Interactions on record — worth a quick check against your medications. Based on 5 of 10 ingredients. Check your meds →
Dietary supplement

Natura 801 Ingredients & Drug Interactions

by AN American Nutriceuticals

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Natura 801 is a dietary supplement by AN American Nutriceuticals with 10 active ingredients. Its ingredients are commonly taken for fluid retention and swelling, digestive complaints, sleep and calming support.Based on those ingredients, 2,086 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Che Qian Zi, Fu Ling, Bai Zhi. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Natura 801 by AN American Nutriceuticals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 10 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (250 mg) without saying how much of each component you get.

Natura 801 contains 10 ingredients, mostly traditional Chinese herbs. The active components include Panax notoginseng (San Qi), two forms of poria mushroom (Fu Ling and Zhu Ling), blond psyllium (Che Qian Zi), angelica root (Bai Zhi), and pagoda tree flower (Huai Mi).

Lu Xian Cao, Tu Fu Ling, Xuan Fu Hua, and Chuan Xiong round out the formula. The capsules themselves are made from vegetable cellulose.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Constipation — rated "Effective" (Blond Psyllium) (Natural Medicines).
  • On file: Coronary heart disease (CHD) — rated "Likely Effective" (Blond Psyllium) (Natural Medicines).
  • On file: Hyperlipidemia — rated "Likely Effective" (Blond Psyllium) (Natural Medicines).
  • On file: Angina — rated "Possibly Effective" (Panax Notoginseng) (Natural Medicines).
  • On file: Stroke — rated "Possibly Effective" (Panax Notoginseng) (Natural Medicines).

The evidence for most of these herbs is limited. Panax notoginseng shows possibly effective evidence for angina and stroke, though it is rated possibly ineffective for heart attack.

Blond psyllium is effective for constipation and likely effective for high cholesterol and coronary heart disease. The poria mushroom, pagoda tree, and angelica ingredients are rated insufficient evidence — meaning the data we hold doesn't establish whether they work for their traditional uses like fatigue, dementia, hemorrhoids, or menopausal symptoms.

If you're considering this product for a specific condition, talk it over with your doctor or pharmacist about whether the evidence supports its use for your situation.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these ingredients are generally well tolerated in traditional use, but human safety studies are limited. The most common side effects from Panax notoginseng are dry mouth, flushed skin, insomnia, nausea, nervousness, and rash.

Blond psyllium may cause abdominal pain, gas, constipation, or diarrhea, and rarely allergic reactions including swelling and anaphylaxis. Angelica can cause photosensitivity (sun sensitivity) and constipation.

Poria mushroom and pagoda tree have rarely caused allergic reactions. Pregnancy and breastfeeding: Panax notoginseng is rated likely unsafe in pregnancy and breastfeeding.

Angelica and pagoda tree should be avoided in pregnancy, and neither has enough safety data for breastfeeding. Poria mushroom is not recommended during pregnancy or breastfeeding.

Blond psyllium is rated likely safe in pregnancy but use only under your doctor's supervision. If you're pregnant, planning pregnancy, or breastfeeding, discuss this product with your doctor or pharmacist before use.

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Poria Mushroom, Pagoda Tree, Angelica Archangelica, Blond Psyllium, Panax Notoginseng.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications; lithium.
  • For scale: 2,087 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Natura 801, check with your doctor or pharmacist if you take blood thinners like warfarin (moderate risk of bleeding), heart or seizure medications (absorption concerns), diabetes drugs like metformin, mood stabilizers like lithium, or any antibiotic that increases sun sensitivity (doxycycline). Panax notoginseng and blond psyllium can also interact with caffeine metabolism and with sedatives.

No interactions are documented for Lu Xian Cao, Tu Fu Ling, Xuan Fu Hua, or Chuan Xiong, as we hold no data for those ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Natura 801 is a multi-herb blend with possible benefit for angina and stroke (via Panax notoginseng) and constipation or cholesterol (via blond psyllium), though most other traditional uses lack established evidence. Because it contains herbs that interact with blood thinners, seizure medications, diabetes drugs, mood stabilizers, and photosensitizing antibiotics—and because pregnancy safety is a concern for several ingredients—it's essential to check your medications with the tool on this page and discuss the product with your doctor or pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Natura 801, straight from the product label.

Brand AN American Nutriceuticals
Barcode (UPC) 859658002382
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 219224
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Natura 801 by AN American Nutriceuticals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
859658002382
IngredientAmount% DV
Proprietary Blend250 mg--
Lu Xian Cao0 NP--
Fu Ling0 NP--
Tu Fu Ling0 NP--
San Qi0 NP--
Huai Mi0 NP--
Zhu Ling0 NP--
Xuan Fu Hua0 NP--
Chuan Xiong0 NP--
Bai Zhi0 NP--
Che Qian Zi0 NP--

Other ingredients: Vegetable Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 or more capsules daily on an empty stomach or as directed by your health care professional.

Precautions

Warning: Keep this food supplement out of children's reach.

Not intended for pregnant or nursing women.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Please recycle

(no) BPA

Professional series

Formulation

Clinical strength

GMO-free, vegan, vegetarian

GMO-free, vegan, vegetarian

FDA Statement of Identity

Herbal Dietary Supplement

See for yourself

Natura 801 by AN American Nutriceuticals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Natura 801 by AN American Nutriceuticals

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

250 mg per serving

Other (inactive) ingredients: Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Natura 801 by AN American Nutriceuticals Drug Interactions

Want to check YOUR meds against Natura 801?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,086Drugs
776 Moderate 1,310 Minor

Ingredients driving the most interactions

Che Qian Zi 2,025
Fu Ling 417
Bai Zhi 335
San Qi 207
Huai Mi 29

Each ingredient & the kinds of drugs it affects

For each ingredient in Natura 801 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Che Qian Zi7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, blond psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Blond psyllium might reduce carbamazepine absorption and serum levels. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug.

Likelihood Probable Evidence D
Lithium

Theoretically, taking blond psyllium at the same time as lithium might reduce lithium absorption.
The fiber in blond psyllium might decrease the absorption of lithium. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, blond psyllium might increase the therapeutic and adverse effects of metformin.
Concurrent use of blond psyllium with metformin slows and increases metformin absorption. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking blond psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in blond psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was taken concomitantly with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking blond psyllium at the same time as digoxin might reduce digoxin absorption.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking blond psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. However, this is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Conversely, case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin.

Likelihood Possible Evidence B

Fu Ling3 drug types · 417 drugs

Anticholinergic Drugs

Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.

Likelihood Possible Evidence D

Bai Zhi1 drug type · 335 drugs

Photosensitizing Drugs

Angelica archangelica, whether ingested or applied to the skin, has the potential to induce photosensitivity reactions. It is advised that patients using Angelica archangelica in any form should avoid prolonged exposure to sunlight. When combined with photosensitizing drugs like doxycycline, there is an elevated risk of photosensitivity reactions. Patients should be cautioned to take appropriate sun protection measures and monitor for any signs of skin irritation or photosensitivity when using these substances concomitantly. (Source: https://pubmed.ncbi.nlm.nih.gov/10630112/)

Likelihood Possible Evidence C

San Qi4 drug types · 207 drugs

Aspirin

Theoretically, taking Panax notoginseng concomitantly with aspirin may increase the risk of adverse effects from both products.
Animal research shows that taking Panax notoginseng extract with aspirin increases blood levels of salicylic acid by approximately 50% and blood levels of Panax notoginseng by 75% to 196%. This effect may be due to increased absorption of both products.

Likelihood Possible Evidence D
Caffeine

Theoretically, taking Panax notoginseng may decrease the levels and clinical effects of caffeine.
Animal research shows that administering Panax notoginseng intravenously for 7 days before intraperitoneal injection of caffeine can decrease maximal blood levels of caffeine by 37%. This interaction is attributed to the ability of Panax notoginseng to increase the activity of cytochrome P450 1A2 (CYP1A2) enzymes.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Animal research shows that administering Panax notoginseng intravenously for 7 days before intraperitoneal injection of caffeine can decrease maximal blood levels of caffeine by 37%. This interaction was attributed to the ability of Panax notoginseng to increase the activity of CYP1A2.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, taking Panax notoginseng concomitantly with warfarin may increase the risk of bleeding.
Animal research shows that taking Panax notoginseng concomitantly with warfarin increases plasma warfarin levels, prothrombin time, and international normalized ratio when compared with control. In vitro research also suggests that Panax notoginseng may downregulate expression of cytochrome P450 3A4 enzymes, which may affect warfarin metabolism.

Likelihood Possible Evidence D

Huai Mi1 drug type · 29 drugs

Caffeine

Theoretically, pagoda tree might reduce the clearance of caffeine.
Pagoda tree contains genistein. Taking genistein 1 gram daily for 14 days seems to inhibit caffeine clearance and metabolism in healthy females. This effect has been attributed to inhibition of the cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if this effect occurs with the lower amounts of genistein found in pagoda tree.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Natura 801, from the product label.

AN American Nutriceuticals

See all AN American Nutriceuticals products
Name
American Nutriceuticals
City
Vancouver
State
WA
ZipCode
98682
Phone Number
888-848-2548
Web Address
www.888vitality.com
Pharmacist Counseling Corner

Natura 801 by AN American Nutriceuticals: Common Questions

Does Natura 801 by AN American Nutriceuticals interact with any medications?
Yes. Based on its ingredients, Natura 801 has a known interaction with 2,086 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Natura 801 contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Natura 801 if I'm pregnant or breastfeeding?
Panax notoginseng is rated likely unsafe in both pregnancy and breastfeeding. Angelica and pagoda tree should be avoided in pregnancy, and poria mushroom isn't recommended for either. Blond psyllium is rated likely safe in pregnancy, but only under your doctor's supervision. The safety of the other herbs during pregnancy or breastfeeding isn't established. You need to talk this over with your doctor or pharmacist for guidance on your specific situation.
What is Panax notoginseng in this product supposed to do?
Panax notoginseng (San Qi) has possibly effective evidence for angina and stroke. It's been used to support blood flow and circulation. That said, it comes with interaction risks — especially with blood thinners — so it's not right for everyone.
Does this product help with constipation?
Blond psyllium (Che Qian Zi) in the formula is rated effective for constipation. However, it can cause gas, bloating, or diarrhea in some people, and you need to drink plenty of water with it to avoid bowel obstruction. If constipation is your main concern, ask your doctor whether psyllium alone or a different approach makes sense for you.
Why does this product interact with so many medications?
The herbs in Natura 801 affect how your body absorbs or processes drugs in several ways. Panax notoginseng may thin the blood and change how your liver breaks down certain medications. Blond psyllium is a fiber that binds to drugs in your gut and slows their absorption. Poria mushroom can enhance sedative effects. That's why it's critical to check your specific medications before starting.
What are the most common side effects?
Panax notoginseng may cause dry mouth, insomnia, nausea, nervousness, or rash. Blond psyllium may cause gas, bloating, abdominal pain, constipation, or diarrhea. Angelica can cause photosensitivity (sun sensitivity) and constipation. Allergic reactions are rare but have been reported with the mushroom ingredients.
Can I take Natura 801 with caffeine or stimulants?
Panax notoginseng may reduce caffeine levels and effectiveness, and pagoda tree may slow caffeine clearance. If you rely on caffeine for energy or take stimulant medications, talk with your pharmacist about timing and whether this product is a good fit for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Natura 801 label
Go deeper

The Full Monographs Behind Natura 801’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Poria Mushroom

Interacts with 417 drugs

Poria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scientific evidence in humans is very limited,...

Read the full Poria Mushroom monograph →
Herb & supplement monograph

Panax Notoginseng

Interacts with 207 drugs

Panax notoginseng (sanqi or tienchi ginseng) is a traditional Chinese herb most often used to help with bleeding, bruising, and circulation. Human evidence for these uses is limited and most...

Read the full Panax Notoginseng monograph →
Herb & supplement monograph

Pagoda Tree

Interacts with 29 drugs

Pagoda Tree (Styphnolobium japonicum, also called the Japanese pagoda tree) is a traditional Asian medicinal plant best known as a natural source of the flavonoid rutin. While it has a long...

Read the full Pagoda Tree monograph →
Herb & supplement monograph

Angelica Archangelica

Interacts with 335 drugs

Angelica archangelica is a tall aromatic herb used traditionally for digestive complaints, poor appetite, and to flavor foods and liqueurs. Solid human evidence for its health benefits is li...

Read the full Angelica Archangelica monograph →
Herb & supplement monograph

Blond Psyllium

Interacts with 2,025 drugs

Blond psyllium is a soluble fiber from the seed husks of Plantago ovata, and it is one of the better-studied fiber supplements. It can help with both constipation and diarrhea and may modest...

Read the full Blond Psyllium monograph →
Sources

Sources & How We Checked

Natura 801's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 51 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Poria Mushroom 3 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
  3. Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.

See these in context on the Poria Mushroom monograph →

Panax Notoginseng 15 references
  1. Huang KC. The Pharmacology of Chinese Herbs. 2nd ed. New York, NY: CRC Press, LLC 1999:101-102.
  2. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica. Seattle, WA: Eastland Press, 1996:359-60.
  3. Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb(1)-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003;18:2166-8..
  4. Du XF, Yin XP, Zhang GL, Shi HJ, Shao MH. Interstitial granulomatous drug reaction to a Chinese herb extract. Eur J Dermatol. 2012 May-Jun;22(3):419-20. PubMed
  5. Liu R, Qin M, Hang P, Liu Y, Zhang Z, Liu G. Effects of Panax notoginseng saponins on the activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in rats in vivo. Phytother Res. 2012 Aug;26(8):1113-8.
  6. Shang Q, Xu H, Liu Z, Chen K, Liu J. Oral Panax notoginseng Preparation for Coronary Heart Disease: A Systematic Review of Randomized Controlled Trials. Evid Based Complement Alternat Med. 2013;2013:940125.
  7. Tian Z, Pang H, Du S, Lu Y, Zhang L, Wu H, Guo S, Wang M, Zhang Q. Effect of Panax notoginseng saponins on the pharmacokinetics of aspirin in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Jan 1;1040:136-143. PubMed
  8. Xu D, Huang P, Yu Z, Xing DH, Ouyang S, Xing G. Efficacy and Safety of Panax notoginseng Saponin Therapy for Acute Intracerebral Hemorrhage, Meta-Analysis, and Mini Review of Potential Mechanisms of Action. Front Neurol. 2015 Jan 7;5:274. PubMed
  9. Yang X, Xiong X, Wang J. Sanqi panax notoginseng injection for angina pectoris. Evid Based Complement Alternat Med. 2014;2014:963208. PubMed
  10. Yin Z, Ma L, Xu J, Xia J, Luo D. Pustular drug eruption due to Panax notoginseng saponins. Drug Des Devel Ther. 2014 Jul 16;8:957-61. PubMed
  11. Song H, Wang P, Liu J, Wang C. Panax notoginseng Preparations for Unstable Angina Pectoris: A Systematic Review and Meta-Analysis. Phytother Res. 2017 Jun 20.
  12. Tian Z, Pang H, Zhang Q, et al. Effect of aspirin on the pharmacokinetics and absorption of panax notoginsengsaponins. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jan 2;1074-75.
  13. Li C, Xu T, Zhou P, et al. Post-marketing safety surveillance and re-evaluation of Xueshuantong injection. BMC Complement Altern Med. 2018;18(1):277. PubMed
  14. Liu L, Shen XJ, Xue LJ, Yao SK, Zhu JY. Submucosal hematoma with a wide range of lesions, severe condition and atypical clinical symptoms: A case report. World J Clin Cases 2021;9(20):5683-5688. PubMed
  15. Qian J, Chen W, Wu J, et al. Effects and Mechanism of Action of Panax notoginseng Saponins on the Pharmacokinetics of Warfarin. Eur J Drug Metab Pharmacokinet 2022;47(3):331-342. PubMed

See these in context on the Panax Notoginseng monograph →

Pagoda Tree 2 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Chen, Y., Xiao, C. Q., He, Y. J., Chen, B. L., Wang, G., Zhou, G., Zhang, W., Tan, Z. R., Cao, S., Wang, L. P., and Zhou, H. H. Genistein alters caffeine exposure in healthy female volunteers. Eur.J Clin.Pharmacol. 2011;67(4):347-353. PubMed

See these in context on the Pagoda Tree monograph →

Angelica Archangelica 3 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Ojala T, Vuorela P, Kiviranta J, et al. A bioassay using Artemia salina for detecting phototoxicity of plant coumarins. Planta Med 1999;65:715-8. PubMed
  3. Sigurdsson S, Geirsson G, Gudmundsdottir H, Egilsdottir PB, Gudbjarnason S. A parallel, randomized, double-blind, placebo-controlled study to investigate the effect of SagaPro on nocturia in men. Scand J Urol. 2013;47(1):26-32. PubMed

See these in context on the Angelica Archangelica monograph →

Blond Psyllium 28 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Agha FP, Nostrant TT, Fiddian-Green RG. Giant colonic bezoar: a medication bezoar due to psyllium seed husks. Am J Gastroenterol 1984;79:319-21.
  7. Anderson JW, Allgood LD, Lawrence A, et al. Cholesterol-lowering effects of psyllium intake adjunctive to diet therapy in men and women with hypercholesterolemia: meta-analysis of 8 controlled trials. Am J Clin Nutr 2000;71:472-9. PubMed
  8. Suhonen R, Kantola I, Bjorksten F. Anaphylactic shock due to ingestion of psyllium laxative. Allergy 1983;38:363-5. PubMed
  9. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  10. Freeman GL. Psyllium hypersensitivity. Ann Allergy 1994;73:490-2.
  11. Morgan MS, Arlian LG, Vyszenski-Moher DL, et al. English plantain and psyllium: lack of cross-allergenicity by crossed immunoelectrophoresis. Ann Allergy Asthma Immunol 1995;75:351-9.
  12. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  13. Schneider RP. Perdiem causes esophageal impaction and bezoars. South Med J 1989;82:1449-50. PubMed
  14. Shulman LM, Minagar A, Weiner WJ. Perdiem causing esophageal obstruction in Parkinson's disease. Neurology 1999;52:670-1. PubMed
  15. James JM, Cooke SK, Barnett A, Sampson HA. Anaphylactic reactions to a psyllium-containing cereal. J Allergy Clin Immunol 1991;88:402-8.. PubMed
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See these in context on the Blond Psyllium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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