Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Multi Collagen Protein 2250 mg Ingredients & Drug Interactions

by Nutrivein

Multi Collagen Protein 2250 mg label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Multi Collagen Protein 2250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Multi Collagen Protein 2250 mg is a dietary supplement by Nutrivein with 6 active ingredients. Its ingredients are commonly taken for skin health and wrinkles, joint pain and osteoarthritis, bone health.Based on those ingredients, 1,430 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Ashwagandha, organic Amla berry extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Multi Collagen Protein 2250 mg by Nutrivein

Ask about any prescription or over-the-counter medication and we check it for interactions with Multi Collagen Protein 2250 mg by Nutrivein — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Multi Collagen Protein 2250 mg by Nutrivein

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Multi Collagen Protein Complex” is a proprietary blend — the label gives one combined amount (2,250 mg) without saying how much of each component you get.

This capsule contains six active ingredients: hydrolyzed bovine collagen peptides, eggshell membrane collagen, chicken bone broth collagen concentrate, organic amla berry extract (also called Indian gooseberry), hydrolyzed fish collagen peptides, and organic ashwagandha. The three collagen sources — from bovine, eggshell, and fish — provide protein building blocks for skin, joints, and connective tissue.

Indian gooseberry and ashwagandha are herbal extracts traditionally used for inflammation and stress. The capsule itself is made from vegetable cellulose.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Joint and connective tissue support.
  • We looked for evidence on: Joint pain, Osteoarthritis, Exercise-induced muscle damage, Exercise-induced muscle soreness, Tendinopathy, Sprains — and 3 related terms.
  • The strongest evidence on file: Eggshell Membrane is rated "Possibly Effective" for Osteoarthritis (Natural Medicines).
  • Also on file: Indian Gooseberry is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis.
  • Also on file: Ashwagandha is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis.

The collagen peptides (both bovine and fish varieties) are possibly effective for aging skin and dry skin, though evidence for muscle strength is mixed — studies suggest they may actually be ineffective for building muscle. For acne and athletic performance, the evidence isn't established.

Eggshell membrane collagen is possibly effective for osteoarthritis, but reliable evidence for aging skin, muscle strength, or general joint pain is lacking. Indian gooseberry shows possibly effective evidence for acid reflux (GERD) and high cholesterol, though the cholesterol evidence is classified as insufficient.

Ashwagandha is possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder, but evidence for bipolar disorder is not established.

The evidence, ingredient by ingredient Collagen Peptides Eggshell Membrane Indian Gooseberry Ashwagandha

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The collagen peptides are generally well tolerated, though nausea, indigestion, diarrhea, and gas can occur — these side effects are rare. Eggshell membrane is also generally well tolerated short-term, but anyone with an egg allergy must avoid it.

Indian gooseberry is well tolerated as a food but is less studied as a supplement; a small number of trial participants reported indigestion, fatigue, or muscle pain. Ashwagandha is generally well tolerated short-term in healthy adults, though drowsiness, diarrhea, nausea, and vomiting can happen — these are uncommon at typical doses.

Rare but serious concerns include ashwagandha's link to liver damage and one case report of intracranial bleeding. Pregnancy safety is a concern: bovine and fish collagen peptides are not well studied, so check with your doctor; eggshell membrane and ashwagandha should be avoided in pregnancy, and Indian gooseberry has not enough safety data in pregnancy.

For breastfeeding, bovine and fish collagen peptides have little data, eggshell membrane and ashwagandha should be avoided, and Indian gooseberry lacks reliable safety information.

Side effects, ingredient by ingredient Collagen Peptides Eggshell Membrane Indian Gooseberry Ashwagandha

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 4 matched ingredients can interact with medications — Indian Gooseberry, Ashwagandha.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,431 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take hepatotoxic drugs (medications known to stress the liver), antidiabetes drugs, anticoagulants or blood thinners, aspirin, clopidogrel (Plavix), antihypertensive drugs (blood pressure medications), CNS depressants (sedatives, sleeping pills, alcohol), benzodiazepines, thyroid hormones, immunosuppressants, or any drugs processed through CYP1A2 liver enzymes. Altogether, these interactions span 1,431 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product might appeal to someone looking to support skin health and manage stress with herbal and collagen support. If you take blood thinners, diabetes medications, blood pressure drugs, sedatives, benzodiazepines, thyroid hormones, immunosuppressants, or any liver-stressing medication, you'll need to check with your own doctor or pharmacist before starting — the interactions here are real and dose-dependent.

Pregnant or breastfeeding people should talk with their healthcare provider, as several ingredients lack safety data or should be avoided entirely. Use the search tool on this page to check your specific medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Multi Collagen Protein 2250 mg, straight from the product label.

Brand Nutrivein
Barcode (UPC) B07S5YX1YL
Net contents 180 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 243533
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Multi Collagen Protein 2250 mg by Nutrivein, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Vegetable Capsule(s)
Maximum serving Sizes:
3 Vegetable Capsule(s)
Servings per container
60
UPC/BARCODE
B07S5YX1YL
IngredientAmount% DV
hydrolyzed Bovine Collagen Peptides0 NP--
Multi Collagen Protein Complex2250 mg--
Eggshell Membrane Collagen0 NP--
Chicken Bone Broth Collagen concentrate0 NP--
organic Amla berry extract0 NP--
hydrolyzed Fish Collagen Peptides0 NP--
organic Ashwagandha0 NP--

Other ingredients: Vegetable Cellulose Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take three (3) veggie capsules once daily, preferably with a meal and water, or as directed by a healthcare professional.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Made on equipment that also process milk, fish tree nuts and soy.

Contains: Egg, fish

Storage

Store in a cool, dry place.

Storage: Keep tightly closed in a dry place and do not expose to excessive heat.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Made in USA GMP Good Manufacturing Practice Made in an FDA Registered Facility

Formulation

Third party tested

Vegan

Made with non-GMO ingredients

Promotes healthy skin and hair Helps build stronger nails Supports healthy teeth and gums

Zero: GMOs, fillers, preservatives, stearates, artificial ingredients, binders, dioxides, lactose Does Not Contain: Milk, tree nuts, wheat, peanuts, soy.

Formula

Multi Collagen Protein Type I, II, III, V and X 2250 mg per serving

FDA Statement of Identity

All Natural Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Multi Collagen Protein 2250 mg by Nutrivein label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Multi Collagen Protein 2250 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Multi Collagen Protein 2250 mg by Nutrivein

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Vegetable Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Multi Collagen Protein Complex

2250 mg per serving

Other (inactive) ingredients: Vegetable Cellulose Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Multi Collagen Protein 2250 mg by Nutrivein Drug Interactions

Want to check YOUR meds against Multi Collagen Protein 2250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,430Drugs
1,002 Moderate 428 Minor

Ingredients driving the most interactions

organic Ashwagandha 1,372
organic Amla berry extract 208

Individual Drug Interactions

The ingredients in Multi Collagen Protein 2250 mg interact with 1,430 drugs. Click any drug to see the details.

2 of the 6 ingredients in Multi Collagen Protein 2250 mg interact with drugs. Each result below shows which ingredient is responsible. organic Ashwagandha organic Amla berry extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Multi Collagen Protein 2250 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Ashwagandha10 drug types · 1,372 drugs

Antidiabetes Drugs

Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.

Likelihood Possible Evidence D
Thyroid Hormone

Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Serotonergic Drugs

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]

Likelihood Possible Evidence C
organic Ashwagandha full monograph & interactions

organic Amla berry extract4 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking Indian gooseberry 500 mg along with clopidogrel 75 mg or ecosprin 75 mg, as a single dose or for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg or ecosprin 75 mg alone. Until more is known, use caution when taking Indian gooseberry in combination with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking Indian gooseberry fruit or fruit extract alone or in conjunction with antidiabetes medications can lower blood glucose levels. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Aspirin

Theoretically, Indian gooseberry may increase the risk of bleeding if used with aspirin; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with ecosprin 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus ecosprin 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with ecosprin 75 mg alone.

Likelihood Possible Evidence B
Clopidogrel (Plavix)

Theoretically, Indian gooseberry may increase the risk of bleeding if used with clopidogrel; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with clopidogrel 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus clopidogrel 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg alone.

Likelihood Possible Evidence B
organic Amla berry extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Multi Collagen Protein 2250 mg, from the product label.

Nutrivein

See all Nutrivein products
Name
Nutrivein
Street Address
720 N 10th St. A-302
City
Renton
State
WA
ZipCode
98057
Phone Number
888-705-3526
Web Address
www.nutrivein.com
Pharmacist Counseling Corner

Multi Collagen Protein 2250 mg by Nutrivein: Common Questions

Does Multi Collagen Protein 2250 mg by Nutrivein interact with any medications?
Yes. Based on its ingredients, Multi Collagen Protein 2250 mg has a known interaction with 1,430 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Multi Collagen Protein 2250 mg contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe if I have an egg allergy?
No — the product contains eggshell membrane collagen, so if you have an egg allergy you must avoid it. Check the label and talk with your pharmacist to be sure.
Can I take this if I'm pregnant or breastfeeding?
The safety data is limited or unfavorable. Bovine and fish collagen are not well studied in pregnancy and breastfeeding; eggshell membrane and ashwagandha should be avoided in both. Indian gooseberry lacks enough safety information in either. Talk with your doctor or pharmacist about whether it's right for you.
Will this help my skin?
The collagen peptides (bovine and fish) are possibly effective for aging skin and dry skin based on clinical evidence. Eggshell membrane's effect on skin is not well established. Results vary from person to person.
Does this help with anxiety or sleep?
Ashwagandha in this product is possibly effective for anxiety, stress, and insomnia according to the evidence we hold. It's not a substitute for medical treatment, but it may be worth discussing with your doctor.
What side effects might I experience?
The collagen peptides can rarely cause nausea, indigestion, diarrhea, or gas. Ashwagandha may cause drowsiness, diarrhea, or nausea (uncommon at typical doses). Indian gooseberry can cause indigestion. Most people tolerate it well, but if you notice any unusual symptoms, stop and talk with your pharmacist.
Is there anything in this I should be concerned about?
Ashwagandha has been linked in rare cases to liver problems, so if you have liver disease or take medications that stress the liver, check with your doctor first. Indian gooseberry may increase bleeding risk if you're on blood thinners or aspirin. Use the medication checker on this page to verify your prescriptions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Multi Collagen Protein 2250 mg label
Go deeper

The Full Monographs Behind Multi Collagen Protein 2250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Collagen Peptides

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is still developing and results vary. They...

Read the full Collagen Peptides monograph → Herb & supplement monograph

Eggshell Membrane

Eggshell membrane is a natural source of collagen, hyaluronic acid, and other connective-tissue compounds that is marketed mainly for joint comfort and osteoarthritis. Some small studies sug...

Read the full Eggshell Membrane monograph → Herb & supplement monograph

Indian Gooseberry

Interacts with 208 drugs

Indian gooseberry (amla) is a vitamin C-rich fruit used in Ayurvedic medicine for many purposes, from antioxidant support to cholesterol and digestion. Early research is promising for some u...

Read the full Indian Gooseberry monograph → Herb & supplement monograph

Ashwagandha

Interacts with 1,372 drugs

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...

Read the full Ashwagandha monograph →
Sources

Sources & How We Checked

Multi Collagen Protein 2250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 43 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Collagen Peptides 2 references
  1. Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
  2. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed

See these in context on the Collagen Peptides monograph →

Eggshell Membrane 3 references
  1. Osteoarthritis — MedlinePlus (NIH) Source
  2. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  3. Using Dietary Supplements Wisely — NIH NCCIH Source

See these in context on the Eggshell Membrane monograph →

Indian Gooseberry 6 references
  1. Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
  2. Fatima N, Pingali U, Muralidhar N. Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus. Phytomedicine. 2014;21(5):579-85. PubMed
  3. Shanmugarajan D, Girish C, Harivenkatesh N, Chanaveerappa B, Prasanna Lakshmi NC. Antihypertensive and pleiotropic effects of Phyllanthus emblica extract as an add-on therapy in patients with essential hypertension-A randomized double-blind placebo-contro
  4. Akhtar MS, Ramzan A, Ali A, Ahmad M. Effect of amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients. Int J Food Sci Nutr. 2011;62(6):609-16.
  5. Usharani P, Fatima N, Muralidhar N. Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: a randomized, double-blind, controlled study. Diabetes Metab Syndr Obes. 20 PubMed
  6. Majeed M, Mundkur L, Paulose S, Nagabhushanam K. Novel Emblica officinalis extract containing ß-glucogallin vs. metformin: a randomized, open-label, comparative efficacy study in newly diagnosed type 2 diabetes mellitus patients with dyslipidemia. Food Fu

See these in context on the Indian Gooseberry monograph →

Ashwagandha 32 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Upton R, ed. Ashwagandha Root (Withania somnifera): Analytical, quality control, and therapuetic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia 2000:1-25.
  3. Davis L, Kuttan G. Effect of Withania somnifera on cyclophosphamide-induced urotoxicity. Cancer Lett 2000;148:9-17. PubMed
  4. Davis L, Kuttan G. Suppressive effect of cyclophosphamide-induced toxicity by Withania somnifera extract in mice. J Ethnopharmacol 1998;62:209-14. PubMed
  5. Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 2000;5:334-46. DOI
  6. Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root. Indian J Exp Biol 2000;38:607-9.
  7. Kulkarni RR, Patki PS, Jog VP, et al. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33:91-5. PubMed
  8. Ahumada F, Aspee F, Wikman G, Hancke J. Withania somnifera exract. Its effects on arterial blood pressure in anaesthetized dogs. Phytother Res 1991;5:111-14.
  9. Panda S, Kar A. Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice. J Ethnopharmacol 1999;67:233-39. PubMed
  10. Panda S, Kar A. Changes in thyroid hormone concentrations after administration of ashwagandha root extract to adult male mice. J Pharm Pharmacol 1998;50:1065-68. PubMed
  11. Sehgal, V. N., Verma, P., and Bhattacharya, S. N. Fixed-drug eruption caused by ashwagandha (Withania somnifera): a widely used Ayurvedic drug. Skinmed. 2012;10(1):48-49.
  12. Agnihotri AP, Sontakke SD, Thawani VR, Saoji A, Goswami VS. Effects of Withania somnifera in patients of schizophrenia: a randomized, double blind, placebo controlled pilot trial study. Indian J Pharmacol. 2013;45(4):417-8. PubMed
  13. Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KI. Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients. Integr Cancer Ther. 2013;12(4):312-22.
  14. Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed
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See these in context on the Ashwagandha monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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