Primordial Pro Hypertrophic Stack Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Primordial Pro Hypertrophic Stack against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Primordial Pro Hypertrophic Stack is a dietary supplement by DNA Anabolics with 4 active ingredients. Its ingredients are commonly taken for lowering estrogen levels, post-cycle therapy after steroid or prohormone use, reducing gynecomastia ('gyno').Based on those ingredients, 4 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Androsta-3,5-Diene-7,17-Dione. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Primordial Pro Hypertrophic Stack by DNA Anabolics
Ask about any prescription or over-the-counter medication and we check it for interactions with Primordial Pro Hypertrophic Stack by DNA Anabolics — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Primordial Pro Hypertrophic Stack by DNA Anabolics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Primordial Pro Hypertrophic Stack contains 4 active ingredients — all of them synthetic compounds designed to alter hormone levels in the body. Three of them (4-chloro-17a-methyl-androst-4-en-17{Beta}-ol-3-one, 17a-methyl-1,4-androstadiene-3,17diol, and 13-ethyl-3-methoxy-gona-2,5(10)-diene-17-one) are not individually established in our data.
The fourth, Arimistane, is believed to inhibit aromatase, an enzyme involved in estrogen production. The product also contains gelatin and magnesium stearate as inactive ingredients.
Does it work?
Not established
The evidence backing Arimistane for any specific use — athletic performance, muscle strength, erectile dysfunction, sexual arousal, or obesity — is insufficient to rate. We simply don't have reliable data showing it works for these purposes.
The other three active ingredients in this product lack effectiveness ratings in our data as well.
How safe is it?
Some data gaps
Arimistane is flagged as a hormone-altering drug with very little safety data, and regulators warn against aromatase inhibitor supplements. It's rated Possibly Unsafe in pregnancy because lowering estrogen during pregnancy could be harmful — do not use if you're pregnant or trying to conceive.
There's also insufficient data to know whether it's safe while breastfeeding, so it should be avoided during lactation. No adverse effects are documented in trial data, but the lack of safety studies means risks may not be fully known.
Meds to double-check
Moderate interaction found
Before you take this product, double-check with your doctor or pharmacist if you're on aromatase inhibitors (a Moderate interaction concern). Because we cannot check three of the four active ingredients, also let your healthcare provider know the full ingredient list so they can flag any other risks you might face.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.
This is a hormone-altering supplement with very limited safety evidence and regulatory caution attached to it. If you take any cancer medications, hormone therapies, or drugs affecting estrogen or your liver, check with your doctor or pharmacist before you start — interactions are possible and the safety profile is unclear.
Pregnant or breastfeeding people should not use it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Primordial Pro Hypertrophic Stack, straight from the product label.
| Brand | DNA Anabolics |
|---|---|
| Barcode (UPC) | 036000291452 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 23, 2015 |
| DSLD ID | 41561 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Primordial Pro Hypertrophic Stack by DNA Anabolics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| 4-chloro-17a-methyl-androst-4-en-17{Beta}-ol-3-one | 17.5 mg | -- |
| 17a-methyl-1,4-androstadiene-3,17diol | 25 mg | -- |
| Androsta-3,5-Diene-7,17-Dione | 10 mg | -- |
| 13-ethyl-3-methoxy-gona-2,5(10)-diene-17-one | 30 mg | -- |
Other ingredients: Gelatin, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Must be 21 years of age to purchase this product.
Do not exceed 8 weeks of continuous use.
WARNING: Consult with a licensed physician before using this product. Do not take this product if you have prostate hypertophy, liver disease, kidney or heart disease. This product should not be taken by women.
In particular, those women who are pregnant, lactating or trying to become pregnant.
Do not take this product if you have been diagnosed with high cholesterol, prostate cancer, testicular cancer, breast cancer, or are under the age of 21.
Keep this product and all other supplements out of reach of children.
Suggested/Recommended/Usage/Directions
Directions: As a physique enhancing agent, take 1 capsule 2-3 times per day. Do not exceed 3 capsules in a 24 hour period. Always follow Primoridal with proper post cycle.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
DIETARY SUPPLEMENT
General Statements
Made in the USA
PHYSIQUE ENHANCING AGENT
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Primordial Pro Hypertrophic Stack by DNA Anabolics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Primordial Pro Hypertrophic Stack by DNA Anabolics
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
4-chloro-17a-methyl-androst-4-en-17{Beta}-ol-3-one
17a-methyl-1,4-androstadiene-3,17diol
Androsta-3,5-Diene-7,17-Dione
Interacts with4 drugs
Arimistane (sometimes sold as Estrovade) is a synthetic aromatase inhibitor marketed as a dietary supplement to lower estrogen and raise testosterone,...
Androsta-3,5-Diene-7,17-Dione monograph & interactions13-ethyl-3-methoxy-gona-2,5(10)-diene-17-one
Other (inactive) ingredients: Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Primordial Pro Hypertrophic Stack by DNA Anabolics Drug Interactions
HelloPharmacist Interaction Report
Primordial Pro Hypertrophic Stack by DNA Anabolics contains one ingredient with documented interactions: Arimistane.
It interacts with aromatase inhibitors (a class of drugs used mainly in hormone-sensitive cancers and sometimes in other conditions), and the interaction is rated Moderate in severity. Arimistane is believed to inhibit the aromatase enzyme, the same target as prescription aromatase inhibitors, which could increase the risk of side effects tied to low estrogen levels or liver toxicity.
Read the full breakdown — every affected drug type, severity by severity
We cannot check three of the four active ingredients in this product — 4-chloro-17a-methyl-androst-4-en-17{Beta}-ol-3-one, 17a-methyl-1,4-androstadiene-3,17diol, and 13-ethyl-3-methoxy-gona-2,5(10)-diene-17-one — because we hold no interaction data for them. That doesn't mean they're risk-free with your other medications; it means we don't have the information on file.
Altogether, these interactions span 4 individual medications. Because this product contains multiple hormone-altering compounds with limited safety data, it's especially important to run your exact medications through the search tool on this page before you start, and to talk with your doctor or pharmacist first if you take any cancer medications, hormone therapies, or anything else that affects estrogen or liver function.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Primordial Pro Hypertrophic Stack?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Primordial Pro Hypertrophic Stack interact with 4 drugs. Click any drug to see the details.
1 of the 4 ingredients in Primordial Pro Hypertrophic Stack interact with drugs. Each result below shows which ingredient is responsible. Androsta-3,5-Diene-7,17-Dione
AnastrozoleArimidex
How Anastrozole interacts with Primordial Pro Hypertrophic Stack — through 1 ingredient. Tap an ingredient for the detail:
Androsta-3,5-diene-7,17-dioneAromatase Inhibitors Moderate
Interaction Summary
It is believed that Arimistane inhibits the aromatase enzyme, which may interact with other aromatase inhibitors.
Read the full Androsta-3,5-diene-7,17-dione + Anastrozole interactionExemestaneAromasin
How Exemestane interacts with Primordial Pro Hypertrophic Stack — through 1 ingredient. Tap an ingredient for the detail:
Androsta-3,5-diene-7,17-dioneAromatase Inhibitors Moderate
Interaction Summary
It is believed that Arimistane inhibits the aromatase enzyme, which may interact with other aromatase inhibitors.
Read the full Androsta-3,5-diene-7,17-dione + Exemestane interactionLetrozoleFemara
How Letrozole interacts with Primordial Pro Hypertrophic Stack — through 1 ingredient. Tap an ingredient for the detail:
Androsta-3,5-diene-7,17-dioneAromatase Inhibitors Moderate
Interaction Summary
It is believed that Arimistane inhibits the aromatase enzyme, which may interact with other aromatase inhibitors.
Read the full Androsta-3,5-diene-7,17-dione + Letrozole interactionLetrozole, Ribociclib SuccinateKisqali Femara Co-Pack
How Letrozole, Ribociclib Succinate interacts with Primordial Pro Hypertrophic Stack — through 1 ingredient. Tap an ingredient for the detail:
Androsta-3,5-diene-7,17-dioneAromatase Inhibitors Moderate
Interaction Summary
It is believed that Arimistane inhibits the aromatase enzyme, which may interact with other aromatase inhibitors.
Read the full Androsta-3,5-diene-7,17-dione + Letrozole, Ribociclib Succinate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Primordial Pro Hypertrophic Stack with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Androsta-3,5-Diene-7,17-Dione
Aromatase Inhibitors
It is believed that Arimistane inhibits the aromatase enzyme, which may interact with other aromatase inhibitors. This interaction could potentially increase the risk of side effects associated with low estrogen levels or from additive side effects, such as an increased risk of liver toxicity. It is recommended to consult with a healthcare provider before combining Arimistane with other aromatase inhibitors to assess the potential risks and benefits.
Brand information
Manufacturer and brand details for Primordial Pro Hypertrophic Stack, from the product label.
Primordial Pro Hypertrophic Stack by DNA Anabolics: Common Questions
Does Primordial Pro Hypertrophic Stack by DNA Anabolics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this product tested and proven to build muscle or improve athletic performance?
Can I take this if I'm pregnant or breastfeeding?
What is Arimistane, and why is it in this product?
Are there any documented side effects from this product?
I take aromatase inhibitor cancer medication. Can I use this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Primordial Pro Hypertrophic Stack is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Primordial Pro Hypertrophic Stack’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Primordial Pro Hypertrophic Stack's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 1 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Arimistane 1 reference
- Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC