Interactions on record — worth a quick check against your medications. Based on 1 of 8 ingredients. Check your meds →
Dietary supplement

Natura 701 Ingredients & Drug Interactions

by AN American Nutriceuticals

Natura 701 label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Natura 701 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Natura 701 is a dietary supplement by AN American Nutriceuticals with 8 active ingredients. Its ingredients are commonly taken for bladder and kidney complaints, digestive upset, skin irritation and chafing.Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Shen Jin Cao. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Natura 701 by AN American Nutriceuticals

Ask about any prescription or over-the-counter medication and we check it for interactions with Natura 701 by AN American Nutriceuticals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Natura 701 by AN American Nutriceuticals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 8 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (250 mg) without saying how much of each component you get.

Natura 701 contains 8 ingredients in a proprietary blend formula, so the exact dose of each is not disclosed on the label. One ingredient we can identify is Shen Jin Cao (clubmoss).

The other seven — Yan Hu, Huang Yao Zi, Ku Shen, Tou Gu Gao, Bu Gu Zhi, Xin Bu Gan, and Deng Zhan Hua — are traditional herbal names. The capsule is made with vegetable cellulose.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Clubmoss product and its label doesn't state a use — see Clubmoss's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for any of the ingredients in this product, so we cannot tell you whether it works for its stated purpose.

The evidence, ingredient by ingredient Clubmoss

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Clubmoss (Shen Jin Cao) carries serious safety concerns. It contains toxic alkaloids and has very limited safety data.

There's a documented risk of confusion with a related plant that caused cholinergic poisoning in two case reports — symptoms included sweating, nausea, dizziness, cramping, and slurred speech. Airborne exposure to clubmoss spores has been linked to asthma symptoms.

For pregnancy and breastfeeding, the safety data rates clubmoss as possibly unsafe, which means the data advises against use during these times. We hold no safety information for the other six ingredients in the blend.

Side effects, ingredient by ingredient Clubmoss

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Clubmoss.
  • The most serious interaction on file is rated Moderate.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications before taking this product if you use anticholinergic drugs (like atropine or benztropine), acetylcholinesterase inhibitors (like donepezil for Alzheimer's), or other cholinergic drugs (like bethanechol). All three drug types interact with clubmoss at Moderate severity, with a risk of reduced drug effect or added cholinergic side effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product contains ingredients with very limited safety data and one that carries real toxicity risks. If you're considering it, talk with your pharmacist or doctor first — especially if you take medications for memory, bladder function, or myasthenia gravis, or if you're pregnant or breastfeeding.

The ingredient and drug interaction checker on this page is a must-use before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Natura 701, straight from the product label.

Brand AN American Nutriceuticals
Barcode (UPC) 859658002375
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 219223
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Natura 701 by AN American Nutriceuticals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
859658002375
IngredientAmount% DV
Proprietary Blend250 mg--
Yan Hu0 NP--
Huang Yao Zi0 NP--
Ku Shen0 NP--
Tou Gu Gao0 NP--
Shen Jin Cao0 NP--
Bu Gu Zhi0 NP--
Xin Bu Gan0 NP--
Deng Zhan Hua0 NP--

Other ingredients: Vegetable Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 or more capsules daily on an empty stomach or as directed by your health care professional.

Precautions

Warning: Keep this food supplement out of children's reach.

Not intended for pregnant or nursing women.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Please recycle

Professional series

Formulation

(no) BPA

Clinical strength

GMO-free, vegan, vegetarian

GMO-free, vegan, vegetarian

FDA Statement of Identity

Herbal Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Natura 701 by AN American Nutriceuticals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Natura 701 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Natura 701 by AN American Nutriceuticals

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

250 mg per serving
  • › Yan Hu
  • › Huang Yao Zi
  • › Ku Shen
  • › Tou Gu Gao
  • › Shen Jin Cao
  • › Bu Gu Zhi
  • › Xin Bu Gan
  • › Deng Zhan Hua

Other (inactive) ingredients: Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Natura 701 by AN American Nutriceuticals Drug Interactions

Want to check YOUR meds against Natura 701?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
219Drugs
219 Moderate

Ingredients driving the most interactions

Shen Jin Cao 219

Individual Drug Interactions

The ingredients in Natura 701 interact with 219 drugs. Click any drug to see the details.

1 of the 8 ingredients in Natura 701 interact with drugs. Each result below shows which ingredient is responsible. Shen Jin Cao

Each ingredient & the kinds of drugs it affects

For each ingredient in Natura 701 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Shen Jin Cao3 drug types · 219 drugs

Acetylcholinesterase (Ache) Inhibitors

Evidence from in vitro research suggests that clubmoss extract can inhibit acetylcholinesterase activity. Theoretically, concurrent use of clubmoss with other acetylcholinesterase (AChE) inhibitors might have additive effects and increase the risk of cholinergic side effects. AChE inhibitors and cholinergic drugs include bethanechol (Urecholine), donepezil (Aricept), echothiophate (Phospholine Iodide), edrophonium (Enlon, Reversol, Tensilon), neostigmine (Prostigmin), physostigmine (Antilirium), pyridostigmine (Mestinon, Regonol), succinylcholine (Anectine, Quelicin), and tacrine (Cognex).

Likelihood Possible Evidence D
Anticholinergic Drugs

Evidence from in vitro research suggests that clubmoss extract can inhibit acetylcholinesterase activity. Theoretically, concurrent use of anticholinergic drugs and clubmoss might decrease the effectiveness of club moss or the anticholinergic agent. Some anticholinergic drugs include atropine, benztropine (Cogentin), biperiden (Akineton), procyclidine (Kemadrin), and trihexyphenidyl (Artane).

Likelihood Possible Evidence D
Cholinergic Drugs

Evidence from in vitro research suggests that clubmoss extract can inhibit acetylcholinesterase activity. Theoretically, concurrent use of clubmoss with other cholinergic drugs might have additive effects and increase the risk of cholinergic side effects. AChE inhibitors and cholinergic drugs include bethanechol (Urecholine), donepezil (Aricept), echothiophate (Phospholine Iodide), edrophonium (Enlon, Reversol, Tensilon), neostigmine (Prostigmin), physostigmine (Antilirium), pyridostigmine (Mestinon, Regonol), succinylcholine (Anectine, Quelicin), and tacrine (Cognex).

Likelihood Possible Evidence D
Shen Jin Cao full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Natura 701, from the product label.

AN American Nutriceuticals

See all AN American Nutriceuticals products
Name
American Nutriceuticals
City
Vancouver
State
WA
ZipCode
98682
Phone Number
888-848-2548
Web Address
www.888vitality.com
Pharmacist Counseling Corner

Natura 701 by AN American Nutriceuticals: Common Questions

Does Natura 701 by AN American Nutriceuticals interact with any medications?
Yes. Based on its ingredients, Natura 701 has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Natura 701 contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Shen Jin Cao?
Shen Jin Cao is the traditional Chinese name for clubmoss, an herb used in traditional medicine. It's included in this blend, but it carries safety concerns because it contains toxic alkaloids and has very limited safety testing.
Is this safe to take during pregnancy?
No. The safety data for clubmoss, the one ingredient we can evaluate, rates it as possibly unsafe during pregnancy. You should not take this product if you're pregnant or planning to become pregnant.
Is this safe while breastfeeding?
No. Clubmoss is rated as possibly unsafe during breastfeeding, so you should avoid this product if you're nursing.
Why is there a warning about confusing this with another plant?
Clubmoss is sometimes mixed up with a related plant called fir club moss, which contains huperzine A — a compound that is much stronger and caused serious poisoning in two documented cases. If a product is mislabeled or contaminated, the risk is real.
Can I use this if I take Alzheimer's medication?
You need to check with your pharmacist first. Clubmoss can interact with Alzheimer's drugs like donepezil (Aricept) at Moderate severity, and the combination could reduce how well your medication works or cause cholinergic side effects.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Natura 701 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Natura 701 label
Go deeper

The Full Monographs Behind Natura 701’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Clubmoss

Interacts with 219 drugs

Clubmoss (Lycopodium clavatum) is a primitive plant with a long history in folk medicine and homeopathy, but there is very little reliable human research to show it works for any health cond...

Read the full Clubmoss monograph →
Sources

Sources & How We Checked

Natura 701's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Clubmoss 3 references
  1. Felgenhauer N, Zilker T, Worek F, Eyer P. Intoxication with huperzine A, a potent anticholinesterase found in the fir club moss. J Toxicol Clin Toxicol 2000;38:803-8.. PubMed
  2. Orhan, I., Terzioglu, S., and Sener, B. Alpha-onocerin: an acetylcholinesterase inhibitor from Lycopodium clavatum. Planta Med. 2003;69(3):265-267.
  3. Cullinan, P., Cannon, J., Sheril, D., and Newman, Taylor A. Asthma following occupational exposure to Lycopodium clavatum in condom manufacturers. Thorax 1993;48(7):774-775. PubMed

See these in context on the Clubmoss monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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