity of essential oils and individual components against acetyl- and butyrylcholinesterase. Z.Naturforsch.C. 2008;63(7-8):547-553.
  3. Farkas, J. Perioral dermatitis from marjoram, bay leaf and cinnamon. Contact Dermatitis 1981;7(2):121. PubMed
  4. Anderson C, Lis-Balchin M, Kirk-Smith M. Evaluation of massage with essential oils on childhood atopic eczema. Phytother Res 2000;14(6):452-6. PubMed
  5. Ou, M. C., Hsu, T. F., Lai, A. C., Lin, Y. T., and Lin, C. C. Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial. J Obstet.Gynaecol.Res 2012;38(5):817-822. PubMed
  6. Chung, Y. K., Heo, H. J., Kim, E. K., Kim, H. K., Huh, T. L., Lim, Y., Kim, S. K., and Shin, D. H. Inhibitory effect of ursolic acid purified from Origanum majorana L on the acetylcholinesterase. Mol.Cells 4-30-2001;11(2):137-143. DOI
  7. Yazdanparast, R. and Shahriyary, L. Comparative effects of Artemisia dracunculus, Satureja hortensis and Origanum majorana on inhibition of blood platelet adhesion, aggregation and secretion. Vascul.Pharmacol 2008;48(1):32-37. PubMed
  8. Mohamed MS, Saad HH, and Abd El Khalek MG. Daily consumption of marjoram oil improve the health status of patients with asthma. Pakistan Journal of Nutrition. 2008;7(2):312-316. DOI
  9. Bina F, Rahimi R. Sweet marjoram: a review of ethnopharmacology, phytochemistry, and biological activities. J Evid Based Complementary Altern Med 2017;22(1):175-85.
  10. Haj-Husein I, Tukan S, Alkazaleh F. The effect of marjoram (Origanum majorana) tea on the hormonal profile of women with polycystic ovary syndrome: a randomized controlled pilot study. J Hum Nutr Diet 2016;29(1):105-11.
  11. Chahra C, Anis H, Bissene D, et al. The effect of Origanum majorana tea on motor and non-motor symptoms in patients with idiopathic Parkinson's disease: A randomized controlled pilot study. Parkinsonism Relat Disord. 2021 Oct;91:23-7. PubMed

See these in context on the Marjoram monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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