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Dietary supplement

Natural Astaxanthin 12 mg Ingredients & Drug Interactions

by Epic 4 Health

Natural Astaxanthin 12 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Natural Astaxanthin 12 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Natural Astaxanthin 12 mg is a dietary supplement by Epic 4 Health with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Natural Astaxanthin 12 mg by Epic 4 Health

Ask about any prescription or over-the-counter medication and we check it for interactions with Natural Astaxanthin 12 mg by Epic 4 Health — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Natural Astaxanthin 12 mg by Epic 4 Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: astaxanthin 12 mg per softgel. Astaxanthin is a red pigment (carotenoid) found in algae and seafood.

The capsule also contains inactive ingredients — kosher beef gelatin, extra virgin organic olive oil, vegetable glycerin, sunflower lecithin, purified water, D-alpha-tocopherol, refined sunflower oil, and other tocopherols — which help deliver the astaxanthin.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Astaxanthin product and its label doesn't state a use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on astaxanthin for common uses — age-related cognitive decline, macular degeneration, aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome — is insufficient to rate. We don't hold reliable data showing it works or doesn't work for these conditions.

If you're considering this supplement for a specific purpose, talk with your pharmacist about what the current research shows.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects are abdominal pain, diarrhea, and red fecal color — the red color is harmless and comes from the pigment itself.

At the dose in this product (12 mg), these effects were uncommon in trials; higher doses of 40 mg daily caused severe stomach pain in a small number of people. Not enough safety data exist during pregnancy or while breastfeeding, so the safety data advises against use in both situations.

Talk with your doctor or pharmacist for personalized guidance if you're pregnant or nursing.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this, check whether you use any drugs broken down by the CYP3A4 enzyme (Moderate concern) or CYP2B6 enzyme (Moderate concern). These include many statins, blood pressure medications, immunosuppressants, and some antidepressants.

Use the medication checker on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Astaxanthin may be worth considering if you're interested in a pigmented antioxidant and your medications don't interact with it — but the evidence for what it does isn't established yet. Anyone taking drugs that rely on CYP3A4 or CYP2B6 (check your list below) should clear this with their pharmacist first.

Pregnant or breastfeeding? Skip it unless your doctor says otherwise.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Natural Astaxanthin 12 mg, straight from the product label.

Brand Epic 4 Health
Barcode (UPC) 850000851054
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 229903
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Natural Astaxanthin 12 mg by Epic 4 Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
850000851054
IngredientAmount% DV
Astaxanthin12 mg--

Other ingredients: Kosher Beef Gelatin, extra virgin organic Olive Oil, Vegetable Glycerin, Sunflower Lecithin, purified Water, D-Alpha-Tocopherol, refined Sunflower Oil, Other Tocopherols

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Free of: milk, egg, fish, shellfish, tree nuts, wheat, peanuts, soybeans and corn. Non-GMO, gluten free, soy free

Manufactured in a cGMP Certified U.S.A. Facility.

Supports healthy skin, eye health and immune function Promotes healthy inflammatory response

Precautions

Caution: Before using any dietary supplement, pregnant or lactating women should consult with a physician or health professional.

Keep out of reach of children.

Do not use if safety seal is broken or missing.

Storage

Keep bottle tightly closed. Store between 15 degrees - 30 degrees C (59 degrees - 86 degrees F).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

To report a serious adverse event or to obtain product information contact 1-800-866-0978.

Brand IP Statement(s)

AstaZine is a registered trademark of BGG.

Formula

AstaZine

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults: Take one (1) softgel daily as a dietary supplement or as recommended by your healthcare professional.

Seals/Symbols

GMP Quality Assured

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Natural Astaxanthin 12 mg by Epic 4 Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Natural Astaxanthin 12 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Natural Astaxanthin 12 mg by Epic 4 Health

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Astaxanthin

Interacts with
671 drugs
12 mg per serving Form: organic Haematoccous pluvialis

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

Other (inactive) ingredients: Kosher Beef Gelatin, Extra virgin organic Olive Oil, Vegetable Glycerin, Sunflower Lecithin, Purified Water, D-Alpha-Tocopherol, Refined Sunflower Oil, Other Tocopherols. These complete the product’s ingredient list but are not active constituents.

Interaction report

Natural Astaxanthin 12 mg by Epic 4 Health Drug Interactions

Want to check YOUR meds against Natural Astaxanthin 12 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

Astaxanthin 671

Individual Drug Interactions

The ingredients in Natural Astaxanthin 12 mg interact with 671 drugs. Click any drug to see the details.

1 of the 1 ingredient in Natural Astaxanthin 12 mg interact with drugs. Each result below shows which ingredient is responsible. Astaxanthin

Each ingredient & the kinds of drugs it affects

For each ingredient in Natural Astaxanthin 12 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Astaxanthin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Natural Astaxanthin 12 mg, from the product label.

Epic 4 Health

See all Epic 4 Health products
Name
Epic 4 Health
Street Address
30 New York Avenue
City
Westbury
State
NY
ZipCode
11590
Phone Number
1-800-866-0978
Web Address
www.Epic4Health.com
Pharmacist Counseling Corner

Natural Astaxanthin 12 mg by Epic 4 Health: Common Questions

Does Natural Astaxanthin 12 mg by Epic 4 Health interact with any medications?
Yes. Based on its ingredients, Natural Astaxanthin 12 mg has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Natural Astaxanthin 12 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is astaxanthin?
Astaxanthin is a red pigment — a type of carotenoid — that comes from algae and seafood. It's a type of antioxidant.
Will this supplement make my stool red?
Yes, it can. Red or pink stool color is a documented side effect and comes directly from the astaxanthin pigment itself. It's harmless and should go away if you stop taking it.
Is this safe if I'm pregnant or breastfeeding?
No — the safety data advises against it in both situations because there isn't enough research. Talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or nursing.
Does this product contain any common allergens?
The product facts don't list allergen data, so I can't tell you for certain. Check the label closely or contact Epic 4 Health directly if you have allergies.
What conditions does astaxanthin treat?
We don't hold reliable evidence that astaxanthin treats age-related cognitive decline, macular degeneration, aging skin, Alzheimer disease, athletic performance problems, or carpal tunnel syndrome. The evidence for these uses is insufficient to rate.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Natural Astaxanthin 12 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Natural Astaxanthin 12 mg label
Go deeper

The Full Monographs Behind Natural Astaxanthin 12 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Natural Astaxanthin 12 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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