Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Multi-Care Night Natural Berry Flavor Ingredients & Drug Interactions

by Vicks

Multi-Care Night Natural Berry Flavor label
See full label image
Liquid Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Multi-Care Night Natural Berry Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Multi-Care Night Natural Berry Flavor is a dietary supplement by Vicks with 5 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 2,189 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marshmallow (Althaea officinalis L.) root extract, Chamomile (Matricaria recutita L.) flower extract, English Ivy (Hedera helix L.) leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Multi-Care Night Natural Berry Flavor by Vicks

Ask about any prescription or over-the-counter medication and we check it for interactions with Multi-Care Night Natural Berry Flavor by Vicks — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Multi-Care Night Natural Berry Flavor by Vicks

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 5 active ingredients.
  • “Multi-Care Night Botanical Blend” is a proprietary blend — the label gives one combined amount (482 mg) without saying how much of each component you get.

Multi-Care Night contains five active ingredients. Sodium supports essential body functions but is present as a concern when combined with certain drugs.

Elderberry, chamomile (German chamomile flower extract), English ivy leaf extract, and marshmallow root extract are all plant-based ingredients traditionally used to support nighttime comfort and wellness. The product also includes inactive ingredients such as water, sucrose, glycerin, and less than 2% of other materials that serve as the liquid base and preservatives.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Soothes cough and clears mucus.
  • We looked for evidence on: Cough, Lower respiratory tract infections, Upper respiratory tract infection (URTI), Respiratory tract infections, Bronchitis, Common cold — and 4 related terms.
  • The closest evidence on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).
  • Also on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Rhinosinusitis, Upper respiratory tract infection (URTI), Lower respiratory tract infections.
  • Also on file: English Ivy is rated "Insufficient Reliable Evidence To Rate" for Bronchitis, Respiratory tract infections, Cough.

The evidence supporting these ingredients is limited. For sodium, there's possibly effective evidence for amphotericin B kidney damage and likely effective evidence for cystic fibrosis support, though that's not what this product is marketed for.

For elderberry, chamomile, English ivy, and marshmallow, the data we hold shows insufficient reliable evidence to rate their effectiveness for allergies, respiratory infections, cognitive function, anxiety, or the other conditions studied. This doesn't mean they don't work — it means the evidence isn't established in our current data.

The evidence, ingredient by ingredient Sodium Elderberry German Chamomile English Ivy Marshmallow

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sodium is well tolerated in normal dietary amounts, but high intake is linked to high blood pressure and heart strain — avoid supplements or excess without medical advice. Chamomile is generally well tolerated but can cause allergic reactions in people sensitive to ragweed and related plants.

Elderberry prepared from ripe fruit is well tolerated; raw or unripe berries and plant parts contain cyanogenic glycosides that can cause nausea, vomiting, severe diarrhea, weakness, dizziness, and numbness (cooking eliminates the toxin). English ivy leaf extract is generally well tolerated, though the raw plant is toxic.

Marshmallow is generally well tolerated for short-term use, but human safety data are limited. For pregnancy: the safety data advise against sodium supplements and elderberry during pregnancy.

For chamomile, there isn't enough reliable safety information, so it is best avoided during pregnancy unless your doctor approves. For English ivy and marshmallow, there isn't enough data to know either way — talk with your doctor or pharmacist for personalized advice.

For breastfeeding: the data advise against elderberry and English ivy. For chamomile and marshmallow, limited or insufficient data exist — check with your doctor or pharmacist before use.

Side effects, ingredient by ingredient Sodium Elderberry German Chamomile English Ivy Marshmallow

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Elderberry, English Ivy, Marshmallow, German Chamomile, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; lithium.
  • For scale: 2,190 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check if you're on blood pressure medications, corticosteroids, lithium, didanosine, tolvaptan, sodium phosphate products, or any other sodium-containing drugs — sodium can affect how they work or raise your sodium dangerously. If you take sedating drugs (sleep aids, antihistamines), anti-clotting medications like warfarin, birth control pills, hormone replacement, the cancer drug pazopanib, or drugs broken down by your liver through the CYP2D6, CYP2C9, CYP3A4, CYP2C19, or CYP2C8 pathways, mention this product to your pharmacist before you use it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product brings together multiple plant ingredients, but the main concern is sodium, especially if you're on blood pressure meds, steroids, lithium, or certain other drugs. Chamomile and the other botanicals add theoretical interactions with liver enzymes and other medications.

If you take any prescription, run it through the checker on this page before adding this supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Multi-Care Night Natural Berry Flavor, straight from the product label.

Brand Vicks
Barcode (UPC) 323900041073
Net contents 4 fl. Oz.; 118 mL
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 247868
Product type Botanical With Nutrients
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Gluten Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Multi-Care Night Natural Berry Flavor by Vicks, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 mL, 10 mL
Maximum serving Sizes:
5 mL, 10 mL
Servings per container
11
UPC/BARCODE
323900041073
IngredientAmount% DV
Calories15 Calorie(s), 10 Calorie(s)--
Total Carbohydrates3 Gram(s), 2 Gram(s)1%
Sodium10 mg, 5 mg1%, 1%
Added Sugars2 Gram(s), 1 Gram(s)5%, 5%
Total Sugars3 Gram(s), 2 Gram(s)--
Elderberry0 NP, 0 NP--
Chamomile (Matricaria recutita L.) flower extract0 NP--
English Ivy (Hedera helix L.) leaf extract0 NP, 0 NP--
Marshmallow (Althaea officinalis L.) root extract0 NP, 0 NP--
Multi-Care Night Botanical Blend482 mg, 241 mg--

Other ingredients: Water, Sucrose, Glycerin, Less than 2% of

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Paper box Discard seal, empty & replace cap Check locally Plastic bottle how2recycle.info Not recycled in all communities

From the makers of Vicks

2 Bottles - 4 fl oz (118 mL) each; Total 8 fl oz (236 mL) Servings per container: about 23 about 11

www.pg.com www.vicks.com Patents: www.pg.com/patents

Over 125 years ago, Vicks was created by a pharmacist father comforting his son, using only the best botanical ingredients from around the world.

Vicks - Trusted by parents since 1894.

Questions? 1-800-362-1683

Formulation

Drug free

Made in Canada

No drugs No artificial dyes No high fructose corn syrup No honey No gluten

Formula

Soothes cough Marshmallow root Helps clear mucus Ivy leaf Soothes nasal irritation Elderberry + Chamomile

Today, Children's Botanicals from Vicks carries on that legacy providing multi-care support for your children with natural ingredients like Elderberry, Marshmallow Root, and English Ivy Leaf.

Ages 1+

FDA Statement of Identity

Dietary Supplement

Precautions

Warnings: Do not use for more than 7 days, or if symptoms persist or worsen during use.

Do not use if your child is allergic to English ivy, chamomile, or any of the other ingredients in the product.

Avoid taking the product simultaneously with drugs, as marshmallow root may slow the absorption. Do not use with drugs or herbal supplements unless directed by your healthcare provider. Consult a physician if cough persists or before using if you are pregnant or nursing.

Keep out of reach of children.

This product is not intended to treat cold/flu.

Storage

Store at no greater than 25 degrees C. Do not freeze. Do not refrigerate.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions: Shake well before use. Suggested serving (take up to 3 times per day) Children 1 - 3 years 5 mL Children 4 years & over 10 mL When using a combination of Children's Botanicals Multi-Care products, do not exceed a total of 3 servings in 24 hours.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Multi-Care Night Natural Berry Flavor by Vicks label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Multi-Care Night Natural Berry Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Multi-Care Night Natural Berry Flavor by Vicks

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 mL Dosage formLiquid Servings per container11 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sodium

Interacts with
205 drugs
10 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Other (inactive) ingredients: Water, Sucrose, Glycerin, Less than 2% of. These complete the product’s ingredient list but are not active constituents.

Interaction report

Multi-Care Night Natural Berry Flavor by Vicks Drug Interactions

Want to check YOUR meds against Multi-Care Night Natural Berry Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,189Drugs
1,162 Moderate 1,027 Minor

Ingredients driving the most interactions

Marshmallow (Althaea officinalis L.) root extract 2,040
Chamomile (Matricaria recutita L.) flower extract 960
English Ivy (Hedera helix L.) leaf extract 280
Sodium 205
Elderberry 121

Individual Drug Interactions

The ingredients in Multi-Care Night Natural Berry Flavor interact with 2,189 drugs. Click any drug to see the details.

5 of the 5 ingredients in Multi-Care Night Natural Berry Flavor interact with drugs. Each result below shows which ingredient is responsible. Marshmallow (Althaea officinalis L.) root extract Chamomile (Matricaria recutita L.) flower extract English Ivy (Hedera helix L.) leaf extract Sodium Elderberry

Each ingredient & the kinds of drugs it affects

For each ingredient in Multi-Care Night Natural Berry Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Marshmallow (Althaea officinalis L.) root extract3 drug types · 2,040 drugs

Lithium

Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.

Likelihood Possible Evidence D
Marshmallow (Althaea officinalis L.) root extract full monograph & interactions

Chamomile (Matricaria recutita L.) flower extract9 drug types · 960 drugs

Cns Depressants

Theoretically, German chamomile might have additive effects when used with CNS depressants.
German chamomile has mild sedative effects. Theoretically, concomitant use with drugs with sedative properties can cause additive effects and side effects.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, large amounts of German chamomile might reduce the effectiveness of oral contraceptives.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, concomitant use of large amounts of German chamomile might interfere with contraceptive drugs through competition for estrogen receptors.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, German chamomile might inhibit CYP2C9 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2C9. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2C9 in patients taking German chamomile.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2D6. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2D6 in patients taking German chamomile.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP3A4. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP3A4 in patients taking German chamomile.

Likelihood Possible Evidence D
Estrogens

Theoretically, large amounts of German chamomile might reduce the effectiveness of estrogens.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, large amounts of German chamomile might interfere with hormone replacement therapy through competition for estrogen receptors.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, large amounts of German chamomile might interfere with the activity of tamoxifen.
In vitro, German chamomile has demonstrated antiestrogenic activity.

Likelihood Possible Evidence D
Warfarin (Coumadin)

German chamomile might increase the effects of warfarin and increase the risk of bleeding.
In one case, a 70-year-old female taking warfarin developed retroperitoneal hematoma and bilateral recti muscle bleeding along with an INR of 7.9 following ingestion of German chamomile tea 4-5 cups daily and use of a topical chamomile-based lotion applied 4-5 times daily.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
In vitro and animal research shows that German chamomile might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP1A2 in patients taking German chamomile.

Likelihood Possible Evidence D
Chamomile (Matricaria recutita L.) flower extract full monograph & interactions

English Ivy (Hedera helix L.) leaf extract3 drug types · 280 drugs

Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, English ivy might increase the levels of drugs metabolized by CYP2C19.
In vitro research shows that English ivy inhibits CYP2C19 enzymes. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C8 (Cyp2C8) Substrates

Theoretically, English ivy might increase the levels of drugs metabolized by CYP2C8.
In vitro research shows that English ivy inhibits CYP2C8 enzymes. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, English ivy might increase the levels of drugs metabolized by CYP2D6.
In vitro research shows that English ivy inhibits CYP2D6 enzymes. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
English Ivy (Hedera helix L.) leaf extract full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Elderberry2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
Elderberry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Multi-Care Night Natural Berry Flavor, from the product label.

Vicks

See all Vicks products
Name
Procter & Gamble
City
Cincinnati
State
OH
ZipCode
45202
Phone Number
1-800-362-1683
Web Address
www.Vicks.com
Pharmacist Counseling Corner

Multi-Care Night Natural Berry Flavor by Vicks: Common Questions

Does Multi-Care Night Natural Berry Flavor by Vicks interact with any medications?
Yes. Based on its ingredients, Multi-Care Night Natural Berry Flavor has a known interaction with 2,189 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Multi-Care Night Natural Berry Flavor contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take this if I'm pregnant or breastfeeding?
Sodium and elderberry should not be used during pregnancy. For chamomile, there isn't enough safety data — talk with your doctor. For English ivy and marshmallow, there's no data on file for either pregnancy or breastfeeding — discuss with your healthcare provider. During breastfeeding, avoid elderberry and English ivy; for chamomile and marshmallow, the data are limited, so check with your pharmacist first.
What's in this product?
It has five active ingredients: sodium, elderberry, chamomile flower extract, English ivy leaf extract, and marshmallow root extract, plus water, sucrose, glycerin, and less than 2% of other inactive ingredients.
Can I take this if I'm on lithium?
No — sodium can raise lithium to toxic levels, and marshmallow may do the same because of possible diuretic effects. Talk to your doctor about alternatives.
Will this thin my blood?
Marshmallow flower theoretically has mild blood-thinning effects, though the root and leaf (which are what's in most supplements) are less of a concern. If you're already on warfarin or another blood thinner, mention this product to your pharmacist — chamomile can also increase warfarin's effects and bleeding risk.
Can I take this at the same time as my other medications?
Marshmallow's mucilage can interfere with how your body absorbs other oral drugs, so take it 30 to 60 minutes after your medications. For all other potential interactions, use the drug checker on this page with your exact prescriptions.
What are the most common side effects?
Elderberry prepared from ripe fruit is well tolerated. English ivy and marshmallow are generally well tolerated with limited side-effect data. Chamomile is well tolerated but can trigger allergic reactions in people sensitive to ragweed. Raw elderberry, English ivy leaves, and high sodium intake carry more serious risks — read the safety section above.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Multi-Care Night Natural Berry Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Multi-Care Night Natural Berry Flavor label
Go deeper

The Full Monographs Behind Multi-Care Night Natural Berry Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Elderberry

Interacts with 121 drugs

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu symptoms, but the evidence is limited and n...

Read the full Elderberry monograph → Herb & supplement monograph

German Chamomile

Interacts with 960 drugs

German chamomile is a widely used herbal remedy taken mainly as a tea for calming, sleep, and digestive complaints. Early research suggests possible benefits for mild anxiety and some skin o...

Read the full German Chamomile monograph → Herb & supplement monograph

English Ivy

Interacts with 280 drugs

English ivy leaf extract is most commonly used in cough and cold syrups to help loosen mucus and ease coughing, and it is a popular ingredient in many European herbal products. Some research...

Read the full English Ivy monograph → Herb & supplement monograph

Marshmallow

Interacts with 2,040 drugs

Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...

Read the full Marshmallow monograph →
Sources

Sources & How We Checked

Multi-Care Night Natural Berry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 77 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
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See these in context on the Sodium monograph →

Elderberry 6 references
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See these in context on the Elderberry monograph →

German Chamomile 15 references
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See these in context on the German Chamomile monograph →

English Ivy 13 references
  1. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
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  13. Kruttschnitt E, Wegener T, Zahner C, Henzen-Bücking S. Assessment of the Efficacy and Safety of Ivy Leaf (Hedera helix) Cough Syrup Compared with Acetylcysteine in Adults and Children with Acute Bronchitis. Evid Based Complement Alternat Med. 2020 May 4;2

See these in context on the English Ivy monograph →

Marshmallow 5 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
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See these in context on the Marshmallow monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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