No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Olive Leaf Ingredients & Drug Interactions

by GNC Herbal Plus Standardized

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Olive Leaf is a dietary supplement by GNC Herbal Plus Standardized with 1 active ingredient. Its ingredients are commonly taken for heart health, high blood pressure, high cholesterol.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Olive Leaf by GNC Herbal Plus Standardized

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: olive leaf extract. The inactive ingredients are cellulose and a vegetable cellulose capsule, which serve as filler and capsule material.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Olive product and its label doesn't state a use — see Olive's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold for olive leaf extract is not established. The data shows insufficient reliable evidence to rate it for osteoporosis, dyspepsia (indigestion), exercise-induced respiratory infections, herpes zoster (shingles), influenza, or osteoarthritis.

That means studies so far haven't been robust enough to say whether it works for these uses.

The evidence, ingredient by ingredient Olive

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Olive as a food and oil is very safe, but concentrated supplements like this one are less studied, so safety data is limited. When used in typical food amounts, olive fruit is well tolerated.

Most people report no problems with olive leaf extract, though a small number of trial participants reported headache and stomach discomfort. One person reported skin changes and acne.

Olive tree pollen can trigger seasonal respiratory allergies if you're sensitive to it. Because the long-term safety of concentrated olive leaf supplements isn't well established, talk with your doctor before starting unless they've already approved it.

Side effects, ingredient by ingredient Olive

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for olive leaf extract. Check your exact medications with the tool on this page or with your doctor or pharmacist before starting.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you're curious about olive leaf for general wellness, this product is generally well tolerated at typical doses. The evidence for treating specific conditions is weak, so don't expect proven results for any particular health issue.

Talk with your doctor or pharmacist before you start, especially if you have any health conditions or take medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Olive Leaf, straight from the product label.

Brand GNC Herbal Plus Standardized
Barcode (UPC) 048107064624
Net contents 100 Vegetarian Capsules
Market status On market
Date entered into DSLD Oct 26, 2011
DSLD ID 708
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Olive Leaf by GNC Herbal Plus Standardized, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
048107064624
IngredientAmount% DV
Olive Leaf Extract500 mg--

Other ingredients: Cellulose, Vegetable Cellulose Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Potency verified by GNC procedure #5351. Conforms to USP <2091> for weight. Meets UPS <2040> disintegration.

FDA Disclaimer Statement

* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

HERBAL SUPPLEMENT

Formulation

No Sugar, No Artficial Colors, No Artifical Flavors, Sodium Free, No Wheat, No Gluten, No Soy, No Dairy, Yeast Free.

Precautions

KEEP OUT OF REACH OF CHILDREN.

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition. Discontinue use two weeks prior to surgery.

Storage

Store in a cool, dry place.

General

CODE 196131 EKG

General Statements

Standardized Extract 500 mg

Supports General Well-Being*

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one capsule daily.

See for yourself

Olive Leaf by GNC Herbal Plus Standardized label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Olive Leaf by GNC Herbal Plus Standardized

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Olive Leaf Extract

No known
interactions
500 mg per serving Form: Oleuropein

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...

Olive Leaf Extract monograph & interactions

Other (inactive) ingredients: Cellulose, Vegetable Cellulose Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Olive Leaf by GNC Herbal Plus Standardized Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Olive Leaf. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Olive Leaf, from the product label.

GNC Herbal Plus Standardized

See all GNC Herbal Plus Standardized products
Phone Number
1-888-462-2548
Pharmacist Counseling Corner

Olive Leaf by GNC Herbal Plus Standardized: Common Questions

Does Olive Leaf by GNC Herbal Plus Standardized interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Olive Leaf. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Olive Leaf contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is olive leaf extract?
It's a concentrated form of compounds from olive leaves. While olives and olive oil as foods are very safe, this supplement form is less studied and we know less about its long-term safety profile.
Will it help with my immune system or a cold?
The data we hold shows insufficient evidence to say whether olive leaf works for influenza, exercise-induced respiratory infections, or any other condition. Studies haven't been strong enough to prove it works.
What side effects should I expect?
Most people tolerate it well. Some trial participants reported headache and stomach discomfort. One person reported skin changes. If you're sensitive to olive tree pollen, it might trigger allergy symptoms.
Is it safe to take while pregnant or breastfeeding?
We don't have safety data on file for olive leaf extract in pregnancy or lactation. Talk with your doctor or pharmacist before taking it if you're pregnant or breastfeeding — they can give you personalized advice based on your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Olive Leaf is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Olive Leaf label
Go deeper

The Full Monographs Behind Olive Leaf’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Olive Leaf's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

See these in context on the Olive monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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