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Dietary supplement

Met-Gen Ingredients & Drug Interactions

by Genestra Brands

Met-Gen label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Met-Gen against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Met-Gen is a dietary supplement by Genestra Brands with 3 active ingredients. Its ingredients are commonly taken for memory and concentration, digestive upset, hair growth.Based on those ingredients, 372 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rosemary (Rosmarinus officinalis) young shoot extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Met-Gen by Genestra Brands

Ask about any prescription or over-the-counter medication and we check it for interactions with Met-Gen by Genestra Brands — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Met-Gen by Genestra Brands

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Met-Gen is a liquid supplement with 3 active ingredients: rosemary young shoot extract, olive young shoot extract, and almond bud extract. These plant extracts are mixed with purified water, ethanol, and glycerin.

The rosemary is the ingredient carrying documented drug interactions; the other two have not shown interaction concerns in our data.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

  • Memory via Rosemary Possibly Effective
Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Memory — rated "Possibly Effective" (Rosemary) (Natural Medicines).

For rosemary, the evidence shows it's possibly effective for memory. For the other conditions listed — including age-related cognitive decline, alopecia areata, and nonalcoholic fatty liver disease — the evidence is insufficient to rate.

Olive extract and almond bud extract don't have established effectiveness ratings in the data we hold for any condition.

The evidence, ingredient by ingredient Rosemary Olive Sweet Almond

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rosemary is safe in normal culinary amounts, but concentrated extracts require caution. In large or medicinal doses, rosemary should be avoided during pregnancy and breastfeeding because there isn't enough safety data.

Olive extract is less studied in concentrated supplement form than as food; avoid concentrated supplements unless your doctor approves. Almond is generally safe as food if you're not allergic, and eating normal amounts is considered safe in pregnancy and breastfeeding for people without tree-nut allergies — but tree nuts are a major food allergen.

Rare adverse effects from rosemary include allergic skin reactions, lip and gum swelling, occupational asthma in sensitive individuals, and photosensitivity. Olive may cause headache and stomach discomfort.

Almond's main risk is allergic reaction in those with tree-nut allergies.

Side effects, ingredient by ingredient Rosemary Olive Sweet Almond

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Rosemary.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 372 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting Met-Gen, double-check your blood thinners or antiplatelet medications (like warfarin, apixaban, or clopidogrel), aspirin-type pain relievers, diabetes drugs, and any medications that rely on the liver enzyme CYP1A2 to work. Rosemary is the ingredient behind these interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Consider Met-Gen if you're looking for a memory support supplement and have no allergies to tree nuts. If you take blood thinners, antiplatelet drugs, diabetes medications, or salicylate-containing pain relievers, check with your pharmacist first — rosemary can interact with these.

Talk to your pharmacist or doctor about whether this product fits your health plan, especially if you're pregnant, breastfeeding, or have a tree-nut allergy.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Met-Gen, straight from the product label.

Brand Genestra Brands
Barcode (UPC) 883196109210
Net contents 0.5 Fluid Ounce(s); 15 mL
Market status On market
Date entered into DSLD Mar 25, 2021
DSLD ID 244251
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Met-Gen by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.28 mL
Maximum serving Sizes:
0.28 mL
Servings per container
53
UPC/BARCODE
883196109210
IngredientAmount% DV
Rosemary (Rosmarinus officinalis) young shoot extract0.09 mL--
Olive (Olea europaea) young shoot extract0.09 mL--
Almond (Prunus dulcis) bud extract0.09 mL--

Other ingredients: purified Water, Ethanol, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Dose: Take 10 drops once daily or as recommended by your health professional. Invert bottle to 45 degrees and shake lightly allowing drops to fall directly into mouth or in 1/4 oz of water.

General Statements

For warnings and additional information, see outer box.

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Phyto-gen

Scan to learn about our quality excellence

Precautions

Keep out of the reach of children.

Use only if safety seal is intact.

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

This product was sealed for your protection. Do not use if box or contents are open or damaged.

Storage

Store in a cool, dry place.

Formulation

Made in France for Seroyal USA

FDA Statement of Identity

Dietary Supplement

Formula

Olive Almond Rosemary

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Met-Gen by Genestra Brands label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Met-Gen label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Met-Gen by Genestra Brands

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.28 mL Dosage formLiquid Servings per container53 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Rosemary (Rosmarinus officinalis) young shoot extract

Interacts with
372 drugs
0.09 mL per serving

Rosemary is a fragrant Mediterranean herb that is safe and flavorful in normal food amounts. Some early research suggests possible benefits for memory...

Rosemary (Rosmarinus officinalis) young shoot extract monograph & interactions

Olive (Olea europaea) young shoot extract

No known
interactions
0.09 mL per serving

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...

Olive (Olea europaea) young shoot extract monograph & interactions

Almond (Prunus dulcis) bud extract

No known
interactions
0.09 mL per serving

Sweet almonds are a nutritious tree nut rich in healthy fats, fiber, protein, vitamin E, and minerals, and they are generally safe and healthy to eat...

Almond (Prunus dulcis) bud extract monograph & interactions

Other (inactive) ingredients: Purified Water, Ethanol, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Met-Gen by Genestra Brands Drug Interactions

Want to check YOUR meds against Met-Gen?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
372Drugs
212 Moderate 160 Minor

Ingredients driving the most interactions

Rosemary (Rosmarinus officinalis) young shoot extract 372

Individual Drug Interactions

The ingredients in Met-Gen interact with 372 drugs. Click any drug to see the details.

1 of the 3 ingredients in Met-Gen interact with drugs. Each result below shows which ingredient is responsible. Rosemary (Rosmarinus officinalis) young shoot extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Met-Gen with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Rosemary (Rosmarinus officinalis) young shoot extract6 drug types · 372 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that rosemary inhibits platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that rosemary extract can decrease blood glucose levels in diabetic models. However, research in humans is conflicting. Although rosemary powder decreased blood glucose levels in healthy adults, no change in blood glucose levels was seen in adults with type 2 diabetes, most of whom were taking antidiabetes drugs.

Likelihood Possible Evidence B
Aspirin

Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Rosemary is reported to contain salicylates.

Likelihood Possible Evidence D
Choline Magnesium Trisalicylate (Trilisate)

Theoretically, rosemary might have additive effects with salicylate-containing drugs such as choline magnesium trisalicylate.
Rosemary is reported to contain salicylate.

Likelihood Possible Evidence D
Salsalate (Disalcid)

Theoretically, rosemary might have additive effects with salicylate-containing drugs such as salsalate.
Rosemary is reported to contain salicylate.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that rosemary induces CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Unlikely Evidence D
Rosemary (Rosmarinus officinalis) young shoot extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Met-Gen, from the product label.

Genestra Brands

Name
Seroyal USA
City
Pittsburgh
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Web Address
seroyal.com
Pharmacist Counseling Corner

Met-Gen by Genestra Brands: Common Questions

Does Met-Gen by Genestra Brands interact with any medications?
Yes. Based on its ingredients, Met-Gen has a known interaction with 372 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Met-Gen contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does rosemary in this product raise my bleeding risk if I'm on aspirin?
Rosemary contains salicylates and may add to aspirin's blood-thinning effects, increasing bleeding risk. This is a Moderate concern. Talk to your pharmacist or doctor before combining them.
Can I take Met-Gen if I have a tree-nut allergy?
No. This product contains almond bud extract, and tree nuts are a major food allergen. If you have a tree-nut allergy, avoid this supplement.
Is it safe to use this while I'm pregnant?
Food amounts of rosemary and almonds are considered safe in pregnancy if you're not allergic, but medicinal doses — like those in this concentrated supplement — should be avoided because there isn't enough safety data. Talk to your doctor before taking it.
What are the most common side effects?
Olive extract may cause headache and stomach discomfort. Almond's main concern is allergic reaction in those with tree-nut sensitivity. Rosemary can rarely cause allergic skin reactions or lip and gum swelling.
Does this supplement actually help with memory?
Rosemary, one of the three active ingredients, is possibly effective for memory based on the evidence we hold. The effectiveness of olive and almond extracts for any condition isn't established in our data.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Met-Gen label
Go deeper

The Full Monographs Behind Met-Gen’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rosemary

Interacts with 372 drugs

Rosemary is a fragrant Mediterranean herb that is safe and flavorful in normal food amounts. Some early research suggests possible benefits for memory, mood, and hair growth, but the evidenc...

Read the full Rosemary monograph → Herb & supplement monograph

Olive

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyrosol. Olive oil as part of a Mediterrane...

Read the full Olive monograph → Herb & supplement monograph

Sweet Almond

Sweet almonds are a nutritious tree nut rich in healthy fats, fiber, protein, vitamin E, and minerals, and they are generally safe and healthy to eat as part of a balanced diet. Almond oil i...

Read the full Sweet Almond monograph →
Sources

Sources & How We Checked

Met-Gen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rosemary 20 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  5. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  6. Cartier LC, Lehrer A, Malo JL. Occupational asthma caused by aromatic herbs. Allergy 1996;51:647-9. DOI
  7. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. PubMed
  8. Swain AR, Dutton SP, Truswell AS. Salicylates in foods. J Am Diet.Assoc 1985;85(8):950-60. DOI
  9. Zhu BT, Loder DP, Cai MX, et al. Dietary administration of an extract from rosemary leaves enhances the liver microsomal metabolism of endogenous estrogens and decreases their uterotropic action in CD-1 mice. Carcinogenesis 1998;19(10):1821-7. PubMed
  10. Debersac P, Heydel JM, Amiot MJ, et al. Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: description of specific patterns. Food Chem Toxicol 2001;39(9):907-18. PubMed
  11. Debersac P, Vernevaut MF, Amiot MJ, et al. Effects of a water-soluble extract of rosemary and its purified component rosmarinic acid on xenobiotic-metabolizing enzymes in rat liver. Food Chem Toxicol 2001;39(2):109-17. PubMed
  12. Lee JJ, Jin YR, Lee JH, et al. Antiplatelet activity of carnosic acid, a phenolic diterpene from Rosmarinus officinalis. Planta Med 2007;73(2):121-7.
  13. Yamamoto J, Yamada K, Naemura A, et al. Testing various herbs for antithrombotic effect. Nutrition 2005;21(5):580-7. PubMed
  14. Naemura A, Ura M, Yamashita T, et al. Long-term intake of rosemary and common thyme herbs inhibits experimental thrombosis without prolongation of bleeding time. Thromb Res 2008;122(4):517-22. PubMed
  15. Lee JJ, Jin YR, Lim Y, et al. Antiplatelet activity of carnosol is mediated by the inhibition of TXA2 receptor and cytosolic calcium mobilization. Vascul Pharmacol 2006;45:148-53. PubMed
  16. Bakirel, T., Bakirel, U., Keles, O. U., Ulgen, S. G., and Yardibi, H. In vivo assessment of antidiabetic and antioxidant activities of rosemary (Rosmarinus officinalis) in alloxan-diabetic rabbits. J Ethnopharmacol 2-28-2008;116(1):64-73. PubMed
  17. Erenmemisoglu, A., Saraymen, R., and Ustun, S. Effect of a Rosmarinus officinalis leave extract on plasma glucose levels in normoglycaemic and diabetic mice. Pharmazie 1997;52(8):645-646.
  18. Valones MAA, Silva ICG, Gueiros LAM, Leão JC, Caldas AF Jr, Carvalho AAT. Clinical assessment of rosemary-based toothpaste (Rosmarinus officinalis Linn.): A randomized controlled double-blind study. Braz Dent J. 2019;30(2):146-151. PubMed
  19. Quirarte-Báez SM, Zamora-Perez AL, Reyes-Estrada CA, et al. A shortened treatment with rosemary tea (rosmarinus officinalis) instead of glucose in patients with diabetes mellitus type 2 (TSD). J Popul Ther Clin Pharmacol. 2019;26(4):e18-e28.
  20. Al Jamal A. Effect of rosemary (Rosmarinus officinalis) on lipid profiles and blood glucose in human diabetic patients (type-2). African J. Biochem. Res. 2014;8(8):147-50. DOI

See these in context on the Rosemary monograph →

Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

See these in context on the Olive monograph →

Sweet Almond 4 references
  1. Motaharifard MS, Effatpanah M, Karimi M, et al. Effect of sweet almond syrup versus methylphenidate in children with ADHD: A randomized triple-blind clinical trial. Complement Ther Clin Pract. 2019;36:170-175. PubMed
  2. Simon D, Nobbe S, Nägeli M, et al. Short- and long-term effects of two emollients on itching and skin restoration in xerotic eczema. Dermatol Ther. 2018;31(6):e12692. PubMed
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor
  4. Salama M, Tebben PJ, Al Nofal A. An infant developing hypercalcemia and hypophosphatemia due to the use of exclusively almond milk. J Pediatr Endocrinol Metab 2024;37(4):375-379. PubMed

See these in context on the Sweet Almond monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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