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Dietary supplement

Mullein Leaf 500 mg Ingredients & Drug Interactions

by Nature's Answer

Mullein Leaf 500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Mullein Leaf 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Mullein Leaf 500 mg is a dietary supplement by Nature's Answer with 1 active ingredient. Its ingredients are commonly taken for cough and chest congestion, sore throat, bronchitis and respiratory irritation.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Mullein. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Mullein Leaf 500 mg by Nature's Answer

Ask about any prescription or over-the-counter medication and we check it for interactions with Mullein Leaf 500 mg by Nature's Answer — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Mullein Leaf 500 mg by Nature's Answer

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: mullein leaf at 500 mg per capsule. Mullein is a plant traditionally used for respiratory and other purposes.

The capsule itself is made from vegetable cellulose, with rice flour and calcium silicate as inactive ingredients to help with manufacturing and stability.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Mullein's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports healthy respiratory function.
  • We looked for evidence on: Asthma, Bronchitis, Cough, Influenza, Pneumonia, Chest congestion — and 2 related terms.
  • The closest evidence on file: Mullein is rated "Insufficient Reliable Evidence To Rate" for Bronchitis (Natural Medicines).
  • Also on file: Mullein is rated "Insufficient Reliable Evidence To Rate" for Asthma, Cough, Influenza, Pneumonia.

The evidence for mullein isn't established in our data. We have insufficient reliable evidence to rate it for bronchitis, asthma, cough, migraine headache, or diarrhea.

If you're thinking about it for one of these, that's a conversation to have with your doctor or pharmacist about whether the evidence and your situation match up.

The evidence, ingredient by ingredient Mullein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mullein is generally well tolerated for short-term use, though human safety data are limited. A small number of case reports describe dermatitis (skin irritation) after topical exposure to the whole plant or by breathing in plant dust occupationally — in one case the person also reacted to other plants.

The safety data advise against mullein during pregnancy and while breastfeeding because there isn't enough information to be confident it's safe in those situations. Talk with your doctor or pharmacist if you're pregnant, planning to be, or breastfeeding.

Side effects, ingredient by ingredient Mullein

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Mullein.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any anticoagulant or antiplatelet medication — blood thinners like warfarin, aspirin, clopidogrel, or others — check with your doctor or pharmacist before adding mullein, as it may mildly boost their blood-thinning effect.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Mullein Leaf is a single-ingredient supplement with limited human safety data and insufficient evidence for the conditions it's traditionally used for. If you take blood thinners or antiplatelet medications, check with your doctor or pharmacist before starting.

A conversation with your own healthcare provider about whether this fits your needs is the best first step.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 19, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mullein Leaf 500 mg, straight from the product label.

Brand Nature's Answer
Barcode (UPC) 083000162985
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD May 19, 2022
DSLD ID 264257
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mullein Leaf 500 mg by Nature's Answer, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
083000162985
IngredientAmount% DV
Mullein500 mg--

Other ingredients: Vegetable Cellulose, Rice Flour, Calcium Silicate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Discover Nature’s Answer and trust the Difference... The True Nature of Our Standards goes way beyond the herb…

Nature's Answer Since 1972

Nature's Answer Discover Nature's Answer

Copyright 2019 Nature's Answer

Precautions

Prop. 65 Warning for California Residents Warning: Consuming this product can expose you to chemicals including lead, which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food.

Warning: Keep out of reach of children.

Do not use if safety seal is damaged or missing.

If you are pregnant, nursing, taking any medications, planning any medical procedure or have a medical condition, consult with your healthcare practitioner before use.

Storage

Store in a cool, dry place.

Formula

K Parve (Kosher)

Verbascum thapsus

Seals/Symbols

K Parve (Kosher)

Formulation

Supports Healthy Respiratory Function

Vegan

Gluten-Free

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one (1) capsule 1-3 times a day with food or water.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

For product information, call (800) 439-2324.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Mullein Leaf 500 mg by Nature's Answer label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Mullein Leaf 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Mullein Leaf 500 mg by Nature's Answer

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Mullein

Interacts with
122 drugs
500 mg per serving

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality huma...

Mullein monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Rice Flour, Calcium Silicate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mullein Leaf 500 mg by Nature's Answer Drug Interactions

Want to check YOUR meds against Mullein Leaf 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Minor

Ingredients driving the most interactions

Mullein 122

Individual Drug Interactions

The ingredients in Mullein Leaf 500 mg interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Mullein Leaf 500 mg interact with drugs. Each result below shows which ingredient is responsible. Mullein

Each ingredient & the kinds of drugs it affects

For each ingredient in Mullein Leaf 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Mullein1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot. This is likely due to at least one of the known constituents of muellein, triterpenoid saponins. However, the effects appear to be mild and results have been inconsistent. Extracts from different plant parts have been show to have varying anticoagulant strengths, with water-based ones being more potent than alcohol-based extracts.

Likelihood Unlikely Evidence A
Mullein full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Mullein Leaf 500 mg, from the product label.

Nature's Answer

See all Nature's Answer products
Name
Nature's Answer
Street Address
85 Commerce Drive
City
Hauppauge
State
NY
ZipCode
11788
Phone Number
(800) 439-2324
Web Address
www.naturesanswer.com
Pharmacist Counseling Corner

Mullein Leaf 500 mg by Nature's Answer: Common Questions

Does Mullein Leaf 500 mg by Nature's Answer interact with any medications?
Yes. Based on its ingredients, Mullein Leaf 500 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mullein Leaf 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take mullein if I'm pregnant or breastfeeding?
The safety data advise against it during both pregnancy and breastfeeding because there isn't enough information to know either way. Talk with your doctor or pharmacist for personalized guidance on your situation.
What is mullein used for?
Mullein is traditionally used for respiratory issues like bronchitis and cough, as well as migraine headache and diarrhea. However, we don't have reliable evidence showing it actually works for these — that's why the evidence is rated insufficient.
Does mullein have any side effects?
It's generally well tolerated for short-term use, though human safety data are limited. A small number of case reports mention dermatitis (skin irritation) after skin contact with the whole plant or breathing in plant dust, particularly in occupational settings.
I'm on a blood thinner — is this product safe for me?
Mullein has mild blood-thinning effects of its own, so it could add to what your medication is doing. Check with your doctor or pharmacist before you start to make sure the combination is right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Mullein Leaf 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mullein Leaf 500 mg label
Go deeper

The Full Monographs Behind Mullein Leaf 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Mullein

Interacts with 122 drugs

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality human studies are lacking, so its benefits a...

Read the full Mullein monograph →
Sources

Sources & How We Checked

Mullein Leaf 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mullein 2 references
  1. Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
  2. Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.

See these in context on the Mullein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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