No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Moducare Ingredients & Drug Interactions

by Moducare

Tablet Or Pill Category: Fat/fatty Acid
No known interaction
The interaction bottom line No known interaction

Moducare is a dietary supplement by Moducare with 4 active ingredients. Its ingredients are commonly taken for tooth decay prevention, dry mouth, sugar substitute.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Moducare by Moducare

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “Moducare” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Moducare has 3 active ingredients. Xylitol is a sugar alcohol used to help prevent tooth decay.

Plant Sterols are compounds from plants that help lower cholesterol by blocking how much cholesterol your body absorbs from food. Plant Sterolins — we don't have data on file for this one.

The tablet also contains several inactive ingredients like microcrystalline cellulose (a binder), inulin, and flavoring.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: restore strengthen and balance immune system.
  • We looked for evidence on: Coronavirus disease 2019 (COVID-19), Cystic fibrosis, Gulf war syndrome, Hematopoietic stem cell transplant (HSCT), Upper respiratory tract infection (URTI), Immune function — and 2 related terms.
  • The closest evidence on file: Xylitol is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI) (Natural Medicines).
  • Also on file: Xylitol is rated "Insufficient Reliable Evidence To Rate" for Cystic fibrosis, Hematopoietic stem cell transplant (HSCT), Coronavirus disease 2019 (COVID-19), Gulf war syndrome.

Xylitol is likely effective for preventing cavities (dental caries). For ear infections (otitis media), the evidence is weaker — it's possibly effective.

The data doesn't establish whether it helps with gulf war syndrome, cystic fibrosis, or dry mouth. Plant Sterols are likely effective for lowering cholesterol (hypercholesterolemia), including familial high cholesterol.

They're possibly effective for lowering the risk of heart disease. We don't have effectiveness data on file for Plant Sterolins.

The evidence, ingredient by ingredient Xylitol Plant Sterols

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 1 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Xylitol is generally well tolerated in the amounts found in food, though high doses (30–40 grams) can cause digestive upset — diarrhea, gas, and cramping. A few cases of allergic reactions have been reported, including one serious reaction in a very young child.

Minor stinging in the nose or occasional nosebleeds have been reported with nasal use. Plant Sterols are generally well tolerated at normal supplement doses for most adults.

Pregnancy and breastfeeding: the safety of concentrated plant sterol supplements hasn't been well studied, so talk with your doctor before using this product if you're pregnant or nursing. One case of a skin rash and one case of digestive upset have been reported.

Pregnancy and breastfeeding data for Plant Sterolins aren't on file.

Side effects, ingredient by ingredient Xylitol Plant Sterols

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Run your medications through the interaction checker below before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Moducare may be worth considering if you want to support cholesterol levels and dental health — Xylitol is likely effective for cavities and Plant Sterols for cholesterol. If you're pregnant, nursing, or take any medications, check with your pharmacist first.

Don't give this product to dogs, as xylitol is toxic to them.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Moducare, straight from the product label.

Brand Moducare
Barcode (UPC) 772570000512
Net contents 60 Vegetarian Grape Chewable Tablet(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 333114
Product type Fat/fatty Acid
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Moducare by Moducare, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
120
UPC/BARCODE
772570000512
IngredientAmount% DV
Total Carbohydrates1 Gram(s)1%
Sugar0 Gram(s)--
Xylitol1 Gram(s)--
Moducare0 NP--
Plant Sterols20 mg--
Plant Sterolins0.2 mg--

Other ingredients: Microcrystalline Cellulose, Grape flavor, Inulin, Silicon Dioxide, Citric Acid, Magnesium Stearate, Malic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Moducare is a patented blend of plant sterols and sterolins in a clinically proven ratio of 100:1 that works to restore, strengthen and balance your body's immune system. U.S. Patent No. 5,486,510

Suggested/Recommended/Usage/Directions

Take Moducare grape chewables daily and adopt healthy lifestyle habits so you and your family can keep your immune system strong and enjoy vibrant health.

Suggested use: Chew one tablet 3 times daily between meals.

Brand IP Statement(s)

U.S. Patent No. 5,486,510 Moducare is a registered trademark of Essential Sterolin Products (PTY) Ltd.

Precautions

Do not use if outer band or inner safety seal is broken or missing.

Caution: If you are pregnant, nursing, a diabetic, an organ transplant recipient or have multiple sclerosis, do not use unless on advice of and under direct supervision of a healthcare professional.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

GMP Certified

Formulation

Daily Immune support Restores Strengthens Balances

Free of: GMOs, soy, gluten, dairy.

Suitable for vegetarians.

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry place with lid tightly closed.

See for yourself

Moducare by Moducare label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Moducare by Moducare

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

0 Gram(s) per serving

Xylitol

No known
interactions
1 Gram(s) per serving

Xylitol is a sugar alcohol used as a low-calorie sweetener that has the best-supported benefit for reducing cavities, especially in chewing gum or loz...

Xylitol monograph & interactions

Moducare

0 NP per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Grape flavor, Inulin, Silicon Dioxide, Citric Acid, Magnesium Stearate, Malic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Moducare by Moducare Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Moducare. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Moducare, from the product label.

Moducare

See all Moducare products
Name
Wakunaga of America Co., Ltd.
City
Mission Viejo
State
CA
ZipCode
92691
Phone Number
800-421-2998
Web Address
www.kyolic.com
Pharmacist Counseling Corner

Moducare by Moducare: Common Questions

Does Moducare by Moducare interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Moducare. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Moducare contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will Moducare cause digestive problems?
Xylitol at high doses (30–40 grams) can cause gas, diarrhea, and cramping. The doses in this product shouldn't reach that level, but if you're sensitive, you might notice some mild discomfort. Start with a lower dose and see how you feel.
Is this safe if I'm pregnant or breastfeeding?
The safety of concentrated plant sterol supplements during pregnancy and breastfeeding hasn't been well studied. Talk with your doctor or pharmacist before using Moducare if you're pregnant or nursing — they can advise you based on your situation.
Can I give this to my dog?
No. Xylitol, one of the active ingredients in Moducare, is highly toxic to dogs. Keep it out of reach of pets entirely.
How does this help cholesterol?
Plant Sterols work by blocking some of the cholesterol your gut absorbs from food. Over time, this can help lower your blood cholesterol levels, which may reduce your heart disease risk.
Does Moducare really prevent cavities?
Xylitol — the first ingredient — is likely effective for preventing cavities when used regularly. It works by changing the environment in your mouth that bacteria need to survive and cause decay.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Moducare is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Moducare label
Sources

Sources & How We Checked

Moducare's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Xylitol 7 references
  1. Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.
  2. Weissman JD, Fernandez F, Hwang PH. Xylitol nasal irrigation in the management of chronic rhinosinusitis: a pilot study. Laryngoscope 2011;121:2468-72. PubMed
  3. Okamoto K, Kagami M, Kawai M, et al. Anaphylaxis to xylitol diagnosed by skin prick test and basophil activation test. Allergol Int. 2019;68(1):130-131. PubMed
  4. Rabago D, Kille T, Mundt M, Obasi C. Results of a RCT assessing saline and xylitol nasal irrigation for CRS and fatigue in Gulf War illness. Laryngoscope Investig Otolaryngol 2020;5(4):613-620.
  5. Wołyniec W, Szwarc A, Kasprowicz K, et al. Impact of hydration with beverages containing free sugars or xylitol on metabolic and acute kidney injury markers after physical exercise. Front Physiol 2022;13:841056. PubMed
  6. Bordier V, Teysseire F, Drewe J, et al. Effects of a 5-week intake of erythritol and xylitol on vascular function, abdominal fat and glucose tolerance in humans with obesity: a pilot trial. BMJ Nutr Prev Health 2023;6(2):264-272. PubMed
  7. Margulis I, Cohen-Kerem R, Stein N, et al. Xylitol nasal spray for prevention of recurrent acute otitis media in children: A prospective two-center cohort study. Int J Pediatr Otorhinolaryngol 2024;176:111818. PubMed

See these in context on the Xylitol monograph →

Plant Sterols 3 references
  1. Guardamagna, O., Abello, F., Baracco, V., Federici, G., Bertucci, P., Mozzi, A., Mannucci, L., Gnasso, A., and Cortese, C. Primary hyperlipidemias in children: effect of plant sterol supplementation on plasma lipids and markers of cholesterol synthesis a
  2. Haque Hussain SS, Weir J, Roberts N. Severe dermatitis secondary to plant sterol supplements. Clin Exp Dermatol. 2009 Oct;34(7):e276-7. PubMed
  3. Xue P, Wang Y, Chen Y, et al. A Case of Peripheral Precocious Puberty May Be Caused by a Diet Containing Phytosterols in a 20-Month-Old Boy. Horm Res Paediatr 2022;95(5):484-491. PubMed

See these in context on the Plant Sterols monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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