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Dietary supplement

Mullein Ingredients & Drug Interactions

by Nature's Sunshine

Mullein label
See full label image
Capsule Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Mullein against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Mullein is a dietary supplement by Nature's Sunshine with 1 active ingredient. Its ingredients are commonly taken for cough and chest congestion, sore throat, bronchitis and respiratory irritation.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Mullein. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Mullein by Nature's Sunshine

Ask about any prescription or over-the-counter medication and we check it for interactions with Mullein by Nature's Sunshine — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Mullein by Nature's Sunshine

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: mullein, a flowering plant traditionally used to support respiratory health. The capsule itself is an inactive ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Mullein's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: traditional respiratory support.
  • We looked for evidence on: Asthma, Bronchitis, Cough, Influenza, Pneumonia, sore throat — and 1 related terms.
  • The closest evidence on file: Mullein is rated "Insufficient Reliable Evidence To Rate" for Bronchitis (Natural Medicines).
  • Also on file: Mullein is rated "Insufficient Reliable Evidence To Rate" for Asthma, Cough, Influenza, Pneumonia.

The evidence for mullein isn't established in the data we hold. The product facts show insufficient reliable evidence to rate it for bronchitis, asthma, cough, migraine headache, or diarrhea — which means studies either haven't been done, are too small, or show mixed results.

If you're considering mullein for one of these uses, talk it over with your doctor or pharmacist about what the current science actually supports.

The evidence, ingredient by ingredient Mullein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mullein is generally well tolerated for short-term use, though human safety data are limited. A couple of case reports describe dermatitis (a skin rash) from direct skin contact with the whole plant or from breathing in plant dust — most often in people who also reacted to other plants.

During pregnancy, safety data aren't sufficient; the facts advise against it. The same goes for breastfeeding — there isn't enough information to know it's safe.

If you're pregnant or nursing, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Mullein

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Mullein.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before you start if you take any blood thinners (anticoagulants) or antiplatelet drugs like warfarin, aspirin, or clopidogrel — mullein extracts do show mild blood-thinning properties in the lab.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Mullein may interest you if you want to try a traditional respiratory herb, but know that evidence for its effectiveness isn't established and human safety data are thin. If you take any blood thinner or antiplatelet medication, check with your doctor or pharmacist first — mullein does have a mild blood-thinning effect.

Pregnant or breastfeeding? Skip it unless your doctor says otherwise.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mullein, straight from the product label.

Brand Nature's Sunshine
Barcode (UPC) 099904004603
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 278175
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mullein by Nature's Sunshine, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
UPC/BARCODE
099904004603
IngredientAmount% DV
Mullein580 mg--

Other ingredients: Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Bottle made from 100% post consumer recycled material. We are committed to you and our planet. Scan to learn more.

We source the world's purest ingredients, no matter where they are grown, to ensure the active nutrients are delivered just as nature intended.

New look! Same great product

Seals/Symbols

Ko Pareve (Kosher)

Formula

Ko Pareve (Kosher)

Precautions

Do not use if inner seal is missing or damaged.

Formulation

Traditional respiratory support

Guaranteed pure

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Natures Sunshine Herbal experts since 1972

Suggested/Recommended/Usage/Directions

Recommended Use: Take 2 capsules with a meal twice daily.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Mullein by Nature's Sunshine label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Mullein label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Mullein by Nature's Sunshine

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Mullein

Interacts with
122 drugs
580 mg per serving

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality huma...

Mullein monograph & interactions

Other (inactive) ingredients: Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mullein by Nature's Sunshine Drug Interactions

Want to check YOUR meds against Mullein?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Minor

Ingredients driving the most interactions

Mullein 122

Individual Drug Interactions

The ingredients in Mullein interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Mullein interact with drugs. Each result below shows which ingredient is responsible. Mullein

Each ingredient & the kinds of drugs it affects

For each ingredient in Mullein with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Mullein1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot. This is likely due to at least one of the known constituents of muellein, triterpenoid saponins. However, the effects appear to be mild and results have been inconsistent. Extracts from different plant parts have been show to have varying anticoagulant strengths, with water-based ones being more potent than alcohol-based extracts.

Likelihood Unlikely Evidence A
Mullein full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Mullein, from the product label.

Nature's Sunshine

See all Nature's Sunshine products
Name
Nature's Sunshine Products, Inc.
City
Spanish Fork
State
Utah
ZipCode
84660
Phone Number
1-800-223-8225
Web Address
www.naturessunshine.com
Pharmacist Counseling Corner

Mullein by Nature's Sunshine: Common Questions

Does Mullein by Nature's Sunshine interact with any medications?
Yes. Based on its ingredients, Mullein has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mullein contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take mullein if I'm pregnant?
No — the safety data advise against it during pregnancy. Talk with your doctor or pharmacist about whether mullein is right for you.
Is mullein safe while breastfeeding?
There isn't enough data to know either way. It's best to check with your doctor or pharmacist before taking it if you're nursing.
Does mullein actually work for cough or bronchitis?
The evidence isn't established in the data we hold — meaning studies are either missing, too small, or mixed. Your doctor can discuss whether mullein makes sense for your symptoms.
What is mullein and what's it used for?
Mullein is a flowering plant traditionally used to support respiratory health. People often try it for cough, bronchitis, and asthma, though evidence for those uses isn't solid.
Has mullein been reported to cause any side effects?
A couple of case reports describe dermatitis (skin rash) from direct skin contact with the plant or from breathing in plant dust, especially in people who also reacted to other plants. Short-term use is generally well tolerated, but long-term safety data are limited.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Mullein is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mullein label
Go deeper

The Full Monographs Behind Mullein’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Mullein

Interacts with 122 drugs

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality human studies are lacking, so its benefits a...

Read the full Mullein monograph →
Sources

Sources & How We Checked

Mullein's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mullein 2 references
  1. Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
  2. Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.

See these in context on the Mullein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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