Major interaction on record — check this product against your medications before combining. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Maxi-Skin Collagen + C&A Ingredients & Drug Interactions

by Country Life

Maxi-Skin Collagen + C&A label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Maxi-Skin Collagen + C&A against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Maxi-Skin Collagen + C&A is a dietary supplement by Country Life with 4 active ingredients. Its ingredients are commonly taken for common cold and immune support, antioxidant support, skin health and collagen formation.Based on those ingredients, 494 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin A, Vitamin C. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Maxi-Skin Collagen + C&A by Country Life

Ask about any prescription or over-the-counter medication and we check it for interactions with Maxi-Skin Collagen + C&A by Country Life — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Maxi-Skin Collagen + C&A by Country Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Maxi-Skin Collagen + C&A contains 3 active ingredients: vitamin C (for immune support and collagen formation), vitamin A (for skin and eye health), and Verisol Bioactive Collagen Peptides (a hydrolyzed collagen protein). The product also contains inactive ingredients—white rice flour, stearic acid, cellulose, glycerin coating, silica, and vegetable glaze—that serve as binding and coating materials.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: skin health, elasticity and wrinkle reduction.
  • We looked for evidence on: Aging skin, Atrophic acne scars, Atopic dermatitis (eczema), Dry skin, Cellulite, Dermatoporosis — and 3 related terms.
  • The strongest evidence on file: Vitamin A is rated "Possibly Effective" for Aging skin (Natural Medicines).
  • Also on file: Collagen Peptides is rated "Possibly Effective" for Aging skin, Dry skin.
  • Also on file: Vitamin A is rated "Insufficient Reliable Evidence To Rate" for Acne, Atopic dermatitis (eczema).

Vitamin C is effective for vitamin C deficiency and possibly effective for anemia of chronic disease, atrial fibrillation, cataracts, and respiratory infections triggered by heavy exercise. Vitamin A is effective for vitamin A deficiency and possibly effective for oral leukoplakia (mouth sores), aging skin, measles, ulcerative colitis, and a lung condition in newborns.

Collagen peptides are possibly effective for aging skin and dry skin, but the evidence is insufficient to say whether they help muscle strength or acne.

The evidence, ingredient by ingredient Vitamin C Vitamin A Collagen Peptides

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin C is generally well tolerated at normal supplement doses; side effects like stomach cramps, heartburn, and osmotic diarrhea are more likely above 2 grams daily. High-dose vitamin C can raise the risk of kidney stones in susceptible people.

Vitamin A is safe at recommended amounts but builds up in your body and can become toxic at high doses, causing liver damage, headache, and skin problems. In pregnancy, normal dietary amounts are needed, but high-dose supplements of either vitamin—especially vitamin A—should be avoided because they may cause birth defects.

Collagen peptides are generally well tolerated; nausea, indigestion, and diarrhea are rare. There isn't enough safety data on collagen peptides in pregnancy or while breastfeeding, so talk with your doctor before using if you're pregnant or nursing.

Side effects, ingredient by ingredient Vitamin C Vitamin A Collagen Peptides

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Vitamin A, Vitamin C.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; cancer treatments.
  • For scale: 495 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Major interaction: don't combine with retinoids like isotretinoin or tretinoin without a pharmacist's go-ahead. Moderate interactions to double-check: estrogens (birth control, hormone therapy), warfarin or other blood thinners, tetracycline antibiotics, chemotherapy drugs, levothyroxine (thyroid medicine), fluphenazine (an antipsychotic), indinavir (an HIV drug), and aluminum-containing products.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product pairs vitamins A and C with collagen for skin health and is possibly effective for aging and dry skin. If you take birth control, hormone therapy, warfarin, tetracycline antibiotics, or any retinoid (like Accutane or tretinoin cream), check with your pharmacist first—the vitamin A and C here can interact.

Anyone prone to kidney stones should be cautious with the vitamin C dose.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maxi-Skin Collagen + C&A, straight from the product label.

Brand Country Life
Barcode (UPC) 015794450603
Net contents 108 Tablet(s)
Market status On market
Date entered into DSLD Feb 23, 2018
DSLD ID 82032
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maxi-Skin Collagen + C&A by Country Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Tablet(s)
Maximum serving Sizes:
3 Tablet(s)
Servings per container
36
UPC/BARCODE
015794450603
IngredientAmount% DV
Calories10 Calorie(s)--
Protein2 Gram(s)--
Vitamin C60 mg100%
Vitamin A1000 IU20%
Verisol Bioactive Collagen Peptides2500 mg--

Other ingredients: organic White Rice flour, Stearic Acid, Cellulose & Glycerin Coating, Silica, Vegetable Glaze

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Leveraging over 20 years of development expertise in hair, skin and nail supplements, Country Life introduces Maxi-Skin, Collagen + C&A with clinically studied Verisol collagen.

Clinically studied Verisol Bioactive Collagen Peptides enhance skin elasticity, increase skin collagen by 60% and reduce depth of eye wrinkles.

Randomized, double-blind, placebo-controlled studies with daily intake of 2.5 grams Verisol collagen in women 35-55 years (measured skin elasticity at 4 weeks) and in women 45-65 years (measured eye wrinkle volume at 4 weeks and skin collagen enhancement at 8 weeks). Study results compared Verisol collagen to placebo. Individual results may vary.

Verisol Beauty from Within

Whole foods market Exclusive Only here

Verisol and Bioactive Collagen Peptides are registered trademarks of GELITA AG.

FSC www.fsc.org Recycled Packaging made from recycled material FSC C005506

To bring life back to your hair, skin and nails, also try...Maxi-Hair Plus Healthier hair & nails Supports strong nails

Maxi-Skin, Collagen + C&A, with Verisol collagen improves skin appearance, through a Tri-Layer approach.

Maxi-Skin, Collagen + C&A with Versiol collagen helps replenish natural collagen production, improving the appearance and smoothness of your skin.

It contains: Clinically studied Verisol Bioactive Collagen Peptides

By affecting the collagen metabolism directly from the inside, via collagen peptides, Maxi-Skin, Collagen + C&A is able to help reduce the appearance of wrinkles and increase skin elasticity.

General Statements

This proprietary blend supports all three layers of the skin.

Vitamin C protects skin from cell-damaging free radicals while Vitamin A helps epidermal cell renewal.

Yes recyclable packaging Yes manufacturing supports wind power

Established 1971

Tri-Layer

20% more free

Our pledge of integrity Authenticity Cleanliness Freshness Consistency Accuracy

Color variation or speckling is natural for this product.

This product has been manufactured at a GMP registered facility.

Country Life is passionate about helping you live a healthy, active life. This extends into the environment we live in and the materials we use in our packaging. We use 100% recycled paperboard.

Please help us in our mission; recycle this box & bottle after use.

Skin is composed of 3 layers: Epidermis, dermis, and hypodermis.

Epidermi Dermis Hypodermis Collagen Cosmetic products work primarily on the top layer of the skin, the epidermis, reinforcing skin's barrier function and improving its protective abilities. However, the visible signs of aging, like fine lines and wrinkles, decreased elasticity, firmness, and dryness, are all symptoms of what's happening beneath the surface - in the skin's dermal layer.

Over time the skin's essential supportive structure starts to break down. Collagen levels decline and elastin loses its spring causing fine lines and wrinkles to appear on the skin's surface. The older we get and the more exposed our skin has been to stressors like pollution and UV light, the more we need extra help to support smooth and supple skin.

Enhance skin elasticity Positive results last up to 4 weeks after intake is stopped unlike topical creams Increase skin collagen by 60% Significantly reduce depth of eye wrinkles

At Country Life, integrity is our # 1 ingredient. Every product is rigorously tested to ensure it measures up against Country Life's 5 integrity standards: 1) authenticity of ingredients; 2) cleanliness of ingredients; 3) freshness of ingredients; 4) consistency of the formula; and 5) accuracy of labeling. Go to CountryLifeVitamins.com to learn more.

04D17NM

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Yes Certified Gluten-free by GFCO.org

No yeast, wheat or soy No milk or salt No preservatives No artificial colors, flavor or sweeteners No Magnesium Stearate No GMOs

Certified Gluten-free

100% bovine collagen, BSE-free.

Formula

Includes Verisol collagen clinically shown to: Enhance elasticity Increase collagen by 60% Reduce depth of wrinkles

100% bovine collagen, BSE-free.

Vitamin C Protects skin cells from cell-damaging free radicals Required for the formation of collagen in dermis layer

Vitamin A Essential for skin cell renewal in the epidermis layer

Maxi-Skin Collagen + C&A

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take three (3) tablets once daily.

Precautions

As a reminder, discuss the supplements and medications that you take with your health care providers.

Do not accept if seal is broken.

Keep out of the reach of children.

Caution: If you are pregnant or nursing, taking medication or planning a surgery, consult your doctor before using this product.

If any adverse reaction occur, stop taking the product and consult your doctor.

Storage

Store in a dry place between 59(0)-86(0) F.

General

Product No. 45060 04D17NY

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Maxi-Skin Collagen + C&A by Country Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Maxi-Skin Collagen + C&A label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Maxi-Skin Collagen + C&A by Country Life

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Tablet(s) Dosage formTablet Or Pill Servings per container36 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

2 Gram(s) per serving

Vitamin C

Interacts with
207 drugs
60 mg per serving Form: Ascorbic Acid

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...

Vitamin C monograph & interactions

Vitamin A

Interacts with
387 drugs
1000 IU per serving Form: Retinyl Palmitate

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplemen...

Vitamin A monograph & interactions

Verisol Bioactive Collagen Peptides

No known
interactions
2500 mg per serving

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is...

Verisol Bioactive Collagen Peptides monograph & interactions

Other (inactive) ingredients: Organic White Rice flour, Stearic Acid, Cellulose & Glycerin Coating, Silica, Vegetable Glaze. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maxi-Skin Collagen + C&A by Country Life Drug Interactions

Want to check YOUR meds against Maxi-Skin Collagen + C&A?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
494Drugs
9 Major 452 Moderate 33 Minor

Ingredients driving the most interactions

Vitamin A 387
Vitamin C 207

Individual Drug Interactions

The ingredients in Maxi-Skin Collagen + C&A interact with 494 drugs. Click any drug to see the details.

2 of the 4 ingredients in Maxi-Skin Collagen + C&A interact with drugs. Each result below shows which ingredient is responsible. Vitamin A Vitamin C

Each ingredient & the kinds of drugs it affects

For each ingredient in Maxi-Skin Collagen + C&A with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin A4 drug types · 387 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D
Vitamin A full monograph & interactions

Vitamin C13 drug types · 207 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Aluminum

Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.

Likelihood Probable Evidence B
Antitumor Antibiotics

Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Estrogens

Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.

Likelihood Probable Evidence B
Fluphenazine (Prolixin)

Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.

Likelihood Possible Evidence D
Indinavir (Crixivan)

Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.

Likelihood Probable Evidence B
Warfarin (Coumadin)

High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.

Likelihood Probable Evidence B
Aspirin

Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.

Likelihood Possible Evidence B
Choline Magnesium Trisalicylate (Trilisate)

Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Niacin

Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Salsalate (Disalcid)

Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Vitamin C full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Maxi-Skin Collagen + C&A, from the product label.

Country Life

See all Country Life products
Name
Country Life, LLC
Street Address
180 Vanderbilt Motor Parkway
City
Hauppauge
State
NY
ZipCode
11788
Web Address
CountryLifeVitamins.com
Pharmacist Counseling Corner

Maxi-Skin Collagen + C&A by Country Life: Common Questions

Does Maxi-Skin Collagen + C&A by Country Life interact with any medications?
Yes. Based on its ingredients, Maxi-Skin Collagen + C&A has a known interaction with 494 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Maxi-Skin Collagen + C&A contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or breastfeeding?
Normal dietary amounts of vitamins A and C are needed in pregnancy, but high-dose supplements—especially of vitamin A—can cause birth defects and should be avoided unless your doctor advises otherwise. There isn't enough safety data on collagen peptides during pregnancy or breastfeeding, so talk with your pharmacist or doctor for personalized advice.
What does the collagen peptide do in this product?
Collagen peptides are a hydrolyzed protein that's possibly effective for aging skin and dry skin. The evidence is insufficient to say whether they help with muscle strength or acne.
Can this cause stomach upset?
Vitamin C at high doses can trigger stomach cramps, heartburn, and diarrhea, especially above 2 grams daily. Collagen peptides rarely cause nausea or indigestion. Start with a lower dose if your stomach is sensitive.
What does vitamin A do in this product?
Vitamin A supports skin, eye, and immune health. It's effective for vitamin A deficiency and possibly effective for aging skin, oral sores, and other conditions. It's a fat-soluble vitamin that builds up in your body, so very high doses can become toxic.
Can I take this with my thyroid medicine?
Vitamin C in this product may increase how much levothyroxine (Synthroid) your body absorbs. Talk with your pharmacist about the timing of your doses—you may need to space them apart to keep your thyroid levels stable.
Is this safe if I'm prone to kidney stones?
High-dose vitamin C raises kidney stone risk in people prone to them. This product contains vitamin C, so check with your pharmacist about whether the dose is safe for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maxi-Skin Collagen + C&A is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maxi-Skin Collagen + C&A label
Go deeper

The Full Monographs Behind Maxi-Skin Collagen + C&A’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin C

Interacts with 207 drugs

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...

Read the full Vitamin C monograph → Herb & supplement monograph

Vitamin A

Interacts with 387 drugs

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplements are mainly useful for correcting a tr...

Read the full Vitamin A monograph → Herb & supplement monograph

Collagen Peptides

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is still developing and results vary. They...

Read the full Collagen Peptides monograph →
Sources

Sources & How We Checked

Maxi-Skin Collagen + C&A's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 84 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin C 51 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
  3. Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
  4. Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
  5. Dwyer JH, Merz NB, Shirocre AM, et al. Progression of early atherosclerosis and intake of vitamin C and vitamin E from supplements and food. The Los Angeles Atherosclerosis Study. 41st Annual Conference on Cardiovascular Disease Epidemiology and Prevent
  6. Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA 1999;281:1415-23. PubMed
  7. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  8. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
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See these in context on the Vitamin A monograph →

Collagen Peptides 2 references
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See these in context on the Collagen Peptides monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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