Interactions on record — worth a quick check against your medications. Based on 6 of 7 ingredients. Check your meds →
Dietary supplement

Omega Man Mocha Java Swirl Ingredients & Drug Interactions

by Barlean's

Liquid Category: Botanical With Nutrients
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Omega Man Mocha Java Swirl is a dietary supplement by Barlean's with 7 active ingredients. Its ingredients are commonly taken for brain and cognitive health, eye and vision health, fetal and infant development.Based on those ingredients, 983 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin E, Omega-3 Fatty Acids, Oleic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Omega Man Mocha Java Swirl by Barlean's

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 13 of its 13 active ingredients.
  • “Omega-3 Fatty Acids” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Omega-6 Fatty Acids” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Omega-9 Fatty Acids” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Omega Man Mocha Java Swirl contains 13 active ingredients centered on omega fatty acids — omega-3, omega-6, and omega-9 blends — plus individual components like eicosapentaenoic acid and docosahexaenoic acid (the long-chain omega-3s). You'll also find vitamin E, oleic acid, alpha-linolenic acid, linoleic acid, and other polyunsaturated and monounsaturated fats.

Styrian pumpkin seed oil and maca extract round out the active blend. The product also contains inactive ingredients like water, xylitol, natural flavors, cocoa powder, coffee extracts, and various gums and stabilizers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: omega-3 support for men's health and energy.
  • We looked for evidence on: Age-related cognitive decline, Age-related macular degeneration (AMD), Age-related testosterone deficiency, Alzheimer disease, Atherosclerosis, Atrial fibrillation — and 4 related terms.
  • The strongest evidence on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Vitamin E is rated "Possibly Effective" for Alzheimer disease.
  • Also on file: Oleic Acid is rated "Possibly Effective" for Coronary heart disease (CHD).

Vitamin E in this product is effective for vitamin E deficiency and ataxia with vitamin E deficiency (a rare neurological disorder). It's possibly effective for Alzheimer disease, beta-thalassemia, and glucose-6-phosphate dehydrogenase (G6PD) deficiency, as well as intracranial hemorrhage.

Oleic acid is possibly effective for high cholesterol and coronary heart disease. Pumpkin seed oil is possibly effective for benign prostatic hyperplasia (enlarged prostate), though evidence is insufficient for its use in hair loss, bladder inflammation, parasite infection, or urinary tract infections.

For maca extract, the evidence we hold doesn't support any condition — reliability is insufficient across all conditions listed.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin E from usual dietary amounts is well tolerated, but high-dose long-term supplements carry risks including bleeding and rare cases of hemorrhagic stroke. Vitamin E is possibly safe in pregnancy at normal dietary levels, but you should avoid high-dose supplements unless your doctor directs otherwise.

During breastfeeding, normal dietary amounts are fine, though high-dose supplements need medical approval; some data raises a flag on lactation safety at supplement levels. Pumpkin seed oil is generally safe for most adults, though concentrated supplements during pregnancy and breastfeeding lack solid safety data — food amounts are fine.

Maca extract is generally well tolerated as a food, though raw maca may cause stomach pain; safety data for supplements is insufficient in pregnancy and breastfeeding, and the product advises against both. Oleic acid from food is safe; concentrated supplements in pregnancy and breastfeeding lack good study.

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Pumpkin, Vitamin E, Oleic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; cancer treatments; diabetes medications; lithium.
  • For scale: 846 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking this product if you use blood thinners (anticoagulants) or antiplatelet drugs, or if you take warfarin — vitamin E increases bleeding risk. Tell your doctor or pharmacist if you're on diabetes medications, as oleic acid may strengthen their effect.

If you take lithium, chemotherapy drugs (especially alkylating agents or antitumor antibiotics), cyclosporine, or niacin, get medical advice first. No interactions are documented for the omega-3 and omega-6 components we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is an omega fatty acid blend with added antioxidant support from vitamin E and pumpkin seed oil. If you take blood thinners, diabetes medications, or lithium, or if you're on certain chemotherapy drugs or niacin, talk with your doctor or pharmacist before starting — the interactions could affect how your medications work or your bleeding risk.

Pregnant or breastfeeding people should discuss this with their healthcare provider first, especially due to maca and the high-dose vitamin E potential.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 13 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Omega Man Mocha Java Swirl, straight from the product label.

Brand Barlean's
Barcode (UPC) 705875000444
Net contents 8 oz.; 227 Gram(s)
Market status On market
Date entered into DSLD Jul 24, 2015
DSLD ID 47101
Product type Botanical With Nutrients
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Omega Man Mocha Java Swirl by Barlean's, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tbsp
Maximum serving Sizes:
1 Tbsp
Servings per container
14
UPC/BARCODE
705875000444
IngredientAmount% DV
Calories60 {Calories}--
Total Carbohydrates6 Gram(s)2%
Sugar0 Gram(s)--
Calories from Fat40 {Calories}--
Omega-3 Fatty Acids0 NP--
Eicosapentaenoic Acid600 mg--
Docosahexaenoic Acid400 mg--
Saturated Fat1 Gram(s)5%
Polyunsaturated Fat2 Gram(s)--
Cholesterol25 mg8%
Omega-6 Fatty Acids0 NP--
Omega-9 Fatty Acids0 NP--
Total Fat4.5 Gram(s)7%
Trans Fat0 Gram(s)--
Vitamin E6 IU20%
Other Omega-3 Fatty Acids140 mg--
Docosapentaenoic Acid80 mg--
Linoleic Acid300 mg--
Oleic Acid470 mg--
Alpha-Linolenic Acid30 mg--
Monounsaturated Fat1 Gram(s)--
Other Omega-6 Fatty Acids110 mg--
Styrian Pumpkin seed oil500 mg--
Maca extract300 mg--

Other ingredients: Water, Omega Man Oil Blend, Xylitol, Glycerine, Natural flavors, Gum Arabic, Maca extract 4:1, Cocoa powder, decaffeinated Coffee extract, decaffeinated Coffee powder, Sunflower Lecithin, Xanthan Gum, Guar Gum, Antioxidant Blend, Sorbic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

100% SATISFACTION GUARANTEED Bruce Barlean

Smoothie Taste and Texture

Superior Absorbability

PRODUCT OF U.S.A.

ESTd 1989

~ Great Tasting, All-Natural Flavor

With the rich and creamy taste of mocha java, just a spoonful a day of Omega Man Swirl provides a supercharged dose of Omega-3 without the fishy taste and oily texture of standard fish oil.

PROVEN MORE ABSORBABLE: Barlean's Omega Man Swirl is micronized for rapid and complete digestion, making it 9-times more absorbable than typical fish oil.

Formula

Barlean's High Potency Omega Man Swirl is the only Omega-3 supplement formulated specifically for men that has the delicious taste and texture of a smoothie.

Now with 1,000 mg of EPA/DHA per serving, Omega Man Swirl combines Barlean's Fresh Catch(R) Fish Oil, rare Styrian Pumpkin Seed Oil and Maca - long revered as a natural source for energy and endurance - to create the Ultimate Men's Health and Vitality Formula.

EPA/DHA 1,000 mg PER SERVING

Styrian Pumpkin Seed Oil Maca

Seals/Symbols

Barlean's ORGANIC OILS FROM OUR FAMILY TO YOURS

{recycle} 2

{QR Code}

FDA Statement of Identity

OMEGA-3 Fish Oil SUPPLEMENT

General

69272-00

Formulation

~ Gluten-Free, Sugar-Free, Non-GMO

Suggested/Recommended/Usage/Directions

SUGGESTED USE: 1 Tbsp. daily. Can be taken straight or mixed into beverages, oatmeal, ice cream or yogurt.

SHAKE WELL.

Storage

Refrigerate for quality.

Precautions

Keep out of reach of children.

Do not give to pets.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Omega Man Mocha Java Swirl by Barlean's label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Omega Man Mocha Java Swirl by Barlean's

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tbsp Dosage formLiquid Servings per container14 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

0 Gram(s) per serving

Omega-3 Fatty Acids

Interacts with
375 drugs
0 NP per serving

DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and gen...

Omega-3 Fatty Acids monograph & interactions
  • › Eicosapentaenoic Acid
  • › Docosahexaenoic Acid
  • › Other Omega-3 Fatty Acids
  • › Docosapentaenoic Acid
  • › Alpha-Linolenic Acid

Omega-6 Fatty Acids

No known
interactions
0 NP per serving

Omega-6 fatty acids are essential fats your body needs but cannot make on its own, and most people get plenty from everyday foods like vegetable oils,...

Omega-6 Fatty Acids monograph & interactions
  • › Linoleic Acid
  • › Other Omega-6 Fatty Acids

Omega-9 Fatty Acids

0 NP per serving

Vitamin E

Interacts with
764 drugs
6 IU per serving

Vitamin E is an essential fat-soluble vitamin and antioxidant that most people get in adequate amounts from a normal diet. Supplements can help correc...

Vitamin E monograph & interactions

Styrian Pumpkin seed oil

Interacts with
1 drug
500 mg per serving

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...

Styrian Pumpkin seed oil monograph & interactions

Maca extract

No known
interactions
300 mg per serving

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca extract monograph & interactions

Other (inactive) ingredients: Water, Omega Man Oil Blend, Xylitol, Glycerine, Natural flavors, Gum Arabic, Maca extract 4:1, Cocoa powder, Decaffeinated Coffee extract, Decaffeinated Coffee powder, Sunflower Lecithin, Xanthan Gum, Guar Gum, Antioxidant Blend, Sorbic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Omega Man Mocha Java Swirl by Barlean's Drug Interactions

Want to check YOUR meds against Omega Man Mocha Java Swirl?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
983Drugs
982 Moderate 1 Minor

Ingredients driving the most interactions

Vitamin E 764

Each ingredient & the kinds of drugs it affects

For each ingredient in Omega Man Mocha Java Swirl with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin E8 drug types · 764 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin E might reduce the effectiveness of alkylating agents.
There's concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin E have on chemotherapy. Advise patients to consult their oncologist before using vitamin E supplements, especially in high doses.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Concomitant use of vitamin E and anticoagulant or antiplatelet agents might increase the risk of bleeding.
Vitamin E seems to inhibit of platelet aggregation and antagonize the effects of vitamin K-dependent clotting factors. These effects appear to be dose-dependent, and are probably only likely to be clinically significant with doses of at least 800 units daily. Mixed tocopherols, such as those found in food, might have a greater antiplatelet effect than alpha-tocopherol. RRR alpha-tocopherol (natural vitamin E) 1000 IU daily antagonizes vitamin K-dependent clotting factors. Advise patients to avoid high doses of vitamin E, especially in people with low vitamin K intake or other risk factors for bleeding.

Likelihood Possible Evidence B
Antitumor Antibiotics

Theoretically, antioxidant effects of vitamin E might reduce the effectiveness of antitumor antibiotics.
There's concern that antioxidants could reduce the activity of antitumor antibiotic drugs such as doxorubicin, which generate free radicals. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin E have on chemotherapy involving antitumor antibiotics. Advise patients to consult their oncologist before using vitamin E supplements, especially in high doses.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

A specific form of vitamin E might increase absorption and levels of cyclosporine.
There is some evidence that one specific formulation of vitamin E (D-alpha-tocopheryl-polyethylene glycol-1000 succinate, TPGS, tocophersolan, Liqui-E) might increase absorption of cyclosporine. This vitamin E formulation forms micelles which seems to increase absorption of cyclosporine by 40% to 72% in some patients. However, this interaction is unlikely to occur with the usual forms of vitamin E.

Likelihood Unlikely Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, vitamin E might induce metabolism of CYP3A4, possibly reducing the levels CYP3A4 substrates.
Vitamin E appears to bind with the nuclear receptor, pregnane X receptor (PXR), which results in increased expression of CYP3A4. Although the clinical significance of this is not known, use caution when considering concomitant use of vitamin E and other drugs affected by these enzymes.

Likelihood Possible Evidence D
Selumetinib (Koselugo)

Taking selumetinib with vitamin E can result in a total daily dose of vitamin E that exceeds safe limits and therefore might increase the risk of bleeding.
Selumetinib contains 48-54 IU vitamin E per capsule. The increased risk of bleeding with vitamin E appears to be dose-dependent. Be cautious when using selumetinib in combination with supplemental vitamin E, especially in patients at higher risk of bleed, such as those with chronic conditions and those taking antiplatelet drugs.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Using vitamin E with warfarin might increase the risk of bleeding.
Due to interference with production of vitamin K-dependent clotting factors, use of more than 400 IU of vitamin E daily with warfarin might increase prothrombin time (PT), INR, and the risk of bleeding,. At a dose of 1000 IU per day, vitamin E can antagonize vitamin K-dependent clotting factors even in people not taking warfarin. Limited clinical evidence suggests that doses up to 1200 IU daily may be used safely by patients taking warfarin, but this may not be applicable in all patient populations.

Likelihood Possible Evidence B
Niacin

Vitamin E might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises high-density lipoprotein (HDL) cholesterol levels in people with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50%. Vitamin E alone combined with a statin does not seem to decrease HDL levels. It is not known whether the adverse effect on HDL is due to one of the other antioxidants or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A

Omega-3 Fatty Acids3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Although some clinical evidence suggests that DHA might reduce collagen-stimulated platelet aggregation and thromboxane release, most clinical evidence suggests that DHA alone does not affect blood clotting. However, theoretically, when given in combination with EPA as fish oil, concomitant use with anticoagulant or antiplatelet drugs (including aspirin) might increase risk of bleeding.

Likelihood Unlikely Evidence B
Antidiabetes Drugs

Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
In people with type 2 diabetes, including those taking oral hypoglycemic medications, DHA seems to increase fasting blood glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Fish oils containing DHA can lower blood pressure and might have additive effects in patients treated with antihypertensives; use with caution.

Likelihood Probable Evidence B

Oleic Acid1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, oleic acid might increase the effects of antidiabetes drugs. Preliminary clinical research in patients with type 2 diabetes taking oral hypoglycemic drugs shows that eating a diet rich in oleic acid from olive oil decreases fasting blood glucose levels when compared to eating a diet rich in linoleic acid from sunflower oil. It is unknown if taking oleic acid supplements would have this effect or if this change is clinically significant. Until more is known, use caution. Dose adjustment may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B

Styrian Pumpkin seed oil1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Omega Man Mocha Java Swirl, from the product label.

Barlean's

See all Barlean's products
Name
Barlean's Organic Oils
City
Ferndale
State
WA
ZipCode
98248
Phone Number
800-445-3529
Web Address
barleans.com
Pharmacist Counseling Corner

Omega Man Mocha Java Swirl by Barlean's: Common Questions

Does Omega Man Mocha Java Swirl by Barlean's interact with any medications?
Yes. Based on its ingredients, Omega Man Mocha Java Swirl has a known interaction with 983 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Omega Man Mocha Java Swirl contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the omega-3s in this product?
This liquid contains a blend of omega-3 fatty acids, including eicosapentaenoic acid and docosahexaenoic acid — the long-chain forms your body uses. We don't have detailed interaction data for these specific components in our records.
Is this safe to take while pregnant?
The safety picture is mixed. Vitamin E at normal dietary levels is possibly safe in pregnancy, but high-dose supplements should be avoided unless your doctor approves. Maca extract is flagged as unsafe, and oleic acid and pumpkin seed oil lack enough study — talk with your doctor or midwife before starting.
Can I take this while breastfeeding?
Normal dietary amounts of vitamin E are considered likely safe while nursing, but high-dose supplements need medical guidance. Maca extract is flagged as unsafe. Pumpkin seed oil and oleic acid lack solid safety data at supplement levels. Check with your doctor or lactation consultant first.
What does the pumpkin seed oil do?
Pumpkin seed oil is possibly effective for benign prostatic hyperplasia (enlarged prostate), though evidence is insufficient for other uses like hair loss or urinary tract infections. As a food, it's well tolerated; the supplement form is generally safe for most adults.
Does this product have any common side effects?
Vitamin E and pumpkin seed oil are generally well tolerated when taken orally. Pumpkin seed oil has been reported to cause mild abdominal discomfort in trials. Raw or bitter pumpkin is rarely linked to nausea, vomiting, diarrhea, and very rarely hair loss. High-dose vitamin E carries a rare risk of bleeding or hemorrhagic stroke.
Why can't you check all the ingredients?
Several of the omega fatty acids and related compounds — like eicosapentaenoic acid, docosahexaenoic acid, and linoleic acid — don't have detailed interaction data on file with us. That doesn't mean they're unsafe; it means we simply haven't documented them. Your pharmacist can help if you have questions about those.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Omega Man Mocha Java Swirl label
Go deeper

The Full Monographs Behind Omega Man Mocha Java Swirl’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Docosahexaenoic Acid (dha)

Interacts with 375 drugs

DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and generally well tolerated, with the stronges...

Read the full Docosahexaenoic Acid (dha) monograph →
Herb & supplement monograph

Omega-6 Fatty Acids

Omega-6 fatty acids are essential fats your body needs but cannot make on its own, and most people get plenty from everyday foods like vegetable oils, nuts, and seeds. Supplements such as ev...

Read the full Omega-6 Fatty Acids monograph →
Herb & supplement monograph

Oleic Acid

Interacts with 86 drugs

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...

Read the full Oleic Acid monograph →
Herb & supplement monograph

Vitamin E

Interacts with 764 drugs

Vitamin E is an essential fat-soluble vitamin and antioxidant that most people get in adequate amounts from a normal diet. Supplements can help correct a true deficiency, but high-dose vitam...

Read the full Vitamin E monograph →
Herb & supplement monograph

Pumpkin

Interacts with 1 drug

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The evidence for these uses is limited and...

Read the full Pumpkin monograph →
Herb & supplement monograph

Maca

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire and some menopause symptoms, but the evide...

Read the full Maca monograph →
Sources

Sources & How We Checked

Omega Man Mocha Java Swirl's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 158 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Docosahexaenoic Acid (dha) 49 references
  1. Akedo I, Ishikawa H, Nakamura T, et al. Three cases with familial adenomatous polyposis diagnosed as having malignant lesions in the course of a long-term trial using docosahexanoic acid (DHA)-concentrated fish oil capsules (abstract). Jpn J Clin Oncol PubMed
  2. Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
  3. Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59.
  4. Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
  5. Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
  6. Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
  7. FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
  8. Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
  9. Ito Y, Suzuki K, Imai H, et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. Cancer Lett 2001;163:171-8. PubMed
  10. Kris-Ehterton PM, Harris WS, Appel LJ, et al. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57. PubMed
  11. Woodman RJ, Mori TA, Burke V, et al. Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension. Am J Clin Nutr 2002;76:1007-15.. PubMed
  12. Marangell LB, Martinez JM, Zboyan HA, et al. A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am J Psychiatry 2003;160:996-8.. PubMed
  13. Leng GC, Smith FB, Fowkes FG, et al. Relationship between plasma essential fatty acids and smoking, serum lipids, blood pressure and haemostatic and rheological factors. Prostaglandins Leukot Essent Fatty Acids 1994;51:101-8. PubMed
  14. Nelson GJ, Schmidt PS, Bartolini GL, et al. The effect of dietary docosahexaenoic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Lipids 1997;32:1129-36. PubMed
  15. Wheaton DH, Hoffman DR, Locke KG, et al. Biological safety assessment of docosahexaenoic acid supplementation in a randomized clinical trial for X-linked retinitis pigmentosa. Arch Ophthalmol 2003;121:1269-78. PubMed
  16. Malcolm CA, McCulloch DL, Montgomery C, et al. Maternal docosahexaenoic acid supplementation during pregnancy and visual evoked potential development in term infants: a double blind, prospective, randomised trial. Arch Dis Child Fetal Neonatal Ed 2003;88: DOI
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See these in context on the Docosahexaenoic Acid (dha) monograph →

Omega-6 Fatty Acids 20 references
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See these in context on the Omega-6 Fatty Acids monograph →

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Oleic Acid 19 references
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  10. Steffen BT, Duprez D, Szklo M, Guan W, Tsai MY. Circulating oleic acid levels are related to greater risks of cardiovascular events and all-cause mortality: The Multi-Ethnic Study of Atherosclerosis. J Clin Lipidol. 2018;12(6):1404-1412. PubMed
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See these in context on the Oleic Acid monograph →

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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