Mega Acidophilus Ingredients & Drug Interactions
by Wonder Labs
What is this page for?
First and foremost: checking Mega Acidophilus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Mega Acidophilus is a dietary supplement by Wonder Labs with 5 active ingredients. Its ingredients are commonly taken for diarrhea relief, constipation and digestive health, cholesterol support.Based on those ingredients, 188 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus, Lactobacillus helveticus, Citrus Pectin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Mega Acidophilus by Wonder Labs
Ask about any prescription or over-the-counter medication and we check it for interactions with Mega Acidophilus by Wonder Labs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Mega Acidophilus by Wonder Labs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Mega Acidophilus contains five active probiotic and prebiotic ingredients. The product includes three Lactobacillus species—acidophilus, helveticus, and salivarius—which are beneficial bacteria meant to support digestive health.
It also contains Bifidobacterium animalis lactis, another helpful probiotic strain, and Citrus Pectin, a soluble fiber that acts as a prebiotic (food for the good bacteria). The capsules are made with vegetable cellulose and include vegetable magnesium stearate, ascorbic acid, and silica as inactive ingredients.
Does it work?
Moderate evidence
The evidence supporting this product's ingredients is mixed. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.
Citrus Pectin is possibly effective for high cholesterol. However, we have no reliable evidence that Lactobacillus helveticus works for any of the conditions tested—allergic rhinitis, antibiotic-associated diarrhea, cognitive function, depression, rotaviral diarrhea, and exercise-induced respiratory infections all fall short of established proof.
Effectiveness data isn't on file for Bifidobacterium animalis lactis or Lactobacillus salivarius.
How safe is it?
Well-documented data
Lactobacillus acidophilus is generally well tolerated in healthy adults and children. The most common side effects from probiotics are mild gastrointestinal symptoms—gas, bloating, abdominal pain, diarrhea, or burping—though these are uncommon.
A rare but serious concern with live probiotic bacteria is infection; cases of bacteremia, sepsis, and other infections have been reported, usually in people with already-compromised health or translocation from other body sites. Citrus Pectin is generally well tolerated, with occasional gas, loose stools, or mild cramps.
Rarely, sensitive individuals may have allergic reactions including anaphylaxis. Because limited safety data exist for these probiotics in pregnancy and lactation, check with your doctor or pharmacist before use if you are pregnant or breastfeeding.
Meds to double-check
Moderate interaction found
Before you start Mega Acidophilus, check with your doctor or pharmacist if you take any antibiotic drugs (Moderate risk—the probiotics are live organisms and antibiotics can kill them), digoxin or Lanoxin (Moderate risk—pectin may reduce absorption), lovastatin or Mevacor (Moderate risk—pectin may lower its effectiveness), or tetracycline antibiotics (Moderate risk—pectin may reduce absorption). Your healthcare provider can advise whether to space out doses or choose a different approach.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Mega Acidophilus may help with certain digestive conditions, especially irritable bowel syndrome and antibiotic-associated diarrhea, though the evidence for some ingredients is limited or absent. If you take antibiotics, digoxin, lovastatin, or tetracycline antibiotics, this product could reduce how well those medications work—separate timing or avoid it altogether, and talk it over with your doctor or pharmacist before starting.
People who are seriously ill or immunocompromised should also check with their healthcare provider first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Mega Acidophilus, straight from the product label.
| Brand | Wonder Labs |
|---|---|
| Barcode (UPC) | 099528942053 |
| Net contents | 500 Vegetable Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Dec 18, 2021 |
| DSLD ID | 262369 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Mega Acidophilus by Wonder Labs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lactobacillus acidophilus | 0 NP | -- |
| Bifidobacterium animalis lactis | 0 NP | -- |
| Citrus Pectin | 200 mg | -- |
| Lactobacillus helveticus | 0 NP | -- |
| Lactobacillus salivarius | 0 NP | -- |
| Proprietary Blend of Cultures | 80 mg | -- |
Other ingredients: Vegetable Cellulose, Vegetable Magnesium Stearate, L-Ascorbic Acid, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take 2 vegetable capsules daily, preferably with a meal. 6 billion good bacteria per 2 capsules serving at time of manufacture.
Precautions
Tamper Evident: Do not use this product if imprinted for seal under cap is broken or missing.
Keep out of reach of children.
Caution: If you are pregnant or nursing, consult your physician before taking this product.
Contains milk ingredients
Storage
Keep tightly closed. Refrigerate after opening
Formulation
Contain no artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no soy, no gluten, no wheat, no fish. Sodium free. Non-GMO Gluten free
Nutritionally supports healthy intestinal flora
Seals/Symbols
FDA Registered Facility GMP Certified Good Manufacturing Practice USA Made
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
6 billion good bacteria Freeze-Dried Probiotic with Pectin
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
Home of the World Famous Valerin
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Mega Acidophilus by Wonder Labs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Mega Acidophilus by Wonder Labs
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Vegetable Capsule(s) Dosage formCapsule Servings per container250 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Citrus Pectin
Interacts with23 drugs
Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...
Citrus Pectin monograph & interactionsProprietary Blend of Cultures
- › Lactobacillus acidophilus
- › Bifidobacterium animalis lactis
- › Lactobacillus helveticus
- › Lactobacillus salivarius
Other (inactive) ingredients: Vegetable Cellulose, Vegetable Magnesium Stearate, L-Ascorbic Acid, Silica. These complete the product’s ingredient list but are not active constituents.
Mega Acidophilus by Wonder Labs Drug Interactions
HelloPharmacist Interaction Report
Mega Acidophilus by Wonder Labs contains three ingredients with documented drug interactions: Lactobacillus acidophilus, Citrus Pectin, and Lactobacillus helveticus.
The most serious concern is a moderate interaction between Citrus Pectin and digoxin (Lanoxin), a heart medication—pectin may reduce digoxin absorption by around 62%, potentially decreasing how well it works to control your heartbeat.
Read the full breakdown — every affected drug type, severity by severity
Both Lactobacillus acidophilus and Lactobacillus helveticus interact with antibiotic drugs (Moderate severity). Since these probiotics are live organisms, antibiotics taken at the same time can kill them off and reduce the probiotic's effectiveness.
Citrus Pectin also has moderate interactions with tetracycline antibiotics and lovastatin (Mevacor), a cholesterol medication—it may reduce how much of these drugs your body absorbs, making them less effective.
We could not check two of the five active ingredients—Bifidobacterium animalis lactis and Lactobacillus salivarius—because we hold no interaction data for them. Altogether, these interactions span 188 individual medications.
Use the search tool on this page to check your exact medications before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Mega Acidophilus?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Mega Acidophilus interact with 188 drugs. Click any drug to see the details.
3 of the 5 ingredients in Mega Acidophilus interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus Lactobacillus helveticus Citrus Pectin
Niacin, LovastatinAdvicor
How Niacin, Lovastatin interacts with Mega Acidophilus — through 1 ingredient. Tap an ingredient for the detail:
Citrus PectinLovastatin (mevacor) Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Read the full Citrus Pectin + Niacin, Lovastatin interactionNitrofurantoinFuradantin, Furatoin, Macrobid, Macrodantin
How Nitrofurantoin interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Nitrofurantoin interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Nitrofurantoin interactionNorfloxacinNorflox, Noroxin
How Norfloxacin interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Norfloxacin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Norfloxacin interactionOfloxacinFloxin, Floxin Injection, Floxin Otic, Oflox
How Ofloxacin interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Ofloxacin interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Ofloxacin interactionOmadacycline (iv)Nuzyra
How Omadacycline (iv) interacts with Mega Acidophilus — through 1 ingredient. Tap an ingredient for the detail:
Citrus PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Citrus Pectin + Omadacycline (iv) interactionOmadacycline (oral)Nuzyra
How Omadacycline (oral) interacts with Mega Acidophilus — through 1 ingredient. Tap an ingredient for the detail:
Citrus PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Citrus Pectin + Omadacycline (oral) interactionOritavancin DiphosphateKimyrsa, Orbactiv
How Oritavancin Diphosphate interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Oritavancin Diphosphate interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Oritavancin Diphosphate interactionOxacillinBactocill, Prostaphlin
How Oxacillin interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Oxacillin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Oxacillin interactionOxytetracyclineTerramycin
How Oxytetracycline interacts with Mega Acidophilus — through 3 ingredients. Tap an ingredient for the detail:
Citrus PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Citrus Pectin + Oxytetracycline interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Oxytetracycline interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Oxytetracycline interactionOxytetracycline, Phenazopyridine, SulfamethizoleUrobiotic
How Oxytetracycline, Phenazopyridine, Sulfamethizole interacts with Mega Acidophilus — through 3 ingredients. Tap an ingredient for the detail:
Lactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Oxytetracycline, Phenazopyridine, Sulfamethizole interactionCitrus PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Citrus Pectin + Oxytetracycline, Phenazopyridine, Sulfamethizole interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Oxytetracycline, Phenazopyridine, Sulfamethizole interactionOzenoxacinXepi
How Ozenoxacin interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Ozenoxacin interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Ozenoxacin interactionParomomycin SulfateHumatin
How Paromomycin Sulfate interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Paromomycin Sulfate interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Paromomycin Sulfate interactionPenicillin GPfizerpen
How Penicillin G interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Penicillin G interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Penicillin G interactionPenicillin G BenzathineBicillin L-A, Permapen
How Penicillin G Benzathine interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Penicillin G Benzathine interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Penicillin G Benzathine interactionPenicillin G Benzathine, ProcaineBicillin C-R
How Penicillin G Benzathine, Procaine interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Penicillin G Benzathine, Procaine interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Penicillin G Benzathine, Procaine interactionPenicillin G PotassiumPen-Tids, Pentids, Pentids 400, Pentids 800, Wycillin
How Penicillin G Potassium interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Penicillin G Potassium interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Penicillin G Potassium interactionPenicillin G, ProcainePenicillin G Procaine
How Penicillin G, Procaine interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Penicillin G, Procaine interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Penicillin G, Procaine interactionPenicillin VPen-Vee
How Penicillin V interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Penicillin V interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Penicillin V interactionPenicillin V PotassiumBeepen-VK, Ledercillin, Pen VK, Pen-Vee K, V-Cillin K, Veetids
How Penicillin V Potassium interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Penicillin V Potassium interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Penicillin V Potassium interactionPenicillin VkRobicillin
How Penicillin Vk interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Penicillin Vk interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Penicillin Vk interactionPentamidinePentam 300
How Pentamidine interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Pentamidine interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Pentamidine interactionPhenazopyridine, SulfamethizoleThiosulfil-A, Thiosulfil-A Forte
How Phenazopyridine, Sulfamethizole interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Phenazopyridine, Sulfamethizole interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Phenazopyridine, Sulfamethizole interactionPhenazopyridine, SulfisoxazoleAzo-Gantrisin
How Phenazopyridine, Sulfisoxazole interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Phenazopyridine, Sulfisoxazole interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Phenazopyridine, Sulfisoxazole interactionPiperacillinPipracil
How Piperacillin interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Piperacillin interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Piperacillin interactionPiperacillin , TazobactamZosyn
How Piperacillin , Tazobactam interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Piperacillin , Tazobactam interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Piperacillin , Tazobactam interactionPivampicillinPondicillin
How Pivampicillin interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Pivampicillin interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Pivampicillin interactionPivmecillinamSelexid
How Pivmecillinam interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Pivmecillinam interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Pivmecillinam interactionPlazomicin SulfateZemdri
How Plazomicin Sulfate interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Plazomicin Sulfate interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Plazomicin Sulfate interactionPretomanidPretomanid
How Pretomanid interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Pretomanid interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Pretomanid interactionPyrazinamideTebrazid
How Pyrazinamide interacts with Mega Acidophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Pyrazinamide interactionLactobacillus HelveticusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Helveticus + Pyrazinamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Mega Acidophilus with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Lactobacillus acidophilus
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Lactobacillus helveticus
Antibiotic Drugs
Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L. helveticus.
Lactobacillus helveticus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. helveticus preparations by at least two hours.
Citrus Pectin
Digoxin (Lanoxin)
Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.
Lovastatin (Mevacor)
Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.
Tetracycline Antibiotics
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.
Brand information
Manufacturer and brand details for Mega Acidophilus, from the product label.
Wonder Labs
See all Wonder Labs products- Name
- Wonder Labs
- Street Address
- 115 S.C.T. Court
- City
- White House
- State
- TN
- ZipCode
- 37188
- Phone Number
- 800.992.1672
- Web Address
- www.wonderlabs.com
Mega Acidophilus by Wonder Labs: Common Questions
Does Mega Acidophilus by Wonder Labs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
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Will this help with my irritable bowel syndrome or IBS?
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Is it safe to take this if I'm pregnant?
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Does this contain any fillers or other inactive ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Mega Acidophilus’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Pectin
Interacts with 23 drugsPectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...
Read the full Pectin monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph → Herb & supplement monographLactobacillus Helveticus
Interacts with 182 drugsLactobacillus helveticus is a lactic acid bacterium used as a probiotic, often combined with other strains in mood, gut, and general wellness products. Early research is interesting—especial...
Read the full Lactobacillus Helveticus monograph →Sources & How We Checked
Mega Acidophilus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 28 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Pectin 11 references
- Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
- Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
- Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
- Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
- Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
- Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
- Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
- Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
- Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed
Lactobacillus Helveticus 2 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
See these in context on the Lactobacillus Helveticus monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC