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Dietary supplement

Oil Of Oregano Ingredients & Drug Interactions

by Vitamer Laboratories

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Oil Of Oregano is a dietary supplement by Vitamer Laboratories with 1 active ingredient. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oregano leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Oil Of Oregano by Vitamer Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: oregano leaf extract. It's a concentrated form of oregano — the herb you cook with — but made into a supplement capsule so you can take a larger dose than you'd get from food seasoning.

The capsules also contain two inactive ingredients (soy lecithin and vegetable cellulose), which are used as a binder and capsule material to hold the extract together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Oregano's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: antimicrobial and antifungal support.
  • We looked for evidence on: Intestinal parasite infection, Tinea capitis, Tinea corporis, Tinea pedis, Warts, Upper respiratory tract infection (URTI) — and 4 related terms.
  • The closest evidence on file: Oregano is rated "Insufficient Reliable Evidence To Rate" for Acne (Natural Medicines).
  • Also on file: Oregano is rated "Insufficient Reliable Evidence To Rate" for Bronchitis, Upper respiratory tract infection (URTI), Cough, Intestinal parasite infection, and more.

The evidence for oregano leaf extract is not established in our data. The product facts show insufficient reliable evidence to rate it for acne, bronchitis, asthma, headache, or upper respiratory tract infection — the conditions people often ask about.

That doesn't mean it doesn't work, but rather that the research we have isn't strong enough yet to say either way.

The evidence, ingredient by ingredient Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oregano is well tolerated when you eat it as a food seasoning. The main caution is that concentrated supplement forms like this one are much stronger and haven't been studied as thoroughly as food amounts.

The most common side effect is gastrointestinal upset — stomach discomfort or cramping. Rarely, some people have reported allergic reactions, including serious ones like anaphylaxis.

During pregnancy, the safety data advises against medicinal or supplement amounts — food amounts are likely fine. While breastfeeding, there isn't enough data to know whether the supplement is safe, so talk with your doctor or pharmacist about whether it's right for you.

Oregano is a member of a plant family that can trigger allergies in sensitive people, so if you've had reactions to oregano, thyme, or related herbs, be cautious.

Side effects, ingredient by ingredient Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before starting if you take blood thinners or antiplatelet drugs (such as warfarin, apixaban, aspirin, or clopidogrel) — oregano may increase bleeding risk. Also check if you take any diabetes medications, since oregano may lower blood sugar.

No other medication interactions are documented for this ingredient in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood thinners, antiplatelet drugs, or diabetes medications, this supplement isn't for you without checking first — the interaction risk is real. For other uses, the evidence to support it simply isn't there yet.

Talk with your own doctor or pharmacist before starting it, especially if you're pregnant, breastfeeding, or have a history of herb allergies.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oil Of Oregano, straight from the product label.

Brand Vitamer Laboratories
Barcode (UPC) 719985921315
Net contents 60 Liquid-Filled Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Dec 23, 2016
DSLD ID 69269
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oil Of Oregano by Vitamer Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
719985921315
IngredientAmount% DV
Calories5 Calorie(s)--
Oregano leaf extract230 mg--

Other ingredients: Soy Lecithin, Vegetable Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Contains no artificial colors, flavors or preservatives; no wheat, gluten, milk, eggs, peanuts, tree nuts, crustacean shellfish or fish.

Suitable for vegans.

Precautions

Pregnant or lactating women should consult their healthcare professional before using this product.

Keep out of reach of children.

General Statements

Oil of Oregano is derived from mountain-grown Oregano in the Mediterranean. Used for centuries as an anti-microbial and anti-fungal agent, it has also been shown to exhibit antioxidant properties, largely due to the phenol Carvacrol.

Each 1 capsule contains 2,300 mg crude herb equivalent.

We guarantee our supplements for potency and purity

Ecologically wildcrafted

Provides antioxidant support

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Suggested Use: Take one capsule with a small amount of warm water two times daily between meals.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Double Verified Gluten Free

General

VVL 921-60G

See for yourself

Oil Of Oregano by Vitamer Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Oil Of Oregano by Vitamer Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Oregano leaf extract

Interacts with
208 drugs
230 mg per serving Form: Carvacrol, Thymol

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Oregano leaf extract monograph & interactions

Other (inactive) ingredients: Soy Lecithin, Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oil Of Oregano by Vitamer Laboratories Drug Interactions

Want to check YOUR meds against Oil Of Oregano?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Oil Of Oregano with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oregano leaf extract2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Oil Of Oregano, from the product label.

Vitamer Laboratories

See all Vitamer Laboratories products
Phone Number
1-888-710-0006
Pharmacist Counseling Corner

Oil Of Oregano by Vitamer Laboratories: Common Questions

Does Oil Of Oregano by Vitamer Laboratories interact with any medications?
Yes. Based on its ingredients, Oil Of Oregano has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oil Of Oregano contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Oil of Oregano while pregnant?
The safety data advises against medicinal or supplement amounts during pregnancy. Food amounts of oregano — like what you'd use to season a meal — are likely fine. Talk with your doctor or pharmacist before starting this supplement if you're pregnant or planning to be.
What's the most common side effect?
Gastrointestinal upset — stomach discomfort or nausea — is the most common. Most people tolerate oregano well when used in food amounts, but concentrated supplements haven't been studied as much. Serious allergic reactions are rare but have been reported in sensitive people.
Does this product actually work for anything?
The evidence isn't established in our data. We don't have reliable research to confirm oregano leaf extract works for acne, bronchitis, asthma, headache, or upper respiratory infections — the conditions people often try it for. That doesn't mean it doesn't help, just that the science isn't there yet.
Is this safe to breastfeed while taking?
There isn't enough data to know whether concentrated oregano supplements are safe while breastfeeding. Food amounts are likely fine, but for the supplement, talk with your doctor or pharmacist for personalized advice.
What if I'm allergic to oregano or thyme?
Be cautious. Oregano is part of a plant family that shares allergens with thyme and other herbs in the same group. Allergic reactions to oregano — including serious ones — have been reported in sensitive people. If you've had a reaction to these herbs before, check with your pharmacist or doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Oil Of Oregano is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oil Of Oregano label
Sources

Sources & How We Checked

Oil Of Oregano's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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